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Up-regulation of myelin-associated glycoprotein is associated with the ameliorating effect of omega-3 polyunsaturated fatty acids on Alzheimer's disease progression in APP–PS1 transgenic mice

Food Funct., 2024, 15,11236-11251
DOI: 10.1039/D4FO03355H, Paper
Yan Shao, Fei Li, Bo Zou, Yanling Jin, Xiaoyang Wang, Liting Wang, Youying Huang, Yu Xie, Wei Sun, Jing X. Kang, Kai Liu, Yi Huang, Wei Huang, Bin Wang
Our study showed that MAG upregulation might be the new regulatory mechanism for omega-3 PUFAs to exert AD protective effects, which is helpful for expanding our understanding of the health-promoting effects of omega-3 PUFAs.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Mechanistic insights into EGCG's preventive effects on obesity-induced precocious puberty through multi-omics analyses

Food Funct., 2024, 15,11169-11185
DOI: 10.1039/D4FO03844D, Paper
Qiuyun Gu, Qiujv Du, Lina Xia, Xiaoting Lu, Xiaoqing Wan, Ying Shao, Jieyi He, Peiying Wu
Epigallocatechin gallate (EGCG) has demonstrated potential effects on obesity-induced precocious puberty, but the underlying mechanisms remain unclear.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Letters to the Editor dated October 25, 2024 




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Philip's Review

Philip's is a light-hearted film you can enjoy with your family and safely recommend to your friends, endorses Divya Nair.




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Big Girls Don't Cry Review

Big Girls Don't Cry is too solemn to be fun and too timid to be truly bold, feels Deepa Gahlot.




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Mr & Mrs Mahi Review

I liked how the film finds excitement in Mahendra and Mahima's dull lives and transforms their humdrum existence into an ode to second chances, notes Sukanya Verma.




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Deadpool & Wolverine Review

Deadpool & Wolverine is an example of confident film-making and unbridled enthusiasm to show what the Deadpool franchise means for its fans, observes Mayur Sanap.




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Ananya's CTRL Must Be On Your Watchlist

While several international films and Web series on the OTT have explored the dangers of AI, it's interesting to see a desi take on it, believes Divya Nair.




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Farmers in Punjab block highways in protest against 'tardy' paddy procurement




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A hundred years ago | Everest expedition




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Mumbai thrash Bengal by 10 wickets, win Senior Women's T20 Trophy

In a one-sided contest played at the Wankhede Stadium, Mumbai shot out Bengal for a meagre 85 in 20 overs and got over the line unscathed to make 86 for no loss in 12.3 overs.




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China, Russia must fight U.S. 'containment': security chief




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Remembering Suryakumari, the woman who immortalised ‘Ma Telugu Thalli ki’ with her voice

The neice of Tanguturi Prakasam Pantulu brought much popularity to the song written by Sankarambadi Sundarachari




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Chaavadikota hill, the newest destination in Maredumilli forests beckons tourists 

With its breathtaking sunrise and sunset views, and pristine waterfalls, the emerging destination offers a treat to nature lovers, and a possibility to experience the hospitality of the aboriginal tribes




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EC asks police to register case against Anvar 




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Booker Prize 2024: British writer Samantha Harvey wins for space-station novel 'Orbital'

She called the book a “space pastoral” about six astronauts circling the Earth, which she began writing during COVID-19 pandemic lockdowns




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FIR filed against producers of Yash-starrer Toxic 




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Goods train derails in Telangana's Peddapalli; 20 trains cancelled, 10 diverted

Eleven wagons of the goods train carrying iron ore derailed between Raghavapuram and Ramagundam








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Why can't we create a Big Bang Theory?

'Where are the funny writers on Indian television and OTT platforms?''Where are the sitcoms?' asks Vanita Kohli Khandekar.





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Bollywood's biggest bane isn't nepotism

'Sushant Singh Rajput, a bright young lad who had a life beyond films, was probably too good for Bollywood.''To blame his death by suicide on a gang of Bollywood bullies is stretching the point too far,' argues Saibal Chatterjee.





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There won't be a James Bond like Sean Connery

As dry as the martini Bond enjoyed, Connery's 007 was a <em>tour de force</em> of comicbook heroism replete with set pieces and choreographed stunts which he carried off with a Scottish virility, notes Subhash K Jha.




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Salute the Power &amp; Glory of Indian Cinema!

It is the most potent symbol of India's soft power -- more perhaps than the IT industry and our managerial skill, notes Vanita Kohli-Khandekar




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Oscar nod or not, Jallikattu's selection is a win-win

The Oscars is prestigious and all artists covet it but ultimately, the business of winning is ruthless and political. And India has seldom risen to the challenge, argues Sukanya Verma.









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'Sanju remembers her only for the love'

'I don't think my troubles would have happened if she was with me. I kind of lost my way after she was gone,' Sanjay Dutt once told Subhash K Jha about his mother Nargis, the legendary actress who passed away this day 41 years ago.




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Is Jaideep Ahlawat India's Finest Actor?

If Irrfan could have been our finest professor of empirical philosophy, and Nawaz is our foremost poet of that space halfway between the gutter and the stars, then Jaideep Ahlawat has to be our greatest artist-scientist, asserts Sreehari Nair.




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The Small Big Pictures Of Rajamouli &amp; Co

RRR isn't the "spectacle" it is made out to be, argues Sreehari Nair.




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'Difficult to keep up with Ranveer'

Ranveer is loud, but not shrill, notes Subhash K Jha.As in singing, in acting holding your pitch in the higher notes is a Himalayan task.Ranveer resides on the highest notes of the musical mountain and still manages to be coherent, fluent and persuasive.




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Lijo Jose Pellissery's Women And Mine

Pellissery's women continue to express the beauty in our common humanity. And often, these women go so far into expressing our hopes, desires, absurdities and follies that they end up acting at variance with the ethical prescriptions of our age. And this, I believe, is precisely why they remain "invisible" to a whole bunch of viewers, says Sreehari Nair.




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Why Didn't #BoycottBrahmastra Work?

Nobody else needs to boycott Bollywood, they are doing a pretty good job of digging up their own foundation, notes Deepa Gahlot.




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Why Lataji Didn't Sing With Rafi, SD...

Long before she won royalty rights for playback singers, there was an undisclosed incident in Lataji's life where she not only put a male colleague in place, but also refused to sing with him thereafter.




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Keeravaani's Gracious Act At Globes

The composer thanked other artists for the making of the song.




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Pathaan Is About Shah Rukh's Life

More than anything else, Pathaan is a silent and subtle statement of Shah Rukh Khan about his place, his commitment to cinema and, if one can say, his politics, observes Mohammad Asim Siddiqui.




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When Pathaan's Villain Made You Think

Let us get high on Pathaan and his simple-minded antics, sure, but let us also take a moment to think about Jim who, with that one cunning piece of dialogue, goes on to boldly state that patriotism is a many-hued thing, observes Sreehari Nair.




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Why 2018 Is The 'Real' Kerala Story

Kindness and compassion is all you need to survive and build your life. And that is what makes 2018's Kerala story so relevant, notes Divya Nair.




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Did This Destroy Raakhee's Marriage?

As Independent India turned 76, so did the ethereal Raakhee I know better than most, says Subhash K Jha.




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Gulzar's Madhur Dosti With R D Burman

None of R D Burman's collaborations was as rewarding and resplendent as with Gulzar, who turns 89 today, August 18, 2023, says Subhash K Jha.




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You Know What's Sadder Than National Film Awards?

We are back to being a country that talks about box office numbers as the measure for what an audience's real feelings about a movie are, laments Sreehari Nair.




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'How Can Truth Hurt The Film-maker?'

As Mahesh Bhatt turns 75 on September 20, Subhash K Jha calls him the 'eternal seeker of truth in cinema and in life'.




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Our Biopics Are Bad, But There's Hope

I do have a dream biopic. It has as its subject Renu Saluja, the cosmically gifted editor, with a special focus on the Vidhu Vinod Chopra-Saluja-Sudhir Mishra love story, says Sreehari Nair.