as Synthesis of Asp-based lactam cyclic peptides using an amide-bonded diaminodiacid to prevent aspartimide formation By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00472H, CommunicationWen-Jie Li, Jun-You Chen, Hui-Xia Zhu, Yi-Ming Li, Yang XuA diaminodiacid (DADA) containing an amide bond can be used in Fmoc solid-phase peptide synthesis (SPPS) of an Asp-based lactam cyclic peptide with no aspartimide formation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as Asymmetric total synthesis of humulane sesquiterpenoids alashanoids B, C, E, and F and 2,9-humuladien-6-ol-8-one By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00393D, PaperRasmita Barik, Samik NandaNaturally occurring sesquiterpenes having humulane frameworks are structurally intriguing and possess significant biological profiles.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as Catalyst- and base-free visible light-enabled radical relay trihalomethylation/functional group-migration/carbonylation with CX3SO2Cl By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00292J, PaperJinkai Hu, Chenglei Yang, Xiaotao Qin, Hui Liu, Tongtong Ma, Ao-tong Shi, Qing-Long Lv, Xingman Liu, Jinhui Yang, Dianjun LiA visible light-enabled photocatalyst-free radical trihalomethylation/cyano (or benzo[d]thiazol-2-yl) 1,4-migration/carbonylation reaction of 2-hydroxy-2-hex-5-enenitrile (or (benzo[d]thiazol-2-yl)-pent-4-enol) with CX3SO2Cl (X = F, Cl) is reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as Asymmetric synthesis of the fully functionalized six-membered A-ring of siphonol A By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,2958-2962DOI: 10.1039/D4OB00104D, CommunicationYing Sun, Shaomin Fu, Bo LiuThe asymmetric synthesis of the fully functionalized six-membered A-ring of siphonol A is presented.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as Not exclusively the activity, but the sweet spot: a dehydrogenase point mutation synergistically boosts activity, substrate tolerance, thermal stability and yield By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,3009-3018DOI: 10.1039/D4OB00211C, PaperYu-Ke Cen, Lin Zhang, Yue Jiang, Xiang-Fu Meng, Yuan Li, Chao Xiang, Ya-Ping Xue, Yu-Guo ZhengA single-point mutation of 7α-HSDH achieved the highest activity and synergistically improved substrate tolerance, thermal stability, cofactor affinity, and conversion rate.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as A phosphamide nucleotide analog: a substrate for polymerase synthesis of DNA By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,2963-2967DOI: 10.1039/D4OB00089G, CommunicationJiong Meng, Qiaqia Guo, Xiaona Zhai, Song Yang, Shuai Wang, Pengcheng Wang, Debin JiA phosphamide nucleotide analog (dNTPγNH2) exhibited higher stability than dNTPs and can be recognized by DNA polymerases in PCR.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as Synthesis of alkynyl sulfides via base-promoted nucleophilic ring-opening of α-bromostyrene sulfonium salt By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,2953-2957DOI: 10.1039/D4OB00203B, CommunicationJunqi Zhou, Ziyu Wang, Hanmiao Xu, Mengke Su, Jian WenAn effective method for synthesizing various alkynyl sulfides has been developed using tetramethylene sulfoxide as a sulfur source through base-promoted nucleophilic ring-opening reactions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as Identification and quantification of local antiaromaticity in polycyclic aromatic hydrocarbons (PAHs) based on the magnetic criterion By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,3035-3044DOI: 10.1039/D4OB00114A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Erich Kleinpeter, Andreas KochThe ring current effect of entirely and partly (anti)aromatic PCHs are calculated and employed to visualize, qualify and quantify existing (anti)aromaticity, especially to decide unequivocally between PAHs and PAAHs.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as Photochromism of phenazine-2,3-diol derivatives through excited state intermolecular proton transfer based on keto–enol tautomerization By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00387J, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Kazuki Ohira, Kumpei Kozuka, Naoki Kaneda, Masahiro Yamamoto, Keiichi Imato, Yousuke OoyamaIt was found that phenazine-2,3-diol derivatives exhibit photochromism through excited state intermolecular proton transfer (ESInterPT) processes based on keto–enol tautomerization.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as 3-Halo-5,6-dihydro-4H-1,2-oxazine N-oxides as synthetic equivalents of unsaturated nitrile oxides in the [3 + 2]-cycloaddition with arynes: synthesis of substituted 3-vinyl-1,2-benzisoxazoles By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00391H, CommunicationAlexander A. Lukoyanov, Svetlana A. Aksenova, Andrey A. Tabolin, Alexey Yu. Sukhorukov3-Halo-1,2-oxazine N-oxide derivatives act as surrogates of vinyl nitrile oxides in tandem [3 + 2]-cycloaddition/[3 + 2]-cyclofragmentation with arynes leading to benzisoxazoles.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as Electro-oxidative three-component cascade coupling of isocyanides with elemental sulfur and amines for the synthesis of 2-aminobenzothiazoles By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00432A, PaperPeng-Fei Huang, Jia-Le Fu, Ying Peng, Jian-Hong Fan, Long-Jin Zhong, Kewen Tang, Yu Liu2-Aminobenzothiazoles are commonly encountered in various functional compounds. Herein, we disclose an electro-oxidative three-component reaction for the effective synthesis of 2-aminobenzothiazoles under mild conditions, utilizing non-toxic and abundant elemental sulfur...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as Design, synthesis, biological evaluation and molecular docking studies of quinoline-anthranilic acid hybrids as potent anti-inflammatory drugs By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00040D, PaperSidra Siddique, Khalid Hussain, Naureen Shehzadi, Muhammad Arshad, Muhammad Nadeem Arshad, Sadaf Iftikhar, Farhat Saghir, Ayisha Shaukat, Muhammad Sarfraz, Nisar AhmedDespite the high global prevalence, rheumatoid arthritis lacks a satisfactory treatment.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as An FeCl3-catalyzed three-component reaction for the synthesis of β-(1,2,3-triazolyl)-ketones using DMF as a one-carbon source By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00207E, CommunicationRuilin Fang, Lei Zheng, Xuyang Chen, Can Wang, Yunfeng ChenFeCl3-catalyzed oxidative condensation of NH-1,2,3-triazoles and aryl methyl ketones and DMF has been reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as Measuring local pH at interfaces from molecular tumbling: A concept for designing EPR-active pH-sensitive labels and probes By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00167B, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Maxim A. Voinov, Nicholas Nunn, Roshan Rana, Atli Davidsson, Alex I. Smirnov, Tatyana I. SmirnovaEPR-based local pH measurements based on changes in rotational dynamics of spin-bearing molecules upon protonation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as A Highly Diastereoselective One-Pot Ugi/Radical Spirocyclization/Aza-Michael Addition Sequence By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00610K, CommunicationChandra Volla, Salman Khan, Abhradeep Chatterjee, Akshay Murali NairWe hereby report a highly diastereoselective synthesis of chalcogenated azaspirotricycles via a one-pot Ugi/spirocyclization/ aza-Michael addition sequence. The reaction proceeded via a key visible light mediated spirocyclization step under mild,...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as Regioselective synthesis of 4-arylamino-1,2-naphthoquinones in eutectogel as a confined reaction medium using LED light By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00140K, CommunicationR. Vara Prasad, Yogendra Kumar, R. Arun Kumar, Tohira Banoo, Subbiah NagarajanThe use of a simple carbohydrate-derived eutectogel facilitating a LED-light-induced regioselective synthesis of 4-arylamino-1,2-naphthoquinones in good yields is reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as Efficient synthesis of SCF3-containing 3-alkenylquinoxalinones via three-component radical cascade reaction By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00363B, PaperSi-Yu Wang, Chu Liu, Wei Yang, Zhong-Ying Tian, Lin Yuan, Long-Yong XieA three-component cascade reaction of quinoxalinones, alkynes and AgSCF3 toward complete E-selective SCF3-containing 3-alkenylquinoxalinones was developed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as Base- and sulfur-promoted oxidative lactonization of chalcone-acetate Michael adducts: access to pyran-2-ones By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00479E, CommunicationCao Nguyen Nguyen, Duc Toan Nguyen, Ha An Tran, Dinh Hung Mac, Thi Thu Tram Nguyen, Pascal Retailleau, Thanh Binh NguyenA cost-effective, practical, straightforward and scalable synthesis of α-pyrones via base- and sulfur-promoted annulation of phenylacetates and chalcones is reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
as How long do commercial aircraft last? By www.thehindubusinessline.com Published On :: Sun, 13 Jun 2021 18:58:46 +0530 What airlines can do to extend the longevity of their fleet Full Article Flight Plan
as As the price of aviation turbine fuel soars, airlines’ finances spin out of control By www.thehindubusinessline.com Published On :: Sun, 25 Jul 2021 16:35:44 +0530 Full Article Flight Plan
as ‘The challenge was in getting the aircraft’s custom clearance’ By www.thehindubusinessline.com Published On :: Sun, 22 Aug 2021 15:46:05 +0530 Private jet operator JetSetGo’s CEO Kanika Tekriwal describes the intricacies of directly importing and leasing an aircraft Full Article Flight Plan
as Gearing up to fly twice as fast as sound By www.thehindubusinessline.com Published On :: Sun, 05 Sep 2021 17:14:22 +0530 The US-based start-up Boom Supersonic is putting together an aircraft that can fly at a maximum speed of Mach 2.2 Full Article Flight Plan
as IFSC: Aircraft leasing gets a big boost By www.thehindubusinessline.com Published On :: Sun, 14 Nov 2021 20:01:57 +0530 Around 80 per cent of the total commercial fleet in India is leased against 53 per cent of the same, globally Full Article Logistics
as A380: How Airbus forecast misfired By www.thehindubusinessline.com Published On :: Sun, 26 Dec 2021 18:20:55 +0530 Sinks $25 billion in the process Full Article Flight Plan
as As India builds its newest airports, it needs robust, fail-proof SOPs By www.thehindubusinessline.com Published On :: Mon, 24 Jan 2022 10:23:59 +0530 A near air mishap on Bengaluru skies that put the lives of 430 people in danger shows safety risk norms require constant refresh Full Article Flight Plan
as In case the engine gives out By www.thehindubusinessline.com Published On :: Sun, 03 Apr 2022 18:42:49 +0530 If an aircraft’s engine fails, the pilot has nearly half an hour to find a landing spot Full Article Flight Plan
as Will Akasa Air’s contra bet on Boeing 737 Max instead of Airbus pay off? By www.thehindubusinessline.com Published On :: Sun, 07 Aug 2022 20:00:00 +0530 Rakesh Jhunjhunwala’s Akasa airline has gone against the tide, placing its bets on Boeing aircrafts; it now needs to carve out a niche for itself Full Article Flight Plan
as Air infrastructure plans should be future-proof By www.thehindubusinessline.com Published On :: Sun, 04 Sep 2022 22:00:00 +0530 India’s aviation story is full of delayed, untapped and under-utilised potential Full Article Flight Plan
as Why do plane crashes happen? By www.thehindubusinessline.com Published On :: Sun, 18 Sep 2022 21:00:00 +0530 Full Article Flight Plan
as Post-pandemic, OTAs are coming of age By www.thehindubusinessline.com Published On :: Sun, 18 Sep 2022 21:00:00 +0530 Are they finally paying up or paying off? Full Article Flight Plan
as Why has private capital not been taken to Indian aviation By www.thehindubusinessline.com Published On :: Sun, 30 Oct 2022 21:00:00 +0530 With banks becoming increasingly cautious and credit flows tightening, private capital must be explored and enticed Full Article Flight Plan
as Google’s moneymaking machine still pumping out massive profits despite multiple threats By www.thehindu.com Published On :: Wed, 30 Oct 2024 08:18:51 +0530 Google is still thriving while the company navigates through a pivotal shift to artificial intelligence and battles regulators trying to topple its internet empire Full Article Technology
as As Bitcoin nears all-time high, WazirX investors are in pain over their locked crypto funds By www.thehindu.com Published On :: Wed, 30 Oct 2024 13:27:39 +0530 Bitcoin was inching towards its March 2024 all-time-high price of $73,750.07, but those whose crypto assets are locked with the WazirX exchange after a cyberattack are anxious about missing out Full Article Technology
as ChatGPT will now work as a search engine as OpenAI partners with some news outlets By www.thehindu.com Published On :: Fri, 01 Nov 2024 08:24:52 +0530 OpenAI is launching a ChatGPT-powered search engine that could put the artificial intelligence company in direct competition with search giant Google Full Article Technology
as Amazon won’t release new Alexa until 2025: Report By www.thehindu.com Published On :: Fri, 01 Nov 2024 11:59:02 +0530 Until sometime ago, users were able to access the beta version of Alexa using an Echo but that has been cut off now Full Article Technology
as Transformation Stories #4 A New Podcast Interview With Me (Rob Larsen) By htmlcssjavascript.com Published On :: Wed, 28 Feb 2024 18:33:05 +0000 Check out yours truly on an episode of Atlas Systems’ Transformation Stories. A hands-on leader and change-maker with 20 years of experience, Rob Larsen remains at the forefront of software-led innovation – in financial services and the larger enterprise world. In this all-new conversation with Atlas Systems, Larsen offers insights into finding the right pace […] Full Article CSS HTML Web
as HTML5 Boilerplate 9.0.1 Released By htmlcssjavascript.com Published On :: Tue, 16 Apr 2024 16:49:28 +0000 See it on GitHub! View it on npm! This release was kicked off because of Gulp 5. Gulp 5 has breaking changes so we had to work through the upgrade manually. In the process of doing that upgrade we discovered a couple of bugs. Christian Oliff noticed that tests were failing on Windows I noticed […] Full Article CSS HTML Web h5bp
as Out-of-pocket expenditure on health in Kerala is highest in country despite increased State investments By www.thehindu.com Published On :: Sun, 20 Oct 2024 18:13:50 +0530 National Health Accounts figures show the per capita out-of-pocket expenditure on health in Kerala stands at ₹7,889. However, Kerala also tops the list when it comes to the per capita government spending on health, at ₹4,338 Full Article Health
as Dietary restriction or good genes: new study tries to unpack which has greater impact on lifespan By www.thehindu.com Published On :: Mon, 21 Oct 2024 16:50:20 +0530 If we know that genetics and lifestyle affect how long you live, which one is more important? And how do they interact? Full Article Health
as WHO certifies Egypt as malaria-free; calls it ‘historic feat’ ending ancient scourge By www.thehindu.com Published On :: Tue, 22 Oct 2024 10:48:04 +0530 Globally, 44 countries and one territory have now been certified as malaria-free Full Article Health
as Sexual harassment rampant in Maharashtra medical colleges, finds survey By www.thehindu.com Published On :: Tue, 22 Oct 2024 15:31:00 +0530 The survey also found that a majority of students believed that reporting these events could negatively affect their grades and future prospects; it highlighted the need for better safety mechanisms on campus Full Article Health
as Rapid assessment of pulse polio campaign shows high vaccine coverage, highlights gaps in Chennai By www.thehindu.com Published On :: Tue, 22 Oct 2024 15:41:02 +0530 Chennai accounted for nearly 21% of the non-vaccinated children, highlighting the gaps in an urban area and the need for targeted community outreach Full Article Chennai
as Acute Flaccid Paralysis surveillance as a crucial defence against polio in India | Explained By www.thehindu.com Published On :: Wed, 23 Oct 2024 14:26:23 +0530 India needs to continue efforts to maintain its polio-free status, and AFP surveillance has to remain a cornerstone of its strategy Full Article Health
as Rajasthan-based firm barred from making ‘Insulin’ homeopathic tablets By www.thehindu.com Published On :: Thu, 24 Oct 2024 18:22:48 +0530 A licence for the manufacture of this product was cancelled; this follows a complaint from Kerala-based RTI activist K.V. Babu with the Prime Minister’s public grievance cell Full Article Health
as Trachoma eliminated as a public health problem in India; what next? By www.thehindu.com Published On :: Fri, 25 Oct 2024 06:00:00 +0530 The achievement marks a significant public health victory and has profound economic implications. Trachoma’s impact, through blindness and visual impairment, results in an estimated economic loss of $2.9 to 5.3 billion annually due to reduced productivity Full Article Health
as Drugs regulator finds 49 samples not of standard quality, manufacturers asked to withdraw their products By www.thehindu.com Published On :: Sat, 26 Oct 2024 03:00:00 +0530 Four spurious drugs were also found and action has been initiated against the makers, the DCGI said Full Article Health
as $25-million Pandemic Fund aims to curb ‘zoonotic’ diseases By www.thehindu.com Published On :: Sat, 26 Oct 2024 22:55:35 +0530 The Centre will implement the G20 Pandemic Fund, which is aimed at enhancing the country’s “animal health security”, in partnership with the Asian Development Bank (ADB), the World Bank and the Food and Agriculture Organization (FAO). Full Article Health
as Tuberculosis infected 8 million people last year, the most WHO has ever tracked By www.thehindu.com Published On :: Wed, 30 Oct 2024 14:10:41 +0530 The World Health Organization says more than 8 million people were diagnosed with tuberculosis last year Full Article Health
as As breast cancer incidence rises, doctors raise importance of early detection, need for women to be breast aware By www.thehindu.com Published On :: Wed, 30 Oct 2024 15:49:26 +0530 Chennai accounts for highest crude incidence rate of breast cancer in T.N., data shows; a number of factors have led to this, say doctors Full Article Health
as What is breast density and how is it associated with cancer? Explained By www.thehindu.com Published On :: Sat, 02 Nov 2024 11:10:44 +0530 Breast density matters because of two main reasons: it may make it harder to detect signs of cancer on a mammogram, and it is linked with an increased risk of breast cancer Full Article Health