f [ASAP] Inhibitors of Hypoxia-Inducible Factors as Treatment for Cancer By feedproxy.google.com Published On :: Wed, 01 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00116 Full Article
f [ASAP] Glycans Meet Sphingolipids: Structure-Based Design of Glycan Containing Analogues of a Sphingosine Kinase Inhibitor By feedproxy.google.com Published On :: Wed, 01 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00665 Full Article
f [ASAP] Therapeutic Potential of Targeted Nanoparticles and Perspective on Nanotherapies By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00075 Full Article
f [ASAP] Synthesis of Novel G Factor or Chloroquine-Artemisinin Hybrids and Conjugates with Potent Antiplasmodial Activity By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00669 Full Article
f [ASAP] Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00045 Full Article
f [ASAP] Escaping from Flatland: Substituted Bridged Pyrrolidine Fragments with Inherent Three-Dimensional Character By feedproxy.google.com Published On :: Thu, 02 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00039 Full Article
f [ASAP] Characterization of an Alginate Encapsulated LS180 Spheroid Model for Anti-colorectal Cancer Compound Screening By feedproxy.google.com Published On :: Fri, 03 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00076 Full Article
f [ASAP] Structure Optimization of Gatastatin for the Development of ?-Tubulin-Specific Inhibitor By feedproxy.google.com Published On :: Mon, 06 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00526 Full Article
f [ASAP] Chiral Analogues of PFI-1 as BET Inhibitors and Their Functional Role in Myeloid Malignancies By feedproxy.google.com Published On :: Tue, 07 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00625 Full Article
f [ASAP] Rationally Designed Covalent BCL6 Inhibitor That Targets a Tyrosine Residue in the Homodimer Interface By feedproxy.google.com Published On :: Tue, 07 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00111 Full Article
f [ASAP] Assembling Pharma Resources to Tackle Diseases of Underserved Populations By feedproxy.google.com Published On :: Wed, 08 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00051 Full Article
f [ASAP] Pharmacophore-Based Virtual Screening for Identification of Negative Modulators of GLI1 as Potential Anticancer Agents By feedproxy.google.com Published On :: Wed, 08 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00639 Full Article
f [ASAP] Exploring the Implication of DDX3X in DENV Infection: Discovery of the First-in-Class DDX3X Fluorescent Inhibitor By feedproxy.google.com Published On :: Thu, 09 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00681 Full Article
f [ASAP] Discovery of BMS-986251: A Clinically Viable, Potent, and Selective ROR?t Inverse Agonist By feedproxy.google.com Published On :: Fri, 10 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00063 Full Article
f [ASAP] Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction By feedproxy.google.com Published On :: Fri, 10 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00594 Full Article
f [ASAP] Selective Covalent Targeting of Mutated EGFR(T790M) with Chlorofluoroacetamide-Pyrimidines By feedproxy.google.com Published On :: Fri, 10 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00574 Full Article
f [ASAP] Design and Synthesis of Tetrazole- and Pyridine-Containing Itraconazole Analogs as Potent Angiogenesis Inhibitors By feedproxy.google.com Published On :: Mon, 13 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00438 Full Article
f [ASAP] Potential Cancer Treatment by Agonists of the Stimulator of Interferon Genes By feedproxy.google.com Published On :: Mon, 13 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00117 Full Article
f [ASAP] Artemisinin Derivatives with Antimelanoma Activity Show Inhibitory Effect against Human DNA Topoisomerase 1 By feedproxy.google.com Published On :: Tue, 14 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00131 Full Article
f [ASAP] Complete Regression of Carcinoma via Combined C-RAF and EGFR Targeted Therapy By feedproxy.google.com Published On :: Tue, 14 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00159 Full Article
f [ASAP] Discovery of a Potent Dual Inhibitor of Wild-Type and Mutant Respiratory Syncytial Virus Fusion Proteins By feedproxy.google.com Published On :: Wed, 15 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00008 Full Article
f [ASAP] Characterization of Specific <italic toggle="yes">N</italic>-a-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library By feedproxy.google.com Published On :: Wed, 15 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00029 Full Article
f [ASAP] Discovery of an Atropisomeric PI3Kß Selective Inhibitor through Optimization of the Hinge Binding Motif By feedproxy.google.com Published On :: Wed, 15 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00095 Full Article
f [ASAP] Discovery of CPI-1612: A Potent, Selective, and Orally Bioavailable EP300/CBP Histone Acetyltransferase Inhibitor By feedproxy.google.com Published On :: Mon, 27 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00155 Full Article
f [ASAP] PROTAC Compounds Targeting a-Synuclein Protein for Treating Neurogenerative Disorders: Alzheimer’s and Parkinson’s Diseases By feedproxy.google.com Published On :: Tue, 28 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00192 Full Article
f [ASAP] Development of Selective Steroid Inhibitors for the Glucose-6-phosphate Dehydrogenase from <italic toggle="yes">Trypanosoma cruzi</italic> By feedproxy.google.com Published On :: Wed, 29 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00106 Full Article
f [ASAP] Discovery of RO7185876, a Highly Potent ?-Secretase Modulator (GSM) as a Potential Treatment for Alzheimer’s Disease By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00109 Full Article
f [ASAP] Ultra-High-Throughput Acoustic Droplet Ejection-Open Port Interface-Mass Spectrometry for Parallel Medicinal Chemistry By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00066 Full Article
f [ASAP] Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00025 Full Article
f [ASAP] Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00092 Full Article
f [ASAP] Scaffold Repurposing of in-House Chemical Library toward the Identification of New Casein Kinase 1 d Inhibitors By feedproxy.google.com Published On :: Mon, 04 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00028 Full Article
f [ASAP] Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00009 Full Article
f [ASAP] Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin-1 Antagonists: Discovery of JNJ-54717793 By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00085 Full Article
f [ASAP] De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00022 Full Article
f [ASAP] Synthesis and Evaluation of <sup>11</sup>C- and <sup>18</sup>F-Labeled SOAT1 Inhibitors as Macrophage Foam Cell Imaging Agents By feedproxy.google.com Published On :: Wed, 06 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00127 Full Article
f [ASAP] Ligand Design for Cereblon Based Immunomodulatory Therapy By feedproxy.google.com Published On :: Fri, 08 May 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00214 Full Article
f Germany Facing Mass Blackouts Because The Wind And Solar Won’t Cooperate By latestsolarnews.com Published On :: Sat, 04 Mar 2017 19:59:09 +0000 Germany’s energy network nearly broken down in January because of poor execution from wind turbines and sun based boards, as indicated by information from a noteworthy exchange union. Wind and sunlight based power plants failed to meet expectations in January, 2017, as a result of shady climate with almost no wind, setting the phase for … The post Germany Facing Mass Blackouts Because The Wind And Solar Won’t Cooperate appeared first on LatestSolarNews. Full Article News
f Solar Trees Powering The Park Of South Florida By latestsolarnews.com Published On :: Sun, 23 Jul 2017 23:58:07 +0000 Joining South Florida’s lush, green canopy of real trees are a new crop of solar trees. These “trees” have blue trunks and bear no fruit, but supply clean energy to whoever needs it. If you’re at the beach and your phone starts to die, you can charge it right here using Solar Power. Here’s how … The post Solar Trees Powering The Park Of South Florida appeared first on LatestSolarNews. Full Article News
f Solar Powered Lights For The Yard By latestsolarnews.com Published On :: Wed, 26 Jul 2017 21:41:45 +0000 Reading about the various sofas reviews here and choosing amongst them to match your patio is not that difficult when compared to doing the entire electrical work of the patio. When you are lighting your patio the exact opposite thing you need to do is to be stumbling over electrical lines and attempting to put … The post Solar Powered Lights For The Yard appeared first on LatestSolarNews. Full Article installations Why Solar
f 4 Benefits Of Solar LED Lights For Parking Lots By latestsolarnews.com Published On :: Sun, 08 Jul 2018 21:32:34 +0000 The future is solar LED lights. You will see them in the parking lots and other large areas around a city. They are cheap and save a good deal of money on electricity bills. Nowadays, the majority of parking lots feature the conventional lights that get their power from the grid. These products are not … The post 4 Benefits Of Solar LED Lights For Parking Lots appeared first on LatestSolarNews. Full Article Power Generation
f India is planning to achieve 50 GW of prodction from renewbale energy by 2028 By latestsolarnews.com Published On :: Tue, 08 Jan 2019 10:08:19 +0000 India is planning to achieve 50 gigawatt (GW) of production from renewable energy by 2028, in order to get to its goal of 40 per cent of electricity generation from non-fossil fuels by 2030, Ministry of New and Renewable Energy secretary, Anand Kumar said at the India-Norway Business Summit 2019 in New Delhi. Of this … The post India is planning to achieve 50 GW of prodction from renewbale energy by 2028 appeared first on LatestSolarNews. Full Article News india solar energy india
f Filtering (photo) filters By simurai.com Published On :: Sun, 20 Jul 2014 00:00:00 +0000 A lot of photo apps allow you to add filters before sharing. The typical UI for picking a filter is a row of little thumbnails that can be horizontally scrolled. I’m sure you’ve used it many times. It looks something like this: The problem A filter picker like that is easy to understand and works pretty well. But in my case, there is something that has been bugging me a bit. Here is how I use it: I start with the first thumbnail and then just keep tapping one after the other. If there is a filter that I like, I try to remember its name. And somewhat its position, but more like “somewhere at the beginning”. Then once I reach the end, I start scrolling back trying to find the ones I liked. Usually there are like 2-3 filters that I would like to quickly compare before making my final choice. But it’s quite hard to scroll between them, especially if they are far apart. Also having to remember their name/position costs some precious brain power. Now, I don’t really know how most people use these filter pickers. Could be that: Most people just stop once they found a filter they kinda like and don’t bother trying the rest. Or some have a few favorites and know their name/position already. You could also just look at the little thumbnails. But some filters are very similar and I need to see them on the actual photo to judge. Possible solutions So I was thinking about some possible improvements: 1. Order by popularity Automatically order the filters based on how often they get used. This makes filters that you use most appear at the beginning and are easier to get to. You could always keep scrolling in case you’re in the mood for something new. This would of course mess it up for people that have filters remembered by position. But not sure how many actually do that. 2. Manual re-order Let people manually reorder the position. Could be done similar like the home screen icons on iOS (long press until they wiggle, then drag around). I would probably move my favorites to the front and also sort based on color/style. 3. Narrow down Let people temporarily toss away the filters they don’t want. This would allow you to narrow down your selection to just a few for easier comparison. Of course, all the filters would be back next time you take a new photo. Or probably even better (3B): Instead of throwing away the ones you don’t like (could be tedious if there are a lot of filters), you could push up only the ones you like and they would move to the right with a visual separator. It’s similar how you can pin a Chrome browser tab to separate it from the rest. Then once you scrolled to the end, you would have all your previously selected filters next to each other, waiting to be the lucky winner. Conclusion I understand that the suggestions might make a photo app more complicated and harder to explain to a new user. But it could be more a “power user” feature that you’re not forced to use if you don’t want to. Anyways, in case I’m not the only one with this (small) problem, I hope some day we will have a better way to filter filters. Ohh.. and let me know if you’re already using an app that tackles this somehow. Update Thanks for all the comments. Good to see more people thinking about this. I played around a bit more with the demo, mostly after the conversation with Ignacio in the comments below. So here a 4th option: 4. Select and cycle Let people select a couple filters and then cycle through them by tapping on the photo. It’s actually similar to 3B, but it keeps the UI simple by using the photo as the secondary navigation control. Here the steps how to use: You can tab each filter until you find one you like. If you tab a 2nd time on that filter, it gets selected as a “favorite”. It will move up a little to visualize it. You can keep trying other filters and mark more as favorites. Once you reached the end (or think you have enough), you can tap on the photo above the filter picker to quickly cycle through all your previously selected (favorited) filters. Now comparing different filters is really quick and easy. Try the demo. The implementation of the demo could still be improved. It is a bit hard to discover that you can tap the photo to cycle through your favorites. Might need some visual clue to help understand it better. Adding swipe gestures instead of tapping would also improve UX. Or to remove a filter from your favorite selection, you could just swipe down on the image. Also note that the filters are CSS based and still a bit glitchy when animating. But you should get the idea. Update II Manuel Haring explored a similar concept where you can push up filters to narrow down your selection. Here a larger video that has even a third selection stage. Full Article
f FrontLinks By simurai.com Published On :: Wed, 01 Oct 2014 00:00:00 +0000 This is my (living) collection of front-end links. It’s not complete by all means, in fact, there isn’t any of the obvious ones, like Can I use or so. Just some links that I need occasionally but can’t remember their names, so I saved them here for quick access. Also, they’re somewhat randomly ordered. Note to self: Edit source Docs HTML reference DevDocs Native HTML Elements jQuery -> JS Default Font Family Shadow DOM The list Form Pseudo Elements Device sizes SVG PocketGuide CSS CSS reference All CSS properties All CSS values CSS Triggers (perf) Stats StyleStats CSS Stats CSS Preprocessors Roole CSS to SCSS FlexBox cheatsheet Flexbox Playground Patterns Flexbox in 5min Flexplorer FlexyBoxes Animation Bounce.js Stylie Easing: Bezier Builder Ceaser cubic-bezier Easings nth-child nth-test :kids Color Color converter Contrast tester Clip Path px to em Cursors Live Edit Takana Emmet Libs + Frameworks Web Starter Kit vue.js Physics Animation AniJS Popmotion Utils + Tools Wireframes Whimsical wireframe.cc Moqups HTML symbols ☺ Characters Draw Chars Placeholder Image FavIcon Editor SVG SVG Optimizer Paths (editor) GitHub Editor Resources Color schemes Fonts Font Guide Tagged Google Fonts Blokk Font Icons Feather Icomoon Material Entypo Photos SplashBase Stock Up Unsucky Stock Photos Subtle Patterns UI Sounds Full Article
f 17 Tools for Effective Customer Engagement By www.webdesignerdepot.com Published On :: Thu, 23 Apr 2020 10:45:09 +0000 The one thing that every business that offers a service has in common is its customers. It doesn't matter if you are a freelancer with just one client or a small design agency with a few clients, you have to deal with customers on a day to day basis. Full Article Tools & Resources client surveys customer feedback apps customer relations tools customer service apps customer surveys
f Popular Design News of the Week: April 20, 2020 – April 26, 2020 By www.webdesignerdepot.com Published On :: Sun, 26 Apr 2020 10:45:05 +0000 Every week users submit a lot of interesting stuff on our sister site Webdesigner News, highlighting great content from around the web that can be of interest to web designers. The best way to keep track of all the great stories and news being posted is simply to check out the Webdesigner News site, however, […] Full Article News Adobe Apps Best Of Compilation CSS Design Fonts Freelancing Google Graphic Design Humor Inspiration responsive design Social Media Typography Usability ux design Web Design Web Development
f The Latest Research for Web Designers, April 2020 By www.webdesignerdepot.com Published On :: Mon, 27 Apr 2020 10:45:10 +0000 Although life hasn’t returned to normal yet, the web design and marketing space doesn’t seem to have been too badly disrupted — at least not with all the new research and surveys floating around. And thank goodness for that. If we can maintain some semblance of normalcy, I think we’ll all get through this crisis in good shape. Full Article Business & Tech cybersecurity design research ecommerce marketing technical seo web design facts web design research
f 8 Best CMS for 2020 By www.webdesignerdepot.com Published On :: Fri, 01 May 2020 10:45:36 +0000 Content Management Systems are arguably the internet’s most powerful web development tool. In a rapidly growing market where every business under the sun requires a website that is not only fully functioning, but optimised, easy to update regularly, and implement the latest features, the right CMS is important. As a web developer it can be […] Full Article Tools & Resources Concrete5 Craft Flextype joomla Magnolia MotoCMS Umbraco Vapid
f Popular Design News of the Week: April 27, 2020 – May 3, 2020 By www.webdesignerdepot.com Published On :: Sun, 03 May 2020 10:45:45 +0000 Every week users submit a lot of interesting stuff on our sister site Webdesigner News, highlighting great content from around the web that can be of interest to web designers. The best way to keep track of all the great stories and news being posted is simply to check out the Webdesigner News site, however, […] Full Article News Apps Best Of Compilation CSS Design Fonts Freelancing Google Graphic Design illustration Inspiration responsive design Social Media Typography Usability ux design Web Design Web Development
f 8 of the Top WP Multipurpose Themes That You Can Use By www.webdesignerdepot.com Published On :: Tue, 05 May 2020 10:45:00 +0000 More than a few multipurpose WordPress themes have become big sellers in recent years, and for a reason. Actually, for several reasons. One reason is they serve as excellent toolkits for web designers who have large and varied clienteles. The best multipurpose themes, like those presented here, are popular for other reasons as well. They […] Full Article Sponsored Best WordPRess themes BeTheme Top WP themes Total WordPress Theme Wordpress Themes
f Hockey | HI asks for bids to host various Nationals By www.thehindu.com Published On :: Tue, 05 May 2020 22:53:48 +0530 State units can take part across age-groups Full Article Hockey