Saskatchewan's unemployment rate soared in April due to the COVID-19 economic shutdown but an economist says it's not likely to get much worse.

A Saskatchewan daughter said her mom has been “confined” to her room at a government run health-care facility due to COVID-19. 

Four-time All Pro tight end Rob Gronkowski has agreed to a reunion with Tom Brady. The trade, finalized Tuesday night, brings Gronkowski and a seventh-round pick to Tampa Bay in exchange for a fourth-round selection.

Calgary Flames general manager Brad Treliving will watch Thursday's remote NFL draft and is planning to focus on how his football counterparts deal with the realities of their world during the COVID-19 pandemic.

New England head coach Bill Belichick said not taking a quarterback in the Patriots' first post-Tom Brady draft "wasn't by design."

The space near City Hall will allow weddings celebrations with up to 10 people.

Florist Sam Solis said in 21 years of business, he’s never seen a busier Mother’s Day. He and other florists and bakers are working double time to help fete the mothers of British Columbia.

Tennis courts in Vancouver, along with several other Metro Vancouver municipalities, will be open this weekend as municipalities across Metro Vancouver lift restrictions put in place in March due to the COVID-19 crisis. There are rules for getting out to play, however.

Twenty-five years after meeting Johnny Cash, a Newfoundland musician is trying to track down a photo of the pair.

Matteo Tranchellini and Moreno Monti created a coffee table book called CHICken to showcase the natural beauty of the ubiquitous birds.

It turns out a small black box with a dangling red wire and little blue light investigated by Windsor's bomb squad Tuesday isn't actually dangerous — at least to the living.

It's not often people want to hang onto winter, but a Summerside, P.E.I. woman has kept a piece of it in her freezer for over a decade: a snowball in a ziplock bag.

A New Zealand mail carrier made it her mission to deliver a package that was vaguely addressed to "Phil and Kay," located "opposite Cust pub or thereabouts."

Where are they from? Why are they there? Crates full of steel-toe boots showed up at the Yellowknife dump last week. Now they're almost gone.

Many factors make blacks, especially black men, particularly vulnerable to the coronavirus.

The battle for humanity and solidarity in the post-American world.

A young lady in a small Laotian village is pressured to recant her faith or jeopardize her educational future.

Karla Bell was outside an Orangeville hospital waiting to start her nursing shift when she heard a cry for help from a car in the parking lot. She ran up to find a woman in labour in the passenger seat. Natalie Kalata tells us the incredible story of how this baby was born.

Living on a 10-acre plot of land 100 kilometres outside Toronto, David Stevens thought he and his family were well prepared to ride out the COVID-19 quarantine. But after a call from his mother, he learned that even the best laid plans can go wrong.

The Citizens for an Accountable Mega Hospital Planning Process are in court trying to get leave to appeal a ruling that dismissed their appeal to the Local Planning Appeal Tribunal over the location of the mega-hospital.

Of the 58 people who have died due to COVID-19 in Windsor-Essex, 14 of them were patients at Windsor Regional Hospital's field hospital.

Making a film when you can't leave home means being creative — with everything from the scenery to your cast. C.J. Bernauer talked to Windsor Morning host Tony Doucette about his new short horror film, called 'You're It.'

Late Thursday, Georgia father and son Gregory McMichael and Travis McMichael were arrested in connection with the death of Ahmaud Arbery, a 25-year-old black man.

Villagers placed the bodies of three victims of a deadly gas leak from an LG Polymers plant in southern India at the gates of the site on Saturday and demanded the factory be shut down immediately and its top management arrested.

Justin Young and Justine Manuel in Kamloops, B.C., shaved off their eyebrows as extra incentive to stay home and avoid socializing.

As British Columbians maintain physical distancing recommendations during the COVID-19 pandemic, this year’s Easter celebrations will have to change. In Kamloops, B.C., organizations are working to make sure Easter is as fun and social as it can be. 

Farmers markets throughout B.C.’s Interior and South Coast are ramping up for their spring seasons, but COVID-19 has forced them to make some changes to how they operate. 

A B.C. couple who shaved their eyebrows off in the spirit of forcing themselves to stay at home has tackled another isolation challenge — home haircuts. 

The Coldwater band is calling for federal intervention after Trans Mountain announced it was changing the way it would study the aquifer the First Nation relies on for its drinking water.

Most of the animals at the B.C. Wildlife Park in Kamloops are unfazed by the absence of paying visitors since it closed in March over COVID-19 concerns. But Blue the turkey appears "bummed," staff say.

Nearly a quarter-million more Albertans lost work in April as the economic shutdown due to COVID-19 continued, with young workers — particularly young women — being disproportionately affected.

From age 17, Ana Maria prayed to serve God in Switzerland. While she waited, she became a dance instructor with no idea dance would become her ministry.

For Roberto Ramirez, serving God in missions has been one step of faith after another.

Scott Shellady, TJM Investments

Scott Shellady, TJM Investments

Scott Shellady, TJM Investments

Scott Shellady, TJM Investments

While players are stuck in self isolation, they don’t need to worry about trying to stop Alexander Ovechkin’s “knuckleball” type shot.

Montreal Canadiens goaltender Carey Price has reached out to give support to two boys who lost their parents during the Nova Scotia mass shooting last month.

Just when you thought you watched the best shot of the Brier, another best shot of the Brier appears at the 2020 Canadian men's curling championship being held in Kingston, Ont.

Alberta's Brendan Bottcher defeated Saskatchewan's Matt Dunstone 9-4 in the 1-2 Page playoff game Saturday afternoon to earn a berth in the Tim Hortons Brier final.

When the World Curling Federation cancelled the women's, men's and mixed doubles championships set for March and April, it said it would be discussing potential options including rescheduling the events — perhaps playing them in the fall at one venue. CBC Sports has learned that will no longer be the case.

Colleen Jones, Sidney Crosby among many preeminent local sports figures reacting in the aftermath of Sunday's killing rampage.

The COVID-19 pandemic may be keeping families physically distant, but that doesn't mean you can't show someone you care.

The general field of quantitative biology has advanced significantly on the back of recent improvements in both sequencing technology and proteomics methods. The development of high-throughput, short-read sequencing has revolutionized RNA-based expression studies, while improvements in proteomics methods have enabled quantitative studies to attain better resolution. Here we introduce methods to undertake global analyses of gene expression through RNA and protein quantification in Xenopus embryos and tissues.

Determining the concentration of protein samples generally is accomplished either by measuring the UV absorbance at 280 nm or by reacting the protein quantitatively with dyes and/or metal ions (Bradford, Lowry, or BCA assays). For purified proteins, UV absorbance remains the most popular method because it is fast, convenient, and reproducible; it does not consume the protein; and it requires no additional reagents, standards, or incubations. No method of protein concentration determination is perfect because each is subject to a different set of constraints such as interference of buffer components and contaminating proteins in direct UV determination (A₂₈₀) or reactivity of individual proteins and buffer components with the detecting reagents in colorimetric assays. In cases in which protein concentration is critical (e.g., determination of catalytic rate constants for an enzyme), it may be advisable to compare the results of several assays.

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