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Synthesis and antifungal evaluation of new azole derivatives containing 1,2,3-triazole

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00724G, Research Article
Zhengxiao Huang, Hongjie Chen, Xiao Zhang, Ruirui Wang, Chunyan Hu, Zewei Mao
A series of novel azole derivatives containing 1,2,3-triazole have been synthesized with good antifungal effects on sensitive and drug-resistant C. albicans.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




3

Duo arrested for possession of banned tobacco products worth ₹3 lakh in Tiruchi




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Paddy crop loss compensation pegged at ₹36,500




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TNSTC Kumbakonam Division mops up ₹17.13 crore in four days




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543: Zach Leatherman on Eleventy, Mastodon, Twitter, and is-land

Zach Leatherman talks with us about what's new with Eleventy, setting up on Mastodon, what's happened with Twitter, and is-land.




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552: Do You Want to Build a JS Framework? ☃️ CSS Wishlist for 2023

Austin power updates, what do you need if you want to build a new JavaScript framework, and what do we hope CSS brings in 2023?




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553: TypeScript, DX, GripeScript, and Astro v2 with Fred Schott

Fred Schott stops by to talk about TypeScript, what DX means in 2023, a bit of GripeScript, and being transparent about what Astro is good at, and what it's not.




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563: Getting Pulled by the Algorithm, AI Training Data, and SVG Drawing

There's a special guest on the show who takes aim at the billionaires in web dev, do we know better than the algorithm for news, why is AI training data such a secret, Chris and Dave discover JetBrains, monorepo struggles, and SVG drawing tools.




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573: Google Reader, Sticky and Overflow, and Figma Thoughts

Chris breaks out his banjo, some thoughts on making music vs recording music, what happened to Google Reader and social reading, what black box properties can't Dave or Chris remember, follow up for dev teams communicating with designers, and what's Adobe going to do about Figma?




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578: Customer Support, P3 Color, Dave on Productivity, and Mobile vs Desktop

Is Apple's Numbers amazing or the worst? Customer support at various levels of software, Figma and P3 color, imagining a colorspace property in CSS, what's Dave doing for productivity, how has offloading CSS Tricks affected Chris, and should we build different websites for mobile vs desktop?




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580: Chen Hui Jing and the State of CSS Survey for 2023

We're talking the State of CSS Survey, 2023 Edition, with Chen Hui Jing. What was it like helping develop the survey? A bit of follow up on regions, the benefits of being able to tell the browser what you want, language issues in developing and understanding CSS, the struggle for non-majority users, CSS frameworks, and more.




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583: Language Models, AI, and Digital Gardens with Maggie Appleton

Maggie Appleton talks with us about her work at Elicit, working with large and small language models, how humans vet the responses from AI, the discussion around the Soggoth meme in AI, using Discord as UI, what to do if your boss wants AI in your app, and why does she call her blog a digital garden?




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593: Beep & Texts, Tumblr, JavaScript & Web Components, & Cool Blog Post Ideas

Thoughts on smashing all communication messaging apps together, what's happened to Tumblr under Automattic, what the situation is with native web components and JavaScript, and looking at a list of types of blog posts.




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603: Deno, React Alternatives, and Copilot Concerns with Triple Threat Josh Collinsworth

Josh (or Jsoh) stops by to talk about his work at Deno, recent blog posts on Copilot, why Svelte is awesome and React is not, Apple and PWA, and building word games on the web.




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613: Recording Live Music, WebC, Open Source, & WordPress Studio

Chris bought recording gear off an Instagram ad, our thoughts on WebC, CodePen upgrades Yarn, thoughts on the commercial value of open source, Automattic releases an app to install WordPress locally, IBM buys Hashicorp, income tax software, and a hack for getting Safari to respect background colors used in a pseudo selector.




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614: CSS Grid Level 3 aka Masonry with Adam Argyle

Adam Argyle stops by to chat about the conversation that's happening around CSS Grid / Masonry. What do we want? What might Apple's response to Google be? And nitpicking the spec just for fun.




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623: Assigning Weight Dynamically, CoPilot vs Other AI, and Monorepos

We're talking about assigning a weight to items in a layout, differentiating between banger posts and regular blog posts, using social engineering to get PR's accepted, monorepo thoughts, using CoPilot vs other AI programming support bots, has TypeScript benefited from AI, and what happens if you turn off CoPilot?




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630: Frostapalooza Recap, Follow Up, and Messy Codebases

Chris has a birthday today 🎉, we recap our Frostapalooza experience celebrating Brad Frost's birthday, do all codebases become a mess, Mermaid, TLDraw, and Figjam thoughts, making tiny games, where's the follow up in web and world news, and what's the current state of CMS' on the web?




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631: Dave’s Second Brain Idea, Notion Thoughts, and Google’s LLM in Chrome

Dave's got an idea for a second brain app that's customized to his brain, where we're at with Notion and other notes apps, and accessibility on LLM's in browsers.




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632: Adam Coster on Game Development and Crashlands 2

Adam Coster talks with us about working with his family in game development, how they get started making games, what all is involved with publishing games, deciding to go Steam and Netflix only for Crashlands 2, how web tech is involved in game development, and the fun of testing and doing Q&A for games.




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633: Thomas Steiner on AI in Chrome and the Web

Thomas Steiner from Project Fugu talks with us about AI in Chrome, the small large language model in use, how features like this are rolled out, the ethics and concerns around sending and sharing data, on device vs web APIs, and ideas for use cases and ways to explore AI on the web.




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634: Fabian Kägy on WordPress, Blocks, and Enterprise Dev

Fabian Kägy helps us understand the modern WordPress development process, Gutenberg vs Block editor vs full site editing, building with blocks or pages, what's coming in the Twenty Twenty-Five Theme, and whether the theme authoring process has been made too difficult in 2024?




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635: Jeff Robbins and Visibox as an Instrument for Video

Jeff Robbins stops by to talk about his software, Visibox, that was used at Frostapalooza for presenting video at the concert, what it's like building an app with Electron, how it's distributed, how files are used and managed, and how he supports hardware devices inside Electron.




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636: W Hot Drama Week (WordPress, WP Engine, and Web Components – Oh My!)

We're getting some feelings out about WordPress and Matt Mullenweg vs WP Engine drama, as well as the Web Components conversation that happened this past week.




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637: Approachable Open Source with Brian Muenzenmeyer

Brian Muenzenmeyer joins the show to talk about his book, Approachable Open Source, ways we can make open source easier to get in, important conversations around funding and supporting open source, and whether money helps maintainers deal with burnout or not?




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638: Q&A About Copyright, Jekyll, Joomla, Statamic, and More!

Dave's designing a new tshirt, questions for lawyers about copyrights for code projects, what does the copyright in the footer actually do, what do Dave and Chris require for personal web projects, does Jekyll get updated anymore, the Bob from Hell UX pattern, viewing ads on CNN, what about Joomla or Statamic, and how do paid fonts on the web work?




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639: DX, JSON, XML, HTML, and Databases! Oh My!

How important is the DX of software vs how important is the person showing off the software, Douglas Crockford and JSON, remembering XML, trying to write better HTML for email, new TC39 proposal, workshopping t-shirts, and what do you do if you want a little bit of database on your website?




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Ferrari's Leclerc fined for swearing

Stewards at the Brazilian race summoned Leclerc on Friday, acting on a report from the governing FIA's media delegate and after reviewing a written transcript.




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Could Maini be India's next F1 driver?

India could finally have a driver on the F1 grid after 13 long years.




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‘Our goal is beauty for each,’ says L’Oréal India chief

Aseem Kaushik, who leads the global beauty giant in India, says tech is playing a big part in its personalisation journey




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CEA plans 613 GW RE transmission capacity

Higher generation of renewable energy challenges grid stability




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Keeping track of Scope-3 emissions from supply chains

Gurgaon-based startup OnlyGood FutureTech helps companies measure emissions generated by supply partners




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ADB increases climate finance after US, Japan give world's first sovereign guarantees




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Air quality 'very poor' in Delhi

Delhi’s air quality remains “very poor” with some areas in the “severe” category, despite a slight improvement




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Delhi's air quality remains 'very poor', AQI at 367

The minimum temperature in Delhi was recorded at 18.0 degrees Celsius, 3.7 notches warmer than usual.




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India's climate policies expected to reduce CO2 emissions by around 4 billion tonnes by 2030: Report

The study by Delhi-based independent think tank Council on Energy, Environment and Water (CEEW) said policies for India's power, residential and transport sectors have already saved 440 million tonnes of carbon dioxide (MtCO2) between 2015 and 2020.




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Delhi's air quality remains 'very poor' on November 8

Meanwhile, a thick layer of morning mist and smog blanketed the city as the minimum temperature dropped to 18.1 degrees Celsius, 3.8 degrees above normal; AQI stood at 387




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ARRL November Sweepstakes CW is Nov 2-3




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Rare California Island to be Activated for Armed Forces Day, First Time in 53 Years

On Armed Forces Day, May 1971, 53 years ago, two amateur operators working as WZ6SNI, activated San Nicolas Island, IOTA NA-066. At 61 miles, San Nicolas is the most remote of the Channel Islands off the coast of Southern California and is owned by the US Navy.

Now, weather permitting, Will Costello, WC6DX, has been authorized to be active from San Nicolas Island November 8 - 12, 2024. He is tak...




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Space data fuels India's farming innovation drive

Satellite data has gives an Indian farmer optimal sowing times, weather warnings, and better use of irrigation and pesticides




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Mango growers demand uniform relief of ₹30,000 per acre, fixed prices at tripartite meeting in Krishnagiri




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Over ₹13 crore funds needed to support farmers in drought-affected areas of Nellore, says Collector

Ten in the district have been declared as ‘drought mandals’ by the NDMA; over 50% of crop was lost in Sitaramapuram while 30-40% of crops were lost in the remaining nine mandals




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Paddy MSP up 5.35% to ₹2,300 per quintal as Cabinet clears MSP hikes for 14 kharif crops

MSPs for bajra, arhar dal, maize offer highest margins above production costs; Cabinet nod for Varanasi airport expansion, new Maharashtra port, wind energy projects in Gujarat and T.N., forensic infrastructure development




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90-year-old farmer convicted, sentenced to one-year imprisonment for encroaching 36 guntas of government land in Karnataka

Small and marginal farmers are worried about being punished for encroachment, demand action against influential people who allegedly encroached on government land




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Cabinet clears 7 schemes with ₹ 14,235.30 crore for agriculture sector

Digital Agriculture Mission, which has an outlay of ₹2.817 crore and aims to create a consolidated database on crop data, among initiatives to get nod; schemes to boost nutritional security and livestock production also approved




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Centre announces 3 AI Centres of Excellence focused on healthcare, agri and sustainable cities

The Centres of Excellence will be led by top educational institutions, in consortium with industry partners and startups, Union Education Minister Dharmendra Pradhan said