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Noninvasive chemical approach controls deep region of the brain in mice

In mice, surgery-free technique inhibits region implicated in memory formation




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BASF is considering a $10 billion investment in China

The German giant may build a new Verbund site in Guangdong, China




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Trump’s tweets prompt Pfizer to postpone drug price hikes

The president deemed the price rollback a victory, but industry watchers say Pfizer could benefit in the long run




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U.S. considers tariffs on more Chinese chemicals

Numerous basic inputs may be hit with a 10% import tax as trade war intensifies




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Three-dimensional COF crystals keep growing

Strategy yields crystals big enough to reveal previously elusive structural details




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Compass Therapeutics debuts with $132 million in funding




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Regulus cuts jobs after oligonucleotide safety setback




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FTC takes Tronox and Cristal to federal court




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Brexit expected to spur emigration of scientists




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U.K. builds center in Scotland for medicine production




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DNA Script gets grant for longer DNA




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Manus Bio raises $19 million to make plant ingredients via fermentation




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Linde, Praxair ready second industrial gas sale




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Peer review shake-up on trial at <i>eLife</i>




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U.S. team heads to International Chemistry Olympiad




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These new textile dyeing methods could make fashion more sustainable

Large and small suppliers vow to help a resource-intensive, cost-sensitive industry change with the times




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Reactions




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A carbon fiber cluster grows in South Carolina

Teijin breaks ground on a $600 million plant in Greenwood as global demand grows for the strong, lightweight material




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Entrepreneur rethinks lithium-ion batteries with an eye toward storing renewable energy

Chemist Amy Prieto of Colorado State University discusses her work to commercialize a safer, more customizable battery




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Changes on tap at U.S. Chemical Safety Board

Chair departs, investigators leave, staff fears changing mission




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A question on ethics




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Targeting immune cells could relieve chronic pain

Study finds macrophages talk to sensory nerves to elicit chronic pain caused by nerve damage




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HotSpot Therapeutics debuts with $45 million to pursue allosteric inhibitors

The company claims its technology will allow it to access previously undruggable targets




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Boron arsenide boasts high thermal conductivity

Semiconductor could help dissipate waste heat in electronics




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Sanofi pays $50 million for Revolution Medicines’ SHP2 inhibitor

The partners expect to begin clinical studies of the compound later this year




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Deadly blast in China highlights uneven enforcement of safety regulations

Facilities where 19 died had not been inspected or approved




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Un patógeno recluta bacterias buenas en la piel para iniciar infecciones

Un estudio hace que los científicos se replanteen cómo se desarrollan las infecciones bacterianas




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Pathogen recruits good bacteria on skin to initiate infections

Study shakes up scientists’ understanding of how bacterial infections develop




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New variant of Parkinson’s protein goes against the grain

Short α-synuclein peptide affects uptake of dopamine rather than forming typical clumps in the brain




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Ex-DuPont staffer steals secrets




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India’s Supreme Court slams lack of action to address Taj Mahal deterioration




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Obituary: Robert Daulton Guthrie




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Verge Genomics raises $32 million for machine learning-backed neuroscience drug discovery




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Letting nanoparticles hitchhike on red blood cells

Particles adsorbed on cells accumulate in the first organ downstream from injection site




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New phosphor for LEDs with deep-red-light emission

Cerium-doped nitride compound may lead to applications in horticultural lighting




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AGC boosts active pharmaceutical ingredient production




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Lanxess will invest $50 million in its bromine business




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AkzoNobel buys Brazilian organic peroxides firm




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BASF donates $7 million for UC Berkeley labs




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Ionic liquids boost gas uptake in MOFs

Postsynthesis modification of common MOF improves its CO2 uptake and selectivity




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Entrepreneurs get in on the ground floor with CBD from hemp

Growing this cousin of marijuana could help boost local farm economies




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Targeting immune cells could relieve chronic pain

Study finds macrophages talk to sensory nerves to elicit chronic pain caused by nerve damage




on

HotSpot Therapeutics debuts with $45 million to pursue allosteric inhibitors

The company claims its technology will allow it to access previously undruggable targets




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Cambrex to acquire dosage-form drug contractor Halo

With purchase, manufacturer of active pharmaceutical ingredients will move downstream into finished drugs




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Paper describing piperlongumine anticancer activity retracted

Some coauthors dissent from withdrawal of report, for which key findings have been independently confirmed




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Shintech will spend $1.5 billion to cement role as largest vinyl producer

The Louisiana project will complement an ethylene cracker the Japanese company is building in the state




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Injections of botulinum conjugate relieves chronic pain in mice

Modified toxin targets and silences nerves that transmit pain, offering a potential nonaddictive alternative to opioids




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Vinyl cation busts some new moves

By tweaking its counter ion, classic carbocation inserts into C-H bonds




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Insect sodium channels visualized with cryo-electron microscopy

Structures of voltage-gated channel with toxins suggest strategies for drug development




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GSK, 23andMe to apply personal genetics to drug discovery

New partnership is part of GSK’s R&D face-lift, which includes an increased focus on immune system targets