The invention concerns soluble and antigenic HTLV p24 variants that can be fused to chaperones and their use in diagnostic applications such as immunoassays for detecting antibodies against HTLV-I or HTLV-II in an isolated biological sample. In particular, the invention relates to a soluble HTLV-I or HTLV-II p24 antigen comprising either the N- or the C-terminal domain of p24 and lacking the other domain. Moreover, the invention covers recombinant DNA molecules encoding these HTLV-I and -II fusion antigens as well as their recombinant production using expression vectors and host cells transformed with such expression vectors. In addition, the invention focuses on compositions of these HTLV p24 antigens with HTLV gp21 antigen and on an immunoassay method for detection of HTLV antibodies using the antigens of the invention. Also the use of HTLV p24 antigens in an in vitro diagnostic assay as well as a reagent kit for detection of anti-HTLV-antibodies comprising said HTLV antigens is encompassed.

The present invention relates to in vitro methods of assessing the susceptibility or responsiveness of a subject to the treatment with an epidermal growth factor receptor (EGFR) inhibitor/antagonist, wherein the subject has been diagnosed or suspected of suffering from inflammation-associated. These methods comprise determining the level of expression of EGFR in myeloid cells in a sample from the subject, wherein an expression of EGFR in the myeloid cells is indicative of the subject being susceptible to the treatment with an EGFR inhibitor/antagonist. The invention also relates to EGFR inhibitors/antagonists for use in the treatment or amelioration of inflammation-associated cancer. The invention furthermore provides in vitro methods of prognosing the survival time, progression-free survival time or disease course of a subject that has been diagnosed or suspected of suffering from from inflammation-associated cancer. In addition thereto, the invention relates to in vitro diagnostic methods of assessing the proneness of a subject to develop inflammation-associated cancer in which the expression of EGFR is determined in myeloid cells from the subject.

A system and method for detecting a biomarker in exhaled breath condensate nanodroplets comprises noninvasively collecting exhaled breath condensate nanodroplets of a subject, and analyzing said nanodroplets utilizing immuno-quantitative polymerase chain reaction to detect one or more target biomarkers.

The present invention relates to methods of determining if a subject has an increased risk of suffering from memory impairment. The methods comprise analyzing at least one sample from the subject to determine a value of the subject's exosomal profile or combined biomarker profile (lipids plus exosomal cargo) and comparing the value of the subject's exosomal or combined biomarker profile with the value of a normal exosomal or biomarker profile, respectively. A change in the value of the subject's exosomal or combined biomarker profile, including a change in the subject's exosomal or combined biomarker profile, over normal values is indicative that the subject has an increased risk of suffering from memory impairment compared to a normal individual.

East Bay resident Miles Woodruff, CEO of the pioneering vegan-seafood brand Sophie's Kitchen, has just donated 3,000 cases of plant-based Toona to the Food Bank of Contra Costa and Solano County as well as several other Bay Area food shelters.

Amidst the Covid-19 outbreak, the company's brand-new Lemon Grass Toona flavor has not yet arrived in grocery stores — but 100 percent of it is now being provided to people in need.…

This month alone, Oakland-based, family-owned Mr. Espresso has already donated over 2,500 pounds of coffee to COVID-19 relief efforts all over the Bay Area.

During the first two weeks of April, the 42-year-old company — founded in Alameda by enterprising Italian-born Carlo Di Ruocco and now renowned as the first and currently only outfit in the nation that uses oak wood to roast its beans — has given coffee to the Alameda County Community Food Bank and San Francisco-Marin Food Bank, Frontline Foods, East Bay FeedER, Clinica de La Raza, St. Anthony’s Dining Room, Loaves and Fishes Family Kitchen, and other food-, health-, homeless-, youth-, and family-assistance programs.…

A method and system for cooling a device (preferably a micro-device), comprising cooling the device by using a lower critical solution temperature (LCST) mixture. Enhancement of heat transfer rates is achieved during phase separation of a two-component system (two-component mixture) with a LCST. Convective heat transfer rates in small diameter pipes and over a vertical (hot) plate are demonstrated.

An SSD with a package optimized for semiconductor wafers is configured by thinning a plurality of undiced wafers and stacking the wafers. The wafers are connected to each other by TSV. A subset of the wafers include memory circuits. One of the wafer not in the subset includes peripheral circuits. A casing houses the wafers.

Provided herein is a resin fluxed solder paste that exhibits a desirable solder bump reinforcement effect without requiring an underfill process. The disclosure also provides a mount structure. The resin fluxed solder paste includes a non-resinic powder containing a solder powder and an inorganic powder; and a flux containing a first epoxy resin, a curing agent, and an organic acid. The non-resinic powder accounts for 30 to 90 wt % of the total, and the surface of the inorganic powder is covered with an organic resin.

I was wondering why the iconic Civic Centre clock in Southampton is not lit up blue on Thursday at 8pm to clap for the NHS.

If you haven’t looked at Traktor DJ, Native Instruments’ iOS app (it runs on Mac and PC too) recently, a new update and the concurrent global stay-home happening seems like the perfect time to do it. The update to Traktor DJ 2.4 has a bunch of features that look like they’re straight out of a […]

The post Traktor DJ 2.4: Transport Control UI Improvements, Genre Sorting appeared first on DJ TechTools.

The provocative A Human Ounce at Central Works asks whether the creator can be separate from the creation. Central Works opens its 30th anniversary season with A Human Ounce, a new play by Nicole Parizeau that poses provocative questions. What is the value of great art, literature, music, commerce, scientific discovery — even Peet's coffee — when scandalous information about its creators or owners comes to light?…

A reading list specifically appropriate to these trying times. Okay, you're stuck in the house, but is it really that awful? OK, probably.…

Buy it From Local Stores Harvard Business School professor Ryan Raffaelli describes the unique value that independent booksellers provide to local economies in this way: "It's about community, it's about curation and it's about convenience." Author of a working paper titled, "Reinventing Retail: The Novel Resurgence of Independent Bookstores," Raffaelli argues that in focusing on the "Three Cs" of community, curation, and convenience, independent booksellers have regained their footing in the face of competition from big chains and Amazon and enjoyed a resurgence in recent years.…

The invention relates to a storage tank (1) in a motor vehicle for receiving an aqueous urea solution for the SCR of nitrogen oxide in the exhaust gas. The storage tank (1) comprises a tank body which forms a storage volume (2) for the urea solution. The storage tank (1) furthermore comprises a filling pipe for filling the storage volume (2) and means for venting the storage volume (2) during the refuelling, wherein the filling pipe (3) has a filling head (9) at a remote end, and the filling head (9) forms an orifice stub (10). The orifice stub (10) defines an orifice (11) for receiving a fuel pump nozzle. Said orifice stub furthermore has an external thread for receiving a complementary union thread of a refuelling cylinder for refuelling by the gas displacement method. The orifice stub forms at least one secondary air opening when the refuelling cylinder is attached, and therefore, when a refuelling cylinder is attached, a sealing seat is bridged by the refuelling cylinder and refuelling by the gas displacement method is possible even if counterflow venting through the filling tube (3) does not take place.

A sensor mounting table for mounting sensors to an aftertreatment system may include a sensor mounting plate having a substantially flat mounting surface for mounting one or more sensors associated with the aftertreatment system. The substantially flat mounting surface may be offset from a heat shield of the aftertreatment system. The sensor mounting table may further include an insulative material disposed between at least a portion of the substantially flat mounting surface of the sensor mounting plate and the heat shield. The sensor mounting plate may be configured to be attached to the aftertreatment system to secure the insulative material between the substantially flat mounting surface of the sensor mounting plate and the heat shield.

A gas turbine engine cooling system includes a gas turbine engine. The gas turbine engine includes a core engine, a cold sink, a core undercowl space, and a core cowl at least partially surrounding the core engine and defining a radially outer wall of the core undercowl space. The gas turbine engine cooling system includes an undercowl component positioned in the core undercowl space. The gas turbine engine cooling system also includes a heat pipe including a first end, a second end, and a conduit extending therebetween. The first end is thermally coupled to the undercowl component, and the second end is thermally coupled to the cold sink. The heat pipe facilitates transfer of a quantity of heat from the undercowl component to the cold sink.

A system for harnessing solar energy using heating applications to generate intense heat for steam boilers and all other water heating applications. Electricity is generated using a steam turbine engine that employs a bank of four biconvex octave lenses, with each having specific sizes, radii, arc convexity and distances from one another in mathematical orderliness in compliance with the Geometry of Space and the Law of Octave of Elements of Matter. The focal points of these lenses are positioned onto a boiler tank consisting of a pair of flat steel sheets in which water runs through from one side and comes out as steam on the other side of it. The steam is then fed into a steam turbine engine to generate electricity. A dual axle sun tracker is adjusted beneath the boiler plate to track the sun's movement from both east to west and north to south at all times. A system of highly conductive carbon rods is assembled on top of the Tasoptic lenses to be activated and subsequently produce an intense arc of hot white light to simulate the sun's parallel rays during the night and cloudy days for the continuity of operation at all times.

The present invention relates to an optical clear resin and a method for producing a liquid optical clear photo-curable adhesive.

There are provided an adhesive for a solar-cell back sheet having an excellent curing rate and being capable of exhibiting excellent adhesive performance by short-term aging, and also a polyol composition used for the adhesive, a solar-cell back sheet using the adhesive, and a solar-cell module using the sheet. The adhesive for a solar-cell back sheet contains, as essential components, at least one hydroxyl group-containing resin (A) selected from a polyester polyurethane polyol (A1), a polyester polyol (A2), a hydroxyl group-containing (meth)acrylic resin (A3), and a hydroxyl group-containing fluorocarbon resin (A4), a polyisocyanate (B), and a cyclic amide compound (C).

There is described a sonotrode for sealing an opening device onto a hole of a packaging material destined to from a sealed package, comprising: a sealing surface adapted to cooperate with a said packaging material in order to seal the opening device to the packaging material; a cavity bounded by an opening of sealing surface and adapted to receive the opening device; and a ring made in an elastomeric material, partially protruding inside the cavity, and adapted to center a first axis of the opening device on a second axis of the sonotrode.

A plasma processor, including a first gas supplier to supply first gas to the inside of a vacuum vessel, a stage on which a wafer is placed, an electromagnetic wave supplier to supply electromagnetic waves for generating first plasma, a susceptor provided to an outer peripheral portion of the stage, a second high frequency power source connected to the susceptor, and a second gas supplier to supply second gas to the inside of the susceptor. The inside of the susceptor is provided with a high frequency electrode connected to the second high frequency power source and a first earth electrode disposed opposite to the high frequency electrode. The second high frequency power source supplies high frequency power while the second gas supplier supplies the second gas, thereby generating second plasma inside the susceptor.

A vapor compression system comprising a centrifugal compressor (22) having: an inlet (24); an outlet (26); a first impeller stage (28); a second impeller stage (30); and a motor (34) coupled to the first impeller stage and second impeller stage. A first heat exchanger (38) is downstream of the outlet along a refrigerant flowpath. An expansion device (56) and a second heat exchanger (64) are upstream of the inlet along the refrigerant flowpath. A bypass flowpath (120; 320) is positioned to deliver refrigerant from the compressor bypassing the first heat exchanger. A valve (128) is positioned to control flow through the bypass flowpath, wherein: the bypass flowpath extends from a first location (140) intermediate the inlet and outlet to a second location (142; 342) downstream of the first heat exchanger along the refrigerant flowpath.

This invention relates to oil lubricated helium compressor units for use in cryogenic refrigeration systems, operating on the Gifford McMahon (GM) or Brayton cycle. The objective of this invention is to provide redundancy by having a water cooled compressor manifolded to an air cooled compressor and sensors to detect faults so that an expander can be kept running if there is a failure in either the water or air supply.

This invention relates generally to oil lubricated helium compressor units for use in cryogenic refrigeration systems, operating on the Gifford McMahon (GM) cycle. This invention provides redundancy between water cooling and air cooling if there is a blockage in the water or air supply by having air and water cooled after-coolers in series or parallel.

Provided is an hybrid solar heat absorption cooling system comprising: an absorption refrigerator; a solar heat steam generator configured to generate steam using solar heat; a daytime steam supplying unit configured to supply steam generated by the solar heat steam generator during the day as a heat source for the absorption refrigerator; a daytime hot water storage tank configured to store hot water discharged from the absorption refrigerator during the day; a nighttime hot water supplying unit configured to supply hot water stored in the daytime hot water storage tank during the night as a heat source for the absorption refrigerator; a nighttime hot water storage tank configured to store hot water discharged from the absorption refrigerator during the night; and a daytime hot water supplying unit configured to supply hot water stored in the nighttime hot water storage tank during the day to the solar heat steam generator.

The present invention provides for a system for calibrating operation of a compressor unit in a heating, ventilation, and air conditioning (HVAC) system. A measuring device measures an operating parameter of the HVAC system at a position where the measuring device is mounted on a refrigerant line of the HVAC system. The measuring device switches states when the value of the measured operating parameter reaches a switching value. A controller estimates a value of the first operating parameter at the position where the first measuring device is mounted on the refrigerant line, and the controller determines whether the estimated first operating parameter is within a threshold percentage of the switching value.

As shocking fact is laid upon shocking fact, it becomes hard to judge SS Mendi- Dancing The Drill Of Death at NST City as a piece of theatre, such is one’s outrage at how the British behaved towards black people from the Empire a hundred years ago. But Isango Ensemble have created a powerful musical to tell the human story behind the appalling facts.

Women In Power at the Nuffield Southampton Theatres’ city venue is a new version of Aristophanes' Assemblywomen. It sticks pretty closely to the original story in which women take over the government from the weak and incompetent men.

Brian Batchelor, once described by the Daily Echo as ‘the most versatile singer in the South’, has died at the age of 87.

News you don't want to miss for April 13:

1. "If the country’s most popular coronavirus model proves accurate, California will reach the peak of its outbreak this Wednesday," the San Francisco Chronicle reports, when it will reach a predicted 66 deaths.…

News you don't want to miss for April 14:

1. Six of the 15 confirmed covid-19 cases at Santa Rita Jail have recovered, the East Bay Times reports.…

News you don't want to miss for April 16:

1. As if you didn't have enough to worry about, but California may be heading toward a historic drought, the type that has only occurred four times in the past 1,200 years, the San Francisco Chronicle reports.…

News you don't want to miss for April 22:

1. Oakland is looking at a potentially historic $80 million budget shortfall over the next year, Bay City News reports.…

News you don't want to miss for April 29:

1. Alameda County and five other Bay Area counties issued a revised shelter in place order on Wednesday that will allow for some outdoor activities to resume, such as, construction work, landscaping, gardening, golf and tennis, SFGate reports.…

News you don't want to miss for May 4:

1. Businesses such as bookstores, florists, clothing retailers, among others, can begin to reopen on Friday, Gov. Gavin Newsom announced, according to the Associated Press.…

News you don't want to miss for May 8-10:

1. Oakland Mayor Libby Schaaf warned she may consider closing some city parks, including Lake Merritt, if social distancing rules are not followed, KTVU reports.…

A preferred embodiment of the present invention contemplates a baseball cap-type hat having a head covering portion as well as a forward facing bill. A sweat or liquid absorbing element preferably a terry cloth towel is removably attached to the bill or permanently affixed using hook and pile fastening means. In a preferred embodiment, the hook and pile fastening means half attached to the bill includes an opening to provide a storage compartment in which a key, coin, or other small object may be stored. If desired, the towel may be permanently stitched to the underside of the bill of the cap. In a further alternative, the towel may be made of a hyper-evaporative material.

The present invention provides color-coded accessories such as wristbands, bibs, and other patient wearables, color-coded pillows and pillow cases, and a universal chart wherein the color code is associated with a specific medical diagnosis. These accessories alert healthcare providers to the medical diagnosis of the patient and enhance patient safety by reducing medical errors during administration of treatments and medicines to the patients. These accessories also provide protection to healthcare providers assisting them to identify diagnostic categories and alerting them to take proper precautions with patients, for example those with infectious diseases, thereby decreasing or preventing transmission of infectious diseases.

The invention relates to an absorbent garment inlay configured for attachment within an underarm portion of a shirt. The inlay includes an inner layer having a wicking material, configured to wick moisture therethrough, and an outer layer having an absorbent material. The outer layer is configured to absorb moisture wicked through the inner layer.

A protective sports accessory for protecting a hand of a user when striking includes a wrist wrap configured for strapping around a wrist of the user. A finger grip is configured for gripping with fingers when the hand is formed into a fist. A tensioning member interconnects the wrist wrap and the finger grip, the wrist wrap, the finger grip and the tensioning member being configured for setting up tension in the tensioning member when the hand is formed into the fist.

Socks, men's and womens, any and every type, with insoles, any and every type, manufactured as one piece allowing users to change shoes taking their insoles with them as “sock/insoles”, rather than buying separate insoles for every pair of shoes.

An article having an inner article layer and an outer article layer to be worn by a mammal comprising a thermally insulating layer of a reflective metalized polymeric insulation material having moisture vapour transference properties adjacent to at least one of the inner and outer article layers. An apparatus and method for producing a reflective metalized polymeric thermally insulating assembly having moisture vapour transference properties suitable for use in the article is also provided. The insulation material provides enhanced thermal retention.

Sole structures (e.g., midsoles and/or outsoles) and articles of footwear include heel-supporting areas and/or forefoot-supporting areas that include a central area (e.g., a central recessed area) and a plurality of surrounding rings. Additionally or alternatively, the sole structures (e.g., midsoles and/or outsoles) may include bands of material defined by recessed grooves to provide a bumpstop type impact-force attenuating structure.

Sole structures include (a) a first midsole component formed at least in part from a first polymeric foam material, wherein the first midsole component forms at least a majority of a plantar support surface and at least a majority of a medial sidewall surface of the sole structure, and wherein the first midsole component includes a lateral side edge; and (b) a second midsole component formed at least in part from a second polymeric foam material, wherein the second midsole component forms at least a majority of a lateral sidewall surface of the sole structure, wherein the second midsole component includes a medial side edge that extends adjacent the lateral side edge of the first midsole component. The second polymeric foam material may have a higher durometer than the first polymeric foam material.

An outsole of a shoe includes: a plurality of ridges having a tread surface to be in contact with a road surface; and at least one longitudinal groove defined between the plurality of ridges. At least in a partial area of each of a forefoot portion and a rear foot portion on a medial side of a foot, the plurality of ridges and the longitudinal groove extend in a longitudinal direction or a diagonal longitudinal direction and are set so that an angle of the ridges and that of the longitudinal groove with respect to a long axis of the outsole are in a range of 0° to 35°. A ratio of a length of the tread surface of the ridges with respect to a width of the tread surface is set to be 1.8 to 200. The width of the tread surface of the ridges is set to be greater than a width of the longitudinal groove by a factor of 2 to 100.

A cushioning sole for footwear includes a heel portion, an opening, and a cushioning slide. The heel portion includes a top surface and a bottom surface. The opening extends vertically through the heel portion from the bottom surface to the top surface. The cushioning slide is disposed in the opening and extends out from the top surface and out from the bottom surface.

A method for providing parts of waterproof and breathable shoes, parts of waterproof and breathable shoes provided with the method, and waterproof and breathable soles provided with the shoe parts. The method uses a mold including a first element and a second element, at least one of which has hollow regions of a matrix of impressions, which are filled with polymeric material in the fluid state by depositing it in the hollow regions or by injecting it while the mold is closed; a support made of flexible sheet is interposed between the first element and the second element and includes a waterproof and breathable functional element, on which, when the mold is closed, the polymeric material sets and adheres to the support.

An article of footwear includes projection members providing sensory feedback. The projection members are movable relative to an upper of the article of footwear. When the upper encounters a surface of an object, the projection members may be displaced in a direction towards wearer's foot. The projection members may be configured so that they are inserted into apertures located on the upper, and extend above an outer surface of the upper.

The present invention relates to a sole element, such as an insole, for a shoe, in particular for a sports shoe, as well as to a shoe, in particular a sports shoe. A sole element for a shoe comprises a first portion and a second portion, wherein the second portion comprises a deformable material, which is adapted to generate heat by being deformed. The sole element moreover comprises a transport element adapted for selectively directing the generated heat from the second portion to the first portion.