si

Pyridyl–triazole ligands enable in situ generation of a highly active dihydride iridium(III) complex for formic acid dehydrogenation

Inorg. Chem. Front., 2024, 11,7921-7929
DOI: 10.1039/D4QI01818D, Research Article
Miriam Abán, J. Marco Cuenca, Irene Embid, Alba de Toro, Pilar Gómez-Sal, Ernesto de Jesús, Marta Valencia, Cristina G. Yebra
[CpIr(CO)H2] efficiently catalyses formic acid dehydrogenation, forming in situ from pyridyl-triazole pre-catalysts [Cp*Ir(k2-NN)(Cl)][OTf]. Neat formic acid is dehydrogenated with a TON of up to 26876 and a TOF exceeding 10700 h−1.
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si

Highly defective and conductive Cu-doped 1T/2H-MoS2 nanosheets as high-capacity cathode materials for enhanced magnesium-ion storage

Inorg. Chem. Front., 2024, 11,7831-7842
DOI: 10.1039/D4QI02064B, Research Article
Ao Xu, Yan Liu, Jiahui Wang, Yijing Wang, Fuyi Jiang, Yanli Zhou
Limited by the poor electronic conductivity and strong interaction between Mg2+ and MoS2, the 2H phase of MoS2 as a cathode material exhibits low capacity and poor rate capability.
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si

Towards ultra-sensitive multimodal luminescent thermometers enabled by high crystal field strength of Lu2CaMg2Ge3O12:Yb3+,Nd3+,Er3+ phosphors

Inorg. Chem. Front., 2024, 11,7955-7965
DOI: 10.1039/D4QI01767F, Research Article
Zhijiao Zhao, Mengmeng Dai, Kejie Li, Guiying Liang, Yanling Wei, Zuoling Fu
An effective full-spectrum thermometer covering from the visible to NIR-II band was designed based on garnet Lu2CaMg2Ge3O12:Yb3+,Er3+/Nd3+ phosphors; meanwhile, Er3+ (4I13/2) split into four Stark sublevels due to high crystal field strength.
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si

A long-range synergistic effect between Ptn clusters and Zn1 single atoms for efficient selective hydrogenations

Inorg. Chem. Front., 2024, 11,7822-7830
DOI: 10.1039/D4QI02027H, Research Article
Haisheng Wei, Jing Li, Xiaorui Yan, Tiantian Liu, Kairui Li, Dan Feng, Yujing Ren
Benefiting from the long-range synergistic effect between Ptn clusters and Zn1 single atoms, Ptn@Zn1-N–C displays superior catalytic performance in selective hydrogenations.
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si

Photochromism-induced multi-mode optical modulations and fluorescent temperature sensing in Sr/Er-codoped (K0.5Na0.5)NbO3 ceramics

Inorg. Chem. Front., 2024, 11,8025-8036
DOI: 10.1039/D4QI01804D, Research Article
Fangyuan Yu, Qifa Lin, Xiangfu Zeng, Ping Zhou, Xiao Wu, Cong Lin, Chunlin Zhao, Min Gao, Tengfei Lin, Xingan Jiang, Laihui Luo, Qiwei Zhang
Sr/Er was codoped in KNN ceramics to induce the coexistence of O and T phases, resulting in improving optical transparency, maintaining moderate ferroelectricity, inducing excellent PC behavior and fluorescence temperature sensing performance.
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si

Unusual solvent-regulated inversion of a metal stereocenter in an enantiopure Eu2L4 helicate: a new strategy for CPL inversion

Inorg. Chem. Front., 2024, 11,8093-8100
DOI: 10.1039/D4QI02276A, Research Article
Qing Ma, Sen Yin, Ziye Song, Ting Gao, Pengfei Yan, Yanyan Zhou, Hongfeng Li
The dinuclear helicate Eu2(LR)4 exhibits a solvent-regulated metal stereocenter Δ/Λ configurational inversion, independent of P/M helical conformational conversion. This reversal process is accompanied by an inversion of the CPL.
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si

Linker engineering in mixed-ligand metal–organic frameworks for simultaneously enhanced benzene adsorption and benzene/cyclohexane separation

Inorg. Chem. Front., 2024, 11,8101-8109
DOI: 10.1039/D4QI01796J, Research Article
Yong-Zheng Zhang, Xin-Dan Zhang, Yan-Kai Zhang, Fu-Tian Wang, Longlong Geng, Hui Hu, Zhen Li, Da-Shuai Zhang, Hongliang Huang, Xiuling Zhang
A novel mixed-ligand metal–organic framework, featuring naphthalene rings in its secondary linker, exhibits exceptional benzene adsorption and separation capacities.
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si

Modulating the birefringence of two-dimensional hybrid lead bromide perovskites using pyridine derivative cations

Inorg. Chem. Front., 2024, 11,7853-7859
DOI: 10.1039/D4QI01547A, Research Article
Li-Ling Zhang, Hua Huang, Qingran Ding, Hui-Ping Xiao, Qing-Yan Liu, Yu-Ling Wang
Crystal structures and optoelectronic performance of hybrid two-dimensional lead bromide halide perovskites are elaborately regulated by pyridyl cations, which achieve a significantly enhanced birefringence of 0.315 (550 nm) for crystal 2.
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si

Active molecular units in metal organic frameworks for artificial photosynthesis

Inorg. Chem. Front., 2024, 11,7682-7755
DOI: 10.1039/D4QI01363H, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Subrata Mandal, Sahar Yoosefi, Alexander K. Mengele, Sven Rau, Andrea Pannwitz
Metal–organic frameworks (MOFs) integrate photoactive and catalytic entities within a 3D structure. This review classifies photocatalytic MOFs by photosensitizer and catalyst localization and their roles in artificial photosynthesis.
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si

Critical metal recovery from spent lithium-ion batteries’ leaching solution using electrodialysis technologies: strategies and challenges

Inorg. Chem. Front., 2024, 11,7775-7792
DOI: 10.1039/D4QI01978D, Review Article
Tianshu Zhang, Yijun Qian, Changyong Zhang, Tao Qian, Chenglin Yan
This review overviews the recent advances in electrodialysis (ED) in extracting critical metals from spent battery leachate. In addition, strategies and challenges regarding ED techniques toward battery recycling are pointed out.
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si

Dissecting the role of anions in surface reconstruction in urea oxidation to maximize assisted hydrogen production

Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02333A, Research Article
Weiwei Bao, Mameng Yang, Taotao Ai, Jie Han, Zhifeng Deng, Xiangyu Zou, Peng Jiang, Junjun Zhang
The oxygen-containing anion formed by electrooxidation and leaching on the electrode surface can effectively improve the catalytic activity of UOR and provide an accurate way for the energy saving hydrogen production assisted by urea.
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si

Stable solid-state potassium metal batteries enabled by a KB11H14·2Me3NBH3 complex electrolyte

Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02372B, Research Article
Guo-guo Zhang, Pengtao Qiu, Jiaxin Kang, Zhiwei Lu, An-qi Zhu, Xiaohu Yu, Xuenian Chen
Solid-state potassium metal batteries have increasingly gained attention as promising alternatives in large-scale energy storage due to their safety and low cost. However, these batteries usually suffer from a lack...
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si

Reversible single-crystal to single-crystal photoreaction between a coordination comb and a ladder displays photo-switchable fluorescence

Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02162B, Research Article
Ni-Ya Li, Xin-Yu Wang, Pei-Xuan Zhang, Ning-Ning Zou, Wen Qiu, Yu-Fei Xing, Yun-Jian Wang, Xiao-Yan Tang, Dong Liu
A unique coordination polymer can transform between comb-like and ladder-like bistable structures through reversible single-crystal-to-single-crystal photoreaction and exhibit photo-switchable fluorescence.
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si

Hierarchical FeCo LDH/NiSe heterostructure electrocatalysts with rich heterointerfaces for robust water splitting at industrial-level current density

Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02426E, Research Article
Weiwei Han, Wenyi Wang, Jiahong Liao, Yi He, Xingwang Zhang, Chunlin Yu
Sustainable hydrogen production by electrocatalytic water splitting is a promising energy storage technology yet challenging due to the sluggish kinetics of the oxygen evolution reaction (OER). Rationally designed robust and...
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si

Ionic-liquid/metal-organic-framework composites: Synthesis and emerging sustainable applications

Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02383H, Review Article
Maiyong Zhu
Ionic liquids (ILs) as emerging solvents have demonstrated a significant prospective in green chemistry, which can be used as green solvent, high efficiency catalyst, electrolyte, and so on. Metal–organic frameworks...
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si

Ultrathin 2D NiCo-MOF bimetallic nanosheets as single-atom catalysts for chemoselective hydrogenation of nitroarenes

Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02343A, Research Article
Yu-Xuan Zhang, Yi-Jie Ma, Yu-Jia Zhao, Zi-Yan Wang, Cai-Xia Yu, Xiaoqiang Li, Lei-Lei Liu
Exploration of non-noble-metal-based catalysts with high catalytic activity and selectivity is significant for driving innovation in green chemistry and technology. Herein, we report a facile synthesis of two-dimensional (2D) NiCo-MOF...
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si

Multistage construction of Gd-doped g-C3N4/Mo15S19 composites enabled both N2 activation and multiple electron transfer for an enhanced photocatalytic nitrogen reduction reaction

Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02016B, Research Article
Xiaoyu Jiang, Boran Tao, Hongda Li
A multistage construction of the Gd-doped g-C3N4/Mo15S19 catalyst, with Gd3+ as redox centers and Mo15S19 as N2 activation sites, synergistically enhances its photocatalytic NRR performance.
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si

Tunable luminescence via Cr3+–Yb3+/Nd3+ energy transfer in Cr3+ and Yb3+/Nd3+ coactivated NIR phosphors for non-destructive analysis

Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02260B, Research Article
Open Access
Xiaowei Zhang, Dashuai Sun, Pengcheng Luo, Luhui Zhou, Zheng Lu, Jia Liu, Congcong Fan, Xinyu Ye, Hongpeng You
Novel high-efficiency near-infrared phosphors with tunable luminescence via Cr3+–Yb3+/Nd3+ energy transfer for non-destructive analysis.
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si

Ammonia and formate cosynthesis via nitrate electroreduction combined with methanol electrooxidation over nitrogen-doped carbon-encapsulated nickel iron phosphide

Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02350A, Research Article
Zongyi Wang, Jiuli Chang, Zhiyong Gao
Nitrate–methanol co-electrolysis by the pairwise cathodic NO3RR and anodic MOR is a viable way to coproduce ammonia (NH3) and formate via gentle, sustainable and energy-saving “E-refining” and “E-reforming” means.
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si

Simple Aliovalent Cation Substitution to Induce Strong Optical Anisotropy Enhancement in Rare Thioantimonates (V) Family

Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02280G, Research Article
Qixian Ren, Wangfei Che, Mengmeng Chen, Chen Cui, Yabo Wu, Zhi Su
Thioantimonates containing high oxidation state Sb5+ have proven to exhibit excellent performance in the design of new materials such as infrared optics crystals and lithium-ion batteries. However, as described by...
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si

Dual-functional Applications of Photochromic BiNbO4: Er3+ Ceramics Based on Reversible Upconversion Luminescence Modulation

Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02440K, Research Article
ASAD ULLAH, Imran Khan, Yangke Cun, Yue Liu, Zhiguo Song, Jianbei Qiu, Tatiana Grigorievna Cherkasova, Anjun Huang, Asif Ali Haider, Zhengwen Yang
Photochromic luminescent phosphor has attracted considerable attention owing to its excellent optical properties, which face the problem of limited applications. Herein, the reversible photochromic and photo-/thermal bleaching phenomenon of BiNbO4...
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si

Pentagonal-bipyramidal Dysprosium(III) complexes with two apical phosphine oxide ligands and equatorial pentadentate N3O2 Schiff-base ligands: Breakdown of the apical magnetic axiality by strong equatorial crystal field†

Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02262A, Research Article
Tamara A. Bazhenova, Vyacheslav Kopotkov, Denis V. Korchagin, Elena Yureva, Michael V. Zhidkov, Alexey I Dmitriev, Ilya Yakushev, N. N. Efimov, Konstantin Andreevich Babeshkin, Vladimir Sergeevich Mironov, Eduard B. Yagubskii
A series of three new seven-coordinate pentagonal-bipyramidal (PBPY-7) Dy(III) complexes [Dy(LCH3)(Cy3PO)2]ClO4∙CH3CN (1), [Dy(L2(t-Bu))(Ph3PO)2]ClO4∙0.63C2H5OH (2), [Dy(LOCH3)(Ph3PO)2]ClO4∙2H2O (3) including various chelating pentadentate ligands with a [N3O2]2− binding node in the equatorial plane,...
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si

The use of single metal atoms-based photocatalysts for the production of ammonia through photocatalytic nitrogen fixation

Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02449D, Review Article
Ping Zhang, Yongchong Yu, Reyila Tuerhong, Xinyu Du, Keyi Chai, Xiaoping Su, Qiong Su, Shujuan Meng, Lijuan Han
The conventional synthetic ammonia industry is characterized by its high energy consumption, necessitating the exploration of a new environmentally sustainable method for NH3 synthesis. A prospective alternative to the Haber-Bosch...
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si

Metal Node Exchange-Driven Ligand-Strain Modulation Strategy for One-Dimensional Crystalline Coordination Polymers

Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02422B, Research Article
Gengxin Wu, Yong-Kang Zhu, Dongxia Li, Jia-Rui Wu, Yan Wang, Zhiquan Zhang, Ying-Wei Yang
Engineering ideal functional coordination polymers (CPs) via post-synthetic modification has emerged as a powerful synthetic strategy to achieve desirable functionalities and superior properties. In this work, we report a versatile...
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si

Nanoscale sorting of extracellular vesicles via optically-induced dielectrophoresis on an integrated microfluidic system

Lab Chip, 2024, 24,1965-1976
DOI: 10.1039/D3LC01007D, Paper
Wei-Jen Soong, Chih-Hung Wang, Chihchen Chen, Gwo-Bin Lee
We devised an innovative method for automated sorting of extracellular vesicles (EVs) employing optically-induced dielectrophoresis on an integrated microfluidic chip. EVs of three distinct size categories could be isolated in 1 h at a purity of 86%.
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si

Capturing of extracellular vesicles derived from single cells of Escherichia coli

Lab Chip, 2024, 24,2049-2057
DOI: 10.1039/D3LC00707C, Paper
Open Access
Fumiaki Yokoyama, André Kling, Petra S. Dittrich
A microdevice with narrow winding channels is introduced to trap and culture single bacterial cells. It is used to study growth patterns of the cells and to monitor secretion of extracellular vesicles under treatment with an antibiotic drug.
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si

Test strip coupled Cas12a-assisted signal amplification strategy for sensitive detection of uracil-DNA glycosylase

Lab Chip, 2024, 24,1987-1995
DOI: 10.1039/D4LC00096J, Paper
Bin Guo, Chong Hu, Zeping Yang, Chu Tang, Chuanxian Zhang, Fu Wang
In this study, we employed Cas12a protein and enzyme-assisted cycle amplification technology with a test strip to establish a precise platform for the detection of UDG enzyme.
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si

Wearable intelligent sweat platform for SERS-AI diagnosis of gout

Lab Chip, 2024, 24,1996-2004
DOI: 10.1039/D3LC01094E, Paper
Zhaoxian Chen, Wei Wang, Hao Tian, Wenrou Yu, Yu Niu, Xueli Zheng, Shihong Liu, Li Wang, Yingzhou Huang
A wearable intelligent SERS platform enables the sensitive detection of UA (0.1 μM) in sweat for AI diagnosis of gout.
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si

AMF-SporeChip provides new insights into arbuscular mycorrhizal fungal asymbiotic hyphal growth dynamics at the cellular level

Lab Chip, 2024, 24,1930-1946
DOI: 10.1039/D3LC00859B, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Felix Richter, Maryline Calonne-Salmon, Marcel G. A. van der Heijden, Stéphane Declerck, Claire E. Stanley
A new microfluidic platform – the AMF-SporeChip – enables immobilisation of arbuscular mycorrhizal fungal spores and confrontation of asymbiotic hyphae with physical obstacles, allowing the identification of various exploration strategies.
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si

Microfluidic impedance cytometry with flat-end cylindrical electrodes for accurate and fast analysis of marine microalgae

Lab Chip, 2024, 24,2058-2068
DOI: 10.1039/D3LC00942D, Paper
Xiaoming Chen, Mo Shen, Shun Liu, Chungang Wu, Liangliang Sun, Zhipeng Song, Jishun Shi, Yulong Yuan, Yong Zhao
We develop a novel microfluidic impedance cytometer for analysis of marine microalgae by inserting ground flat-end cylindrical electrodes into microchannels.
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si

Multifunctional cardiac microphysiological system based on transparent ITO electrodes for simultaneous optical measurement and electrical signal monitoring

Lab Chip, 2024, 24,1903-1917
DOI: 10.1039/D3LC00908D, Paper
Zhangjie Li, Kai Niu, Chenyang Zhou, Feifan Wang, Kangyi Lu, Yijun Liu, Lian Xuan, Xiaolin Wang
We developed a multifunctional cardiac microphysiological system on transparent electrodes, enabling simultaneous electrical signal monitoring and optical observations of cardiac tissue, holding promise for applications in cardiac drug development.
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si

Microphysiological pancreas-on-chip platform with integrated sensors to model endocrine function and metabolism

Lab Chip, 2024, 24,2080-2093
DOI: 10.1039/D3LC00838J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Katharina Schlünder, Madalena Cipriano, Aline Zbinden, Stefanie Fuchs, Torsten Mayr, Katja Schenke-Layland, Peter Loskill
Pancreatic in vitro models are crucial for research on diseases such as diabetes mellitus. A novel thermoplastic organ-on-chip with integrated real-time read-outs models the complex microphysiological structure and function of the endocrine pancreas.
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si

Deciphering fibroblast-induced drug resistance in non-small cell lung carcinoma through patient-derived organoids in agarose microwells

Lab Chip, 2024, 24,2025-2038
DOI: 10.1039/D3LC01044A, Paper
Qiyue Luan, Ines Pulido, Angelique Isagirre, Julian Carretero, Jian Zhou, Takeshi Shimamura, Ian Papautsky
Agarose microwell platform for modeling lung carcinoma using patient-derived tissues to decipher cancer associated fibroblast-induced drug resistance.
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si

Tonicity-induced cargo loading into extracellular vesicles

Lab Chip, 2024, 24,2069-2079
DOI: 10.1039/D3LC00830D, Paper
Open Access
Chaeeun Lee, Sumit Kumar, Juhee Park, Yongjun Choi, Elizabeth Maria Clarissa, Yoon-Kyoung Cho
Tonicity-induced cargo loading into extracellular vesicles (EVs) is achieved through controlled membrane permeability, ensuring cargo incorporation without causing damage to the EV membrane.
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si

Droplet microfluidic system for high throughput and passive selection of bacteria producing biosurfactants

Lab Chip, 2024, 24,1947-1956
DOI: 10.1039/D3LC00656E, Paper
Open Access
Klaudia Staskiewicz, Maria Dabrowska-Zawada, Lukasz Kozon, Zofia Olszewska, Lukasz Drewniak, Tomasz S. Kaminski
Novel microfluidic technique for functional selection of biosurfactant-producing microorganisms. Single bacterial cells are encapsulated into picoliter droplets for clonal cultivation and passively sorted at high throughput by interfacial tension.
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si

A self-assembly and cellular migration based fabrication of high-density 3D tubular constructs of barrier forming membranes

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00006D, Paper
Seyedaydin Jalali, Ponnambalam Ravi Selvaganapathy
A scalable method for creating perfusable 3D tissue constructs using self-assembly is introduced. Unlike conventional cell injection methods, here we leverage cell migration to form tissue barriers of low permeability, mimicking in vivo environments.
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si

Spatially controlled diffusion range of tumor-associated angiogenic factors to develop a tumor model using a microfluidic resistive circuit

Lab Chip, 2024, Advance Article
DOI: 10.1039/D3LC00891F, Paper
Yu-Hsiang Hsu, Wen-Chih Yang, Yi-Ting Chen, Che-Yu Lin, Chiou-Fong Yang, Wei-Wen Liu, Subhashree Shivani, Pai-Chi Li
The DC-MPS device uses a velocity V-clamp to create a partition with a steep concentration gradient for simultaneously developing vasculogenic vessels and a tumor. It enables vessel–tumor interaction to develop a tumor model with angiogenic vessels.
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si

Evaluating thrombosis risk and patient-specific treatment strategy using an atherothrombosis-on-chip model

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00131A, Paper
Fahima Akther, Hedieh Fallahi, Jun Zhang, Nam-Trung Nguyen, Hang Thu Ta
An atherothrombosis-on-chip model to evaluate thrombosis risk and patient-specific treatment strategy.
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si

Detection and Identification of Single Ribonucleotide Monophosphates using a Dual In-Plane Nanopore Sensor Made from a Thermoplastic via Replication

Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D3LC01062G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Steven A. Soper, Chathurika Rathnayaka, Indu Chandrasoma, Junseo Choi, Katie Childers, Maximillian Chibuike, Khurshed Akabirov, Farhad Shiri, Adam R Hall, Collin J McKinney, Matthew David Verber, Sunggook Park
We report the generation of ~8 nm dual in-plane pores fabricated in a thermoplastic via nanoimprint lithography (NIL). These pores were connected in series with nanochannels, one of which served...
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si

Operando scanning electron microscopy platform for in situ imaging of fluid evolution in nanoporous shale

Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D3LC01066J, Paper
Open Access
Artur Davletshin, Wen Song
Fluid-solid interactions in nanoporous materials underlie processes fundamental to nature and the engineered environment, including the thermochemical transformation of argillaceous materials during high-level nuclear waste disposal. Operando fluid-solid resolution at...
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si

An economical in-class sticker microfluidic activity develops student expertise in microscale physics and device manufacturing

Lab Chip, 2024, 24,2176-2192
DOI: 10.1039/D3LC00912B, Paper
Open Access
Priscilla Delgado, C. Alessandra Luna, Anjana Dissanayaka, Oluwamayokun Oshinowo, Jesse J. Waggoner, Sara Schley, Todd Fernandez, David R. Myers
This activity enables students to construct geometrically complex microfluidics at their desk with no specialized equipment. It can be easily transported, and helped students significantly improve their understanding of miniaturization science.
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si

Synthesis and photocatalytic property of Au–TiO2 nanocomposites with controlled morphologies in microfluidic chips

Lab Chip, 2024, 24,2253-2261
DOI: 10.1039/D3LC01053H, Paper
Ziran Ye, Ping Lu, Yiben Chen, Zhixian Xu, Haixia Huang, Mingjia Zhi, Zi Ang Chen, Bo Yan
We present an efficient approach for the consecutive synthesis of Au–TiO2 nanocomposites with controlled morphologies in a microfluidic chip.
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si

Deep learning-enabled detection of rare circulating tumor cell clusters in whole blood using label-free, flow cytometry

Lab Chip, 2024, 24,2237-2252
DOI: 10.1039/D3LC00694H, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Nilay Vora, Prashant Shekar, Taras Hanulia, Michael Esmail, Abani Patra, Irene Georgakoudi
We present a deep-learning enabled, label-free flow cytometry platform for identifying circulating tumor cell clusters in whole blood based on the endogenous scattering detected at three wavelengths. The method has potential for in vivo translation.
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si

Distance-based paper analytical device for multiplexed quantification of cytokine biomarkers using carbon dots integrated with molecularly imprinted polymer

Lab Chip, 2024, 24,2262-2271
DOI: 10.1039/D4LC00055B, Paper
Kawin Khachornsakkul, Ruben Del-Rio-Ruiz, Lita Chheang, Wenxin Zeng, Sameer Sonkusale
A carbon dots and dopamine-imprinted polymer was immobilized onto a distance-based paper channel for simultaneous detection of three cytokine biomarkers without requiring expensive reagents and instruments.
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si

Correction: Integrated biosensors for monitoring microphysiological systems

Lab Chip, 2024, 24,2358-2359
DOI: 10.1039/D4LC90026J, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Lei Mou, Kalpana Mandal, Marvin Magan Mecwan, Ana Lopez Hernandez, Surjendu Maity, Saurabh Sharma, Rondinelli Donizetti Herculano, Satoru Kawakita, Vadim Jucaud, Mehmet Remzi Dokmeci, Ali Khademhosseini
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si

A cheaper substitute for HRP: ultra-small Cu–Au bimetallic enzyme mimics with infinitesimal steric hindrance to promote catalytic lateral flow immunodetection of clenbuterol

Lab Chip, 2024, 24,2272-2279
DOI: 10.1039/D3LC01079A, Paper
Huilan Hu, Jiaqi Tian, Rui Shu, Huihui Liu, Shaochi Wang, Xuechi Yin, Jianlong Wang, Daohong Zhang
A lateral flow immunoassay (LFIA) is developed for enzyme-catalyzed double-reading determination of clenbuterol (CLE) through the direct electrostatic adsorption of ultra-small copper–gold bimetallic enzyme mimics (USCGs) and monoclonal antibodies.
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si

A surface-engineered contact lens for tear fluid biomolecule sensing

Lab Chip, 2024, 24,2327-2334
DOI: 10.1039/D4LC00176A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Aravind M, Sajan D. George
Adhesive contrast contact lens fabricated by selective lubricant grafting splits tear film on specified zone by secretion and blinking. Integrating the contact lens with the spectroscopic technique offers an efficient platform for biomolecule sensing.
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si

Designing and prototyping a novel biosensor based on a volumetric bar-chart chip for urea detection

Lab Chip, 2024, 24,2298-2305
DOI: 10.1039/D3LC00730H, Paper
Mahdi Samadi Khezri, Mohammad Reza Housaindokht, Mojtaba Firouzi
A volumetric bar-chart chip (V-chip) is a microfluidic device based on distance-based quantitative measurement that visualizes analyte concentration without the need for apparatus or data processing.
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si

A novel ratiometric design of microfluidic paper-based analytical device for the simultaneous detection of Cu2+ and Fe3+ in drinking water using a fluorescent MOF@tetracycline nanocomposite

Lab Chip, 2024, 24,2306-2316
DOI: 10.1039/D3LC01045G, Paper
Sabah H. Al-Jaf, Sameera Sh. Mohammed Ameen, Khalid M. Omer
On-site monitoring of ions in drinking water is essential for safeguarding public health, ensuring high water quality, and preserving the ecological balance of aquatic ecosystems.
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Vascularized tissue on mesh-assisted platform (VT-MAP): a novel approach for diverse organoid size culture and tailored cancer drug response analysis

Lab Chip, 2024, 24,2208-2223
DOI: 10.1039/D3LC01055D, Paper
Open Access
Jungseub Lee, Sangmin Jung, Hye Kyoung Hong, Hyeonsu Jo, Stephen Rhee, Ye-Lin Jeong, Jihoon Ko, Yong Beom Cho, Noo Li Jeon
VT-MAP, a novel in vitro platform, offers better physiological reflection through the vascularized organoid. This advancement supports drug assessment with deeper insights into cancer biology through correlation between morphology and drug effects.
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