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Brightfield multiplex immunohistochemistry with multispectral imaging




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Molecular signatures of tumor progression in myxoid liposarcoma identified by <i>N</i>-glycan mass spectrometry imaging




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Igniting autophagy through the regulation of phase separation




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Cadmium isotope fractionation reveals genetic variation in Cd uptake and translocation by <i>Theobroma cacao</i> and role of natural resistance-associated macrophage protein 5 and heavy metal ATPase-family transporters




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Correction to: A universal pipeline for mobile mRNA detection and insights into heterografting advantages under chilling stress




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A pentaploid-based linkage map of the ancestral octoploid strawberry <i>Fragaria virginiana</i> reveals instances of sporadic hyper-recombination




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19p loss is significantly enriched in older age neuroblastoma patients and correlates with poor prognosis




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Phase imaging with an untrained neural network




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Adaptive optics two-photon microscopy enables near-diffraction-limited and functional retinal imaging in vivo




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Do extremely preterm infants need retinopathy of prematurity screening earlier than 31 weeks postmenstrual age?




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Gene conversion following CRISPR/Cas9 DNA cleavage: an overlooked effect




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CD24Fc protects against viral pneumonia in simian immunodeficiency virus-infected Chinese rhesus monkeys




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Macrophage subsets at the maternal-fetal interface




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Albumin fusion with granulocyte-macrophage colony-stimulating factor acts as an immunotherapy against chronic tuberculosis




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The genetics of macrophage activation syndrome




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Shortening jet-lag recovery




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Gasdermin D inhibitor protects against sepsis




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50, 100 & 150 Years Ago

Innovation and discovery as chronicled in Scientific American




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Mapping the twist-angle disorder and Landau levels in magic-angle graphene




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Millennial-scale hydroclimate control of tropical soil carbon storage




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Worm brain, ocean giant and soothing Jupiter — April’s best science images




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Smart-technology spies, a final warning on the environment, and the staggering costs of cancer: Books in brief




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Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide




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Blood pressure control and complex health conditions in older adults: impact of recent hypertension management guidelines




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Urate-lowering therapy exerts protective effects against hypertension development in patients with gout




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Management of hypertension in the very old: aggressive reduction of blood pressure is harmful in most patients




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No benefit of initial invasive strategy for managing CAD in advanced CKD




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Disease-associated astrocytes in Alzheimer’s disease and aging




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Single cell and tissue-transcriptomic analysis of murine bladders reveals age- and TNFα-dependent but microbiota-independent tertiary lymphoid tissue formation




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Prize-Winning Images of the Brain

Check out this year's winners of the Art of Neuroscience competition




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Nine-factor-based immunohistochemistry classifier predicts recurrence for early-stage hepatocellular carcinoma after curative resection




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Does multiparametric imaging with <sup>18</sup>F-FDG-PET/MRI capture spatial variation in immunohistochemical cancer biomarkers in head and neck squamous cell carcinoma?




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Telomere-based risk models for the early diagnosis of clinically significant prostate cancer




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MHD surrogate model for convection in electromagnetically levitated molten metal droplets processed using the ISS-EML facility

npj Microgravity, Published online: 16 March 2020; doi:10.1038/s41526-020-0099-7

MHD surrogate model for convection in electromagnetically levitated molten metal droplets processed using the ISS-EML facility




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Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy




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Repository of proposed pathways and protein–protein interaction networks in age-related macular degeneration




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Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging




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The aging human body shape




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npj Aging and Mechanisms of Disease




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The HMGB1-RAGE axis modulates the growth of autophagy-deficient hepatic tumors




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Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE)

Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE.