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Reconfiguring the endogenous electric field of a wound through a conductive hydrogel for effective exudate management to enhance skin wound healing

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01349B, Communication
Yukun Yan, Yuanyuan Chen, Hanqing Dai, Wanlu Zhang, Ruiqian Guo
In this work, we proposed a mechanism for hydrogel-based dressings to respond to endogenous electric fields through exudate absorption and conducted a verification study using polyacrylamide and sodium alginate (PAM–SA) hydrogels.
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Photoresponsive prodrug-based liposomes for controllable release of the anticancer drug chlorambucil

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01620C, Paper
Xiaoting Wang, Guangtian Suo, Shinan Ma, Chunxi Yang, Chunyan Bao
A photoresponsive lipid prodrug was designed to form nanomedicines for accurate and controllable drug release in response to light irradiation.
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Multimodal layer-by-layer nanoparticles: a breakthrough in gene and drug delivery for osteosarcoma

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01541J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Eugenia Crisafulli, Annachiara Scalzone, Chiara Tonda-Turo, Joel Girón-Hernández, Piergiorgio Gentile
This study explored biodegradable nanoparticles for treating osteosarcoma. Co-delivery of miRNA-34a, doxorubicin, and resveratrol by LbL nanocoating enhanced apoptosis and cell disruption with promise to improve efficacy and reduce drug resistance.
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Scalable fabrication of porous membrane incorporating human extracellular matrix-like collagen for guided bone regeneration

J. Mater. Chem. B, 2024, 12,11142-11155
DOI: 10.1039/D4TB00962B, Paper
Qingyi Wang, Feng Zhou, Tiecheng Qiu, Yiling Liu, Wenxin Luo, Zhanqi Wang, Haiyun Li, E. Xiao, Qiang Wei, Yingying Wu
We fabricated a PCL/hCol membrane with an asymmetric porous structure for guided bone regeneration via nonsolvent-induced phase separation method. It shows superior mechanical and degradation properties, biocompatibility and osteoinductive effect.
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Structural isomerism engineering regulates molecular AIE behavior and application in visualizing endogenous hydrogen sulfide

J. Mater. Chem. B, 2024, 12,11134-11141
DOI: 10.1039/D4TB01617C, Paper
Yaxi Li, Yong-Xiang Wang, Dujuan Liu, Chen-Chieh Ni, Jianming Ni, Jen-Shyang Ni
The isomerization effect on coumarin-based AIEgens was systematically analyzed and further applied to H2S detection.
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Piezoelectric materials for anti-infective bioapplications

J. Mater. Chem. B, 2024, 12,11063-11075
DOI: 10.1039/D4TB01589D, Review Article
Chen Chen, Xin Yang, Yi Liu, Jia Jia, Yiping Li, Xiaohan Dai, Ousheng Liu
This review summarizes recent advances in piezoelectric materials for anti-infective and regenerative therapies. It highlights antibacterial mechanisms and discusses their anti-infective bioapplications.
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Acellular dermal matrix hydrogels promote healing of radiation-induced skin injury in a rat model

J. Mater. Chem. B, 2024, 12,11218-11229
DOI: 10.1039/D4TB00941J, Paper
Xin Liu, Tian Guo, Zhifeng Huang, Sen Chen, Li Chen, Chenyang Li, Tian Tian, Yerong Qian, Lifei Yang, Junxi Xiang, Qiufang Liu, Peng Liu
Using a novel rat model of RISI, the research demonstrates that ADM hydrogel effectively reduces wound area and severity, increases epithelial thickness, and accelerates healing compared to controls.
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Drug-delivery and biological activity in colorectal cancer of a supramolecular porous material assembled from heptameric chromium-copper-adenine entities

J. Mater. Chem. B, 2024, 12,11156-11164
DOI: 10.1039/D4TB01521E, Paper
Sandra Mena-Gutiérrez, Ekain Maiza-Razkin, Jon Pascual-Colino, Marcos J. Araúzo-Bravo, Garikoitz Beobide, Oscar Castillo, Ainara Castellanos-Rubio, Daniela Gerovska, Antonio Luque, Sonia Pérez-Yáñez
Supramolecular metal-organic porous materials as drug delivery systems, modulation of the release kinetics using cholesterol as pore blocking agent and its impact on colorectal cancer cell cultures: cytotoxicity and RNA-seq transcriptomics studies.
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Advances in osteoimmunomodulation of biomaterials after intrabone implantation: focus on surface hydrophilicity

J. Mater. Chem. B, 2024, 12,11089-11104
DOI: 10.1039/D4TB01907E, Review Article
Xinpeng Wei, Linshan Lei, Ling Luo, Ying Zhou, Zheng Zheng, Wenchuan Chen
Hydrophilicity of implantable biomaterials can facilitate osteoimmunomodulation through influencing proteins adsorption, blood clotting, neutrophils activation, macrophages polarization, angiogenesis and osteogenesis to enhance osseointegration.
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Chitosan-functionalized nanobubbles for precision oncology: advances in targeted cancer therapeutics

J. Mater. Chem. B, 2024, 12,11076-11088
DOI: 10.1039/D4TB01930J, Review Article
Vivek Pandey, Tejasvi Pandey
The convergence of nanotechnology and cancer therapeutics has opened new frontiers in the development of advanced drug delivery systems.
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Microfluidic synthesis and accurate immobilization of low-density QD-encoded magnetic microbeads for multiplex immunoassay

J. Mater. Chem. B, 2024, 12,11230-11236
DOI: 10.1039/D4TB01585A, Paper
Zhou Sha, Tianyi Ling, Wenqi Yang, Haosu Xie, Chunnan Wang, Shuqing Sun
Accurate immobilization of microbeads in the gap of nickel patterns.
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A guanidiniocarbonyl-pyrrole functionalized cucurbit[7]uril derivative as a cytomembrane disruptor for synergistic antibacterial therapy

J. Mater. Chem. B, 2024, 12,11105-11109
DOI: 10.1039/D4TB01840K, Communication
Ruixue Han, Kehan Du, Shengke Li, Minzan Zuo, Ponmani Jeyakkumar, Hao Jiang, Leyong Wang, Xiao-Yu Hu
A guanidiniocarbonyl-pyrrole functionalized cucurbit[7]uril derivative as a cytomembrane disruptor has been successfully constructed for synergistic antibacterial therapy.
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Effect of supramolecular peptide hydrogel scaffold charge on HepG2 viability and spheroid formation

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01701C, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Yu Xin, Cosimo Ligorio, Marie O’brien, Richard Collins, Siyuan Dong, Aline F. Miller, Alberto Saiani, Julie E. Gough
Understanding how fibre charge in self-assembling peptide hydrogel networks affect HepG2 cell fate and spheroid formation.
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Nanobiopolymers in cancer therapeutics: advancing targeted drug delivery through sustainable and controlled release mechanisms

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB00599F, Review Article
Shikha Gulati, Nabeela Ansari, Yamini Moriya, Kumud Joshi, Disha Prasad, Gargi Sajwan, Shefali Shukla, Sanjay Kumar, Rajender S. Varma
Nanobiopolymers in cancer therapeutics offer sustainable and targeted drug delivery with controlled release, enhancing treatment efficacy while ensuring sustainability and biodegradability for improved patient care.
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Nanomaterial-mediated photothermal therapy modulates tumor-associated macrophages: applications in cancer therapy

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01928H, Review Article
Yan Li, Yuhao Si, Heng Yin
Nanomaterials for modulating tumor-associated macrophages in photothermal therapy.
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Controlled therapeutic cholesterol delivery to cells for the proliferation and differentiation of keratinocytes

J. Mater. Chem. B, 2024, 12,11110-11122
DOI: 10.1039/D4TB01015A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Krzysztof Berniak, Ahmadreza Moradi, Agata Lichawska-Cieslar, Weronika Szukala, Jolanta Jura, Urszula Stachewicz
The research concept involves investigating how cholesterol endocytosis impacts cells using electrospun fibers as a carrier. We studied keratinocyte proliferation and evaluated gene expression levels for markers of early and late differentiation.
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Development of enzymatically crosslinked natural deep eutectogels: versatile gels for enhanced drug delivery

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01672F, Paper
Liane Meneses, Dimitra Antonia Bagaki, Ana Roda, Alexandre Paiva, Ana Rita C. Duarte
We propose a new injectable eutectogel prepared by enzymatic crosslinking, using NADES, betaine : glycerol (2 : 1), as solvent. The potential of using this material with improved rheological properties as drug delivery system, has also been evaluated.
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Biomaterials Enhancing Localized Cancer Therapy Activated Anti-Tumor Immunity: A Review

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01995D, Review Article
Jipeng Yao, Zhencun Cui, Feifei Zhang, Haidong Li, Longlong Tian
Localized cancer therapy such as radiotherapy, phototherapy, and chemotherapy are precise cancer treatment strategy, aiming to minimize systemic side effect. However, cancer metastasis remains the primary cause of cancer patients’...
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Unravelling the molecular mechanobiology by DNA-Based fluorogenic tension sensor

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01858C, Review Article
Kaushik Pal
Investigation of the biological system reveals many underlying principles that govern the regular life processes. Recently, the analysis of tiny mechanical forces associated with many biological processes revels their significance...
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Enhanced Luminescence and Stability of TFMDSA Nanoparticles via Polymer-Induced aggregation for Bioimaging

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01825G, Paper
Xiang Li, Xue Ren, Yuchao Luo, Haotian Shi, Zhigang Xie, Bin Xu, Wenjing Tian
In recent years, fluorescence imaging occupies a very important position in the life science and biomedical fields. However, achieving nanomaterials for bioimaging with both high fluorescence quantum efficiency and high...
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Polycyclic aromatic polymer nanoparticles show potent infectious particle adsorption capability

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01793E, Paper
Yudai Oishi, Mako Toyoda, Nanami Hano, Chihiro Motozono, Takamasa Ueno, Makoto Takafuji
Nonspecific viral adsorption by polymer nanoparticles is more economical and superior in terms of operating cost and energy efficiency than viral adsorption using virus-specific antibodies and filtration techniques involving size...
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Research Progress of Nitroxide Radical-Based MRI Contrast Agents: From Structure Design to Application

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB02272F, Review Article
Tao Luo, Bo Wang, Runxin Chen, Qi Qi, Ruodai Wu, Shunzi Xie, Hanbing Chen, Jialei Han, Dalin Wu, Shuaishuai Cao
Magnetic resonance imaging (MRI) remains a cornerstone of diagnostic imaging, offering unparalleled insights into anatomical structures and pathological conditions. Gadolinium-based contrast agents have long been the standard in MRI enhancement,...
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Nano-Bio Interactions of Gum Arabic-Stabilized Lanthanide-based Upconverting Nanoparticles: In Vitro and In Vivo Study

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01579G, Paper
Hana Mirmajidi, Hyojin Lee, Niepukolie Nipu, Jith Thomas, Zuzana Gajdosechova, David Kennedy, Jan A. Mennigen, Eva Hemmer
Lanthanide-based nanoparticles (Ln-NPs) are highly valued for their unique optical and magnetic properties, making them useful in various scientific fields, including materials science and biomedicine. This study investigated the use...
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Extracellular matrix mimetic supramolecular hydrogels reinforced with covalent crosslinked mesoporous silica nanoparticles

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB00499J, Paper
Open Access
Aygül Zengin, Shahzad Hafeez, Pamela Habibovic, Matthew Baker, Sabine van Rijt
Here we present a promising strategy to create hybrid, biomimetic supramolecular injectable hydrogels reinforced covalent crosslinked mesoporous silica nanoparticles for tissue engineering applications.
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Surface-Enhanced Raman Scattering for HSP 70A mRNA Detection in the Live Cells Using Silica Nanoparticles and DNA-Modified Gold Nanoparticles

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01514B, Paper
Ju Eun Cho, Dong-Kwon Lim
Real-time monitoring of mRNA in living cells is crucial for understanding dynamic biological processes. Traditional methods such as northern blotting, PCR, and sequencing require cell lysis and do not allow...
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Eco-Friendly Self-Clean Coatings: Fundamentals, Fabrication, Applications, and Sustainability

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01392A, Review Article
Tanaji K. Chavan, Sushanta Kumar K. Sethi
Eco-friendly self-clean coatings have garnered significant attention due to their potential to address environmental concerns while offering remarkable properties. This review explores the dynamic field of such coatings, focusing on...
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Cuproptosis in cancer therapy: mechanisms, therapeutic application and future prospects

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01877J, Review Article
Jiawei Hu, Junfei Zhu, Tao Chen, Yudie Zhao, Qingwen Xu, Yan Wang
Cuproptosis is a regulated form of cell death induced by the accumulation of metal ions and is closely linked to aspects of cellular drug resistance, cellular metabolism, and signalling pathways.
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MnO2-mineralized milk exosomes as a novel nanoplatform for glutathione detection

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01662A, Paper
Xudong Wang, Xue Wu, Jiuheng Shen, Xian Zhao, Peifen Gao, Wantong Zhou, Wenlin An
This study introduces a novel nanoplatform by surface manganese dioxide (MnO2) mineralization of milk exosomes and labelling with curcumin, enhancing their utility in the detection of GSH.
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Functionalities of pH-responsive DNA nanostructures in tumor-targeted strategies

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01883D, Review Article
Liyue Wen, Min Wang
Design and application of various pH-responsive DNA nanostructures for tumor-targeted strategies toward extracellular and intracellular environments are comprehensively reviewed. Their potential and challenges are also critically discussed.
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Fluorescence sensing techniques for quality evaluation of traditional Chinese medicines: a review

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01886A, Review Article
Yanyu Xiao, Hui Wang, Chenxia Gao, Xinyi Ye, Yuting Lai, Meiling Chen, Xiaoliang Ren
We summarized the advantages and advanced applications of fluorescence sensing technology compared with other analytical techniques, as well as the challenges and prospects of current application in the field of TCM quality evaluation.
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Advancing cancer therapy with a heptamethine carbocyanine dye-conjugated radionuclide drug

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01798F, Paper
Mingxing Huang, Weichen Wang, Yingwei Wang, Rang Wang, Lili Pan, Xin Li, Bo Li, Jingsong Zhang, Ruoxiang Wang, Yi Zhang, Rong Tian
Malignant tumors pose substantial treatment challenges due to their heterogeneity, metastatic potential, and therapeutic resistance, underscoring the urgent need for more effective treatment options.
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Bimetallic doped carbon dot nanozymes for enhanced sonodynamic and nanocatalytic therapy

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01916D, Paper
Yandong Huang, Lanting Jia, Shiqi Zhang, Lan Yan, Lei Li
The conventional inorganic semiconductors are not suitable for acting as nanozymes or sonosensitizers for in vivo therapeutic nanomedicine owing to the lack of excellent biocompatibility. Biocompatible carbon dots (CDs) exhibit...
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Recent Advances in Polymer-based Thin-film Electrode for ECoG Applications

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB02090A, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Zhengchen Xiang, Liangtao Yang, Bin Yu, Qi Zeng, Tao Huang, Shuo Shi, Hao Yu, Yi Zhang, Jinglong Wu, Meifang Zhu
Electrocorticography (ECoG) has garnered widespread attention due to its superior signal resolution compared to conventional electroencephalogram (EEG). While ECoG signal acquisition entails invasiveness, the invasive rigid electrode inevitably inflicts damage...
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Will POW bring back great story telling to television?

'Nikkhil Advani's POW shows a director's deft touch and is a promising start of a great story, top notch acting talent and great behind the scenes production team,' says film director Suparn Verma.




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'I didn't like Bani's attitude in Bigg Boss 10'

'Manu and Manveer have a bigger image. They are popular and I could not be compared to them. I was a small face from a small town but I clearly stood apart and contributed a lot to my team.' Navin Prakash explains why he got eliminated from Bigg Boss 10.





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'Not my responsibility to babysit anyone on Bigg Boss 10'

Karan Mehra is happy to get out of Bigg Boss 10.






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Bigg Boss 10: Manveer is season's first finalist!

There are some victories in the house that make you smile along. And Manveer's victory is one of them, says Divya Nair.




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'We should not waste life on something if it doesn't work out'

'The role in Warris is challenging because I have to leave my femininity aside. I have to be snappy like a boy. I worked on my body language and voice modulation. Being a guy is maintenance-free. I let my eyebrows grow and didn't have to bleach or do a facial.' Meet Warris actor Farnaz Shetty.






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PIX: TV actors Karan-Ankita's beautiful Greece holiday

Let us tour Greece with television actors Karan Patel and Ankita Bhargava.