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Active transcytosis and new opportunities for cancer nanomedicine




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Biomimetic niches reveal the minimal cues to trigger apical lumen formation in single hepatocytes




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Universal chemomechanical design rules for solid-ion conductors to prevent dendrite formation in lithium metal batteries




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Coronavirus pushes education online




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A year-long extended release nanoformulated cabotegravir prodrug




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Mechanism of collective interstitial ordering in Fe–C alloys




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Engineering high-energy-density sodium battery anodes for improved cycling with superconcentrated ionic-liquid electrolytes




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James F. Scott (1942–2020)




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Nature Materials




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Opioid and Hedgehog signalling pathways converge to modulate OA




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Hospitalization for infection on the rise in gout




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GCA relapse common in ustekinumab trial




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Tanezumab improves difficult-to-treat OA




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Physical therapy better than steroids for knee OA




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Finding a unifying SLE expression signature in a sea of heterogeneity




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Targeting adenosine in SSc




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HIF1α blockade reduces kidney injury in lupus nephritis




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Nature Reviews Rheumatology




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Evaluation of glucocorticoid-induced TNF receptor (GITR) expression in breast cancer and across multiple tumor types




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Genetic and clinical correlates of entosis in pancreatic ductal adenocarcinoma




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Adenomyoepithelial tumors of the breast: molecular underpinnings of a rare entity




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<i>RAF1</i> rearrangements are common in pancreatic acinar cell carcinomas




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Mucinous carcinoma with micropapillary features is morphologically, clinically and genetically distinct from pure mucinous carcinoma of breast




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The impact of 2018 ASCO-CAP HER2 testing guidelines on breast cancer HER2 results. An audit of 2132 consecutive cases evaluated by immunohistochemistry and in situ hybridization




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Undifferentiated round cell sarcoma with <i>BCOR</i> internal tandem duplications (ITD) or <i>YWHAE</i> fusions: a clinicopathologic and molecular study




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<i>KRAS</i> amplification in metastatic colon cancer is associated with a history of inflammatory bowel disease and may confer resistance to anti-EGFR therapy




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Modern Pathology




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A methylation functional detection hepatic cell system validates correlation between DNA methylation and drug-induced liver injury




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An analysis of the effect of mu-opioid receptor gene (<i>OPRM1</i>) promoter region DNA methylation on the response of naltrexone treatment of alcohol dependence




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Cost-effectiveness of <i>CYP2C19-</i>guided antiplatelet therapy in patients with acute coronary syndrome and percutaneous coronary intervention informed by real-world data




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Identification of gene modules associated with survival of diffuse large B-cell lymphoma treated with CHOP-based chemotherapy




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A high-resolution <i>HLA</i> imputation system for the Taiwanese population: a study of the Taiwan Biobank




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Combining clinical and candidate gene data into a risk score for azathioprine-associated leukopenia in routine clinical practice




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Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment




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Association of <i>MICA</i>-129Met/Val polymorphism with clinical outcome of anti-TNF therapy and MICA serum levels in patients with rheumatoid arthritis




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The Pharmacogenomics Journal




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A novel vaccine target for malaria




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10 years of biosimilars: lessons and trends




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Publisher Correction: ASPI: a public–private partnership to develop treatments for autism




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Tumours use NETs as physical shields




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Shortening jet-lag recovery




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TRAIL blockade improves heart function




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Gasdermin D inhibitor protects against sepsis




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Targeting CDK12 to treat DM1




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Nature Reviews Drug Discovery




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Publisher Correction: Outcompeting cancer




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Role of RNA modifications in cancer




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Fibroblasts orchestrate tumour initiation




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The duality of human oncoproteins: drivers of cancer and congenital disorders




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Executable cancer models: successes and challenges