for A water mediated multicomponent reaction for the synthesis of novel spirooxindole derivatives and their antifungal activity By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00256C, PaperMin Zhang, Liang Shi, Li Chen, Zhengyu Liu, Ting Zhao, Chunyin Zhu, Liuqing YangA total of 27 novel spirooxindoles were synthesized through a water mediated three-component reaction of isatin, 4-aminocoumarin, and 1,3-cyclodicarbonyl compounds. Several compounds showed excellent antifungal activity against Physalospora piricola.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Dehydrative alkynylation of 3-hydroxyisoindolinones with terminal alkynes for the synthesis of 3-alkynylated 3,3-disubstituted isoindolinones By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00190G, PaperKai-Cheng Yang, Shi-Lu Zheng, Zhong Wen, Yu-Shan Zhang, Hai-Liang Ni, Long ChenA HOTf or Fe(OTf)3-catalyzed dehydrative alkynylation of 3-hydroxyisoindolinones with terminal alkynes was developed, which represents a brand-new procedure for the synthesis of 3-alkynylated 3,3-disubstituted isoindolinones.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Use of ionic liquids in amidation reactions for proteolysis targeting chimera synthesis By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00304G, PaperMichela Eleuteri, Jenny Desantis, Gabriele Cruciani, Raimondo Germani, Laura GoracciSelective degradation of disease-causing proteins using proteolysis targeting chimeras (PROTACs) has gained great attention, thanks to its several advantages over traditional therapeutic modalities.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for A rhodium-catalyzed cascade C–H activation/annulation strategy for the expeditious assembly of pyrrolidinedione-fused 1,2-benzothiazines By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00193A, PaperYinsong Wu, Guanghao Shi, Yanan Liu, Yangzilin Kong, Mengdi Wu, Demao Wang, Xiaobing Wu, Yongjia Shang, Xinwei HeWe have developed a cascade annulation strategy triggered by rhodium(III)-catalyzed C–H activation for the expeditious assembly of pyrrolidinedione-fused 1,2-benzothiazines from free NH-sulfoximines with maleimides under mild conditions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Synthesis of Asp-based lactam cyclic peptides using an amide-bonded diaminodiacid to prevent aspartimide formation By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00472H, CommunicationWen-Jie Li, Jun-You Chen, Hui-Xia Zhu, Yi-Ming Li, Yang XuA diaminodiacid (DADA) containing an amide bond can be used in Fmoc solid-phase peptide synthesis (SPPS) of an Asp-based lactam cyclic peptide with no aspartimide formation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for DFT investigation of the DDQ-catalytic mechanism for constructing C–O bonds By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00346B, PaperXiu-Fang Zheng, Da-Gang Zhou, Li-Jun YangThe DDQ-catalytic mechanisms for constructing C–O bonds via H2O and CH3OH as oxygen sources have been investigated with DFT.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Friedel–Crafts reactions for biomolecular chemistry By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00406J, Review Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jun OhataThis review demonstrates advances in Friedel–Crafts alkylation and acylation reactions in a variety of biomolecular chemistry fields.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Albumin–ruthenium catalyst conjugate for bio-orthogonal uncaging of alloc group By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,2992-3000DOI: 10.1039/D4OB00234B, PaperKimberly S. Taylor, Madison M. McMonagle, Schaelee C. Guy, Ariana M. Human-McKinnon, Shumpei Asamizu, Heidi J. Fletcher, Bradley W. Davis, Takashi L. SuyamaAn organo–ruthenium catalyst conjugated to albumin efficiently unmasks an alloc group under physiologically relevant conditions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Expanding the scope of the successive ring expansion strategy for macrocycle and medium-sized ring synthesis: unreactive and reactive lactams By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,2985-2991DOI: 10.1039/D4OB00285G, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Zhongzhen Yang, Marion Arnoux, Damien Hazelard, Owen R. Hughes, Joe Nabarro, Adrian C. Whitwood, Martin A. Fascione, Christopher D. Spicer, Philippe Compain, William P. UnsworthNew Successive Ring Expansion (SuRE) protocols are described for use on unreactive lactams, as well as iminosugar derived lactams.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for A phosphamide nucleotide analog: a substrate for polymerase synthesis of DNA By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,2963-2967DOI: 10.1039/D4OB00089G, CommunicationJiong Meng, Qiaqia Guo, Xiaona Zhai, Song Yang, Shuai Wang, Pengcheng Wang, Debin JiA phosphamide nucleotide analog (dNTPγNH2) exhibited higher stability than dNTPs and can be recognized by DNA polymerases in PCR.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for A pyridine-N-oxide catenane for cation recognition By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,3001-3008DOI: 10.1039/D4OB00176A, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sean R. Barlow, Nathan R. Halcovitch, Nicholas H. EvansA pyridine-N-oxide containing [2]catenane may be reversibly protonated, as well as bind lithium cations more strongly than sodium cations.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Stereoselective synthesis of (R)- and (S)-1,2-diazetidine-3-carboxylic acid derivatives for peptidomimetics By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,2974-2977DOI: 10.1039/D4OB00278D, Communication Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Matthew Nutter, Henry Stone, Michael Shipman, Stefan RoesnerStereoselective synthesis of both enantiomers of orthogonally protected 1,2-diazetidine-3-carboxylic acid (aAze) from homochiral glycidol and its application in peptidomimetics.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Selective enhancement of (6–4) photoproduct formation in dithymine dinucleotides driven by specific sugar puckering By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,3025-3034DOI: 10.1039/D4OB00279B, PaperJouda Jakhlal, Clément Denhez, Stéphanie Coantic-Castex, Agathe Martinez, Dominique Harakat, Thierry Douki, Dominique Guillaume, Pascale ClivioEvidence is presented that (6–4) photoproduct formation between two thymine residues in dinucleotide analogues is significantly and specifically enhanced when the 5''- and 3''-end sugar puckering are mainly north and south, respectively.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Charge-transfer inclusion complex formation of the tropylium cation with prism[6]arenes By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00423J, CommunicationGuojiao Zhang, Channi Cheng, Zhengxiang Li, Dezhi Zhao, Chengyou HanWe report that charge-transfer (CT) inclusion complexes were formed between prism[6]arenes and tropylium cation. Additionally, the CT complex showed Cl−/Ag+ responsiveness which can be easily monitored by the naked eye.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Electro-oxidative three-component cascade coupling of isocyanides with elemental sulfur and amines for the synthesis of 2-aminobenzothiazoles By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00432A, PaperPeng-Fei Huang, Jia-Le Fu, Ying Peng, Jian-Hong Fan, Long-Jin Zhong, Kewen Tang, Yu Liu2-Aminobenzothiazoles are commonly encountered in various functional compounds. Herein, we disclose an electro-oxidative three-component reaction for the effective synthesis of 2-aminobenzothiazoles under mild conditions, utilizing non-toxic and abundant elemental sulfur...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for An FeCl3-catalyzed three-component reaction for the synthesis of β-(1,2,3-triazolyl)-ketones using DMF as a one-carbon source By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00207E, CommunicationRuilin Fang, Lei Zheng, Xuyang Chen, Can Wang, Yunfeng ChenFeCl3-catalyzed oxidative condensation of NH-1,2,3-triazoles and aryl methyl ketones and DMF has been reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Measuring local pH at interfaces from molecular tumbling: A concept for designing EPR-active pH-sensitive labels and probes By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00167B, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Maxim A. Voinov, Nicholas Nunn, Roshan Rana, Atli Davidsson, Alex I. Smirnov, Tatyana I. SmirnovaEPR-based local pH measurements based on changes in rotational dynamics of spin-bearing molecules upon protonation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for New Generation of Highly Reactive Allylborating Agents For Cu(I)-Catalyzed Allylation of Chiral Sulfinylimines By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00291A, PaperMichael S. Alexeev, Tatyana V. Strelkova, Michail M. Ilyin, Jr., Yulia V. Nelyubina, Ivan A. Bespalov, Michael Medvedev, Victor N Khrustalev, Nikolai KuznetsovThe implementation of selective catalytic processes with highly active reagents is an attractive strategy that meets modern principles of sustainable development of chemistry. In the current study, we for the...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Tetrabutylammonium decatungstate (TBADT), a compelling and trailblazing catalyst for visible-light-induced organic photocatalysis By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00171K, Review ArticleBor-Cherng Hong, Ranadheer Reddy IndurmuddamThis review summarizes recent developments in visible-light or near-visible-light photocatalysis reactions enabled by the TBADT catalyst.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Built-in Browser Support for Responsive Images By www.html5rocks.com Published On :: Thu, 11 Sep 2014 00:00:00 +0000 Take advantage of the new element and new features of in your next responsive website. Full Article
for Wanted: A booster dose for airlines By www.thehindubusinessline.com Published On :: Sun, 27 Jun 2021 12:55:40 +0530 As vaccination numbers increase, airlines and the government look for the middle path to revive the beleagured travel sector Full Article Flight Plan
for A lift for MRO By www.thehindubusinessline.com Published On :: Sun, 27 Jun 2021 13:02:54 +0530 It is time to help Indian aviation’s technical side realise its potential Full Article Flight Plan
for Year-end blues for beleagued airlines By www.thehindubusinessline.com Published On :: Sun, 11 Jul 2021 19:18:23 +0530 The results of IndiGo and SpiceJet hold clues to the mid-term future of the country’s airline industry Full Article Logistics
for Reskilling of airline workforce needed By www.thehindubusinessline.com Published On :: Sun, 28 Nov 2021 18:14:11 +0530 Industry grapples with skilling/reskilling employees right from pilots to ground handling staff whose skills may be redundant Full Article Flight Plan
for A380: How Airbus forecast misfired By www.thehindubusinessline.com Published On :: Sun, 26 Dec 2021 18:20:55 +0530 Sinks $25 billion in the process Full Article Flight Plan
for 2022 holds promise for the airline sector By www.thehindubusinessline.com Published On :: Sun, 09 Jan 2022 17:48:23 +0530 Omicron might dent growth, but the long-term outlook seems promising Full Article Flight Plan
for Demand for more flight schools soars By www.thehindubusinessline.com Published On :: Sun, 09 Jan 2022 17:52:09 +0530 Pilot shortage is hurting airline operations in India, with the industry expected to need at least 1,000 to 1,500 pilots every year Full Article Flight Plan
for Next order of business for Tata Sons By www.thehindubusinessline.com Published On :: Sun, 06 Feb 2022 16:53:48 +0530 How will Tata Sons turn around all the airlines under its fold, except maybe the Kochi-based Air India Express? Full Article Flight Plan
for Another tough year for airlines By www.thehindubusinessline.com Published On :: Sun, 06 Mar 2022 22:00:00 +0530 Ukraine-Russia conflict to result in the steep escalation of aircraft leasing charges Full Article Flight Plan
for First-ever gravity-defying plane swap set for April 24 By www.thehindubusinessline.com Published On :: Sun, 17 Apr 2022 20:02:19 +0530 Two pilots will swap planes mid-air Full Article Flight Plan
for Electric aircraft set to transform urban mobility By www.thehindubusinessline.com Published On :: Sun, 15 May 2022 19:20:02 +0530 Investors are pouring in billions of dollars into eVTOL project (electric vertical take offs and landing aircraft) to ferry passengers Full Article Flight Plan
for Yoke vs. sidestick: Jury still out on what works best for pilots By www.thehindubusinessline.com Published On :: Sun, 24 Jul 2022 21:00:00 +0530 Why do Airbus commercial aircraft have sidesticks and Boeing have yokes as control units? Full Article Logistics
for Airlines’ performance metrics may need an overhaul By www.thehindubusinessline.com Published On :: Sun, 04 Sep 2022 22:00:00 +0530 It may be time to revisit RASK, CASK metrics; benchmarking based on cost drivers can boost an airline’s performance Full Article Flight Plan
for Youtube introduces shopping affiliate programme for eligible Indian creators via Flipkart and Myntra By www.thehindu.com Published On :: Fri, 25 Oct 2024 12:38:20 +0530 As more platforms allow creators to earn from viewers’ purchases of featured products, YouTube also announced its Shopping affiliate programme in India Full Article Technology
for Sarvam AI launches Sarvam 1 for Indic languages By www.thehindu.com Published On :: Mon, 28 Oct 2024 14:47:54 +0530 The custom training corpus, Sarvam-2T comprised of 20 percent datasets in Hindi as well as English and programming languages so the AI model can perform multilingual tasks Full Article Technology
for Hong Kong unveils responsible AI framework for financial sector By www.thehindu.com Published On :: Mon, 28 Oct 2024 15:20:41 +0530 Hong Kong’s responsible AI framework comes amid increasing international competition and tensions affecting access to AI technology Full Article Technology
for Meta builds AI search engine to cut Google, Bing reliance, the Information reports By www.thehindu.com Published On :: Tue, 29 Oct 2024 10:00:06 +0530 The Facebook-owner currently relies on Google and Bing search engines to give users answers on news, stocks and sports Full Article Technology
for Jio’s Diwali Dhamaka plan offers year-long prepaid plan for ₹3,599 By www.thehindu.com Published On :: Tue, 29 Oct 2024 13:14:07 +0530 Jio is offering a prepaid plan of 2.5 GB of data per day for an entire year, priced at₹3,599, as part of a Diwali offer Full Article Technology
for GitHub unveils multi-model Copilot, Spark for AI developers By www.thehindu.com Published On :: Tue, 29 Oct 2024 21:50:00 +0530 Anthropic’s Claude 3.5 Sonnet will be available via GitHub Copilot starting today and Google’s Gemini 1.5 Pro will be available in the coming weeks Full Article Technology
for Crypto firm Consensys to cut 20% of workforce amid macroeconomic, regulatory headwinds By www.thehindu.com Published On :: Wed, 30 Oct 2024 11:42:41 +0530 The crypto firm added that elevated interest rates, inflationary pressures, and tightening liquidity have created a more “cautious macroeconomic environment” Full Article Technology
for Chinese researchers develop AI model for military use on back of Meta's Llama By www.thehindu.com Published On :: Fri, 01 Nov 2024 09:59:35 +0530 ChatBIT was fine-tuned and "optimised for dialogue and question-answering tasks in the military field", the paper said Full Article Technology
for Dropbox to lay off 20% of its workforce By www.thehindu.com Published On :: Fri, 01 Nov 2024 14:10:37 +0530 Last year in April, Dropbox fired 16% of the workforce for similar reasons due to a decrease in cloud growth and spent money in hiring AI specialists instead Full Article Technology
for Transformation Stories #4 A New Podcast Interview With Me (Rob Larsen) By htmlcssjavascript.com Published On :: Wed, 28 Feb 2024 18:33:05 +0000 Check out yours truly on an episode of Atlas Systems’ Transformation Stories. A hands-on leader and change-maker with 20 years of experience, Rob Larsen remains at the forefront of software-led innovation – in financial services and the larger enterprise world. In this all-new conversation with Atlas Systems, Larsen offers insights into finding the right pace […] Full Article CSS HTML Web
for WHO to evacuate 1,000 Gazan women, children for urgent medical care By www.thehindu.com Published On :: Mon, 21 Oct 2024 16:02:57 +0530 Last week, U.N. investigators said Israel was deliberately targeting health facilities in Gaza, and killing and torturing medical personnel there, accusing the country of "crimes against humanity". Full Article Health
for Centre eyes ‘presumed consent’ for cornea retrieval in hospital deaths By www.thehindu.com Published On :: Tue, 22 Oct 2024 23:24:42 +0530 THOTA may be amended to facilitate retrieval of cornea from all Indians who die in hospitals, without family consent. Full Article India
for Are cats good for our health? By www.thehindu.com Published On :: Wed, 23 Oct 2024 17:16:18 +0530 Living with a cat can have a profound – and sometimes surprising – effect on our physical and mental health. Still, living with cats is not without risks Full Article Health
for For type 2 diabetes, focusing on when you eat – not what – can help control blood sugar By www.thehindu.com Published On :: Fri, 25 Oct 2024 16:07:10 +0530 Time-restricted eating, also known as the 16:8 diet, became popular for weight loss around 2015. Studies have since shown it is also an effective way for people with type 2 diabetes to manage blood glucose Full Article Health
for Covid lessons learned? U.N. summit mulls plan for healthy planet, and humans By www.thehindu.com Published On :: Sat, 26 Oct 2024 16:41:39 +0530 At the U.N. summit in Cali, delegates are working on a “biodiversity and health action plan” proposed for adoption by the 196 member nations of the Convention on Biological Diversity Full Article Health
for 30,000 critical care beds, regional centres for National Institute of Virology are among plans under PM-ABHIM: V.K. Paul By www.thehindu.com Published On :: Sat, 26 Oct 2024 16:44:34 +0530 Expanding healthcare infrastructure plans also include integrated public health units in 600 districts and 30 branches of the National Centre for Disease Control, Niti Aayog member Dr. Paul has said Full Article Health
for What is stereotactic radiation therapy for prostate cancer? How does it compare to other treatments? By www.thehindu.com Published On :: Mon, 28 Oct 2024 17:06:09 +0530 Stereotactic radiotherapy uses high doses of radiation to target and kill cancer cells; it uses newer machines that can deliver very focused radiation beams Full Article Health
