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Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

Patrice D. Cani
Jun 1, 2008; 57:1470-1481
Metabolism




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Environmental Triggers and Determinants of Type 1 Diabetes

Mikael Knip
Dec 1, 2005; 54:S125-S136
Section IV: Polygenic Disease and Environment




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Insulin Resistance and Type 2 Diabetes

Roy Taylor
Apr 1, 2012; 61:778-779
Commentary




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Predictors of Postpartum Diabetes in Women With Gestational Diabetes Mellitus

Kristian Löbner
Mar 1, 2006; 55:792-797
Pathophysiology




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PPARA Polymorphism Influences the Cardiovascular Benefit of Fenofibrate in Type 2 Diabetes: Findings From ACCORD-Lipid

Mario Luca Morieri
Apr 1, 2020; 69:771-783
Genetics/Genomes/Proteomics/Metabolomics




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The cGAS-cGAMP-STING Pathway: A Molecular Link Between Immunity and Metabolism

Juli Bai
Jun 1, 2019; 68:1099-1108
Perspectives in Diabetes




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Intense Exercise Has Unique Effects on Both Insulin Release and Its Roles in Glucoregulation: Implications for Diabetes

Errol B. Marliss
Feb 1, 2002; 51:S271-S283
Section 6: Pusatile and Phasic Insulin Release in Normal and Diabetic Men




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A Bivariate Genome-Wide Approach to Metabolic Syndrome: STAMPEED Consortium

Aldi T. Kraja
Apr 1, 2011; 60:1329-1339
Genetics




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Vitamin D Receptor Overexpression in {beta}-Cells Ameliorates Diabetes in Mice

Meritxell Morró
May 1, 2020; 69:927-939
Islet Studies




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Is Sugar Addictive?

George A. Bray
Jul 1, 2016; 65:1797-1799
Commentaries




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The Rise of Childhood Type 1 Diabetes in the 20th Century

Edwin A.M. Gale
Dec 1, 2002; 51:3353-3361
Perspectives in Diabetes




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ACE2 and Diabetes: ACE of ACEs?

Daniel Batlle
Dec 1, 2010; 59:2994-2996
Commentaries




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Effect of a High-Protein, Low-Carbohydrate Diet on Blood Glucose Control in People With Type 2 Diabetes

Mary C. Gannon
Sep 1, 2004; 53:2375-2382
Pathophysiology




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Mechanisms of Pancreatic {beta}-Cell Death in Type 1 and Type 2 Diabetes: Many Differences, Few Similarities

Miriam Cnop
Dec 1, 2005; 54:S97-S107
Section III: Inflammation and beta-Cell Death




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Metabolic Endotoxemia Initiates Obesity and Insulin Resistance

Patrice D. Cani
Jul 1, 2007; 56:1761-1772
Obesity Studies




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One Week of Bed Rest Leads to Substantial Muscle Atrophy and Induces Whole-Body Insulin Resistance in the Absence of Skeletal Muscle Lipid Accumulation

Marlou L. Dirks
Oct 1, 2016; 65:2862-2875
Metabolism




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Protecting the Heart in Obesity: Role of ACE2 and Its Partners

Rhian M. Touyz
Jan 1, 2016; 65:19-21
Commentaries




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Autoantibodies in Diabetes

Catherine Pihoker
Dec 1, 2005; 54:S52-S61
Section II: Type 1-Related Forms of Diabetes




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Low-Grade Systemic Inflammation and the Development of Type 2 Diabetes: The Atherosclerosis Risk in Communities Study

Bruce B. Duncan
Jul 1, 2003; 52:1799-1805
Pathophysiology




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Five Stages of Evolving Beta-Cell Dysfunction During Progression to Diabetes

Gordon C. Weir
Dec 1, 2004; 53:S16-S21
Section I: Insulin Resistance-Beta-Cell Connection in Type 2 Diabetes




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From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

Ralph A. DeFronzo
Apr 1, 2009; 58:773-795
Banting Lecture




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Diabetes in China: Epidemiology and Genetic Risk Factors and Their Clinical Utility in Personalized Medication

Cheng Hu
Jan 1, 2018; 67:3-11
Perspectives in Diabetes




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The Multiple Actions of GLP-1 on the Process of Glucose-Stimulated Insulin Secretion

Patrick E. MacDonald
Dec 1, 2002; 51:S434-S442
Section 5: Beta-Cell Stimulus-Secretion Coupling: Hormonal and Pharmacological Modulators




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The Pathobiology of Diabetic Complications: A Unifying Mechanism

Michael Brownlee
Jun 1, 2005; 54:1615-1625
Banting Lecture 2004




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Latent Autoimmune Diabetes in Adults: Definition, Prevalence, {beta}-Cell Function, and Treatment

Gunnar Stenström
Dec 1, 2005; 54:S68-S72
Section II: Type 1-Related Forms of Diabetes




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Poverty and Obesity in the U.S.

James A. Levine
Nov 1, 2011; 60:2667-2668
Editorials




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A Polymorphism in the Glucocorticoid Receptor Gene, Which Decreases Sensitivity to Glucocorticoids In Vivo, Is Associated With Low Insulin and Cholesterol Levels

Elisabeth F.C. van Rossum
Oct 1, 2002; 51:3128-3134
Genetics




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Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis

Jay S. Skyler
Feb 1, 2017; 66:241-255
Perspectives in Diabetes




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Correction: Mitochondrial and nuclear genomic responses to loss of LRPPRC expression. [Additions and Corrections]

VOLUME 285 (2010) PAGES 13742–13747In Fig. 1E, passage 10, the splicing of a non-adjacent lane from the same immunoblot was not marked. This error has now been corrected and does not affect the results or conclusions of this work.jbc;295/16/5533/F1F1F1Figure 1E.




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Correction: A dual druggable genome-wide siRNA and compound library screening approach identifies modulators of parkin recruitment to mitochondria. [Additions and Corrections]

VOLUME 295 (2020) PAGES 3285–3300An incorrect graph was used in Fig. 5C. This error has now been corrected. Additionally, some of the statistics reported in the legend and text referring to Fig. 5C were incorrect. The F statistics for Fig. 5C should state Fken(3,16) = 7.454, p < 0.01; FCCCP(1,16) = 102.9, p < 0.0001; Finteraction(3,16) = 7.480, p < 0.01. This correction does not affect the results or conclusions of this work.jbc;295/17/5835/F5F1F5Figure 5C.




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Correction: Metabolic fingerprinting for diagnosis of fibromyalgia and other rheumatologic disorders. [Additions and Corrections]

VOLUME 294 (2019) PAGES 2555–2568Due to publisher error, “150 l/mm” was changed to “150 liters/mm” in the second paragraph of the “Vibrational spectroscopy of samples” section under “Experimental Procedures.” The correct phrase should be “150 l/mm.”




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Correction: Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system. [Additions and Corrections]

VOLUME 295 (2020) PAGES 1898–1914Yichen Zhong's name was misspelled. The correct spelling is shown above.




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Correction: Rational design, synthesis, and evaluation of uncharged, &#x201C;smart&#x201D; bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase. [Additions and Corrections]

VOLUME 295 (2020) PAGES 4079–4092There was an error in the abstract. “The pyridinium cation hampers uptake of OPs into the central nervous system (CNS)” should read as “The pyridinium cation hampers uptake into the central nervous system (CNS).”




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Correction: Histone demethylase KDM6B promotes epithelial-mesenchymal transition. [Additions and Corrections]

VOLUME 287 (2012) PAGES 44508–44517In Fig. 1A, the wrong image for the control group was presented. The authors inadvertently cropped the control images in Fig. 1, A and E, from the same raw image. Fig. 1A has now been corrected and does not affect the results or conclusions of the work. The authors sincerely apologize for their mistake during figure preparation and for any inconvenience this may have caused readers.jbc;295/19/6781/F1F1F1Figure 1A.




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Remembering Frank Robinson, Giants skipper

Frank Robinson's tenure as Giants manager was short but significant. He and his teams provided hope and promise when both were in short supply around Candlestick Park.




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Inbox: Are Giants waiting to make big splash?

Do you think the Giants are just waiting around and could go after Bryce Harper for a big splash? Beat reporter Maria Guardado answers this question and more from fans.




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Posey expects to be ready for Opening Day

Buster Posey plans to be on the field when Giants pitchers and catchers begin their first workout at Scottsdale Stadium on Wednesday, and if his rehab from right hip surgery continues to go well, he expects the same for Opening Day.




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Zaidi: 'Mutual interest' between Giants, Harper

Giants president of baseball operations Farhan Zaidi would prefer to stay mum when it comes to his forays into the free-agent market, but he realized there was no use in attempting to obscure the club's meeting with superstar Bryce Harper in Las Vegas earlier this week.




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Giants eager to see Bart during spring camp

It's been less than a year since the Giants selected Joey Bart with the second overall pick in the 2018 MLB Draft, but the 22-year-old catcher is already generating plenty of excitement within the organization.




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Bumgarner not a fan of the opener strategy

Madison Bumgarner has made it known he's not a fan of the "opener," a strategy of utilizing a pitcher -- usually a reliever -- to get the first few outs of a game before bringing in a pitcher who would usually start or pitch long relief.




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Predicting the Giants' Opening Day roster

With Spring Training set to kick off Tuesday, it feels like an opportune time to put together a way-too-early look at who might be with the Giants when they begin their regular season against the Padres on March 28.




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Uniform patch to mark 150 years of pro baseball

All 30 Major League teams will wear special "MLB 150" patches on their uniforms for the entire 2019 season in honor of the 150th anniversary of the 1869 Cincinnati Red Stockings, the first openly all-salaried professional baseball team.




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30 low-key acquisitions who could pay off big

Fans and analysts spend the entire offseason speculating where the top free agents could go, but sometimes an under-the-radar pickup can end up making a world of difference. As positional competitions begin to heat up at Spring Training camps this month, MLB.com's beat writers were asked to identify one potentially overlooked acquisition for each of the 30 clubs. Here's who they came up with.




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Giants open spring camp as work in progress

One year after making a pair of high-profile acquisitions in Andrew McCutchen and Evan Longoria, the Giants have experienced a far slower and quieter winter, leaving the club with quite a few question marks as pitchers and catchers reported to Scottsdale, Ariz., for the start of Spring Training on Tuesday.




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Sources: Giants add Parra to outfield mix

As they continue to await a resolution to the Bryce Harper sweepstakes, the Giants augmented their outfield depth by signing veteran Gerardo Parra to a Minor League deal Tuesday, sources confirmed to MLB.com's Jon Paul Morosi and Mark Feinsand.




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Bumgarner 'would love to stay' with Giants

Despite trade speculation, Madison Bumgarner arrived at Scottsdale Stadium on Tuesday as Giants pitchers and catchers reported for Spring Training. He's still on track to be the club's starter on Opening Day, though his future in San Francisco remains murky as he prepares to enter his final season before free agency.




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Giants acquire righty reliever Gott from Nats

The Giants added another arm into their bullpen mix Wednesday, acquiring right-hander Trevor Gott from the Nationals for cash considerations.




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Bumgarner, Posey welcome Bart to camp

Less than two hours after meeting Madison Bumgarner, top Giants prospect Joey Bart found himself catching one of Bumgarner's bullpen sessions after the veteran left-hander approached him and said, "Let's go on No. 1."




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Prospects who should vie for a roster spot

The 30 prospects below all are getting very long looks this spring with an eye toward breaking camp with the parent club. Even if they start the year in the Minors, they all should get the chance to contribute at some point in the very near future.




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Parra's addition provides veteran OF presence

The Giants have expressed a desire to add multiple veteran outfielders throughout the offseason, and they made their first notable acquisition earlier this week after signing Gerardo Parra to a Minor League contract.