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OECD Good Laboratory Practice: Frequently asked questions (FAQ)

GLP issues raised by testing labs are covered in this comprehensive list of questions and answers, recently updated with questions related to: sponsors, Contract Research Organisations (CROs), sub-contractors, archives, Information Technology (IT), Biotechnology/GMOs and other miscellaneous issues




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Council Act: Revision to the "Decision-Recommendation on the Co-operative Investigation and Risk Reduction of Chemicals"

The Decision-Recommendation on the Co-operative Investigation and Risk Reduction of Chemicals revises and replaces a 1991 Decision-Recommendation of the Council. The Decision-Recommendation is composed of two parts: Part A focuses on the development of harmonised hazard and exposure assessment methodologies for chemicals and Part B focuses on risk prevention and reduction.




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Guidance on Change of Ownership in Hazardous Facilities

The OECD releases a Guidance on Change of Ownership in Hazardous Facilities. This Guidance is a concise document providing a framework to assist stakeholders to identify, understand and minimise the risks during and after a change of ownership at a hazardous facility, and help make the change of ownership a better informed process.




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Guidance Document on Good In Vitro Method Practices (GIVIMP)

GIVIMP aims to reduce the uncertainties in cell and tissue-based in vitro method derived predictions by applying good scientific, technical and quality practices from method development to implementation for regulatory use. Test method developers and test guideline users will find best practices for designing guideline in vitro methods, carrying out safety tests and assuring quality and scientific integrity of the resulting data




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Webinar: Best Environmental Practices (BEP) for textiles in the context of management of per- and polyfluoroalkyl Substances (PFASs)

Join us for our per- and polyfluoroalkyl substances webinar on Best Environmental Practices (BEP) for Textiles




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Publications in the Series on the Safety of Manufactured Nanomaterials

Nanomaterials have unique physical and chemical features. OECD's Decision Framework and Guiding Principles tools fill data gaps in the hazard characterisation by identifying the most useful parameters and best available methods for a given type of nanomaterial.




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OECD Series on Principles of Good Laboratory Practice (GLP) and Compliance Monitoring

The purpose of this document is to give guidance to Receiving Authorities on the evaluation of the GLP compliance status of nonclinical safety studies submitted for regulatory purposes. This guidance does not address the scientific evaluation and interpretation of the submitted data or the risk assessment based on these data.




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Integrated Approaches to Testing and Assessment (IATA)

Two new cases have been published that focus on use of metabolism information to support read-across and use of a combination of novel methods to identify potential endocrine disruptors, respectively. In addition a considerations document includes lessons and learnings from analysis across case studies and an analysis of uncertainties in six read-across cases.




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The Slow Lane: Class acts

Mussorgsky and Toulouse-Lautrec reached out to people treated as extras rather than full human subjects




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The Slow Lane: Have you got your shame face on?

Feelings of shame, unlike other emotions, are difficult to hide




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Horace – the best self-help there is

It is that forging and tempering that makes the poet’s utterances strong and flexible




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The limitations of democracy

Elected rulers use heavy-handed authority to prevent being toppled by swings in opinion




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Democrats risk over-reach after midterms

Americans resent inquisitions aimed at depriving them of their elected president




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Maersk CEO Soren Skou on surviving a cyber attack

After a stormy summer, the chief is shaking up the world’s biggest shipping company




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The Fast Lane: how to embrace a stint in the slow lane

Returning to 500 emails that need attention is far worse then checking in every other day




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Top Tips for trading contracts for difference

Ten ways to improve your chances when placing a bet




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Forensic auditor to review every transaction at Lebanon’s central bank

Economy minister says comprehensive inspection is part of measures needed to save economy




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Researchers prepare for human challenge trials of Covid-19 vaccine

Deliberately infecting volunteers could accelerate research but raises ethical questions




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Elon Musk sues to reopen Tesla factory in California

Electric carmaker chief threatens to relocate to another state after request to restart production was denied




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Sweden unlikely to feel economic benefit of no-lockdown approach

Analysts forecast that growth will contract at similar rate to rest of Europe




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Macro blogroll for the morning meeting









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This Week in Apps: WWDC goes online, Android 11 delays, Facebook SDK turns into app kill switch

We continue to look at how the coronavirus outbreak is impacting mobile apps; that big app crash caused by Facebook; new app releases from Facebook and Google; and Apple's plans to move WWDC online.




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Tesla sues Alameda County to force California factory reopening

Tesla filed a lawsuit Saturday against Alameda County in an effort to invalidate orders that have prevented the automaker from reopening its factory in Fremont, California. The lawsuit, which seeks injunctive and declaratory relief against Alameda County, was first reported by CNBC. The lawsuit was filed in U.S. District Court for California’s Northern District. Earlier […]




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This Week in Apps: WWDC goes online, Android 11 delays, Facebook SDK turns into app kill switch

We continue to look at how the coronavirus outbreak is impacting mobile apps; that big app crash caused by Facebook; new app releases from Facebook and Google; and Apple's plans to move WWDC online.




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Transgender inmates have carried out seven sex attacks on women in jail

Official figures show for the first time the true scale of offending by criminals who were born male but were allowed to move into female jails after changing gender. Convicted rapist Karen White pictured.




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The doctor who almost died of a heart attack to avoid burdening the NHS

Consultant anaesthetist Dr Paul Trafford, pictured with his wife and nieces, almost suffered a major heart attack after returning to his home in Glasgow following a shift in his hospital due to an undiagnosed issue.




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LORD PATTEN: China's nasty, lying, bullying Communist regime must face judgment over coronavirus

Pin the blame where it belongs. This is not the fault of the Chinese people. It is the Chinese Communist dictatorship which hold the responsibility for the spread of the coronavirus.




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How a joyous snap of VE Day in the Mail on Sunday brought one man's memories flooding back

Tony Cooke's eyes were drawn to a photograph of a group of women in pinafores hailing the end of war, conveying the relief, pride and exultant joy of VE Day.




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Kremlin-linked cyber hackers steal hundreds of medical trial records from British coronavirus lab 

This newspaper revealed last week how hackers linked to Russia and Iran were behind 'utterly reprehensible' hits on British institutions.




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Will Covid-19 survivors face a lifetime of illness like those who battled polio?

Kirstin Coutney, pictured with her daughter Tilly, contracted Covid-19.  The 49-year-old mother of two from Bath is still suffering crippling fatigue, six weeks after developing the virus.




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Matt Hancock's Covid crisis 'trace agents' will have NO medical knowledge

Thousands of vital coronavirus 'contact tracers' are only now being recruited by the Government - two weeks after the Health Secretary first announced they would be hired.




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Photo shows moment shark breaches water at a popular Australian surfing spot 

Dylan Nacass, 23, managed to escape with minor lacerations after a shark latched onto his leg while surfing at Bell's Beach in Torquay, Victoria on Friday afternoon.




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Royal Albert Hall is facing closure as bosses say only a THIRD of seats could be used

Chief executive Craig Hassal said the 2m social distancing rules would force the London venue to cut its capacity to just 30 per cent and close its bars and restaurants, adding the situation is 'desperate'.




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More than half a million Zoom accounts are offered for sale

Crooks can buy usernames, passwords and other data to break into private online meetings and steal sensitive information from banks, financial firms and even universities.




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Marie Stopes abortion charity accepted millions of pounds in funding from US porn baron

Marie Stopes International (MSI) has received more than £7.5million from sex-toy salesman Phil Harvey, critics have now accused the charity of betraying its stated aims.




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Growing popularity of dachshunds may put the breed at risk

Respected breeders will perform DNA screening but potential owners could be duped into buying unhealthy pets from unscrupulous puppy farms abroad.




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Boris Johnson is accused of ignoring terrorist threats

The group of senior Ministers and security officials was due to meet on Thursday but did not, meaning a full NSC meeting has not been convened since February.




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Corbynistas accuse Sir Keir Starmer of plotting a 'betrayal' of his vow to abolish tuition fees

Jeremy Corbyn's backers claim the new Labour Party leader wants to review his predecessor's £7.2 billion pledge, despite promising to honour it during the recent leadership contest.




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President Trump drinks bleach, gives commencement speech to 'the class of COVID-19' in SNL cold open

Alec Baldwin reprised his imitation of President Trump on the season finale of Saturday Night Live - this time with the Commander in Chief giving a commencement speech via Zoom.




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Surfer killed in shark attack in Northern California

A surfer has been killed in a shark attack off a Northern California beach, state park officials said Saturday.




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Coles shopper shares his simple trick to folding shopping bags that will save you space 

A clever Australian shopper has demonstrated how to neatly fold reusable shopping bags to save pantry or drawer space in the kitchen. The bag is folded in certain ways to avoid unravelling.




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Britain's biggest unions threaten to tell workers to refuse return unless workplaces are made safe

Leaders of unions such as Unite, Unison and the General have written an open letter to Boris Johnson demanding the government puts policies in place to make workplaces safe.




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Qantas reveals its top hacks for beating jetlag

Qantas and University of Sydney fatigue specialists from the Charles Perkins Centre have released their findings into how passengers cope with long, overseas flights.




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Qantas orders immediate inspections after CRACKS were found in one of its aircrafts

The cracks were discovered on the 'pickle fork' of a Boeing 737 - the part attaches the body to the wing. Australian airline Qantas vowed to check 33 planes.




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Qantas urged to ground ALL of its 737s after a crack was found in another of the airline's planes 

The Australian airline began immediate checks on 33 planes after a crack was found during routine maintenance checks on Wednesday.