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Intercellular lipid-cored, hectorite nanoplatelet-armored pickering emulsions with enhanced transdermal delivery and epidermal hydration

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01610F, Paper
Boryeong Lee, Lakshmishri Prabakaran, Minkyoung Jang, Song Hua Xuan, Kyounghee Shin, Sung Ho Lee, Jin Woong Kim
An intercellular lipid-cored, hectorite nanoplatelet-armored Pickering emulsion system is proposed to enhance dermal penetration and moisture retention.
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Evaluation of Alkyl Chain Length and Photocatalytic Antibacterial Performance of Cation g-C3N4

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01118J, Paper
Junling Leng, Xuanwei Liu, Yin Xu, shien zhu, Yuefei Zhang, Zhongbing Tan, Xiaofei Yang, Jia-En Jin, YuFeng Shi, Fan Hongying, Yi Yang, Hang Yao, Yu Zhang, Hui Chong, Chengyin Wang
Several cation graphite carbon nitrides (g-C3N4-(CH2)n-ImI+) were synthesized by chemically attaching imidazolium appended alkane chains with different lengths (n = 2, 4, 8, 12 and 16) to g-C3N4. Introduction of...
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Reconfiguring the endogenous electric field of a wound through a conductive hydrogel for effective exudate management to enhance skin wound healing

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01349B, Communication
Yukun Yan, Yuanyuan Chen, Hanqing Dai, Wanlu Zhang, Ruiqian Guo
In this work, we proposed a mechanism for hydrogel-based dressings to respond to endogenous electric fields through exudate absorption and conducted a verification study using polyacrylamide and sodium alginate (PAM–SA) hydrogels.
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Multimodal layer-by-layer nanoparticles: a breakthrough in gene and drug delivery for osteosarcoma

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01541J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Eugenia Crisafulli, Annachiara Scalzone, Chiara Tonda-Turo, Joel Girón-Hernández, Piergiorgio Gentile
This study explored biodegradable nanoparticles for treating osteosarcoma. Co-delivery of miRNA-34a, doxorubicin, and resveratrol by LbL nanocoating enhanced apoptosis and cell disruption with promise to improve efficacy and reduce drug resistance.
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Sodium lanthanide tungstate-based nanoparticles as bimodal contrast agents for in vivo high-field MRI and CT imaging

J. Mater. Chem. B, 2024, 12,11123-11133
DOI: 10.1039/D4TB01157K, Paper
Open Access
Elisabet Gómez-González, Carlos Caro, Nuria O. Núñez, Daniel González-Mancebo, Jesús D. Urbano-Gámez, Maria L. García-Martín, Manuel Ocaña
NaLn(WO4)2 (Ln = Dy or Ho) nanoparticles functionalized with polyacrylic acid exhibit excellent performance as bimodal contrast agents for high-field MRI and X-ray computed tomography bioimaging and show tumor targeting ability through the EPR effect.
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Scalable fabrication of porous membrane incorporating human extracellular matrix-like collagen for guided bone regeneration

J. Mater. Chem. B, 2024, 12,11142-11155
DOI: 10.1039/D4TB00962B, Paper
Qingyi Wang, Feng Zhou, Tiecheng Qiu, Yiling Liu, Wenxin Luo, Zhanqi Wang, Haiyun Li, E. Xiao, Qiang Wei, Yingying Wu
We fabricated a PCL/hCol membrane with an asymmetric porous structure for guided bone regeneration via nonsolvent-induced phase separation method. It shows superior mechanical and degradation properties, biocompatibility and osteoinductive effect.
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Piezoelectric materials for anti-infective bioapplications

J. Mater. Chem. B, 2024, 12,11063-11075
DOI: 10.1039/D4TB01589D, Review Article
Chen Chen, Xin Yang, Yi Liu, Jia Jia, Yiping Li, Xiaohan Dai, Ousheng Liu
This review summarizes recent advances in piezoelectric materials for anti-infective and regenerative therapies. It highlights antibacterial mechanisms and discusses their anti-infective bioapplications.
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Enzymatic self-assembly of short peptides for cell spheroid formation

J. Mater. Chem. B, 2024, 12,11210-11217
DOI: 10.1039/D4TB01154F, Paper
Open Access
Jiaqi Guo, Weiyi Tan, Bing Xu
Biphenyl-capped phosphopeptides instruct cell aggregation into spheroids, with minimal effective concentrations below 10 μM. Key factors driving morphogenesis include the self-assembly ability and dynamic shapeshifting of the peptide assemblies.
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Acellular dermal matrix hydrogels promote healing of radiation-induced skin injury in a rat model

J. Mater. Chem. B, 2024, 12,11218-11229
DOI: 10.1039/D4TB00941J, Paper
Xin Liu, Tian Guo, Zhifeng Huang, Sen Chen, Li Chen, Chenyang Li, Tian Tian, Yerong Qian, Lifei Yang, Junxi Xiang, Qiufang Liu, Peng Liu
Using a novel rat model of RISI, the research demonstrates that ADM hydrogel effectively reduces wound area and severity, increases epithelial thickness, and accelerates healing compared to controls.
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Improving the sulfite-detection performance of a fluorescent probe via post-synthetic modification with a metal–organic framework

J. Mater. Chem. B, 2024, 12,11251-11258
DOI: 10.1039/D4TB01754D, Paper
Jing-Yi Shi, Bin Wang, Xin-Yue Cui, Xiao-Wei Hu, Hai-Liang Zhu, Yu-Shun Yang
In this work, a post-synthetic modification strategy was attempted to improve the performance of the probe for sulfite detection.
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A simple hydrogen peroxide-activatable Bodipy for tumor imaging and type I/II photodynamic therapy

J. Mater. Chem. B, 2024, 12,11165-11171
DOI: 10.1039/D4TB01650E, Paper
Fangqing Ge, Yujie Sun, Yu Wang, Dan Yu, Zhijia Wang, Fabiao Yu, Bingran Yu, Hongbing Fu
A H2O2-activatable Bodipy with simultaneous type I and type II photosensitization was designed for tumor imaging and therapy.
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Drug-delivery and biological activity in colorectal cancer of a supramolecular porous material assembled from heptameric chromium-copper-adenine entities

J. Mater. Chem. B, 2024, 12,11156-11164
DOI: 10.1039/D4TB01521E, Paper
Sandra Mena-Gutiérrez, Ekain Maiza-Razkin, Jon Pascual-Colino, Marcos J. Araúzo-Bravo, Garikoitz Beobide, Oscar Castillo, Ainara Castellanos-Rubio, Daniela Gerovska, Antonio Luque, Sonia Pérez-Yáñez
Supramolecular metal-organic porous materials as drug delivery systems, modulation of the release kinetics using cholesterol as pore blocking agent and its impact on colorectal cancer cell cultures: cytotoxicity and RNA-seq transcriptomics studies.
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Advances in osteoimmunomodulation of biomaterials after intrabone implantation: focus on surface hydrophilicity

J. Mater. Chem. B, 2024, 12,11089-11104
DOI: 10.1039/D4TB01907E, Review Article
Xinpeng Wei, Linshan Lei, Ling Luo, Ying Zhou, Zheng Zheng, Wenchuan Chen
Hydrophilicity of implantable biomaterials can facilitate osteoimmunomodulation through influencing proteins adsorption, blood clotting, neutrophils activation, macrophages polarization, angiogenesis and osteogenesis to enhance osseointegration.
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Microfluidic synthesis and accurate immobilization of low-density QD-encoded magnetic microbeads for multiplex immunoassay

J. Mater. Chem. B, 2024, 12,11230-11236
DOI: 10.1039/D4TB01585A, Paper
Zhou Sha, Tianyi Ling, Wenqi Yang, Haosu Xie, Chunnan Wang, Shuqing Sun
Accurate immobilization of microbeads in the gap of nickel patterns.
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Effect of supramolecular peptide hydrogel scaffold charge on HepG2 viability and spheroid formation

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01701C, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Yu Xin, Cosimo Ligorio, Marie O’brien, Richard Collins, Siyuan Dong, Aline F. Miller, Alberto Saiani, Julie E. Gough
Understanding how fibre charge in self-assembling peptide hydrogel networks affect HepG2 cell fate and spheroid formation.
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Correction: Blood-clotting model and simulation analysis of polyvinyl alcohol–chitosan composite hemostatic materials

J. Mater. Chem. B, 2024, 12,11265-11266
DOI: 10.1039/D4TB90174F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Yifan Zhao, Junhong Hao, Zexin Chen, Mengmeng Li, Jianxun Ren, Xiaobing Fu
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Nanomaterial-mediated photothermal therapy modulates tumor-associated macrophages: applications in cancer therapy

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01928H, Review Article
Yan Li, Yuhao Si, Heng Yin
Nanomaterials for modulating tumor-associated macrophages in photothermal therapy.
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Development of enzymatically crosslinked natural deep eutectogels: versatile gels for enhanced drug delivery

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01672F, Paper
Liane Meneses, Dimitra Antonia Bagaki, Ana Roda, Alexandre Paiva, Ana Rita C. Duarte
We propose a new injectable eutectogel prepared by enzymatic crosslinking, using NADES, betaine : glycerol (2 : 1), as solvent. The potential of using this material with improved rheological properties as drug delivery system, has also been evaluated.
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Navigating predictions at nanoscale: a comprehensive study of regression models in magnetic nanoparticle synthesis

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB02052A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Lukas Glänzer, Lennart Göpfert, Thomas Schmitz-Rode, Ioana Slabu
The transformative power of support vector regression in optimizing magnetic nanoparticle synthesis intricate relationships between process parameters and particle size, enabling the production of particles with tailored properties.
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Machine Learning-Assisted Pattern Recognition and Imaging of Multiplexed Cancer Cells via Porphyrin-Embedded Dendrimer Array

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01861C, Paper
Jiabao Hu, Weiwei Ni, Mengting Han, Yunzhen Zhan, Fei Li, Hui Huang, Jinsong Han
Early cancer detection plays a vital role in improving the survival rate of cancer patients, underscoring the importance of developing cancer detecting methods. However, it is of great challenge to...
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Nanomaterials and methods for cancer therapy: 2D materials, biomolecules, and molecular dynamics simulations

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01667J, Review Article
Welela M. Kedir, Lunna Li, Yaw Sing Tan, Natasa Bajalovic, Desmond K. Loke
Nanomaterials made from 2D semiconductors and biomolecules are reviewed. Cell-nanoparticle interactions are examined in recent simulations. These nanomaterials and MD simulations reveal novel mechanisms and enable cancer drug delivery and targeting.
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Biomaterials Enhancing Localized Cancer Therapy Activated Anti-Tumor Immunity: A Review

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01995D, Review Article
Jipeng Yao, Zhencun Cui, Feifei Zhang, Haidong Li, Longlong Tian
Localized cancer therapy such as radiotherapy, phototherapy, and chemotherapy are precise cancer treatment strategy, aiming to minimize systemic side effect. However, cancer metastasis remains the primary cause of cancer patients’...
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Enhanced Luminescence and Stability of TFMDSA Nanoparticles via Polymer-Induced aggregation for Bioimaging

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01825G, Paper
Xiang Li, Xue Ren, Yuchao Luo, Haotian Shi, Zhigang Xie, Bin Xu, Wenjing Tian
In recent years, fluorescence imaging occupies a very important position in the life science and biomedical fields. However, achieving nanomaterials for bioimaging with both high fluorescence quantum efficiency and high...
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Polycyclic aromatic polymer nanoparticles show potent infectious particle adsorption capability

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01793E, Paper
Yudai Oishi, Mako Toyoda, Nanami Hano, Chihiro Motozono, Takamasa Ueno, Makoto Takafuji
Nonspecific viral adsorption by polymer nanoparticles is more economical and superior in terms of operating cost and energy efficiency than viral adsorption using virus-specific antibodies and filtration techniques involving size...
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Extracellular matrix mimetic supramolecular hydrogels reinforced with covalent crosslinked mesoporous silica nanoparticles

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB00499J, Paper
Open Access
Aygül Zengin, Shahzad Hafeez, Pamela Habibovic, Matthew Baker, Sabine van Rijt
Here we present a promising strategy to create hybrid, biomimetic supramolecular injectable hydrogels reinforced covalent crosslinked mesoporous silica nanoparticles for tissue engineering applications.
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Mitochondrial membrane potential-independent near-infrared fluorescent probes for viscosity-exclusive imaging

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01785D, Paper
Xiu Pan, Yu Zhao, Jia-Li Wang, Shun Feng, Xiao-Qi Yu, Ming-Yu Wu
A novel mitochondrial targeting mitochondrial membrane potential-independent near-infrared fluorescent probe, ACR-DMA, was developed which can be firmly immobilized in mitochondria for tracking of mitochondrial viscosity changes in vitro and in vivo.
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H2O2-activated mitochondria-targeting photosensitizer for fluorescence imaging-guided combination photodynamic and radiotherapy

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01653J, Paper
Qiufen Tian, Zifan Zhu, Yun Feng, Shirui Zhao, Hui Lin, Wen Zhang, Zhiai Xu
Radiotherapy is a primary modality in cancer treatment but accompanied by severe side effects to healthy tissues and radiation resistance to some extent. To overcome these limitations, we developed a...
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Nanoparticles based image-guided thermal therapy and temperature feedback

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01416B, Review Article
Carlos Jacinto, Wagner Ferreira Silva, Joel Garcia, Gelo P. Zaragosa, Carlo Nonato De Jesus Ilem, Tasso O. Sales, Harrison D. A. Santos, Blessed Isaac C. Conde, Helliomar Pereira Barbosa, Sonia Malik, Surender Kumar Sharma
Nanoparticles have emerged as versatile tools in the realm of thermal therapy, offering precise control and feedback mechanisms for targeted treatments. This review explores the intersection of nanotechnology and thermal...
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Surface-Enhanced Raman Scattering for HSP 70A mRNA Detection in the Live Cells Using Silica Nanoparticles and DNA-Modified Gold Nanoparticles

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01514B, Paper
Ju Eun Cho, Dong-Kwon Lim
Real-time monitoring of mRNA in living cells is crucial for understanding dynamic biological processes. Traditional methods such as northern blotting, PCR, and sequencing require cell lysis and do not allow...
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Illuminating cisplatin-induced ferroptosis in non-small-cell lung cancer with biothiol-activatable fluorescent/photoacoustic bimodal probes

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01656D, Paper
Li Xu, Hongwen Liu, Yi Kong, Lingyun Li, Jia Li, Kang Li, Shuzhi Liang, Bolin Chen
Using activatable NIR fluorescent/PA bimodal probes, we successfully monitored real-time biothiol changes during ferroptosis in NSCLC cells and tumors, revealing enhanced ferroptosis with the combined use of erastin and cisplatin.
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Bioinspired programmable coacervate droplets and self-assembled fibers through pH regulation of monomers

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01550A, Paper
Satyajit Patra, Sushmitha Chandrabhas, Subi J. George
Phase separation or phase transitions pervade the biological domain, where proteins and RNA engage in liquid-liquid phase separation (LLPS), forming liquid-like membraneless organelles. The misregulation or dysfunction of these proteins...
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NIR emissive probe for fluorescence turn-on based dead cell sorting and in vivo viscosity mapping in C. elegans

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01945H, Paper
Goraksha T. Sapkal, Farhan Anjum, Abdul Salam, Bodhidipra Mukherjee, Shilpa Chandra, Purabi Bala, Richa Garg, Shagun Sharma, Kush Kaushik, Chayan Kanti Nandi
An NIR emissive probe plays a pivotal role for in vitro and in vivo dead cell sorting.
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Bigg Boss 10: Mahapurush gets a makeover!

What was garam and thanda on Monday's Bigg Boss episode?









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Bigg Boss 10: Bani gets upset with Salman

Despite Salman Khan counselling Bani to let go of the incident, she felt it apt to defend her gloominess for not becoming captain and gaining immunity. Sweetheart, just three more weeks to go, take a chill pill.




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Yeh Hai Mohabbatein actress Karishma Sharma's HOT photoshoot

Lensman Amit Khanna's fabulous pictures confirm that she's really hot!





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Bigg Boss 10: Manveer is season's first finalist!

There are some victories in the house that make you smile along. And Manveer's victory is one of them, says Divya Nair.