on Asymmetric [3 + 2] cycloaddition of donor–acceptor cyclopropanes with azadienes enabled by Brønsted base catalysis By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00002A, Research ArticleShu Li, Zhi-Hong Dong, Si-Yu Dan, Mei-Jun Zheng, Teng Long, Jie Zhan, Qing Zhou, Wen-Dao Chu, Quan-Zhong LiuA chiral bifunctional Brønsted base-catalyzed enantioselective [3 + 2] cycloaddition of D–A cyclopropanes and azadienes is reported. The protocol features broad substrate scope, mild reaction conditions and high functional group tolerance.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Organocatalytic formal [4 + 2] cycloaddition of o-quinone-methyl derivatives and 2-isocyanatomalonate diesters for the construction of chroman derivatives with adjacent quaternary chiral centers By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00141A, Research ArticleTong Xiong, Yi-Zhao Xu, Yao Wang, You-Cai Xiao, Fen-Er ChenAn asymmetric organocatalytic formal [4 + 2] cycloaddition/annulation cascade of ortho-quinone methides with 2-isocyanatomalonate diesters has been reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Stereodivergent synthesis of chiral spiropyrazolones through Pd-catalyzed asymmetric sequential hydroalkylation of 1,3-enynes: unusual solvent effects on the enantioselectivity By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00358F, Research ArticleShan Wang, Long Li, Yifei Zheng, Luqing Li, Yingcheng Wang, Fangzhi Peng, Zhihui ShaoChiral spiropyrazolones were constructed through Pd-catalyzed asymmetric sequential hydroalkylation of 1,3-enynes. Four stereoisomers could be obtained through substrate control and chiral ligand control.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Vaska's complex–PMHS combination enabled mild and chemoselective reduction of sulfoxides to sulfides with low catalyst loading By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00312H, Research ArticleFang-Fang Xu, Zhong-Lei Ruan, Pei-Qiang HuangWe report a highly efficient, versatile, and chemoselective method for the catalytic reduction of sulfoxides to sulfides under mild conditions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Decarbonylative C(sp2)–C(sp2) reductive cross-coupling of aroyl fluorides with aryl bromides by palladium/cobalt co-catalysis By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00305E, Research ArticleChen He, Zhiyong Song, Wei Yao, Rui Lin, Yuanhong MaHerein, we report a decarbonylative C(sp2)–C(sp2) reductive cross-coupling of aroyl fluorides with aryl bromides by palladium and cobalt co-catalysis.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Blue light-mediated carbene transfer reaction of thioesters with diazoesters: efficient synthesis of tetrasubstituted Z-enol esters By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00265B, Research ArticleShuncheng Wang, Hua Zhang, Jin Yang, Dongfang Zhang, Xin-Ping HuiAn efficient metal-free, blue light-mediated carbene transfer reaction of thioesters with diazoesters has been achieved. This protocol produced tetrasubstituted Z-enol esters containing arylsulfur groups in good yields under mild conditions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Triazatriangulenium salts – hosts and guests in supramolecular assemblies in solution By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00500G, Research Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sayan Sarkar, Michael Böck, Agnes Uhl, Aleksandr Agafontsev, Jürgen Schatz, Evgeny A. KataevSelf-assembly of triangulenium dyes bearing C3-C8 substituents and their interaction with aromatic compounds and cyclophanes were studied in solution.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Cyclization reactions of 1,6-dienes and 1,6-enynes by dual cobalt photocatalysis By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00311J, Research ArticlePei-Ting Li, Zi-Fa Shi, Wei YuTwo triphenylamine-derived organophotocatalysts were developed. Their photocatalytic capacity was exploited to enable the [CoIII]-H-mediated cycloisomerization of 1,6-dienes and reductive cyclization of 1,6-enynes under visible light irradiation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Iodine-catalyzed intermolecular 1,2-thio (seleno)amination of alkenes with 1,2,3-triazoles and disulfides (diselenides) in air By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00246F, Research ArticleJian Ji, Xuwen Chen, Zongjing Hu, Cong Guan, Jinhua Liu, Yaqi Deng, Shunying LiuIodine-catalyzed 1,2-thio (seleno)amination of alkenes via direct N- and C-centered radical cross-coupling was established to elicit highly regioselective β-triazolized thioalkyl compounds.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Nickel metallaphotoredox-catalyzed C–O bond activation/Csp2–Csp3 coupling enabled by phosphine By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00310A, Research ArticleJiaxi Fang, Ziheng Jian, Huan Liu, Yuting Wang, Xianbo Yu, Zehuai Mou, Huifei WangA novel and general nickel/photoredox dual catalysis platform for benzyl alcohol C–O bond activation/Csp2–Csp3 cross coupling of benzothiazolyl bromide and free alcohol, enabled by the catalytic generation of an alkyl radical, is reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Spiro-centre substitution effects in the intramolecular spin–spin interactions of spirobiacridine diradicals By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00419A, Research Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Shinichi Ogawa, Takuya Kanetomo, Masaya EnomotoSpirodiradicals with the Si and Ge spiro atoms exhibit a S = 1 state. The magnetic interaction in the Si derivative was found to be lower than that in the Ge derivative, implying a negative effect on σ*(Si–Cα)–π* hyperconjugation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Three-component Friedel–Crafts-type difunctionalization of ynamides with (hetero)arenes and iodine(III) electrophile By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00489B, Research Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jun Kikuchi, Toya Nagata, Shingo Ito, Naohiko YoshikaiA three-component Friedel–Crafts type difunctionalization of ynamides with an iodine(III) electrophile and electron-rich (hetero)arenes has been developed, enabling regio- and stereoselective synthesis of densely functionalized enamides.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Metal-Free Cascade O-H Double Insertion Between I(III)/S(VI)-Ylides, Carboxylic Acids, and Alcohols: Modular Access to Unsymmetrical α,α-O,O-Substituted Ketones By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00453A, Research ArticleShang-Shi Zhang, Jiaohang Wei, Wen-Xuan Zou, Qiong Hu, Mei-Zhu Bao, Dan-Ting Shen, Lin Xiao, Jia-Lin Song, Xiang LiuThe synthesis of unsymmetrical α,α-O,O-substituted ketones via O-H double insertion is appealing but remains constrained due to the lack of compatible coupling partners or uncontrollable selectivity. Herein, we present a...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Correction: Stereodivergent and enantioselective total syntheses of isochaetominines A–C and four pairs of isochaetominine C enantiomers: a six-step approach By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO90034K, Correction Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Zhong-Yi Mao, Hui Geng, Tian-Tian Zhang, Yuan-Ping Ruan, Jian-Liang Ye, Pei-Qiang HuangTo cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Visible-light-mediated catalyst-free synthesis of trifluoromethyl(spiro)-epoxides bearing contiguous quaternary centers By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00184B, Research ArticleJingchuan Lin, Yu Zhang, Jinxin Wang, Xinyu Han, Shenglan Zhu, Tong Li, Yanping Zhu, Wei-Dong ZhangHerein, we describe a non-covalent complex-mediated epoxidation strategy that can yield highly selective central spiro-epoxides by irradiation with visible light without the need for catalyst addition.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Base-induced azofluoroalkylation of unactivated alkenes via halogen atom transfer By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2161-2170DOI: 10.1039/D3QO02114A, Research ArticleJing Zhang, Yanchuang Zhao, Yu-Yi Zhu, Peng Lei, Hanru Liu, Chang-Sheng Wang, Shuya Xing, Yong Liu, Shao-Fei Ni, Thomas Castanheiro, Li-Wen Xu, Xinxin ShaoA base-induced three-components coupling employing unactivated alkenes, fluoroalkyl iodides and diazonium salts under mild reaction conditions has been developed.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Sulfamide instead of urea in Biginelli reaction: from black box to reality By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2155-2160DOI: 10.1039/D3QO01926H, Research ArticleAlexander Yu. Lyapunov, Andriy V. Tarnovskiy, Sergey Yu. Boron, Eduard B. Rusanov, Galyna P. Grabchuk, Dmytro M. Volochnyuk, Serhiy V. RyabukhinThe scope and limitations of the classical Biginelli reaction have been expanded to principally novel substrates: sulfamide and its monosubstituted analogues.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Unprecedented single-electron-transfer reduction-based N → C acyl migration reactions of imides enabled by redox-neutral photocatalysis By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2344-2350DOI: 10.1039/D3QO01955A, Research ArticleLinge Huai, Li Zhang, Zhentao Wang, Yewen FangN → C acyl migration: in the absence of a base, redox-neutral photocatalyzed acyl migration reactions have been realized via the reaction of N-vinylimides with alkyl radicals derived from alkyl silicates.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Stereoselective skeletal modification of tryptanthrins to install chiral piperidine-2-ones enabled by Brønsted acid catalysis By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2171-2177DOI: 10.1039/D3QO02029K, Research ArticleRong Zeng, Xiang Zhang, Yuan-Yuan Lei, Zhuo-Zhuo Zhang, Min Jiang, Qing-Zhu Li, Jun-Long Li, Bo HanAn asymmetric formal [4 + 2] cyclisation between azlactones and aza-dienes derived from simple tryptanthrins has been developed. With this established protocol, yielding a series of novel piperidine-2-one-fused tryptanthrins with up to >99 : 1 er under mild conditions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Iron(III)/quinoxaline-derived N,N-ligand catalyzed oxygen transfer reaction of N-vinyl nitrones through selective 4π-electrocyclization and N–O bond cleavage By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2277-2282DOI: 10.1039/D3QO01999C, Research ArticleYan-Jiao Lu, Feng-Lan Lu, Jin-Qi Zhang, Chun-Hua Chen, Cui Liang, Xiao-Pan Ma, Dong-Liang MoWe describe an iron(III)/quinoxaline-derived N,N-ligand promoted O-transfer reaction of N-vinyl nitrones through selective O-4π-electrocyclization and N–O bond cleavage to prepare a variety of 2,5-dihydrooxazoles in good yields.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Synthesis of benzothiophenes via sulfonium-[3,3]-rearrangement of aryl sulfoxides with allenenitriles By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2208-2214DOI: 10.1039/D4QO00121D, Research ArticleLei Zhang, Kun Wan, Huanhuan Wang, Mengyao Wang, Ao Cui, Xin Huang, Bo PengA facile synthesis of benzothiophenes from readily available aryl sulfoxides and allenenitriles has been established through sulfonium-rearrangement triggered cyclization.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Dynamic kinetic resolution of α-F-β-ketone amides (esters) via Ir/f-diaphos-catalyzed asymmetric hydrogenation By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2201-2207DOI: 10.1039/D4QO00125G, Research ArticlePengtao Yang, Dingguo Song, Lingxin Chen, Xianghua Zhao, Yirui Chen, Feiyang Shen, Fei Ling, Weihui ZhongHighly reactive and highly stereoselective asymmetric hydrogenation of α-F-β-ketone amides (esters) via Ir/f-diaphos-catalyzed dynamic kinetic resolution is reported.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Deoxygenation of N-heterocyclic N-oxides using isopropanol as a recyclable reductant By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2249-2268DOI: 10.1039/D4QO00208C, Research ArticleHo Kyeong Ryu, Yun Do Song, Jun Hee LeeAn organic photoredox-based recyclable strategy that facilitates the chemoselective deoxygenation of various functionalised N-heterocyclic N-oxides is presented.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on A formal (3 + 2) annulation–Cannizzaro cascade of bifunctional peroxides for the synthesis of dihydrofurans By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2215-2219DOI: 10.1039/D4QO00215F, Research ArticleYiwei Chen, Min Gao, Qianlan Xu, Jiumeng Zhang, Lin HuTunable tandem processes of bifunctional peroxides allow the divergent construction of functionalized dihydrofurans and epoxides by simply changing the basic conditions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Synthesis of enantiopure 1,2,3-triazolylidene-type mesoionic carbene (MIC) conjugate acids featuring a rigid bicyclic scaffold By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2178-2181DOI: 10.1039/D4QO00269E, Research ArticleVojtěch Dočekal, Mohand Melaimi, Simona Petrželová, Jan Veselý, Xiaoyu Yan, Guy BertrandChiral NHCs have found numerous applications as ligands for transition metals and in their own right for asymmetric catalysis. We report a synthetic route from L-malic acid to enantiopure 1,2,3-triazoliums with the chiral center in a fused ring.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Iridium-catalyzed reductive γ-lactonization of ortho-acylbenzoic acids in water: sustainable access to phthalides By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2220-2230DOI: 10.1039/D3QO02019C, Research ArticleYang Chen, Jingyu Zhang, Hongguang Du, Renshi Luo, Jiaxi Xu, Zhanhui YangIridium-catalyzed reductive γ-lactonization of ortho-acylbenzoic acids in water provides a practical and sustainable route to phthalides.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Rhodium-catalyzed C–C bond alkenylation and arylation of α-branched N-sulfonyl amines By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2182-2188DOI: 10.1039/D3QO02140H, Research ArticleLun Xu, Yucheng Liu, Hang Shi, Lun LiIn this work, we described a rhodium-catalyzed C–C bond cleavage of α-branched amines via β-carbon elimination, then formed a five-membered rhodacycle intermediate, which can be captured by styrene(alkenylation) or silane(arylation).The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Visible light/copper catalysis enabled Heck-like coupling between alkenes and cyclic sulfonium salts via selective C–S bond cleavage By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2195-2200DOI: 10.1039/D3QO02009F, Research ArticleXianqin Liu, Xufeng Li, Linyuan Wang, Yongjia Shi, Jian Lv, Daoshan YangA Heck-like coupling of cyclic sulfonium salts with alkenes via selective C–S bond cleavage using a copper complex as a photosensitizer through a visible-light-driven redox-neutral process has been developed.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Electrode-switchable: exploring this new strategy to achieve regiodivergent azidoiodination of alkenes By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2189-2194DOI: 10.1039/D3QO01935G, Research ArticleXin-Lei Sun, Chen-Xi Xia, Yue Ren, Yu-Jin Li, Zhi-Qian Cao, Ling-Guo MengAn “electrode-switchable” organic electrochemistry method for the azidoiodination of alkenes, where the choice of anode dictates the regiodivergent alkene azidoiodination, reveals a novel pathway for controlled regioisomers.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Selective photochemical synthesis of primary arylamines and symmetric diarylamines via amination of aryl bromides using Ni(NH3)6Cl2 as a nitrogen source and catalyst By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2313-2318DOI: 10.1039/D4QO00116H, Research ArticleZhehui Xu, Jianyang Dong, Geyang Song, Fuqiang Kong, Gang Li, Dong XueThe selective synthesis of primary arylamines and diarylamines via coupling reactions with ammonia as a nitrogen source is still challenging.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Photo-induced catalyst-free formal carbon insertion of acylsilanes into B–B and B–Si bonds By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2339-2343DOI: 10.1039/D4QO00139G, Research ArticleXiongxiong Lu, Qingbin Zhao, Hao Zhang, Pan Xu, Xuenian Chen, Zhenxing LiuA formal carbon insertion of acylsilanes into B–B and B–Si bonds has been developed. The in situ formed siloxycarbene under blue LED irradiation worked as the intermediate for the reaction. When 2-furyl and 2-thiophenyl acylsilanes were used, the B(pin) ring was enlarged to a six-membered ring.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Origin of site-selectivity of hydrogen atom transfer in carbohydrate C–H alkylations via photoredox catalysis By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2269-2276DOI: 10.1039/D4QO00073K, Research ArticleYujie Ji, Lingfei Hu, Han Gao, Yan-Bo Wu, Xiangying Lv, Gang LuTwo major factors, i.e., C–H σ orbital energy and C–H BDE, account for the HAT site-selectivity of carbohydrates with the quinuclidine radical cation.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Electron donor–acceptor complex photoactivation for deaminative alkynylation, alkenylation and allenylation: a comprehensive study By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2231-2240DOI: 10.1039/D4QO00177J, Research ArticleRomain Lapierre, Lina Truong, Matthieu Hedouin, Hassan Oulyadi, Bruno Schiavi, Alexandre Jean, Philippe Jubault, Thomas PoissonHerein, we disclose our study toward photoinduced deaminative alkynylation, alkenylation and allenylation.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Fe-catalyzed B–H and Si–H insertion reactions of gem-dihaloalkanes By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2241-2248DOI: 10.1039/D4QO00136B, Research ArticleXinyu Wang, Zhaobin WangWe present an approach involving Fe-catalyzed B–H and Si–H insertion of gem-dichloroalkanes. In contrast to previous strategies, our method uses gem-dihaloalkanes as non-stabilized carbene precursors and operates through a radical reaction pathway.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on A dearomatization–rearomatization strategy for construction of 4H-quinolizin-4-ones via C–H bond functionalization of pyridines By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2319-2325DOI: 10.1039/D3QO01990J, Research ArticleDong Qiu, Yijin SuHerein, the synthesis of 4H-quinolizin-4-ones from N-(2-methoxy-2-oxoethyl) pyridinium salts and alkenes through dearomative cycloaddition and rearomative ring expansion has been developed.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Regioselective electrochemical cascade C–H sulfonylation–bromination of indolizines to access difunctionalized indolizines By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2306-2312DOI: 10.1039/D4QO00035H, Research ArticleWenxuan Jiang, Xiang Liu, Chuanying Zhu, Meiyi Chen, Weidan Li, Hua CaoRegioselective electrochemical C–H sulfonylation–bromination between indolizines, sodium sulfinates, and KBr has been established in an undivided cell, in which KBr serves as both the brominating agent and electrolyte.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Electrochemical remote C(sp3)–H thiocyanation By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2283-2288DOI: 10.1039/D4QO00032C, Research ArticleXinyu Pang, Hui He, Xiangrui Meng, Linbao Zhang, Shaofei Ni, Ming Li, Weisi GuoAn electrochemical thiocyanation of distal C(sp3)–H bonds based on amidyl radical-mediated 1,5-HAT has been developed. The transformation is highly site-selective and compatible with primary, secondary, and tertiary sulfonamides, and bioactive derivatives.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Photoinduced alkylation of pyrazolones via β-scission of unstrained aliphatic alcohol derivatives By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2289-2296DOI: 10.1039/D4QO00077C, Research ArticleXinxin Geng, Pan Tao, Yujun Li, Ke ZhengAn efficient radical approach was reported for the transformation of unstrained aliphatic alcohols through the β-scission of alkoxyl radicals.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Nickel/photoredox-catalyzed carbonylative transformations of α-phosphorus-, α-sulfur-, and α-boron-substituted alkyl halides By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2297-2305DOI: 10.1039/D4QO00167B, Research Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Le-Cheng Wang, Xiao-Feng WuA novel dual nickel/photoredox catalyzed direct amino- and alkoxycarbonylation of α-heteroatom substituted organohalides has been developed.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Prins cyclization of 1,3-dioxinone: synthesis of 11-epi-badkhysin By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2332-2338DOI: 10.1039/D4QO00162A, Research ArticleXiaoliang Xu, Ping Hua, Yiren Xu, Baoqing He, Jingfeng Zhao, Liang Li, Wen Chen, Hongbin ZhangThe asymmetric synthesis of highly functional 11-epi-badkhysin has been accomplished using a structure-unit based approach.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Palladium-catalyzed asymmetric [4 + 3] cycloaddition of acyclic α,β-unsaturated imines with trimethylenemethane donors: access to chiral non-fused azepines By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2326-2331DOI: 10.1039/D4QO00064A, Research ArticleTing-Peng Li, Shuixiu Su, Jia-Huan Shen, Meng Zang, Yang-Zi Liu, Quannan Wang, Wei-Ping DengAn efficient approach for the construction of non-fused azepines in good yields with high enantioselectivity via Pd-catalyzed asymmetric [4 + 3] cycloaddition was developed.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Advancement in the C–H bond alkylation of (hetero)arenes catalyzed by the most abundant transition metal–iron By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2397-2417DOI: 10.1039/D4QO00063C, Review ArticleChandini Pradhan, Benudhar PunjiAdvancement in the direct C–H bond alkylation of arenes and heteroarenes using the catalysts based on the most abundant transition metal, iron, is summarized.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Catalytic intermolecular hydrofunctionalizations of ynamides By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2351-2374DOI: 10.1039/D4QO00301B, Review ArticleYing-Ying Zhao, Yu-Jing Jia, Yan-Cheng HuThis review carefully summarizes the advances achieved in catalytic hydrofunctionalization of ynamides and is categorized by the bond formation type including C−C, C−X, C−O, C−N, C−S, C−P, C−Si, and C−Ge bonds.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Contributors to the Organic Chemistry Frontiers Emerging Investigator Series 2022–2023 By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2149-2154DOI: 10.1039/D4QO90025A, ProfileThis profile article showcases researchers who have contributed an article to the Organic Chemistry Frontiers Emerging Investigator Series.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Correction: Cu-catalyzed arylation of S-tosyl peptides with arylboronic acids By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2418-2418DOI: 10.1039/D4QO90029D, Correction Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Junjie Ying, Jingrong Huang, Chenguang Liu, Fa-Jie Chen, Chunfa Xu, Fen-Er ChenThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on NHC and photoredox catalysis dual-catalyzed 1,4-mono-/di-fluoromethylative acylation of 1,3-enynes By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00372A, Research ArticleJiuli Xia, Ruiyang Ma, Lihong Wang, Jiaqiong Sun, Guangfan Zheng, Qian ZhangNHC and photocatalysis dual-catalyzed mono/difluoromethylative acylation of 1,3-enynes was realized, providing fluormethyl-substituted allenyl ketones. SO2 might play a critical role in achieving high reactivity and selectivity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Assembly of ionic supramolecular polymers using a decacationic pillar[5]arene to noncovalently crosslink hyaluronic acid for short DNA delivery By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00447G, Research ArticleQian Li, Danying Ma, Yue-Yang Liu, Hui Wang, Wei Zhou, Dan-Wei Zhang, Zhan-Ting LiA multicationic pillar[5]arene noncovalently crosslinks hyaluronic acid to afford ionic supramolecular polymers for intramolecular delivery of short DNA.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Selective deletion of one carbon atom from C60 through benzylamine mediated reactions By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00449C, Research ArticleYaqiong Wang, Yiran Wu, Yuming Yu, Jie Su, Yi Qiu, Liangbing GanBenzylamine selectively adds to one of the two carbonyl groups on the 9-membered orifice to form an N,O-aminal moiety. Subsequent oxidation and hydrogen atom transfer lead to a decarboxylation process and formation of a nor [59]fullerene derivative.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Aculeatones A and B, epimeric lovastatin derivatives with a 6/6/3-tricyclic carbon skeleton from Aspergillus aculeatus and their chemical transformation By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00351A, Research ArticleFei Liu, Fengqing Wang, Qin Li, Bingbing Dai, Weiguang Sun, Jianguo Li, Chunmei Chen, Yonghui Zhang, Hucheng ZhuLovastatin derivatives aculeatones A–F (1–6) with lipid-lowering activity were isolated from Aspergillus aculeatus. 1 and 2 represent the first examples with a 6/6/3-tricyclic scaffold and the biomimetic formation of 1 was achieved starting from 3.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
on Visible-light Induced [1, 3]-Brook Rearrangements of α-Ketoacylsilanes and Its Subsequent Trapping in a Tandem Annulation with 1, 3, 5-Triazinanes and Azomethine Imines By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00463A, Research ArticleZhong Zhang, Sirui Wu, Yuqiao Zhou, Bao-Lin Li, Siyue Xiao, Xiaohu Zhao, Zhipeng YuAn unusual visible light-induced [1, 3]-Brook rearrangement of α-ketoacylsilanes for cascade cyclization with 1,3,5-triazinanes and C,N-cyclic azomethine imines has been developed under catalyst-free and mild reaction conditions. The strategy offers...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
