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Photoresponsive prodrug-based liposomes for controllable release of the anticancer drug chlorambucil

By pubs.rsc.org
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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01620C, Paper
Xiaoting Wang, Guangtian Suo, Shinan Ma, Chunxi Yang, Chunyan Bao
A photoresponsive lipid prodrug was designed to form nanomedicines for accurate and controllable drug release in response to light irradiation.
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Scalable fabrication of porous membrane incorporating human extracellular matrix-like collagen for guided bone regeneration

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J. Mater. Chem. B, 2024, 12,11142-11155
DOI: 10.1039/D4TB00962B, Paper
Qingyi Wang, Feng Zhou, Tiecheng Qiu, Yiling Liu, Wenxin Luo, Zhanqi Wang, Haiyun Li, E. Xiao, Qiang Wei, Yingying Wu
We fabricated a PCL/hCol membrane with an asymmetric porous structure for guided bone regeneration via nonsolvent-induced phase separation method. It shows superior mechanical and degradation properties, biocompatibility and osteoinductive effect.
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Enzymatic self-assembly of short peptides for cell spheroid formation

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J. Mater. Chem. B, 2024, 12,11210-11217
DOI: 10.1039/D4TB01154F, Paper
Open Access
Jiaqi Guo, Weiyi Tan, Bing Xu
Biphenyl-capped phosphopeptides instruct cell aggregation into spheroids, with minimal effective concentrations below 10 μM. Key factors driving morphogenesis include the self-assembly ability and dynamic shapeshifting of the peptide assemblies.
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Acellular dermal matrix hydrogels promote healing of radiation-induced skin injury in a rat model

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J. Mater. Chem. B, 2024, 12,11218-11229
DOI: 10.1039/D4TB00941J, Paper
Xin Liu, Tian Guo, Zhifeng Huang, Sen Chen, Li Chen, Chenyang Li, Tian Tian, Yerong Qian, Lifei Yang, Junxi Xiang, Qiufang Liu, Peng Liu
Using a novel rat model of RISI, the research demonstrates that ADM hydrogel effectively reduces wound area and severity, increases epithelial thickness, and accelerates healing compared to controls.
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Improving the sulfite-detection performance of a fluorescent probe via post-synthetic modification with a metal–organic framework

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J. Mater. Chem. B, 2024, 12,11251-11258
DOI: 10.1039/D4TB01754D, Paper
Jing-Yi Shi, Bin Wang, Xin-Yue Cui, Xiao-Wei Hu, Hai-Liang Zhu, Yu-Shun Yang
In this work, a post-synthetic modification strategy was attempted to improve the performance of the probe for sulfite detection.
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Drug-delivery and biological activity in colorectal cancer of a supramolecular porous material assembled from heptameric chromium-copper-adenine entities

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Published On ::

J. Mater. Chem. B, 2024, 12,11156-11164
DOI: 10.1039/D4TB01521E, Paper
Sandra Mena-Gutiérrez, Ekain Maiza-Razkin, Jon Pascual-Colino, Marcos J. Araúzo-Bravo, Garikoitz Beobide, Oscar Castillo, Ainara Castellanos-Rubio, Daniela Gerovska, Antonio Luque, Sonia Pérez-Yáñez
Supramolecular metal-organic porous materials as drug delivery systems, modulation of the release kinetics using cholesterol as pore blocking agent and its impact on colorectal cancer cell cultures: cytotoxicity and RNA-seq transcriptomics studies.
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Nordihydroguaiaretic acid microparticles are effective in the treatment of osteoarthritis

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J. Mater. Chem. B, 2024, 12,11172-11186
DOI: 10.1039/D4TB01342E, Paper
Kaamini M. Dhanabalan, Bhagyashree Padhan, Ameya A. Dravid, Smriti Agarwal, Nicholas M. Pancheri, Angela Lin, Nick J. Willet, Ashok Kumar Padmanabhan, Rachit Agarwal
Sustained delivery of NDGA via polymeric microparticles maintains therapeutic levels in joints, reduces cartilage damage, and alleviates post-traumatic osteoarthritis (PTOA) in mice through ROS modulation and autophagy induction.
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Advances in osteoimmunomodulation of biomaterials after intrabone implantation: focus on surface hydrophilicity

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J. Mater. Chem. B, 2024, 12,11089-11104
DOI: 10.1039/D4TB01907E, Review Article
Xinpeng Wei, Linshan Lei, Ling Luo, Ying Zhou, Zheng Zheng, Wenchuan Chen
Hydrophilicity of implantable biomaterials can facilitate osteoimmunomodulation through influencing proteins adsorption, blood clotting, neutrophils activation, macrophages polarization, angiogenesis and osteogenesis to enhance osseointegration.
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Microfluidic synthesis and accurate immobilization of low-density QD-encoded magnetic microbeads for multiplex immunoassay

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11230-11236
DOI: 10.1039/D4TB01585A, Paper
Zhou Sha, Tianyi Ling, Wenqi Yang, Haosu Xie, Chunnan Wang, Shuqing Sun
Accurate immobilization of microbeads in the gap of nickel patterns.
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An innovative electrohydrodynamics-driven SERS platform for molecular stratification and treatment monitoring of lung cancer

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01434K, Highlight
Tuotuo Zhang, Biao Dong, Huiling Wang, Shuai Zhang
A schematic electrohydrodynamics-driven SERS platform to profile four proteins on sEVs to generate a unique molecular signature for lung cancer stratification.
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Effect of supramolecular peptide hydrogel scaffold charge on HepG2 viability and spheroid formation

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01701C, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Yu Xin, Cosimo Ligorio, Marie O’brien, Richard Collins, Siyuan Dong, Aline F. Miller, Alberto Saiani, Julie E. Gough
Understanding how fibre charge in self-assembling peptide hydrogel networks affect HepG2 cell fate and spheroid formation.
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Correction: Blood-clotting model and simulation analysis of polyvinyl alcohol–chitosan composite hemostatic materials

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11265-11266
DOI: 10.1039/D4TB90174F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Yifan Zhao, Junhong Hao, Zexin Chen, Mengmeng Li, Jianxun Ren, Xiaobing Fu
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Controlled therapeutic cholesterol delivery to cells for the proliferation and differentiation of keratinocytes

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11110-11122
DOI: 10.1039/D4TB01015A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Krzysztof Berniak, Ahmadreza Moradi, Agata Lichawska-Cieslar, Weronika Szukala, Jolanta Jura, Urszula Stachewicz
The research concept involves investigating how cholesterol endocytosis impacts cells using electrospun fibers as a carrier. We studied keratinocyte proliferation and evaluated gene expression levels for markers of early and late differentiation.
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Development of enzymatically crosslinked natural deep eutectogels: versatile gels for enhanced drug delivery

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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01672F, Paper
Liane Meneses, Dimitra Antonia Bagaki, Ana Roda, Alexandre Paiva, Ana Rita C. Duarte
We propose a new injectable eutectogel prepared by enzymatic crosslinking, using NADES, betaine : glycerol (2 : 1), as solvent. The potential of using this material with improved rheological properties as drug delivery system, has also been evaluated.
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Navigating predictions at nanoscale: a comprehensive study of regression models in magnetic nanoparticle synthesis

By pubs.rsc.org
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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB02052A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Lukas Glänzer, Lennart Göpfert, Thomas Schmitz-Rode, Ioana Slabu
The transformative power of support vector regression in optimizing magnetic nanoparticle synthesis intricate relationships between process parameters and particle size, enabling the production of particles with tailored properties.
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Machine Learning-Assisted Pattern Recognition and Imaging of Multiplexed Cancer Cells via Porphyrin-Embedded Dendrimer Array

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01861C, Paper
Jiabao Hu, Weiwei Ni, Mengting Han, Yunzhen Zhan, Fei Li, Hui Huang, Jinsong Han
Early cancer detection plays a vital role in improving the survival rate of cancer patients, underscoring the importance of developing cancer detecting methods. However, it is of great challenge to...
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Enhanced Luminescence and Stability of TFMDSA Nanoparticles via Polymer-Induced aggregation for Bioimaging

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Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01825G, Paper
Xiang Li, Xue Ren, Yuchao Luo, Haotian Shi, Zhigang Xie, Bin Xu, Wenjing Tian
In recent years, fluorescence imaging occupies a very important position in the life science and biomedical fields. However, achieving nanomaterials for bioimaging with both high fluorescence quantum efficiency and high...
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Research Progress of Nitroxide Radical-Based MRI Contrast Agents: From Structure Design to Application

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB02272F, Review Article
Tao Luo, Bo Wang, Runxin Chen, Qi Qi, Ruodai Wu, Shunzi Xie, Hanbing Chen, Jialei Han, Dalin Wu, Shuaishuai Cao
Magnetic resonance imaging (MRI) remains a cornerstone of diagnostic imaging, offering unparalleled insights into anatomical structures and pathological conditions. Gadolinium-based contrast agents have long been the standard in MRI enhancement,...
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Nano-Bio Interactions of Gum Arabic-Stabilized Lanthanide-based Upconverting Nanoparticles: In Vitro and In Vivo Study

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01579G, Paper
Hana Mirmajidi, Hyojin Lee, Niepukolie Nipu, Jith Thomas, Zuzana Gajdosechova, David Kennedy, Jan A. Mennigen, Eva Hemmer
Lanthanide-based nanoparticles (Ln-NPs) are highly valued for their unique optical and magnetic properties, making them useful in various scientific fields, including materials science and biomedicine. This study investigated the use...
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Exchange of free and capsule conjugated cyanine dyes between cells

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01874E, Paper
Zhanna V. Kozyreva, Polina A. Demina, Olga I. Gusliakova, Gleb B. Sukhorukov, Olga A. Sindeeva
Cells readily exchange free cyanine dyes when their membranes are in close contact. Photoconvertible capsules based on cyanine dyes are internalized into the cytoplasm with a low degree of exchange, allowing individual cell labeling and tracking.
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Development of a Xanthene-Based NIR Fluorescent Probe for Accurate and Sensitive Detection of γ-Glutamyl Transpeptidase in Cancer Diagnosis and Treatment

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01841A, Paper
Chia-Kai Lai, KUPPAN MAGESH, Sivan Velmathi, Shu-Pao Wu
γ-Glutamyl transpeptidase (GGT) regulates glutathione (GSH), essential for cell functions and linked to cancer. High GGT levels in tumors make it a valuable cancer biomarker. Current GGT detection methods often...
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Quantum DFT analysis and molecular docking investigation of various potential breast cancer drugs

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Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01803F, Paper
Ashraf Ayub, Ankit Raj Tyagi, Sunil Kumar Srivastava, Pranveer Singh
Breast cancer is the most often diagnosed and deadliest type of cancer in the world. These days, the world is facing the threat of breast cancer. It is essential to...
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Functionalities of pH-responsive DNA nanostructures in tumor-targeted strategies

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Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01883D, Review Article
Liyue Wen, Min Wang
Design and application of various pH-responsive DNA nanostructures for tumor-targeted strategies toward extracellular and intracellular environments are comprehensively reviewed. Their potential and challenges are also critically discussed.
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Fluorescence sensing techniques for quality evaluation of traditional Chinese medicines: a review

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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01886A, Review Article
Yanyu Xiao, Hui Wang, Chenxia Gao, Xinyi Ye, Yuting Lai, Meiling Chen, Xiaoliang Ren
We summarized the advantages and advanced applications of fluorescence sensing technology compared with other analytical techniques, as well as the challenges and prospects of current application in the field of TCM quality evaluation.
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Bioinspired programmable coacervate droplets and self-assembled fibers through pH regulation of monomers

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Published On ::

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01550A, Paper
Satyajit Patra, Sushmitha Chandrabhas, Subi J. George
Phase separation or phase transitions pervade the biological domain, where proteins and RNA engage in liquid-liquid phase separation (LLPS), forming liquid-like membraneless organelles. The misregulation or dysfunction of these proteins...
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Dual-functional PCN-242 (Fe2Co) MOF for sensitive bacterial endotoxin detection

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J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01944J, Paper
Sivasankar Kulandaivel, Yung-Kang Lu, Chia-Her Lin, Yi-Chun Yeh
This work introduces a novel bimetallic MOF with superior endotoxin detection and enhanced catalytic activity for broader diagnostic applications.
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Toward a gameic world : new rules of engagement from Japanese video games / Ben Whaley.

By darius.uleth.ca
Published On ::

Ann Arbor, Michigan : University of Michigan Press, 2023.


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Teriya Magar wins Jhalak Dikhhla Jaa; says 'hard work paid off'

By www.rediff.com
Published On :: Mon, 23 Jan 2017 11:53:25 +0530

'Lifting this trophy makes me feel like I have achieved that the dream that I had when I began my Jhalak journey.' Teriya Magar wins Jhalak Dikhhla Jaa 9.


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Your FAVOURITE Koffee with Karan episode? VOTE!

By www.rediff.com
Published On :: Mon, 20 Mar 2017 18:44:19 +0530

Killer Kangana or Teasing Twinkle? Take your pick!


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For the great love of British TV shows

By www.rediff.com
Published On :: Tue, 25 Apr 2017 16:15:42 +0530

Love Sherlock, Dr Who, and Downton Abbey? Vanita Kohli-Khandekar finds out how the UK became one the world's largest creators of television content.


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'I am imperfect and proud of it'

By www.rediff.com
Published On :: Tue, 16 Jan 2018 16:27:06 +0530

'The show has brought one major change in me.''I am going to mend my differences with people.''When we can do this in the Bigg Boss house, why can't we do that outside?'


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Which jodi will be EXCITING on Koffee with Karan 6? VOTE!

By www.rediff.com
Published On :: Fri, 19 Oct 2018 12:43:40 +0530

Varun-Katrina or Saif-Sara?


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'Most of them don't deserve to win'

By www.rediff.com
Published On :: Tue, 22 Nov 2022 14:54:01 +0530

'Be it Nimrit or Tina or Shaleen or Sajid Khan, they are all faking it.'


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Is Shiv The MASTERMIND Of Bigg Boss 16?

By www.rediff.com
Published On :: Tue, 29 Nov 2022 13:26:46 +0530

As soon as Shiv announced Nimrit as the captain, Tina lost her cool and started fighting with both of them.


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The Strange Case Of Abdu Rozik

By www.rediff.com
Published On :: Mon, 19 Dec 2022 13:59:59 +0530

Bigg Boss 16 has turned out to be quite different from its previous seasons.


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'I'm out of Bigg Boss becoz of politics'

By www.rediff.com
Published On :: Mon, 23 Jan 2023 12:50:21 +0530

'The easiest thing to do is character assassinate a woman.'


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'You can't prepare to jump off a building'

By www.rediff.com
Published On :: Tue, 23 May 2023 15:29:01 +0530

'We are getting a show to do stuff like jumping off a helicopter.''Even if you pay, you won't get to do these things.'


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Gufi Paintal Of Mahabharat Fame Dies

By www.rediff.com
Published On :: Mon, 05 Jun 2023 15:24:16 +0530

Gufi Paintal, best known for playing Shakuni mama in the epic television serial Mahabharat, died on Monday at a Mumbai hospital due to age-related issues. He was 79.


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