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Synergistic antioxidant capacity of CsNPs and CurNPs against cytotoxicity, genotoxicity and pro-inflammatory mediators induced by hydroxyapatite nanoparticles in male rats

Toxicol. Res., 2019, 8,939-952
DOI: 10.1039/C9TX00221A, Paper
Israa F. Mosa, Mokhtar Youssef, Maher Kamel, Osama F. Mosa, Yasser Helmy
Due to their dynamic characteristics, hydroxyapatite nanoparticles (HAP-NPs) have been employed numerous times in nanomedicine and in tissue engineering, particularly as diagnostic and therapeutic agents.
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Cigarette smoke inhalation aggravates diabetic kidney injury in rats

Toxicol. Res., 2019, 8,964-971
DOI: 10.1039/C9TX00201D, Paper
Songling Jiang, Do Van Quan, Jae Hyuck Sung, Moo-Yeol Lee, Hunjoo Ha
Four weeks of exposure to cigarette smoke aggravated the progression of diabetic kidney injury including inflammation, fibrosis, and oxidative stress.
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Mice with a Sertoli cell-specific knockout of the Ctr1 gene exhibit a reduced sensitivity to cisplatin-induced testicular germ cell apoptosis

Toxicol. Res., 2019, 8,972-978
DOI: 10.1039/C9TX00142E, Paper
Open Access
Rashin Ghaffari, John H. Richburg
Exposure to the chemotherapeutic agent cis-diamminedichloroplatinum(II) (cDDP) is well known to instigate acute and prolonged testicular injury in male patients.
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Effects of moderate red wine on cardiovascular risk factors in diabetics: a systematic review and meta-analysis of randomized controlled trials

Toxicol. Res., 2019, 8,979-987
DOI: 10.1039/C9TX00227H, Paper
Saavia Alice Naame, Decheng Li, Ruixue Huang
Diabetes mellitus is of major public health concerns; its incidence is continuously increasing.
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Methanol extract of Iphiona aucheri ameliorates CCl4 induced hepatic injuries by regulation of genes in rats

Toxicol. Res., 2019, 8,815-832
DOI: 10.1039/C9TX00157C, Paper
Jawaid Ahmed Zai, Muhammad Rashid Khan, Zaib un Nisa Mughal, Riffat Batool, Irum Naz, Sonia Maryam, Zartash Zahra
Alteration in expression of ER stress associated genes, inflammatory genes and antioxidant biochemical induced with CCl4 in liver of rats were restored towards the control rats by co-administration of methanol extract of Iphiona aucheri to rats.
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Astilbin attenuates cerebral ischemia/reperfusion injury by inhibiting the TLR4/MyD88/NF-κB pathway

Toxicol. Res., 2019, 8,1002-1008
DOI: 10.1039/C9TX00222G, Paper
Jing Li, Zhaowei Gu, Yue Liu, Yu Wang, Min Zhao
Ischemic stroke is the second most common cause of death worldwide and cerebral ischemia/reperfusion (I/R) injury also leads to serious tissue damage.
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Astaxanthin reduces perfluorooctanoic acid cytotoxicity in Saccharomyces cerevisiae

Toxicol. Res., 2019, 8,1009-1015
DOI: 10.1039/C9TX00215D, Paper
S. J. Sudharshan, Raghavendra Tirupathi, Madhu Dyavaiah
Perfluorooctanoic acid (PFA) has been identified as an environmental contaminant of high concern for human health.
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Application of the direct peptide reactivity assay (DPRA) to inorganic compounds: a case study of platinum species

Toxicol. Res., 2019, 8,802-814
DOI: 10.1039/C9TX00242A, Paper
Jocelyn D. C. Hemming, Mark Hosford, Martin M. Shafer
The in chemico Direct Peptide Reactivity Assay (DPRA) was developed as a non-animal, relatively high throughput, screening tool for skin sensitization potential.
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Phytochemicals protect L02 cells against hepatotoxicity induced by emodin via the Nrf2 signaling pathway

Toxicol. Res., 2019, 8,1028-1034
DOI: 10.1039/C9TX00220K, Paper
Yan Yan, Kang Wang, Xu Tang, Jun-feng Gao, Bin-yu Wen
Dihydromyricetin (DMY), hyperoside and silybin are phytochemicals that belong to a class called flavonoids, and they have been used in liver protection pharmaceutical preparations, but the specific mechanism of these chemicals is still unclarified.
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Benzoquinone alters the lipid homeostasis in Saccharomyces cerevisiae

Toxicol. Res., 2019, 8,1035-1041
DOI: 10.1039/C9TX00139E, Paper
Abhishek Raj, Vasanthi Nachiappan
BQ exposure inhibited cell growth, increased the ROS-mediated apoptosis, and altered the phospholipids that resulted in membrane proliferation.
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Cytotoxic effect of silica nanoparticles against hepatocellular carcinoma cells through necroptosis induction

Toxicol. Res., 2019, 8,1042-1049
DOI: 10.1039/C9TX00240E, Paper
Yuexiang Niu, Engong Tang, Qingan Zhang
Hepatocellular carcinoma (HCC) is a common cancer that affects people worldwide with high morbidity and mortality, and its resistance to current chemotherapeutic drugs is a serious concern.
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The protective effect of thymoquinone on tert-butylhydroquinone induced cytotoxicity in human umbilical vein endothelial cells

Toxicol. Res., 2019, 8,1050-1056
DOI: 10.1039/C9TX00235A, Paper
Zahra Karimi, Maryam Ghaffari, Jafar Ezzati Nazhad Dolatabadi, Parvin Dehghan
2-tert-Butyl-4-hydroquinone (TBHQ) is used for inhibition of oxidative rancidity in the food industry.
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India's credit profile to face further pressure due to Covid-19: Moody's

Moody's rating on the government of India is Baa2 with negative outlook




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Franklin Templeton issues apology to Sebi for global chief's remarks

Stung by the comments made by the global chief, market regulator on Thursday issued a press release defending the new rules it introduced in October last year




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SC's struggles with 'unruly horse' of public policy in foreign awards

The Nafed-Alimenta judgment shows it might perhaps be time for Parliament to intervene and clarify the notion of public policy in the context of foreign arbitral awards




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US Federal Reserve won't take rates negative, say fund managers, economists

Fed funds futures, which are a gauge of where markets expect the Fed's benchmark overnight lending rate to be, are now pricing in a slightly negative rate environment beginning in December




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Nomura predicts Indian GDP to contract by 5.2% in FY21, more rate cuts

Analysts at Goldman Sachs expect the Indian economy to contract 0.4 per cent in FY21 versus consensus median 2.7 per cent




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Only 13% of industrial units resume ops after Odisha eases lockdown

Micro units in the state have not been able to resume operations to catch up with their larger peers




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Moody's pegs FY21 GDP growth at 0%, says upgrade unlikely in near term

The rapid and widening spread of the Covid-19, deteriorating global economic outlook, falling oil prices, and financial market turmoil are creating a severe and extensive economic and financial shock




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Export contraction in April could surpass March's steep 25-year decline

Major forex earning sectors cite lack of labour, funds and key supplies




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Govt hikes market borrowing limit by over 50% to Rs 12 trillion

The government resorts to market borrowing to make up for the mismatch between its revenue and expenditure.




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Vizag gas leak: NGT orders LG Polymers to deposit Rs 50 cr pending probe

NGT bench set up fact-finding committee, to be headed by former AP High Court judge




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CBDT orders tax officials to not issue scrutiny notices to taxpayers

Move comes after a group of IRS created panic and tax policy uncertainty




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Govt must work to revive consumption, not worry about rating: Rahul Gandhi

Congress wants lockdown lifted across country on May 18, save hotspots; Gandhi urges Centre to make citizens 'psychologically' prepared to for lockdown exit




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Govt hikes borrowing limit by over 50% to Rs 12 trn as virus grips economy

Sources say the Centre has asked RBI to do whatever to keep yields in check, which may result in massive secondary market bond purchases




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Country's first round-the-clock solar power tender closes at Rs 2.9/unit

The project developer will have the option of building a hybrid plant with wind and hydro power or have energy storage systems




y

Lockdown period not to be counted for determining residency of NRIs: CBDT

There were apprehensions that this extended stay could lead to these individuals becoming Indian residents as per Section 6 of the Income Tax Act




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Working closely with states on labour reforms to help industry: Centre

The Confederation of Indian Industry (CII) suggested to the Labour Ministry to "direct workers to join back to their workplace" by issuing a circular




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Covid-19 lockdown effect: Every second Indian now on internet in cities

The data released by Nielsen and the Broadcast Audience Research Council (BARC) shows that internet usage has grown sharply in cities over the last one month, touching 54 per cent




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Additional borrowing to widen fiscal deficit, but help govt perk up economy

He did not think that the move will crowd out borrowings of the private sector, saying demand of the government and the private sector are not contradictory in these circumstances




y

FM to discuss credit flow to NBFCs, businesses with banks on Monday

The FM will take stock of the credit sanction and disbursement by the banks since March 1, 2020, and the Covid-19-related emergency credit lines opened by the lenders




y

Sitharaman launches two exchanges to take on offshore currency market

The launch comes amid the world's most expansive coronavirus lockdown, which has crippled businesses and hurt trading volumes in the country's financial markets.




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Covid-19: Relief for NRIs, foreign visitors as tax residency rules eased

The government imposed a lockdown on March 24 and is yet to open up travel, including international flights.




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Ministry of Defence inks Rs 1,200 cr contract to boost electronics sector

The deal, Modernisation of Air Field Infrastructure Phase 2 (MAFI-2), follows from an earlier contract, called MAFI-1, which TPSED won in 2011 to upgrade 30 IAF airfields.




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Lockdown worsening poverty levels among workers in informal economy: ILO

In high-income countries, relative poverty levels among informal workers are estimated to increase by 52 percentage points




y

Lockdown: Closure of commercial activity has hit Bihar, UP villages

But most respondents to a survey conducted by Smart Power India said they saw a positive change in social hygiene behaviour during lockdown




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Tamil Nadu CM asks PM to keep Electricity Amendment Bill on hold till talks

Proposed Bill takes away certain powers of the State government, and seeks to bring in changes in the existing Electricity Act that would make power utilities in the public sector totally unviable




y

Assam latest to go for labour reforms, plans raising work hours by 50%

Unlike other BJP-ruled states, it isn't doing away with most existing laws, but seeks to introduce fixed-term employment to facilitate direct hiring of contract labour by firms




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Adityanath seeks ways to boost tax revenue as UP misses April target by 90%

Chairing a review meeting here, Adityanath directed the revenue minister and other senior officials to look at additional sources of revenue and accelerate tax collection




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Miners want mandatory capex rule relaxed as workers stay away fearing Covid

None of the merchant mines in Odisha whose lease validity expired by March 31 has been able to restart. Though the successful bidders have got LoI, they awaiting formal vesting orders




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Release of graphene-related materials from epoxy-based composites: characterization, quantification and hazard assessment in vitro

Nanoscale, 2020, Advance Article
DOI: 10.1039/C9NR10245K, Paper
Open Access
Woranan Netkueakul, Daria Korejwo, Tobias Hammer, Savvina Chortarea, Patrick Rupper, Oliver Braun, Michel Calame, Barbara Rothen-Rutishauser, Tina Buerki-Thurnherr, Peter Wick, Jing Wang
We measured the cytotoxicity of pristine GRMs and the abraded particles from epoxy/GRM composites, which indicated low risks to consumers of such composites.
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RGD functionalized chitosan nanoparticle mediated targeted delivery of raloxifene selectively suppresses angiogenesis and tumor growth in breast cancer

Nanoscale, 2020, Advance Article
DOI: 10.1039/C9NR10673A, Paper
Amit S. Yadav, N. Naga Venkata Radharani, Mahadeo Gorain, Anuradha Bulbule, Dattatrya Shetti, Gaurab Roy, Thejus Baby, Gopal C. Kundu
Peptide functionalized pH sensitive raloxifene-chitosan nanoparticles with high biocompatibility synergistically inhibit tumor growth and angiogenesis in breast cancer.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Dy2@C79N: A New Member of Dimetalloazafullerenes with Strong Single Molecular Magnetism

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02519D, Paper
Yuanyuan Wang, Jin Xiong, Jie Su, Zi-Qi Hu, Fang Ma, Rong Sun, Xue-You Tan, Hao-Ling Sun, Bingwu Wang, Zujin Shi, Song Gao
Enhancing the exchange interaction between magnetic ions is a long-term target in molecular magnetism. Endohedral metallofullerenes (EMFs) provide a possibility for achieving such a goal by imprisoning multiple magnetic centers...
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Cellular Architecture Response to Aspect Ratio Tunable Nanoarrays

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01003K, Paper
Jing Dai, Jinkang Gong, Na Kong, Yuan Yao
Nanoarrays have been emerging as popular nanostructure platforms to investigate both cell behaviors and biological functions, due to the cell architecture respondence to biointerface of nanostructure. Herein, we developed a...
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Hybrid Phase 1T/2H-MoS2 with Controllable 1T Concentration and Its Promoted Hydrogen Evolution Reaction

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02525A, Paper
Yuxiao Zhang, Yasutaka Kuwahara, Kohsuke Mori, Catherine Louis, Hiromi Yamashita
MoS2 has been investigated as a low-cost alternative to Pt in electrochemical hydrogen evolution reaction. One of the promising method to further activate MoS2 is phase engineering. MoS2 generally exhibit...
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Multi-praseodymium-and-tungsten bridging octameric tellurotungstate and its 2D honeycomb composite film for detecting estrogen

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01901A, Paper
Yan Zhang, Jun JIang, Yifan Liu, Pan Li, Yong Liu, Lijuan Chen, Junwei Zhao
Under coordination driving force of tungsten and rare-earth (RE) bridges, we synthesized a novel giant multi-tungsten-and-RE—bridging octameric tellurotungstate (TT) [H2N(CH3)2]16K8Na6H10[Pr8(H2O)20W16O48][B-α-TeW9O33]8·70H2O (1) in CH3CN-H2O mixed solvent. The cluster anion {[Pr8(H2O)20W16O48][B-α-TeW9O33]8}40– features...
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Facile fabrication of sponge-like porous micropillar arrays via an electrochemical process

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR01518K, Paper
Deyin Zheng, Chang-Hwan Choi, Xin Zhao, Guangyi Sun
Highly ordered and aligned pore structures perpendicular to the exposed surfaces are achieved on the surfaces of 3D Si microstructures.
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Wrinkle-induced highly conductive channels in graphene on SiO2/Si substrate

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01406K, Paper
Ruisong Ma, Jiajun Ma, Jiahao Yan, Liangmei Wu, Wei Guo, Shuai Wang, Qing Huan, Lihong Bao, Sokrates T Pantelides, Hong-Jun Gao
Graphene wrinkle is a quasi-one-dimensional structure and can alter the intrinsic physical and chemical activity, modify the band structure and introduce transport anisotropy in graphene thin films. However, their quasi-one-dimensional...
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Plasma-assisted filling electron beam lithography for high throughput patterning of large area closed polygon nanostructures

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR01032D, Paper
You Sin Tan, Hailong Liu, Qifeng Ruan, Hao Wang, Joel K. W. Yang
The PFEBL process allows enhancement of electron beam writing efficiency for patterning of closed polygon structures using a post-exposure plasma treatment.
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Proton exchange membrane with plasmon-active surface for enhancement of fuel cell effectivity

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR00295J, Paper
Roman Elashnikov, Kristina Zahorjanova, Elena Miliutina, Zdenka Kolska, Miroslav Cieslar, Václav Švorčík, Oleksiy Lyutakov
The action of fuel cells with proton-exchanged membrane (PEM) requires the implementation of hydrogen oxidation reaction (HOR) and oxygen reduction reaction (ORR) on the opposite sides of PEM. Recently, based...
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