of

Synthesis of bambusurils with perfluoroalkylthiobenzyl groups as highly potent halide receptors

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01746C, Research Article
Open Access
Matúš Chvojka, Hennie Valkenier, Vladimír Šindelář
Four new fluorinated bambusuril macrocycles were prepared to show exceptional high binding affinity towards halide anions in acetonitrile.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Photocatalytic arylation/alkylation of olefins/alkynes via halogen-atom transfer mediated by NHC-BH3

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01562B, Research Article
Xinhan Li, Yao Zhong, Fengsong Tan, Yusong Fei, Xiaohan Zhao, Jianbin Xu, Baomin Fan
A versatile method for radical reductive cross-coupling of iodides and activated olefins under mild conditions, facilitated by NHC-BH3 through photocatalysis, was developed.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Photoinduced cobaloxime catalysis for allylic mono- and diphosphinylation of alkenes with hydrogen evolution

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01638F, Research Article
Aijun Zhang, Miao-Miao Li, Lei Guo, Huaixiang Yang, Jiefei Guo, Da Xu, Wei Ding
A highly efficient allylic radical mono- and diphosphinylation of alkenes with secondary phosphine oxides is developed, via visible-light-induced cobaloxime catalysis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

The reactivity of alkenyl boron reagents in catalytic reactions: recent advances and perspectives

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01703J, Review Article
Ya-Li Feng, Bo-Wen Zhang, Youzhi Xu, Shengnan Jin, Daniele Mazzarella, Zhong-Yan Cao
Recent advances focusing on novel reactivity of alkenyl boron reagents in polar or radical pathways within catalytic reactions by employing transition metal catalysis, organocatalysis have been summarized and discussed.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Impact of boron desymmetrization on supramolecular polymerization of BODIPY dyes

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01848F, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Tobias B. Tischer, Zulema Fernandez, Lorenz Borsdorf, Constantin Daniliuc, Shigehiro Yamaguchi, Soichiro Ogi, Gustavo Fernandez
Supramolecular polymers are often investigated for highly symmetric and planar molecules, such as typically explored BF2-substituted BODIPY dyes . However, it is surprising that the possibility of desymmetrizing the sp3...
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Visible-light mediated selective phosphonylation modification of tryptophan residues in oligopeptides

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6287-6292
DOI: 10.1039/D4QO01028K, Research Article
Wenfang Xiong, Junye He, Jinyao Liu, Peiru Chen, Shiqi Xu, Yipeng Liu, Shiting Chen, Yuanyuan You, Zhenyu Chen, Jinwu Zhao
A direct C2-H phosphonylation strategy driven by visible light for specific modification of tryptophan-containing peptides has been reported, providing a plethora of phosphorylated tryptophan-containing peptides
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Towards the total synthesis of mandelalide B: construction of the tetrahydrofuran/α-hydroxyl lactone fragment

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6353-6357
DOI: 10.1039/D4QO01433B, Research Article
Jia-Lei Yan, Jie Yu, Yingying Cheng, Mingze Yang, Zhengshuang Xu, Tao Ye
A stereocontrolled synthesis of the tetrahydrofuran/α-hydroxy lactone fragment of mandelalide B has been accomplished. The synthesis features a Horner-Wadsworth-Emmons fragment assembly strategy and a highly stereospecific iodine-induced cyclization.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Total synthesis of spiro Ganoderma meroterpenoids spiroapplanatumines B, D, F, and H

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6333-6339
DOI: 10.1039/D4QO01147C, Research Article
Jia-Hao Zhang, Wen-Cai Luo, Wen-Tao Chen, Yu-Tao He, Ya-Jian Hu
The first total synthesis of spiroapplanatumines B, D, F, and H as well as the possibly undiscovered natural product spiroapplanatumine R has been achieved.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Pd-catalyzed S-glycosylation of cysteine-containing peptides at room temperature

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6347-6352
DOI: 10.1039/D4QO01389A, Research Article
Linhua Shen, Franck Le Bideau, Gong Chen, Samir Messaoudi
This study reports the synthesis of thioglycopeptides via a Pd-catalyzed coupling of cysteine-containing peptides with iodoglycals. A variety of cysteine-containing peptides and other thiol nucleophiles including thiosugars and thiophenols were used.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Iridium/palladium dual photocatalysis for oxidative decarboxylative esterification of alcohols using α-keto acids

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6367-6379
DOI: 10.1039/D4QO01452A, Research Article
Subal Mondal, Soumya Mondal, Debabrata Halder, Siba P. Midya, Ankan Paul, Pradyut Ghosh
Herein, we report an unprecedented oxidative decarboxylative C–O cross-coupling reaction for the esterification of feedstock α-keto carboxylic acids and alcohols under mild conditions.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Transition-metal-catalyzed regiodivergent sulfonylation of aziridrines for the synthesis of β-amino sulfones

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6340-6346
DOI: 10.1039/D4QO01376J, Research Article
Qinqiong Zeng, Yujia Gong, Xiaochun He, Xuemei Zhang, Zhong Lian
We developed the first transition-metal-catalyzed, regiodivergent sulfonylation of aziridines, enabling the efficient synthesis of diverse β-amino sulfones under mild conditions with broad substrate compatibility and high regioselectivity.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Structure determination of difficult-to-crystallize organic molecules by co-crystallization of a phosphorylated macrocycle

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6358-6366
DOI: 10.1039/D4QO01498G, Research Article
Heng Li, Zhijin Li, Juli Jiang, Chen Lin, Leyong Wang
This work reported that 37 different difficult-to-crystallize guest molecules were co-crystallized with the host macrocycle F[3]A1-[P(O)Ph]3 at room temperature, and the molecular structures of the guests could be determined by SCXRD.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Phosphine-controlled divergent reactions of MBH-carbonates with azaheptafulvenes: access to o-anilinyl diene and benzazepine derivatives

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6418-6425
DOI: 10.1039/D4QO01298D, Research Article
Wei Hao, Yiwen Zhang, Xiao Han, Zhen Wang, Weijun Yao
A phosphine controlled divergent cascade reaction of MBH-carbonates with azaheptafulvenes was disclosed. PPh3 provided o-aminophenyl diene while PCy3 offered benzazepine derivative through formal [8 + 3] annulation/ring contraction cascade.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

18F-labelling of nitrogen-containing aryl boronates – anti-cancer drug melflufen as a case study

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6411-6417
DOI: 10.1039/D4QO01594K, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Kevin Bajerke, Fredrik Lehmann, Gunnar Antoni, Kálmán J. Szabó
This study addresses the 18F-labelling of nitrogen-containing arenes via copper-mediated radiofluorination (CMRF). In this case study, derivatives/fragments of the anti-cancer drug melflufen were targeted.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Visible light-induced aerobic photooxidative cleavage of C(sp3)–C(sp2) σ-bonds of allylarenes

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6385-6392
DOI: 10.1039/D4QO01243G, Research Article
Jinyu Tang, Xi Zhao, Jinxuan Ni, Yanping Huo, Yang Gao, Xianwei Li, Yan Liu, Keiji Maruoka, Qian Chen
A cleavage of C(sp3)–C(sp2) σ-bonds of allylarenes to aromatic aldehydes and ketones has been achieved via a visible light-induced photocatalysis.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Asymmetric synthesis of (aza)flavanones by the evolution of CarOx ligands

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6444-6449
DOI: 10.1039/D4QO01345J, Research Article
Juan Yang, Wenlong Kong, Mingxin Chang, Jixing Lai, Shengkun Li
Amino-pyridine-oxazoline (NHPyOx) is conceived as an unprecedented model via the core-emulating optimization of CarOx ligands.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Theoretical insights into Pd-catalyzed dual γ-1,1-C(sp3)–H activation of aliphatic carboxylic acids: mechanistic pathways, substituent influence on product selectivity, diastereoselectivity, and additive effects

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6393-6410
DOI: 10.1039/D4QO01451K, Research Article
Jiaoyang Liu, Li-juan Huang, Zeang Sun, Juan Li
DFT calculations were employed to explore the detailed reaction mechanism and the origins of the experimentally observed product, regio-, and diastereoselectivities in the Pd-catalyzed dual-γ-1,1-C(sp3)–H activation of aliphatic carboxylic acids.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

A pillar[5]arene-based three-component supramolecular copolymer for the fluorescence detection of spermine

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6293-6303
DOI: 10.1039/D4QO01470G, Research Article
Open Access
Martina Mazzaferro, Daniele Crisafulli, Francesca Mancuso, Marco Milone, Fausto Puntoriero, Anna Irto, Salvatore Patanè, Valentina Greco, Alessandro Giuffrida, Ilenia Pisagatti, Anna Notti, Melchiorre F. Parisi, Giuseppe Gattuso
A supramolecular copolymer, composed of a bis-pillar[5]arene diacid and complementary alkylidene- and perylene-bisimide-bis-imidazole comonomers, acts as an OFF/ON luminescent sensor for spermine.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Design, synthesis and application of bipyridine-N,N'-dioxide catalysts in asymmetric synthesis of chiral cyclopropanes

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6470-6476
DOI: 10.1039/D4QO01532K, Research Article
Xiaoying Cao, Xue Tian, Minmin Liu, Shi-Wu Li
A novel type of highly efficient chiral C2-symmetric bipyridine-N,N'-dioxide ligands was prepared and successfully applied in the synthesis of optically pure 1,2,3-trisubstituted cyclopropanes.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

A general method for E-selective olefination of acylsilanes with isocyanides via silver catalysis

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6450-6458
DOI: 10.1039/D4QO01528B, Research Article
Xiu-Xia Liang, Dan-Ni Yang, Xiao-Hui Yan, Peng Wang, Man-Yi Han
A silver-catalyzed olefination reaction between acylsilanes and isocyanides is developed, resulting in E-vinylsilanes with good yields and high stereoselectivities.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Visible-light-promoted catalytic epoxidation of alkenes under metal-free conditions

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6437-6443
DOI: 10.1039/D4QO01265H, Research Article
Dabao Tan, Xiaoyan Cai, Lele Zhang, Boyu Liu, Jianbin Zeng, Feiming Li, Zhixiong Cai, Mingqiang Huang, Xiaoping Chen, Shunyou Cai
In this work, we report a method for the synthesis of functionalized epoxy analogues using the synergistic interaction of 4CzIPN and oxygen under visible light stimulation.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Nickel-catalysed enantioselective cross-electrophile coupling reaction with the retention of the β-fluorine atom

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6459-6469
DOI: 10.1039/D4QO01555J, Research Article
Xin-Yi Shi, Xueyuan Yan, Xiaodong Tang, Shi-Jing Zhai, Genping Huang, Jun-An Ma, Fa-Guang Zhang
A nickel-catalysed enantioselective reductive cross-coupling reaction of a new monofluoromethyl building block with acid chlorides is developed to give chiral α-monofluoromethyl acyloin derivatives.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Activation of donor–acceptor cyclopropanes under basic conditions: ring opening of 2-(p-siloxyaryl)cyclopropane 1,1-dicarboxylates with nitro compounds and other C-nucleophiles

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6483-6494
DOI: 10.1039/D4QO01472C, Research Article
Yulia A. Antonova, Andrey A. Tabolin
A new activation mode for donor–acceptor cyclopropanes was proposed and implemented in their reaction with nitro compounds and other common C-nucleophiles.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Electrochemical approach for upgrading the pollutant CS2: three-component N–H thiocarbamylation of sulfoximines

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6477-6482
DOI: 10.1039/D4QO01310G, Research Article
Peng Qian, Wenjing Xiong, Qian Meng, Jinxiu Liu, Xiyuan Li, Liangquan Sheng
We report an electrochemical approach for upgrading the pollutant CS2via the thiocarbamylation of sulfoximines, in which CS2 and amines are incorporated as a readily available source of dithiocarbamate.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Sulfenylation of bioactive maleimides, acrylates and cyclohexenones under ambient organophotocatalysis

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6503-6509
DOI: 10.1039/D4QO01342E, Research Article
Debanjana Bag, Rajjakfur Rahaman, Anindya S. Manna, Subhasis Pal, Rajesh Nandi, Shobhon Aich, Narendra Nath Ghosh, Dilip K. Maiti
A novel visible light-induced sulfenylation of biologically important maleimides, acrylates and cyclohexenones has been developed using cheap and easily available organophotoredox catalyst Eosin Y with thiols under ambient conditions.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Cobalt-catalyzed enantioselective reductive addition of ketimine with cyclopropyl chloride to construct chiral amino esters bearing cyclopropyl fragments

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6311-6318
DOI: 10.1039/D4QO01474J, Research Article
Jiangtao Hu, Tingting Xia, Xianqing Wu, Hongrui Feng, Jingping Qu, Yifeng Chen
Co-catalyzed asymmetric reductive addition of ketimine with cyclopropyl chloride has been realized to access diverse chiral amino esters bearing cyclopropyl fragments with broad functional group tolerance and excellent enantioselectivities.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Recent developments in the ring-opening transformations of gem-difluorocyclopropanes

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6518-6533
DOI: 10.1039/D4QO01583E, Review Article
Leiyang Lv, Junqi Su, Zhiping Li
This review summarizes the advances of gem-F2CPs as fluoroallylic synthons in transition metal-catalysed ring-opening/cross-coupling reactions via single, double or no C-F bond cleavage on the last two years.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Dendron-mediated control over self-assembly of chlorophyll rosettes into columnar vs. discrete aggregates

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6304-6310
DOI: 10.1039/D4QO01629G, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ryo Kudo, Hiroki Hanayama, Balaraman Vedhanarayanan, Hitoshi Tamiaki, Nobuyuki Hara, Sarah E. Rogers, Martin J. Hollamby, Biplab Manna, Koji Harano, Shiki Yagai
By controlling the π-π stacking of chlorophyll supramolecular rosettes through steric hindrance of alkyl dendrons, it become possible to create chlorophyll tubes and discrete rings that resemble to natural chlorophyll assemblies.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Recent advances in asymmetric synthesis of chiral benzoheterocycles via Earth-abundant metal catalysis

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6534-6557
DOI: 10.1039/D4QO01686F, Review Article
Jinhui Cai, Wenting Zhang, Usman Muhammad, Weishuang Li, Yanjun Xie
This review mainly focus on the assembly of chiral benzoheterocycles, such as dihydrobenzofurans, chromans, indolines, tetrahydroquinolines, etc., via Earth-abundant metal-catalyzed (Cu, Fe, Ni, and Ti) asymmetric synthesis in the last few decades.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

A two-step Kinugasa/Conia-ene-type sequential reaction for the asymmetric synthesis of 8-methylene-2,6-diazaspiro[3.4]octane-1,5-diones

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01388C, Research Article
Shanyue Li, Qicai Ma, Bohua Wu, Haowen Ma, Wei Zhou, Qian Cai
A two-step Kinugasa/Conia-ene-type sequential reaction is developed. The process provided a simple and efficient access to chiral 8-methylene-2,6-diazaspiro[3.4]octane-1,5-diones.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Copper-catalyzed alkynyldisulfuration of arynes: an efficient access to unsymmetrical disulfides

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01844C, Research Article
Shuai Huang, Yumin Zhang, Yuekai Li, Chen-Ho Tung, Xin Li, Zhenghu Xu
This article investigates a copper-catalyzed alkynyl disulfuration reaction of aryne formed in situ to synthesize o‑alkynyl aryl disulfides. The transformation proceeds through the in situ generation of aryne, followed by...
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Enantioselective Addition of 3-hydroxyquinolin-2(1H)-one to Isatin and Pyrazole-4,5-dione Derived Ketimines

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01895H, Research Article
Yue Wei, Guishun Bai, Jiamin Wu, Yi Hua, Tao Zhang, Congyong Yue, Hong Wang, Xiaoze Bao
The enantioselective reactivity of 3-hydroxyquinolin-2(1H)-ones was developed through their addition to isatin and pyrazole-4,5-dione derived ketimines, affording novel architectures featuring multiple natural products scaffolds in high yield with excellent enantioselectivities....
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

DABSO-Mediated Pummerer Reaction Enables One-Pot Synthesis of Pyrroloquinolines for Accessing Marinoquinolines: Mechanistic, Photophysical and Pharmacological Investigations

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01512F, Research Article
Rahimuddin Khan, Dipun Kumar Penthi, Aditi Chatterjee, Chandrakanta Sahoo, Shanti Gopal Patra, Viswanathan Arun Nagaraj, Tabrez Khan
A new one-pot acid- and exogenous oxidant-free synthesis of pyrrolo[2,3-c]quinolines has been developed. The strategy involves chemoselective reduction of the 3-(2-nitrophenyl)-1H-pyrroles (pyrrolnitrin derivatives) and subsequent DABSO-facilitated Pummerer reaction in the...
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Charge Transfer Complex Enabled Mechanochemical Synthesis of Chalcogenoacetylenes via Alkynyl Radicals

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01827C, Research Article
Open Access
Fang Tan, Chang-Zhen Fang, Bing-Sheng Qiu, He Sheng, Yong-Liang Tu, Xiang-Yu Chen
Mechanochemistry has become an appealing strategy to enable numerous organic transformations. While significant advances have been achieved, the radical coupling reaction under mechanochemical conditions is still in its infancy. In...
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Copper(II)-catalyzed synthesis of sulfonyl-functionalized quinone-fused cyclopenta[b]indoles via four-component cascade annulation

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01560F, Research Article
Hong Xu, Jie Liao, Fei Ren, Chuan-Rong Zhou, Xiao-Zhuo Liu, Yao Xiao, Dong-Wei Hang, Fuyu Li, Bei Wang, Ji-Yu Wang
Through crucial selective radical tandem process and intramolecular nucleophilic addition, a facile copper-catalyzed four-component cascade has been realized to selectively construct novel sulfonyl-functionalized quinone-fused cyclopenta[b]indole.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Regio- and stereoselective azidation of activated N-allenamides: an entry to α, β, γ and δ-amido-azides

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01802H, Research Article
Dorian Schutz, Maxime Hourtoule, Laurence Miesch
A totally controlled regiodivergent azidation of activated N-allenamides is described, offering a broad range of diverse functionalized amido-azide derivatives.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Catalyst-free C–H methylation of heteroarenes enabled by electron donor–acceptor complex photoactivation

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01309C, Research Article
Jiayang Wang, Baoer Shao, Haixia Ge, Huiyu Xue, Xiangyuan Ding, Yuqi Li, Peiyao Sheng
A visible-light-induced direct C–H methylation of heterocycles (including quinoxalinones, pyrazinones, quinolinones and coumarins) with methylamines via EDA complex photoactivation was developed.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Folding of a dynamic macrocyclic system to stabilize its cation radical state

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01566E, Research Article
Arnab Dutta, Krzysztof Dzieszkowski, Marco Farinone, Łukasz Orzeł, Krzysztof Kruczała, Monika Kijewska, Miłosz Pawlicki
A precisely designed π-extended system responds to different stimuli by folding the structure, which prevents overoxidation and stabilizes the cation radical.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Facile single-step synthesis of pentaaryl-substituted pyrano[3,2-b]pyrrol-5(1H)-ones showing aggregation-induced emission

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01600A, Research Article
Yongfeng Wang, Ruijun Chu, Yanxiao Wang, Mengyuan Zhou, Yuan Chen, Cheng Xu, Jingyu Sun, Guodong Yin
A novel class of heterocyclic AIEgens has been synthesized via a multicomponent reaction of isatins, 2,3-diaryl cyclopropenones, and alkyl bromides.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

A Stereoselective Organocatalyzed C-Glycosylation of Indole: Implications of Acceptor-Catalyst-Donor Interaction

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01873G, Research Article
Lihuang Xie, Wenchao Liu, Zhenbo Guo, Qinbo Jiao, Xiaomin Shen, Tianfei Liu, Chunfa Xu
A stereoselective pyridinium hexafluorophosphate-catalyzed C-glycosylation of indole is presented, featuring the plausible formation of a catalyst-acceptor complex and a crucial H-bond between the indole N-H and the oxygen at C6...
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Catalytic asymmetric synthesis of chiral sulfilimines via S-C bond formation

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01963F, Highlight
Yingying Shi, Shuiyun Zheng, Jiapian Huang, Fu-Sheng He, Min Yang, Jie Wu
As the aza-analogues of sulfoxides, sulfilimines bearing S(IV) stereogenic centers hold tremendous potential in synthetic chemistry and medicinal chemistry. However, the catalytic asymmetric synthesis of chiral sulfilimines are much less...
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Thiocyanoalkylation of Alkenes via Dual Photoredox and Copper Catalysis

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01864H, Research Article
Xu Wang, Bi-Yin Xiao, Qi-Xuan Jiang, Wei Huang, Feng-Hua Zhang
Organic thiocyanates are commonly used as an essential organic synthesis intermediate and widely present in various drug molecules and bioactive molecules. Herein, a copper and photoredox catalyzed thiocyanoalkylation reaction of...
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Nickel-catalyzed reductive 1,2-alkylarylation of alkenes via a 1,5-hydrogen atom transfer (HAT) cascade

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01875C, Research Article
Xi Chen, Qiang Wang, Xiao-Ping Gong, Rui-Qiang Jiao, Xue-Yuan Liu, Yong-Min Liang
A nickel-catalyzed 1,2-alkylarylation of alkenes has been developed, leveraging amidyl radical-triggered 1,5-HAT with electrophiles as functionalizing reagents.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Iridium-catalyzed asymmetric cascade allylation/lactonization of methyl salicylates: enantioselective construction of chiral benzodioxepinones

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01771D, Research Article
Bendu Pan, Yunru Wu, Yaqi Zhang, Xiaobo He, Long Jiang, Liqin Qiu
An efficient asymmetric cascade allylation/lactonization of methyl salicylates is achieved. The utilization of chiral-bridged biphenyl phosphoramidite ligand resulted in good results for the construction of a wide range of chiral benzodioxepinones.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Stereocontrolled synthesis of heterocycles from unactivated alkynes by photoredox/nickel dual-catalyzed cyclization

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01627K, Research Article
Bo-Rong Leng, Feng Yang, Jin-Lian Bai, Yu-Wen Huang, Qing-Quan Liu, Ping Wei, De-Cai Wang, Yi-Long Zhu
We report a nickel/photoredox dual catalysis method for synthesizing heterocyclics from unactivated alkynes and aryl iodides, offering a direct, selective, and green alternative to traditional synthesis with potential in medicinal chemistry.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Magic effect of diphenylprolinol silyl ether for the enantioselective allenation of 2-alkynals

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00984C, Research Article
Guolin Wu, Zhen Liu, Shiwen Fan, Wenyao Li, Xue Zhang, Hui Qian, Shengming Ma
Chiral diphenylprolinol silyl ethers have been successfully identified for the enantioselective allenation reaction of terminal alkynes and 2-alkynals, delivering a diverse set of chiral allenynes with high efficiency.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Metal–ligand cooperation and synergistic palladium catalysis for the dual ligand system [2,2'-bipyridin]-6(1H)–one/PCy3: milder conditions for the undirected C–H arylation of arenes

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01877J, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Cintya Pinilla, Mario García-Zarza, Ana C. Albéniz
The mixture of Pd(OAc)2 and two ligands segregate into distinct active species working synergistically for the C–H arylation of simple arenes.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Palladium-catalyzed cascade decarboxylative cyclization of alkyne-tethered aryl iodides with o-bromobenzoic acids for the synthesis of fused isoquinolinones

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01573H, Research Article
Zhaolin Quan, Yubo Duan, Zhengkai Chen
A straightforward approach for the preparation of fused isoquinolinone derivatives via palladium-catalyzed cascade decarboxylative cyclization of alkyne-tethered aryl iodides with o-bromobenzoic acids is described.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Mechanism and origins of regioselectivity of selenium-catalyzed allylic amination reactions

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01794C, Research Article
Xiaoxiao Hu, Dengmengfei Xiao, Yu Chen, Yi Lu, Zhihan Zhang, Peiyuan Yu
The mechanism of selenium-catalyzed allylic amination reactions with different ligands has been explored using density functional theory calculations.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article

of

Synthesis of oxa-bridged carbocycles via rhodium/Lewis acid catalyzed [3 + 3] and [4 + 3] cycloadditions of carbonyl ylides with donor–acceptor strained carbocycles

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01831A, Research Article
Jiale Li, Lingfei Wang, Pei-Nian Liu, Xingguang Li
A method for cooperative rhodium/Lewis acid-catalyzed cycloadditions of carbonyl ylides with donor–acceptor (D–A) strained carbocycles is described. It affords structurally diverse oxa-bridged carbocycles with high efficiency and stereoselectivity.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry


Full Article