i Anarchy in Venezuela's jails laid bare by massacre over food By news.yahoo.com Published On :: Fri, 08 May 2020 13:27:04 -0400 Three weeks before he was shot dead, Miguel Calderon, an inmate in the lawless Los Llanos jail on Venezuela's central plains, sent a voice message to his father. Like many of the prisoners in Venezuela's overcrowded and violent penitentiaries, Los Llanos's 4,000 inmates normally subsist on food relatives bring them. The guards, desperate themselves amid national shortages, began stealing the little food getting behind bars, inmates said, forcing some prisoners to turn to eating stray animals. Full Article
i Russia probe transcripts released by House Intelligence Committee By news.yahoo.com Published On :: Thu, 07 May 2020 23:20:04 -0400 Reaction and analysis from Fox News contributor Byron York and former Florida Attorney General Pam Bondi. Full Article
i Pence aimed to project normalcy during his trip to Iowa, but coronavirus got in the way By news.yahoo.com Published On :: Fri, 08 May 2020 21:35:24 -0400 Vice President Pence’s trip to Iowa shows how the Trump administration’s aims to move past coronavirus are sometimes complicated by the virus itself. Full Article
i Federal watchdog finds 'reasonable grounds to believe' vaccine doctor's ouster was retaliation, lawyers say By news.yahoo.com Published On :: Fri, 08 May 2020 16:37:13 -0400 The Office of Special Counsel is recommending that ousted vaccine official Dr. Rick Bright be reinstated while it investigates his case, his lawyers announced Friday.Bright while leading coronavirus vaccine development was recently removed from his position as the director of the Department of Health and Human Services' Biomedical Advanced Research and Development Authority, and he alleges it was because he insisted congressional funding not go toward "drugs, vaccines, and other technologies that lack scientific merit" and limited the "broad use" of hydroxychloroquine after it was touted by President Trump. In a whistleblower complaint, he alleged "cronyism" at HHS. He has also alleged he was "pressured to ignore or dismiss expert scientific recommendations and instead to award lucrative contracts based on political connections."On Friday, Bright's lawyers said that the Office of Special Counsel has determined there are "reasonable grounds to believe" his firing was retaliation, The New York Times reports. The federal watchdog also recommended he be reinstated for 45 days to give the office "sufficient time to complete its investigation of Bright's allegations," CNN reports. The decision on whether to do so falls on Secretary of Health and Human Services Alex Azar, and Office of Special Counsel recommendations are "not binding," the Times notes. More stories from theweek.com Outed CIA agent Valerie Plame is running for Congress, and her launch video looks like a spy movie trailer 7 scathing cartoons about America's rush to reopen Trump says he couldn't have exposed WWII vets to COVID-19 because the wind was blowing the wrong way Full Article
i Train kills 15 migrant workers walking home in India By news.yahoo.com Published On :: Fri, 08 May 2020 00:56:54 -0400 A train in India on Friday plowed through a group of migrant workers who fell asleep on the tracks after walking back home from a coronavirus lockdown, killing 15, the Railways Ministry said. Early this week the government started running trains to carry stranded workers to their home states. Full Article
i India uses drones to disinfect virus hotspot as cases surge By news.yahoo.com Published On :: Sat, 09 May 2020 11:19:33 -0400 Indian authorities used drones and fire engines to disinfect the pandemic-hit city of Ahmedabad on Saturday, as virus cases surged and police clashed with migrant workers protesting against a reinforced lockdown. The western city of 5.5 million people in Prime Minister Narendra Modi's home state has become a major concern for authorities as they battle an uptick in coronavirus deaths and cases across India. Full Article
i U.S. chief justice puts hold on disclosure of Russia investigation materials By news.yahoo.com Published On :: Fri, 08 May 2020 11:50:21 -0400 U.S. Chief Justice John Roberts on Friday put a temporary hold on the disclosure to a Democratic-led House of Representatives committee of grand jury material redacted from former Special Counsel Robert Mueller's report on Russian interference in the 2016 election. The U.S. Court of Appeals for the District of Columbia Circuit ruled in March that the materials had to be disclosed to the House Judiciary Committee and refused to put that decision on hold. The appeals court said the materials had to be handed over by May 11 if the Supreme Court did not intervene. Full Article
i Boeing says it's about to start building the 737 Max plane again in the middle of the coronavirus pandemic, even though it already has more planes than it can deliver By news.yahoo.com Published On :: Fri, 08 May 2020 12:44:06 -0400 Boeing CEO Dave Calhoun said the company was aiming to resume production this month, despite the ongoing grounding and coronavirus pandemic. Full Article
i These are the most dangerous jobs you can have in the age of coronavirus By news.yahoo.com Published On :: Fri, 08 May 2020 19:34:48 -0400 For millions of Americans, working at home isn't an option. NBC News identified seven occupations in which employees are at especially high risk of COVID-19. Full Article
i Delta, citing health concerns, drops service to 10 US airports. Is yours on the list? By news.yahoo.com Published On :: Fri, 08 May 2020 18:41:45 -0400 Delta said it is making the move to protect employees amid the coronavirus pandemic, but planes have been flying near empty Full Article
i Chaffetz: I don't understand why Adam Schiff continues to have a security clearance By news.yahoo.com Published On :: Fri, 08 May 2020 14:43:30 -0400 Fox News contributor Jason Chaffetz and Andy McCarthy react to House Intelligence transcripts on Russia probe. Full Article
i As Trump returns to the road, some Democrats want to bust Biden out of his basement By news.yahoo.com Published On :: Fri, 08 May 2020 17:49:42 -0400 While President Donald Trump traveled to the battleground state of Arizona this week, his Democratic opponent for the White House, Joe Biden, campaigned from his basement as he has done throughout the coronavirus pandemic. The freeze on in-person campaigning during the outbreak has had an upside for Biden, giving the former vice president more time to court donors and shielding him from on-the-trail gaffes. "I personally would like to see him out more because he's in his element when he's meeting people," said Tom Sacks-Wilner, a fundraiser for Biden who is on the campaign's finance committee. Full Article
i A person was struck and killed by a Southwest plane as it landed on the runway at Austin international airport By news.yahoo.com Published On :: Fri, 08 May 2020 10:53:00 -0400 Austin-Bergstrom International Airport said it was "aware of an individual that was struck and killed on runway 17-R by a landing aircraft." Full Article
i Coronavirus deals 'powerful blow' to Putin's grand plans By news.yahoo.com Published On :: Thu, 07 May 2020 22:09:16 -0400 The bombastic military parade through Moscow's Red Square on Saturday was slated to be the spectacle of the year on the Kremlin's calendar. Standing with Chinese leader Xi Jinping and French President Emmanuel Macron, President Vladimir Putin would have overseen a 90-minute procession of Russia's military might, showcasing 15,000 troops and the latest hardware. Now, military jets will roar over an eerily quiet Moscow, spurting red, white and blue smoke to mark 75 years since the defeat of Nazi Germany. Full Article
i 'We Cannot Police Our Way Out of a Pandemic.' Experts, Police Union Say NYPD Should Not Be Enforcing Social Distance Rules Amid COVID-19 By news.yahoo.com Published On :: Thu, 07 May 2020 17:03:38 -0400 The New York City police department (NYPD) is conducting an internal investigation into a May 2 incident involving the violent arrests of multiple people, allegedly members of a group who were not social distancing Full Article
i Pence staffer who tested positive for coronavirus is Stephen Miller's wife By news.yahoo.com Published On :: Fri, 08 May 2020 15:33:00 -0400 The staffer of Vice President Mike Pence who tested positive for coronavirus is apparently his press secretary and the wife of White House senior adviser Stephen Miller.Reports emerged on Friday that a member of Pence's staff had tested positive for COVID-19, creating a delay in his flight to Iowa amid concern over who may have been exposed. Later in the day, Trump said the staffer is a "press person" named Katie.Politico reported he was referring to Katie Miller, Pence's press secretary and the wife of Stephen Miller. This report noted this raises the risk that "a large swath of the West Wing's senior aides may also have been exposed." She confirmed her positive diagnosis to NBC News, saying she does not have symptoms.Trump spilled the beans to reporters, saying Katie Miller "hasn't come into contact with me" but has "spent some time with the vice president." This news comes one day after a personal valet to Trump tested positive for COVID-19, which reportedly made the president "lava level mad." Pence and Trump are being tested for COVID-19 every day.Asked Friday if he's concerned about the potential spread of coronavirus in the White House, Trump said "I'm not worried, no," adding that "we've taken very strong precautions."More stories from theweek.com Outed CIA agent Valerie Plame is running for Congress, and her launch video looks like a spy movie trailer 7 scathing cartoons about America's rush to reopen Trump says he couldn't have exposed WWII vets to COVID-19 because the wind was blowing the wrong way Full Article
i ‘Selfish, tribal and divided’: Barack Obama warns of changes to American way of life in leaked audio slamming Trump administration By news.yahoo.com Published On :: Sat, 09 May 2020 07:22:00 -0400 Barack Obama said the “rule of law is at risk” following the justice department’s decision to drop charges against former Trump advisor Mike Flynn, as he issued a stark warning about the long-term impact on the American way of life by his successor. Full Article
i New Zealand says it backs Taiwan's role in WHO due to success with coronavirus By news.yahoo.com Published On :: Thu, 07 May 2020 23:20:43 -0400 Full Article
i Almost 12,000 meatpacking and food plant workers have reportedly contracted COVID-19. At least 48 have died. By news.yahoo.com Published On :: Fri, 08 May 2020 12:21:01 -0400 The infections and deaths are spread across roughly two farms and 189 meat and processed food factories. Full Article
i Cruz gets his hair cut at salon whose owner was jailed for defying Texas coronavirus restrictions By news.yahoo.com Published On :: Fri, 08 May 2020 19:28:43 -0400 After his haircut, Sen. Ted Cruz said, "It was ridiculous to see somebody sentenced to seven days in jail for cutting hair." Full Article
i Meet the Ohio health expert who has a fan club — and Republicans trying to stop her By news.yahoo.com Published On :: Sat, 09 May 2020 05:04:00 -0400 Some Buckeyes are not comfortable being told by a "woman in power" to quarantine, one expert said. Full Article
i Brazil's Amazon: Surge in deforestation as military prepares to deploy By news.yahoo.com Published On :: Fri, 08 May 2020 17:17:52 -0400 The military is preparing to deploy to the region to try to stop illegal logging and mining. Full Article
i The McMichaels can't be charged with a hate crime by the state in the shooting death of Ahmaud Arbery because the law doesn't exist in Georgia By news.yahoo.com Published On :: Fri, 08 May 2020 17:07:36 -0400 Georgia is one of four states that doesn't have a hate crime law. Arbery's killing has reignited calls for legislation. Full Article
i CNN legal analysts say Barr dropping the Flynn case shows 'the fix was in.' Barr says winners write history. By news.yahoo.com Published On :: Fri, 08 May 2020 08:23:00 -0400 The Justice Department announced Thursday that it is dropping its criminal case against President Trump's first national security adviser Michael Flynn. Flynn twice admitted in court he lied to the FBI about his conversations with Russia's U.S. ambassador, and then cooperated in Special Counsel Robert Mueller's investigation. It was an unusual move by the Justice Department, and CNN's legal and political analysts smelled a rat."Attorney General [William] Barr is already being accused of creating a special justice system just for President Trump's friends," and this will only feed that perception, CNN's Jake Tapper suggested. Political correspondent Sara Murray agreed, noting that the prosecutor in the case, Brandon Van Grack, withdrew right before the Justice Department submitted its filing, just like when Barr intervened to request a reduced sentence for Roger Stone.National security correspondent Jim Sciutto laid out several reason why the substance of Flynn's admitted lie was a big deal, and chief legal analyst Jeffrey Toobin was appalled. "It is one of the most incredible legal documents I have read, and certainly something that I never expected to see from the United States Department of Justice," Toobin said. "The idea that the Justice Department would invent an argument -- an argument that the judge in this case has already rejected -- and say that's a basis for dropping a case where a defendant admitted his guilt shows that this is a case where the fix was in."Barr told CBS News' Cathrine Herridge on Thursday that dropping Flynn's case actually "sends the message that there is one standard of justice in this country." Herridge told Barr he would take flak for this, asking: "When history looks back on this decision, how do you think it will be written?" Barr laughed: "Well, history's written by the winners. So it largely depends on who's writing the history." Watch below. More stories from theweek.com Outed CIA agent Valerie Plame is running for Congress, and her launch video looks like a spy movie trailer 7 scathing cartoons about America's rush to reopen Trump says he couldn't have exposed WWII vets to COVID-19 because the wind was blowing the wrong way Full Article
i The accusation against Joe Biden has Democrats rediscovering the value of due process By news.yahoo.com Published On :: Sat, 09 May 2020 08:37:00 -0400 Some Democrats took "Believe Women" literally until Joe Biden was accused. Now they're relearning that guilt-by-accusation doesn't serve justice. Full Article
i Nearly one-third of Americans believe a coronavirus vaccine exists and is being withheld, survey finds By news.yahoo.com Published On :: Fri, 08 May 2020 16:49:35 -0400 The Democracy Fund + UCLA Nationscape Project found some misinformation about the coronavirus is more widespread that you might think. Full Article
i Pence press secretary tests positive for coronavirus By news.yahoo.com Published On :: Fri, 08 May 2020 18:23:49 -0400 The news comes shortly after a valet who served meals to President Trump also tested positive for the virus. Full Article
i Coronavirus: Chinese official admits health system weaknesses By news.yahoo.com Published On :: Sat, 09 May 2020 11:02:40 -0400 China says it will improve public health systems after criticism of its early response to the virus. Full Article
i Neighbor of father and son arrested in Ahmaud Arbery killing is also under investigation By news.yahoo.com Published On :: Fri, 08 May 2020 11:42:19 -0400 The ongoing investigation of the fatal shooting in Brunswick, Georgia, will also look at a neighbor of suspects Gregory and Travis McMichael who recorded video of the incident, authorities said. Full Article
i Bayesian Quantile Regression with Mixed Discrete and Nonignorable Missing Covariates By projecteuclid.org Published On :: Thu, 19 Mar 2020 22:02 EDT Zhi-Qiang Wang, Nian-Sheng Tang. Source: Bayesian Analysis, Volume 15, Number 2, 579--604.Abstract: Bayesian inference on quantile regression (QR) model with mixed discrete and non-ignorable missing covariates is conducted by reformulating QR model as a hierarchical structure model. A probit regression model is adopted to specify missing covariate mechanism. A hybrid algorithm combining the Gibbs sampler and the Metropolis-Hastings algorithm is developed to simultaneously produce Bayesian estimates of unknown parameters and latent variables as well as their corresponding standard errors. Bayesian variable selection method is proposed to recognize significant covariates. A Bayesian local influence procedure is presented to assess the effect of minor perturbations to the data, priors and sampling distributions on posterior quantities of interest. Several simulation studies and an example are presented to illustrate the proposed methodologies. Full Article
i Bayesian Sparse Multivariate Regression with Asymmetric Nonlocal Priors for Microbiome Data Analysis By projecteuclid.org Published On :: Thu, 19 Mar 2020 22:02 EDT Kurtis Shuler, Marilou Sison-Mangus, Juhee Lee. Source: Bayesian Analysis, Volume 15, Number 2, 559--578.Abstract: We propose a Bayesian sparse multivariate regression method to model the relationship between microbe abundance and environmental factors for microbiome data. We model abundance counts of operational taxonomic units (OTUs) with a negative binomial distribution and relate covariates to the counts through regression. Extending conventional nonlocal priors, we construct asymmetric nonlocal priors for regression coefficients to efficiently identify relevant covariates and their effect directions. We build a hierarchical model to facilitate pooling of information across OTUs that produces parsimonious results with improved accuracy. We present simulation studies that compare variable selection performance under the proposed model to those under Bayesian sparse regression models with asymmetric and symmetric local priors and two frequentist models. The simulations show the proposed model identifies important covariates and yields coefficient estimates with favorable accuracy compared with the alternatives. The proposed model is applied to analyze an ocean microbiome dataset collected over time to study the association of harmful algal bloom conditions with microbial communities. Full Article
i A Loss-Based Prior for Variable Selection in Linear Regression Methods By projecteuclid.org Published On :: Thu, 19 Mar 2020 22:02 EDT Cristiano Villa, Jeong Eun Lee. Source: Bayesian Analysis, Volume 15, Number 2, 533--558.Abstract: In this work we propose a novel model prior for variable selection in linear regression. The idea is to determine the prior mass by considering the worth of each of the regression models, given the number of possible covariates under consideration. The worth of a model consists of the information loss and the loss due to model complexity. While the information loss is determined objectively, the loss expression due to model complexity is flexible and, the penalty on model size can be even customized to include some prior knowledge. Some versions of the loss-based prior are proposed and compared empirically. Through simulation studies and real data analyses, we compare the proposed prior to the Scott and Berger prior, for noninformative scenarios, and with the Beta-Binomial prior, for informative scenarios. Full Article
i Function-Specific Mixing Times and Concentration Away from Equilibrium By projecteuclid.org Published On :: Thu, 19 Mar 2020 22:02 EDT Maxim Rabinovich, Aaditya Ramdas, Michael I. Jordan, Martin J. Wainwright. Source: Bayesian Analysis, Volume 15, Number 2, 505--532.Abstract: Slow mixing is the central hurdle is applications of Markov chains, especially those used for Monte Carlo approximations (MCMC). In the setting of Bayesian inference, it is often only of interest to estimate the stationary expectations of a small set of functions, and so the usual definition of mixing based on total variation convergence may be too conservative. Accordingly, we introduce function-specific analogs of mixing times and spectral gaps, and use them to prove Hoeffding-like function-specific concentration inequalities. These results show that it is possible for empirical expectations of functions to concentrate long before the underlying chain has mixed in the classical sense, and we show that the concentration rates we achieve are optimal up to constants. We use our techniques to derive confidence intervals that are sharper than those implied by both classical Markov-chain Hoeffding bounds and Berry-Esseen-corrected central limit theorem (CLT) bounds. For applications that require testing, rather than point estimation, we show similar improvements over recent sequential testing results for MCMC. We conclude by applying our framework to real-data examples of MCMC, providing evidence that our theory is both accurate and relevant to practice. Full Article
i Joint Modeling of Longitudinal Relational Data and Exogenous Variables By projecteuclid.org Published On :: Thu, 19 Mar 2020 22:02 EDT Rajarshi Guhaniyogi, Abel Rodriguez. Source: Bayesian Analysis, Volume 15, Number 2, 477--503.Abstract: This article proposes a framework based on shared, time varying stochastic latent factor models for modeling relational data in which network and node-attributes co-evolve over time. Our proposed framework is flexible enough to handle both categorical and continuous attributes, allows us to estimate the dimension of the latent social space, and automatically yields Bayesian hypothesis tests for the association between network structure and nodal attributes. Additionally, the model is easy to compute and readily yields inference and prediction for missing link between nodes. We employ our model framework to study co-evolution of international relations between 22 countries and the country specific indicators over a period of 11 years. Full Article
i Bayesian Inference in Nonparanormal Graphical Models By projecteuclid.org Published On :: Thu, 19 Mar 2020 22:02 EDT Jami J. Mulgrave, Subhashis Ghosal. Source: Bayesian Analysis, Volume 15, Number 2, 449--475.Abstract: Gaussian graphical models have been used to study intrinsic dependence among several variables, but the Gaussianity assumption may be restrictive in many applications. A nonparanormal graphical model is a semiparametric generalization for continuous variables where it is assumed that the variables follow a Gaussian graphical model only after some unknown smooth monotone transformations on each of them. We consider a Bayesian approach in the nonparanormal graphical model by putting priors on the unknown transformations through a random series based on B-splines where the coefficients are ordered to induce monotonicity. A truncated normal prior leads to partial conjugacy in the model and is useful for posterior simulation using Gibbs sampling. On the underlying precision matrix of the transformed variables, we consider a spike-and-slab prior and use an efficient posterior Gibbs sampling scheme. We use the Bayesian Information Criterion to choose the hyperparameters for the spike-and-slab prior. We present a posterior consistency result on the underlying transformation and the precision matrix. We study the numerical performance of the proposed method through an extensive simulation study and finally apply the proposed method on a real data set. Full Article
i Additive Multivariate Gaussian Processes for Joint Species Distribution Modeling with Heterogeneous Data By projecteuclid.org Published On :: Thu, 19 Mar 2020 22:02 EDT Jarno Vanhatalo, Marcelo Hartmann, Lari Veneranta. Source: Bayesian Analysis, Volume 15, Number 2, 415--447.Abstract: Species distribution models (SDM) are a key tool in ecology, conservation and management of natural resources. Two key components of the state-of-the-art SDMs are the description for species distribution response along environmental covariates and the spatial random effect that captures deviations from the distribution patterns explained by environmental covariates. Joint species distribution models (JSDMs) additionally include interspecific correlations which have been shown to improve their descriptive and predictive performance compared to single species models. However, current JSDMs are restricted to hierarchical generalized linear modeling framework. Their limitation is that parametric models have trouble in explaining changes in abundance due, for example, highly non-linear physical tolerance limits which is particularly important when predicting species distribution in new areas or under scenarios of environmental change. On the other hand, semi-parametric response functions have been shown to improve the predictive performance of SDMs in these tasks in single species models. Here, we propose JSDMs where the responses to environmental covariates are modeled with additive multivariate Gaussian processes coded as linear models of coregionalization. These allow inference for wide range of functional forms and interspecific correlations between the responses. We propose also an efficient approach for inference with Laplace approximation and parameterization of the interspecific covariance matrices on the Euclidean space. We demonstrate the benefits of our model with two small scale examples and one real world case study. We use cross-validation to compare the proposed model to analogous semi-parametric single species models and parametric single and joint species models in interpolation and extrapolation tasks. The proposed model outperforms the alternative models in all cases. We also show that the proposed model can be seen as an extension of the current state-of-the-art JSDMs to semi-parametric models. Full Article
i A New Bayesian Approach to Robustness Against Outliers in Linear Regression By projecteuclid.org Published On :: Thu, 19 Mar 2020 22:02 EDT Philippe Gagnon, Alain Desgagné, Mylène Bédard. Source: Bayesian Analysis, Volume 15, Number 2, 389--414.Abstract: Linear regression is ubiquitous in statistical analysis. It is well understood that conflicting sources of information may contaminate the inference when the classical normality of errors is assumed. The contamination caused by the light normal tails follows from an undesirable effect: the posterior concentrates in an area in between the different sources with a large enough scaling to incorporate them all. The theory of conflict resolution in Bayesian statistics (O’Hagan and Pericchi (2012)) recommends to address this problem by limiting the impact of outliers to obtain conclusions consistent with the bulk of the data. In this paper, we propose a model with super heavy-tailed errors to achieve this. We prove that it is wholly robust, meaning that the impact of outliers gradually vanishes as they move further and further away from the general trend. The super heavy-tailed density is similar to the normal outside of the tails, which gives rise to an efficient estimation procedure. In addition, estimates are easily computed. This is highlighted via a detailed user guide, where all steps are explained through a simulated case study. The performance is shown using simulation. All required code is given. Full Article
i Bayesian Bootstraps for Massive Data By projecteuclid.org Published On :: Thu, 19 Mar 2020 22:02 EDT Andrés F. Barrientos, Víctor Peña. Source: Bayesian Analysis, Volume 15, Number 2, 363--388.Abstract: In this article, we present data-subsetting algorithms that allow for the approximate and scalable implementation of the Bayesian bootstrap. They are analogous to two existing algorithms in the frequentist literature: the bag of little bootstraps (Kleiner et al., 2014) and the subsampled double bootstrap (Sengupta et al., 2016). Our algorithms have appealing theoretical and computational properties that are comparable to those of their frequentist counterparts. Additionally, we provide a strategy for performing lossless inference for a class of functionals of the Bayesian bootstrap and briefly introduce extensions to the Dirichlet Process. Full Article
i Dynamic Quantile Linear Models: A Bayesian Approach By projecteuclid.org Published On :: Thu, 19 Mar 2020 22:02 EDT Kelly C. M. Gonçalves, Hélio S. Migon, Leonardo S. Bastos. Source: Bayesian Analysis, Volume 15, Number 2, 335--362.Abstract: The paper introduces a new class of models, named dynamic quantile linear models, which combines dynamic linear models with distribution-free quantile regression producing a robust statistical method. Bayesian estimation for the dynamic quantile linear model is performed using an efficient Markov chain Monte Carlo algorithm. The paper also proposes a fast sequential procedure suited for high-dimensional predictive modeling with massive data, where the generating process is changing over time. The proposed model is evaluated using synthetic and well-known time series data. The model is also applied to predict annual incidence of tuberculosis in the state of Rio de Janeiro and compared with global targets set by the World Health Organization. Full Article
i A Novel Algorithmic Approach to Bayesian Logic Regression (with Discussion) By projecteuclid.org Published On :: Tue, 17 Mar 2020 04:00 EDT Aliaksandr Hubin, Geir Storvik, Florian Frommlet. Source: Bayesian Analysis, Volume 15, Number 1, 263--333.Abstract: Logic regression was developed more than a decade ago as a tool to construct predictors from Boolean combinations of binary covariates. It has been mainly used to model epistatic effects in genetic association studies, which is very appealing due to the intuitive interpretation of logic expressions to describe the interaction between genetic variations. Nevertheless logic regression has (partly due to computational challenges) remained less well known than other approaches to epistatic association mapping. Here we will adapt an advanced evolutionary algorithm called GMJMCMC (Genetically modified Mode Jumping Markov Chain Monte Carlo) to perform Bayesian model selection in the space of logic regression models. After describing the algorithmic details of GMJMCMC we perform a comprehensive simulation study that illustrates its performance given logic regression terms of various complexity. Specifically GMJMCMC is shown to be able to identify three-way and even four-way interactions with relatively large power, a level of complexity which has not been achieved by previous implementations of logic regression. We apply GMJMCMC to reanalyze QTL (quantitative trait locus) mapping data for Recombinant Inbred Lines in Arabidopsis thaliana and from a backcross population in Drosophila where we identify several interesting epistatic effects. The method is implemented in an R package which is available on github. Full Article
i High-Dimensional Posterior Consistency for Hierarchical Non-Local Priors in Regression By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Xuan Cao, Kshitij Khare, Malay Ghosh. Source: Bayesian Analysis, Volume 15, Number 1, 241--262.Abstract: The choice of tuning parameters in Bayesian variable selection is a critical problem in modern statistics. In particular, for Bayesian linear regression with non-local priors, the scale parameter in the non-local prior density is an important tuning parameter which reflects the dispersion of the non-local prior density around zero, and implicitly determines the size of the regression coefficients that will be shrunk to zero. Current approaches treat the scale parameter as given, and suggest choices based on prior coverage/asymptotic considerations. In this paper, we consider the fully Bayesian approach introduced in (Wu, 2016) with the pMOM non-local prior and an appropriate Inverse-Gamma prior on the tuning parameter to analyze the underlying theoretical property. Under standard regularity assumptions, we establish strong model selection consistency in a high-dimensional setting, where $p$ is allowed to increase at a polynomial rate with $n$ or even at a sub-exponential rate with $n$ . Through simulation studies, we demonstrate that our model selection procedure can outperform other Bayesian methods which treat the scale parameter as given, and commonly used penalized likelihood methods, in a range of simulation settings. Full Article
i Learning Semiparametric Regression with Missing Covariates Using Gaussian Process Models By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Abhishek Bishoyi, Xiaojing Wang, Dipak K. Dey. Source: Bayesian Analysis, Volume 15, Number 1, 215--239.Abstract: Missing data often appear as a practical problem while applying classical models in the statistical analysis. In this paper, we consider a semiparametric regression model in the presence of missing covariates for nonparametric components under a Bayesian framework. As it is known that Gaussian processes are a popular tool in nonparametric regression because of their flexibility and the fact that much of the ensuing computation is parametric Gaussian computation. However, in the absence of covariates, the most frequently used covariance functions of a Gaussian process will not be well defined. We propose an imputation method to solve this issue and perform our analysis using Bayesian inference, where we specify the objective priors on the parameters of Gaussian process models. Several simulations are conducted to illustrate effectiveness of our proposed method and further, our method is exemplified via two real datasets, one through Langmuir equation, commonly used in pharmacokinetic models, and another through Auto-mpg data taken from the StatLib library. Full Article
i Determinantal Point Process Mixtures Via Spectral Density Approach By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Ilaria Bianchini, Alessandra Guglielmi, Fernando A. Quintana. Source: Bayesian Analysis, Volume 15, Number 1, 187--214.Abstract: We consider mixture models where location parameters are a priori encouraged to be well separated. We explore a class of determinantal point process (DPP) mixture models, which provide the desired notion of separation or repulsion. Instead of using the rather restrictive case where analytical results are partially available, we adopt a spectral representation from which approximations to the DPP density functions can be readily computed. For the sake of concreteness the presentation focuses on a power exponential spectral density, but the proposed approach is in fact quite general. We later extend our model to incorporate covariate information in the likelihood and also in the assignment to mixture components, yielding a trade-off between repulsiveness of locations in the mixtures and attraction among subjects with similar covariates. We develop full Bayesian inference, and explore model properties and posterior behavior using several simulation scenarios and data illustrations. Supplementary materials for this article are available online (Bianchini et al., 2019). Full Article
i Adaptive Bayesian Nonparametric Regression Using a Kernel Mixture of Polynomials with Application to Partial Linear Models By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Fangzheng Xie, Yanxun Xu. Source: Bayesian Analysis, Volume 15, Number 1, 159--186.Abstract: We propose a kernel mixture of polynomials prior for Bayesian nonparametric regression. The regression function is modeled by local averages of polynomials with kernel mixture weights. We obtain the minimax-optimal contraction rate of the full posterior distribution up to a logarithmic factor by estimating metric entropies of certain function classes. Under the assumption that the degree of the polynomials is larger than the unknown smoothness level of the true function, the posterior contraction behavior can adapt to this smoothness level provided an upper bound is known. We also provide a frequentist sieve maximum likelihood estimator with a near-optimal convergence rate. We further investigate the application of the kernel mixture of polynomials to partial linear models and obtain both the near-optimal rate of contraction for the nonparametric component and the Bernstein-von Mises limit (i.e., asymptotic normality) of the parametric component. The proposed method is illustrated with numerical examples and shows superior performance in terms of computational efficiency, accuracy, and uncertainty quantification compared to the local polynomial regression, DiceKriging, and the robust Gaussian stochastic process. Full Article
i Detecting Structural Changes in Longitudinal Network Data By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Jong Hee Park, Yunkyu Sohn. Source: Bayesian Analysis, Volume 15, Number 1, 133--157.Abstract: Dynamic modeling of longitudinal networks has been an increasingly important topic in applied research. While longitudinal network data commonly exhibit dramatic changes in its structures, existing methods have largely focused on modeling smooth topological changes over time. In this paper, we develop a hidden Markov network change-point model (HNC) that combines the multilinear tensor regression model (Hoff, 2011) with a hidden Markov model using Bayesian inference. We model changes in network structure as shifts in discrete states yielding particular sets of network generating parameters. Our simulation results demonstrate that the proposed method correctly detects the number, locations, and types of changes in latent node characteristics. We apply the proposed method to international military alliance networks to find structural changes in the coalition structure among nations. Full Article
i Bayesian Design of Experiments for Intractable Likelihood Models Using Coupled Auxiliary Models and Multivariate Emulation By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Antony Overstall, James McGree. Source: Bayesian Analysis, Volume 15, Number 1, 103--131.Abstract: A Bayesian design is given by maximising an expected utility over a design space. The utility is chosen to represent the aim of the experiment and its expectation is taken with respect to all unknowns: responses, parameters and/or models. Although straightforward in principle, there are several challenges to finding Bayesian designs in practice. Firstly, the utility and expected utility are rarely available in closed form and require approximation. Secondly, the design space can be of high-dimensionality. In the case of intractable likelihood models, these problems are compounded by the fact that the likelihood function, whose evaluation is required to approximate the expected utility, is not available in closed form. A strategy is proposed to find Bayesian designs for intractable likelihood models. It relies on the development of an automatic, auxiliary modelling approach, using multivariate Gaussian process emulators, to approximate the likelihood function. This is then combined with a copula-based approach to approximate the marginal likelihood (a quantity commonly required to evaluate many utility functions). These approximations are demonstrated on examples of stochastic process models involving experimental aims of both parameter estimation and model comparison. Full Article
i Bayesian Network Marker Selection via the Thresholded Graph Laplacian Gaussian Prior By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Qingpo Cai, Jian Kang, Tianwei Yu. Source: Bayesian Analysis, Volume 15, Number 1, 79--102.Abstract: Selecting informative nodes over large-scale networks becomes increasingly important in many research areas. Most existing methods focus on the local network structure and incur heavy computational costs for the large-scale problem. In this work, we propose a novel prior model for Bayesian network marker selection in the generalized linear model (GLM) framework: the Thresholded Graph Laplacian Gaussian (TGLG) prior, which adopts the graph Laplacian matrix to characterize the conditional dependence between neighboring markers accounting for the global network structure. Under mild conditions, we show the proposed model enjoys the posterior consistency with a diverging number of edges and nodes in the network. We also develop a Metropolis-adjusted Langevin algorithm (MALA) for efficient posterior computation, which is scalable to large-scale networks. We illustrate the superiorities of the proposed method compared with existing alternatives via extensive simulation studies and an analysis of the breast cancer gene expression dataset in the Cancer Genome Atlas (TCGA). Full Article
i Bayesian Estimation Under Informative Sampling with Unattenuated Dependence By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Matthew R. Williams, Terrance D. Savitsky. Source: Bayesian Analysis, Volume 15, Number 1, 57--77.Abstract: An informative sampling design leads to unit inclusion probabilities that are correlated with the response variable of interest. However, multistage sampling designs may also induce higher order dependencies, which are ignored in the literature when establishing consistency of estimators for survey data under a condition requiring asymptotic independence among the unit inclusion probabilities. This paper constructs new theoretical conditions that guarantee that the pseudo-posterior, which uses sampling weights based on first order inclusion probabilities to exponentiate the likelihood, is consistent not only for survey designs which have asymptotic factorization, but also for survey designs that induce residual or unattenuated dependence among sampled units. The use of the survey-weighted pseudo-posterior, together with our relaxed requirements for the survey design, establish a wide variety of analysis models that can be applied to a broad class of survey data sets. Using the complex sampling design of the National Survey on Drug Use and Health, we demonstrate our new theoretical result on multistage designs characterized by a cluster sampling step that expresses within-cluster dependence. We explore the impact of multistage designs and order based sampling. Full Article
i The Bayesian Update: Variational Formulations and Gradient Flows By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Nicolas Garcia Trillos, Daniel Sanz-Alonso. Source: Bayesian Analysis, Volume 15, Number 1, 29--56.Abstract: The Bayesian update can be viewed as a variational problem by characterizing the posterior as the minimizer of a functional. The variational viewpoint is far from new and is at the heart of popular methods for posterior approximation. However, some of its consequences seem largely unexplored. We focus on the following one: defining the posterior as the minimizer of a functional gives a natural path towards the posterior by moving in the direction of steepest descent of the functional. This idea is made precise through the theory of gradient flows, allowing to bring new tools to the study of Bayesian models and algorithms. Since the posterior may be characterized as the minimizer of different functionals, several variational formulations may be considered. We study three of them and their three associated gradient flows. We show that, in all cases, the rate of convergence of the flows to the posterior can be bounded by the geodesic convexity of the functional to be minimized. Each gradient flow naturally suggests a nonlinear diffusion with the posterior as invariant distribution. These diffusions may be discretized to build proposals for Markov chain Monte Carlo (MCMC) algorithms. By construction, the diffusions are guaranteed to satisfy a certain optimality condition, and rates of convergence are given by the convexity of the functionals. We use this observation to propose a criterion for the choice of metric in Riemannian MCMC methods. Full Article
i Scalable Bayesian Inference for the Inverse Temperature of a Hidden Potts Model By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Matthew Moores, Geoff Nicholls, Anthony Pettitt, Kerrie Mengersen. Source: Bayesian Analysis, Volume 15, Number 1, 1--27.Abstract: The inverse temperature parameter of the Potts model governs the strength of spatial cohesion and therefore has a major influence over the resulting model fit. A difficulty arises from the dependence of an intractable normalising constant on the value of this parameter and thus there is no closed-form solution for sampling from the posterior distribution directly. There is a variety of computational approaches for sampling from the posterior without evaluating the normalising constant, including the exchange algorithm and approximate Bayesian computation (ABC). A serious drawback of these algorithms is that they do not scale well for models with a large state space, such as images with a million or more pixels. We introduce a parametric surrogate model, which approximates the score function using an integral curve. Our surrogate model incorporates known properties of the likelihood, such as heteroskedasticity and critical temperature. We demonstrate this method using synthetic data as well as remotely-sensed imagery from the Landsat-8 satellite. We achieve up to a hundredfold improvement in the elapsed runtime, compared to the exchange algorithm or ABC. An open-source implementation of our algorithm is available in the R package bayesImageS . Full Article