ey A Man Before His Time: The Unsung Story of Freydun Atouraya By www.atour.com Published On :: Thu, 03 Mar 2016 09:10:00 UT A Man Before His Time: The Unsung Story of Freydun Atouraya Full Article National News [USA Canada Europe Australia]
ey Brand Alley brings logistics in-house with the help of Scurri By postandparcel.info Published On :: Wed, 21 Aug 2024 09:55:34 +0000 BrandAlley, an off-price premium and luxury brand e-tailer in the UK and France, has driven improved business performance by taking full control of its customer delivery proposition – from dispatch to customer notifications – in partnership with Scurri, the delivery management platform. Full Article E-Commerce Parcel Retail
ey ZigZag Survey proves that customers can come round to the idea of paid returns By postandparcel.info Published On :: Mon, 30 Sep 2024 10:21:27 +0000 Returns specialist ZigZag has published the results of a survey which indicates that one-off fees for returns are preferable to price rises on items among consumers. Full Article E-Commerce Parcel Retail Sustainability
ey The Boycott Turkey Campaign By www.atour.com Published On :: Fri, 30 Apr 2010 11:48:00 UT The Boycott Turkey Campaign Full Article Armenian Assyrian and Hellenic Genocide News
ey CRISPR Immune Cells Not Only Survive, They Thrive After Infusion Into Cancer Patients By scienceblogs.com Published On :: Thu, 06 Feb 2020 19:52:53 +0000 CRISPR Immune Cells Not Only Survive, They Thrive After Infusion Into Cancer Patients In the first-ever (sanctioned) investigational use of multiple edits to the human genome, a study found that cells edited in three specific ways and then removed from patients and brought back into the lab setting were able to kill cancer months after their original manufacturing and infusion. This is the first U.S. clinical trial to test the gene editing approach in humans, and the publication of this new data today follows on the initial report last year that researchers were able to use CRISPR/Cas9 technology to successfully edit three cancer patients' immune cells. The ongoing study is a cooperative between Tmunity Therapeutics, the Parker Institute for Cancer Immunotherapy, and the University of Pennsylvania. Patients on this trial were treated by Edward A. Stadtmauer, MD, section chief of Hematologic Malignancies at Penn, co-lead author on the study. The approach in this study is closely related to CAR T cell therapy, in which patient immune cells are engineered to fight cancer, but it has some key differences. Just like CAR T, researchers in this study began by collecting a patient's T cells from blood. However, instead of arming these cells with a receptor against a protein such as CD19, the team first used CRISPR/Cas9 editing to remove three genes. The first two edits removed a T cell's natural receptors so they can be reprogrammed to express a synthetic T cell receptor, allowing these cells to seek out and destroy tumors. The third edit removed PD-1, a natural checkpoint that sometimes blocks T cells from doing their job. Once the three genes are knocked out, a fourth genetic modification was accomplished using a lentivirus to insert the cancer-specific synthetic T cell receptor, which tells the edited T cells to target an antigen called NY-ESO-1. Previously published data show these cells typically survive for less than a week, but this new analysis shows the edited cells used in this study persisted, with the longest follow up at nine months. Several months after the infusion, researchers drew more blood and isolated the CRISPR-edited cells for study. When brought back into the lab setting, the cells were still able to kill tumors. The CRISPR-edited T cells used in this study are not active on their own like CAR T cells. Instead, they require the cooperation of a molecule known as HLA-A*02:01, which is only expressed in a subset of patients. This means that patients had to be screened ahead of time to make sure they were a match for the approach. Participants who met the requirements received other clinically-indicated therapy as needed while they waited for their cells to be manufactured. Once that process was completed, all three patients received the gene-edited cells in a single infusion after a short course of chemotherapy. Analysis of blood samples revealed that all three participants had the CRISPR-edited T cells take root and thrive in the patients. While none responded to the therapy, there were no treatment-related serious adverse events. CRISPR technology has not previously been tested in humans in the U.S. so the research team had to move through a comprehensive and rigorous series of institutional and federal regulatory approval steps, including approval by the National Institutes of Health's Recombinant DNA Research Advisory Committee and review by the U.S. Food and Drug Administration, as well as Penn's institutional review board and institutional biosafety committee. The entire process required more than two years. Researchers say these new data will open the door to later stage studies to investigate and extend this approach to a broader field beyond cancer, several of which are already planned at Penn. sb admin Thu, 02/06/2020 - 14:52 Categories Life Sciences Full Article
ey Caves Valley to host new LPGA international event in 2014 By www.washingtonexaminer.com Published On :: Sat, 26 Jan 2013 05:00:00 GMT Caves Valley Country Club in Owings Mills, Md. will be the host of a first-of-its-kind event next year on the LPGA Tour. On Friday the tour announced it will establish the International Crown, a biennial, global match-play competition. Full Article
ey Locals Freed, Katz win IJGT event in Hershey By www.washingtonexaminer.com Published On :: Thu, 16 May 2013 04:00:00 GMT Evan Katz, 14, of the District won his first International Junior Golf Tour event, last weekend in Hershey, Pa. / Courtesy photo Full Article
ey Desperate parents turn to magnetic therapy to help kids with autism. They have little evidence to go on By www.latimes.com Published On :: Thu, 5 Sep 2024 10:00:44 GMT MERT is being marketed to families of children with autism. Providers suggest the treatment has been thoroughly studied, but there is little evidence to date of its efficacy. Full Article
ey Wildfires can release more energy than an atomic bomb. No wonder they look apocalyptic By www.latimes.com Published On :: Sun, 22 Sep 2024 10:00:07 GMT Uncontrolled wildfires can be powerful enough to generate their own weather. Full Article
ey Study finds Central Valley residents continually exposed to 'toxic soup' of pesticides By www.latimes.com Published On :: Mon, 30 Sep 2024 12:00:19 GMT A new study found that as Central Valley residents go about their day, they regularly breathe in pesticides, including one banned in California. Full Article
ey Valley fever is a growing risk in Central California; few visitors ever get a warning By www.latimes.com Published On :: Wed, 2 Oct 2024 10:00:35 GMT As the range and incidence of valley fever grows, public health officials are struggling to warn visitors of the risk. Full Article
ey As bird flu outbreaks rise, piles of dead cattle become shocking Central Valley tableau By www.latimes.com Published On :: Sun, 20 Oct 2024 10:00:44 GMT Although California dairy farmers had heard about the H5N1 bird flu before it hit, none was prepared for the devastation it would cause in some herds. Full Article
ey Key takeaways from our investigation into the science behind an alternative autism therapy By www.latimes.com Published On :: Thu, 24 Oct 2024 17:50:49 GMT Here are the key takeways from The Times' yearlong investigation into the science behind magnetic resonance therapy, or MERT, as a therapy for autism. Full Article
ey Berkeley startup wins government award to develop radiation and lead poisoning treatment By www.latimes.com Published On :: Thu, 31 Oct 2024 10:00:34 GMT Few drugs are available to treat heavy metals that enter the body, either from lead poisoning or nuclear fallout. A UC Berkeley startup hopes to change that. Full Article
ey Bradley Beal, Cartier Martin have face-to-face collision in practice By www.washingtonexaminer.com Published On :: Fri, 22 Feb 2013 05:00:00 GMT With the Jordan Crawford situation taken care of, the Wizards can turn their attention back to the court, where Bradley Beal and Cartier Martin both aren’t expected to miss any time following a yucky face-to-face collision during Thursday’s practice. Full Article
ey Bradley Beal crisp in return after six-game absence By www.washingtonexaminer.com Published On :: Mon, 18 Mar 2013 04:00:00 GMT Bradley Beal looked like himself again in his first minutes back on the court in a 127-105 victory over Phoenix on Saturday following six missed games with a sprained left ankle. Full Article
ey Bradley Beal proud of rookie season despite injuries By www.washingtonexaminer.com Published On :: Fri, 05 Apr 2013 04:00:00 GMT Bradley Beal wasn’t going to let some discomfort in his ankles keep him off the court. But that determination to play through the pain probably helped to end his rookie season prematurely. Full Article
ey Bradley Beal finishes third in NBA rookie of the year race By www.washingtonexaminer.com Published On :: Wed, 01 May 2013 04:00:00 GMT After it looked for a time like Bradley Beal might just threaten Portland Trail Blazers point guard Damian Lillard for 2013 NBA rookie of the year, the Wizards shooting guard ultimately finished third after the latter portion of his season was racked by injuries. Full Article
ey Trump to host screening of Sound of Freedom at his New Jersey golf club By www.washingtonexaminer.com Published On :: Thu, 13 Jul 2023 20:40:15 GMT Former President and current GOP presidential front-runner Donald Trump has announced he will host a screening of the movie Sound of Freedom at his own golf course in New Jersey. Full Article
ey Trump plans to raise money in California in the aftermath of felony conviction By www.latimes.com Published On :: Fri, 31 May 2024 16:51:37 GMT Former President Trump is scheduled to headline fundraisers in San Francisco, Beverly Hills and Newport Beach next week after his felony convictions. Full Article
ey In Silicon Valley, more support for Trump is trickling in. Is it a big threat to Biden? By www.latimes.com Published On :: Sat, 8 Jun 2024 00:47:57 GMT In the deeply Democratic Silicon Valley, there are some defectors. They're setting their sights — and their money — on Trump in the 2024 election. Full Article
ey Many California voters get their info from social media, even if they don't trust it, poll shows By www.latimes.com Published On :: Tue, 18 Jun 2024 10:00:50 GMT A new poll shows that California voters are increasingly moving to social media, such as TikTok, for election information. Full Article
ey Why some Silicon Valley investors are backing the Trump-Vance campaign By www.latimes.com Published On :: Thu, 18 Jul 2024 18:31:21 GMT Some Silicon Valley investors are vocally backing Trump due to concerns about how the government is regulating cryptocurrency, its policies on AI and the threat of an increase in capital gains taxes. Full Article
ey This controversial California AI bill was amended to quell Silicon Valley fears. Here's what changed By www.latimes.com Published On :: Fri, 16 Aug 2024 22:24:58 GMT SB 1047 would require AI firms to share their safety plans with the attorney general upon request and face penalties if catastrophic events happen. Full Article
ey Opinion: Silicon Valley is maximizing profit at everyone's expense. It doesn't have to be this way By www.latimes.com Published On :: Fri, 30 Aug 2024 10:00:28 GMT Big Tech titans such as Elon Musk and Reid Hoffman are divided between Kamala Harris and Donald Trump but all too united in their selfish aims. We need a new model. Full Article
ey Gov. Gavin Newsom vetoes AI safety bill opposed by Silicon Valley By www.latimes.com Published On :: Sun, 29 Sep 2024 20:36:24 GMT Gov. Gavin Newsom vetoed AI safety bill SB-1047, which was opposed by tech companies including ChatGPT maker OpenAI and Facebook parent company Meta. Full Article
ey Opinion: The risks of sharing your DNA with online companies aren't a future concern. They're here now By www.latimes.com Published On :: Mon, 21 Oct 2024 10:06:55 GMT Turmoil at 23andMe, and a lawsuit alleging that GEDmatch shares data with Facebook, highlights how far your genetic information could travel without your consent. Full Article
ey AI startup funding hit a record in the L.A. area last quarter. Here's who got the most money By www.latimes.com Published On :: Fri, 8 Nov 2024 11:00:01 GMT L.A.-area startups received $1.8 billion in the third quarter, the highest quarterly amount for the region, according to CB Insights. Most of it went to a single company. Full Article
ey eBooks: Key Tools for Scientific Advancement By www.the-scientist.com Published On :: Thu, 24 Oct 2024 13:49:55 GMT Serving as a bridge between traditional textbooks and peer-reviewed journal articles, ebooks allow scientists to efficiently learn about new findings or fields. Full Article Research Products Blog
ey 'Honey Badger' Tyrann Mathieu leaving a sour taste to some By www.washingtonexaminer.com Published On :: Thu, 25 Apr 2013 04:00:00 GMT The Redskins will have a chance to draft LSU corner Tyrann Mathieu. Two years ago, that would have been an exciting possibility. Now? After missing last season because he was kicked off the team, reportedly for multiple positive drug tests? It's far from a no-brainer and, really, it depends on your philosophy. Full Article
ey New Jersey politician refuses to resign after alleged hit-and-run By www.washingtonexaminer.com Published On :: Thu, 18 Aug 2022 18:47:20 GMT A Jersey City councilwoman refused to step down from office Wednesday night amid outcry over an alleged hit-and-run last month. Full Article
ey Greyhound bus accident leaves more than a dozen injured: Police By www.washingtonexaminer.com Published On :: Sun, 06 Aug 2023 02:41:25 GMT More than a dozen people sustained injuries in an incident involving a Greyhound bus in Georgia, which local authorities said flipped on its side when one of the vehicle's tires blew out. Full Article
ey New Jersey trains delayed due to loose bull on the tracks By www.washingtonexaminer.com Published On :: Thu, 14 Dec 2023 17:39:40 GMT Commuters in Newark, New Jersey, were subject to delays Thursday morning after a bull got loose on the tracks of Newark Penn Station. Full Article
ey How to Identify Long Tail Keywords for SEO Success By www.rssfeedsgenerator.com Published On :: Tue, 18 Nov 2014 14:42:15 +0000 Long tail keywords have taken on a greater importance in organic search, especially with the ever-increasing momentum of mobile users. Whether driving traffic to your website, or promoting a PPC ad campaign, the value of long tail keywords create better targeted action for your marketing and sales funnels. Google’s Hummingbird engine has a conversational search […] Full Article eBusiness Tips keyword research tips search engine ranking website optimization
ey Should I stay away from highly competitive keywords? By www.rssfeedsgenerator.com Published On :: Mon, 01 Jun 2015 12:20:49 +0000 If you’ve used Google’s Keyword Tool, you’ve probably seen the column called “Competitiveness,” with levels low, medium, and high. The low. medium, and high are based on the competitiveness of a keyword among paid search advertisers. The more advertisers are bidding on a keyword, the higher the competitiveness. By itself, paid search competitiveness tells you […] Full Article eBusiness Tips keywords research tips targeted keywords targeted traffic
ey Futuro Women`s Beyond Support Pantyhose Reinforced Toe. By www.newlook.com.sg Published On :: Thu, 2 Oct 2003 16:11:50 GMT Futuro women medical pantyhose. Firm compression 20-30mmHg (class 2). Improve circulation and reduce discomfort from leg fatigue, ankle swelling and other venous insufficiencies. For post surgical patients. Full-cut panty with control top for firming and shaping. Reinforced toe and heel (RHT). Comfort waistband. Manufacturer guarantee. Sizes S,M,L. See Sizechart. Price: USD49.29 Full Article
ey Futuro Women`s Beyond Support Pantyhose French Cut. By www.newlook.com.sg Published On :: Thu, 2 Oct 2003 16:11:50 GMT Futuro women medical pantyhose, mild compression 8-15mmHg (class 1). Improve circulation and reduce discomfort from leg fatigue, ankle swelling and other venous insufficiencies. Enhanced toe with run gaurd. Ultra sheer. Soft and silky. French cut lace panty design. Comfort waistband. Manufacturer guarantee. Sizes S,M,L. See Sizechart. Price: USD35.40 Full Article
ey Futuro Women`s Beyond Support Knee Highs. By www.newlook.com.sg Published On :: Thu, 2 Oct 2003 16:11:50 GMT Futuro women medical kneehigh. Improve circulation and reduce discomfort from leg fatigue, ankle swelling and other venous insufficiencies. Mild (light) compression (8-15mmHg). Ultra sheer, soft, silky, comfortable material. Enhanced toe with run guard and reinforced heel. Comfort band. With manufacturer guarantee. Sizes S,M,L. See Sizechart. Price: USD18.02 Full Article
ey OEM Oval Cat Eye Fashion Bracelet. By www.newlook.com.sg Published On :: Fri, 3 Nov 2006 16:11:51 GMT Eleven white oval-shaped cat eye gemstones forming fashion bracelet. Shiny silver-plated chain and clips. Known to ward off evils and avoid catastrophe. Size: 6.50 inches in length. Non-detachable hinge-joint. White color only. Price: USD15.09 Full Article
ey Delivery Of Guitars and Keyboards By www.nativeamericanmusicfund.com Published On :: Wed, 17 Dec 2014 15:43:00 +0200 We have had two "Give Away" parties. We are so happy we have been able to raise over $10,000 to purchase instruments. We have some funds left over that we will be hosting some weekend music workshops. If there are any of you that want to come and donate us a day, please let us know. We now have instruments in our hands and in our homes. So we are now ready to play. Full Article Blog
ey New collection: Oval Cat Eye Fashion Bracelet By www.newlook.com.sg Published On :: Sat, 4 Nov 2006 08:07:50 +0800 Eleven white oval-shaped cat eye gemstones forming fashion bracelet. Shiny silver-plated chain and clips.Known to ward off evils and avoid catastrophe.Size: 6.50 inches in length. Full Article
ey Oro Valley Fall Foodie & Art Festival By www.tucsonweekly.com Published On :: Thu, 07 Nov 2024 04:00:00 -0700 The Southern Arizona Arts & Cultural Alliance in partnership with Tucson Foodie, hosted the first Oro Valley Fall Foodie & Art Festival on Oct. 26 and Oct. 27 at the Oro Valley Marketplace. The event featured arts, food and fall festivities… Full Article Arts & Culture/Arts: Feature
ey Where to Shop: Boo Radley's By www.inlander.com Published On :: Wed, 18 Sep 2024 01:30:00 -0700 Across from the fountain at Riverfront Park, you might notice a collection of fun oddities and decor in the windows of the colorful gift store Boo Radley's… Full Article Lifestyle
ey A narrower Sprague Avenue now connects Spokane Valley City Hall and Balfour Park By www.inlander.com Published On :: Thu, 31 Oct 2024 01:30:00 -0700 Spokane Valley has finished its nearly $4.6 million Sprague Avenue stormwater and multimodal project, which reduced the road from five to three lanes between North University Road and North Herald Road, where Balfour Park and Spokane Valley City Hall are located… Full Article Local News
ey Spokane rental units are required to be registered, but not everyone knows that; now they might have to pay the fee By www.inlander.com Published On :: Thu, 07 Nov 2024 01:30:00 -0800 Whether you agree with it or not, Spokane's rental registry is law… Full Article Local News
ey Don't stay glued to your porch this summer, visit the honey bucket with the Melvins By www.inlander.com Published On :: Thu, 14 Jul 2022 01:30:00 -0700 Helmed by Buzz Osborne, the Melvins have helped codify the heavy music lexicon since 1983… Full Article Music/Music News
ey Burke, Idaho: Wedged between mountains, the Silver Valley mine town's history of rich resources still echoes down the canyon By www.inlander.com Published On :: Thu, 31 Oct 2024 01:30:00 -0700 Crammed in a narrow canyon of North Idaho's Silver Valley, in perhaps one of the most inconvenient but also beautiful places for a hub of human habitation, are the rusted remains of a once-lively mountain mine town… Full Article Arts & Culture
ey Gen Heywood's photography exhibition at Gonzaga University Urban Art Center explores the potency of two American icons By www.inlander.com Published On :: Thu, 31 Oct 2024 01:30:00 -0700 It's a scary time of year, but not because of Halloween… Full Article Arts & Culture
ey Spokane artist Chris Bovey opens Vintage Print + Neon storefront, studio and workshop in the Garland District By www.inlander.com Published On :: Thu, 29 Sep 2022 01:00:00 -0700 Chris Bovey's new shop on Garland Avenue isn't technically open on Tuesday, but it's too enjoyably warm and sunny on a late September afternoon to keep the roll-up door along the sidewalk closed… Full Article Culture/Arts & Culture
ey We asked more than 65 local politicians if they were vaccinated for COVID-19. Here's what they said By www.inlander.com Published On :: Thu, 26 Aug 2021 01:40:00 -0700 Before we start, let's get this out of the way: No, it is not a HIPAA violation to ask someone if they've been vaccinated for COVID-19… Full Article News/Local News