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Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape




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Asymmetry across the membrane




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TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome




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Nature Chemical Biology




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Rad53 limits CMG helicase uncoupling from DNA synthesis at replication forks




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Author Correction: A structural model for microtubule minus-end recognition and protection by CAMSAP proteins




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Nucleation seed size determines amyloid clearance and establishes a barrier to prion appearance in yeast




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Structure of a proton-dependent lipid transporter involved in lipoteichoic acids biosynthesis




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CDK11 is required for transcription of replication-dependent histone genes




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Real-time observation of CRISPR spacer acquisition by Cas1–Cas2 integrase




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Publisher Correction: High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble




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Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur




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Nature Structural & Molecular Biology




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The drivers of sustained use of liquified petroleum gas in India




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Electrolytes for microsized silicon




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Coal-fired power plant closures and retrofits reduce asthma morbidity in the local population




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COVID-19 assistance needs to target energy insecurity




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Cyanobacterial in vivo solar hydrogen production using a photosystem I–hydrogenase (PsaD-HoxYH) fusion complex




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Nature Energy




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Realizing the gains and losses in <i>C9ORF72</i> ALS/FTD




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Primate auditory prototype in the evolution of the arcuate fasciculus




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Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons




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Within-group synchronization in the prefrontal cortex associates with intergroup conflict




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Disease-associated astrocytes in Alzheimer’s disease and aging




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Hippocampal firing rates count




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Dynamic regulation of Z-DNA in the mouse prefrontal cortex by the RNA-editing enzyme Adar1 is required for fear extinction




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Nature Neuroscience




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Thank you to all 2019 Mucosal Immunology Reviewers




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Seasonal and pandemic influenza: 100 years of progress, still much to learn




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The functions of IL-23 and IL-2 on driving autoimmune effector T-helper 17 cells into the memory pool in dry eye disease




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Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals




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Targeting cellular fatty acid synthesis limits T helper and innate lymphoid cell function during intestinal inflammation and infection




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IL-33/ST2/IL-9/IL-9R signaling disrupts ocular surface barrier in allergic inflammation




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100 years of influenza research seen through the lens of Covid-19




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Single cell and tissue-transcriptomic analysis of murine bladders reveals age- and TNFα-dependent but microbiota-independent tertiary lymphoid tissue formation




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Structure of severe fever with thrombocytopenia syndrome virus L protein elucidates the mechanisms of viral transcription initiation




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The new scope of virus taxonomy: partitioning the virosphere into 15 hierarchical ranks




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Monkeypox virus emergence in wild chimpanzees reveals distinct clinical outcomes and viral diversity




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The Syntrophy hypothesis for the origin of eukaryotes revisited




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Author Correction: Metabolic activity analyses demonstrate that Lokiarchaeon exhibits homoacetogenesis in sulfidic marine sediments




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The continued threat of emerging flaviviruses




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Fetal inheritance of chromosomally integrated human herpesvirus 6 predisposes the mother to pre-eclampsia




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Diversity, ecology and evolution of Archaea




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Nature Microbiology




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The Dark Core of Personality

Nine factors can determine how malevolent you are




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Need More Self-Control? Try a Simple Ritual

Study finds an unusual technique for eating less




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How Can We Tell If a Comatose Patient Is Conscious?

Neurologist Steven Laureys looks for signs of consciousness in unresponsive patients




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Prize-Winning Images of the Brain

Check out this year's winners of the Art of Neuroscience competition




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Unknown Unknowns: The Problem of Hypocognition

We wander about the unknown terrains of life, complacent about what we know and oblivious to what we miss




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A Buddhism Critic Goes on a Silent Buddhist Retreat

Something weird happens to a skeptical science writer during a week of meditation, chanting and skygazing