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Curating crisis / Tom Sellar, editor




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A locally funded Puerto Rican parrot (Amazona vittata) genome sequencing project increases avian data and advances young researcher education

A locally funded Puerto Rican parrot (Amazona vittata) genome sequencing project increases avian data and advances young researcher education Oleksyk, Taras K.; Pombert, Jean-Francois; Siu, Daniel; Mazo-Vargas, Anyimilehidi; Ramos, Brian; Guiblet, Wilfried; Afanador, Yashira; Ruiz-Rodriguez, Christina T.; Nickerson, Michael L.; Logue, David M.; Dean, Michael; Figueroa, Luis; Valentin, Ricardo; Martinez-Cruzado, Juan-Carlos Background: Amazona vittata is a critically endangered Puerto Rican endemic bird, the only surviving native parrot species in the United States territory, and the first parrot in the large Neotropical genus Amazona, to be studied on a genomic scale. Findings: In a unique community-based funded project, DNA from an A. vittata female was sequenced using a HiSeq Illumina platform, resulting in a total of ~42.5 billion nucleotide bases. This provided approximately 26.89x average coverage depth at the completion of this funding phase. Filtering followed by assembly resulted in 259,423 contigs (N50=6,983 bp, longest=75,003 bp), which was further scaffolded into 148,255 fragments (N50=19,470, longest=206,462 bp). This provided ~76% coverage of the genome based on an estimated size of 1.58 Gb. The assembled scaffolds allowed basic genomic annotation and comparative analyses with other available avian whole-genome sequences. Conclusions: The current data represents the first genomic information from and work carried out with a unique source of funding. This analysis further provides a means for directed training of young researchers in genetic and bioinformatics analyses and will facilitate progress towards a full assembly and annotation of the Puerto Rican parrot genome. It also adds extensive genomic data to a new branch of the avian tree, making it useful for comparative analyses with other avian species. Ultimately, the knowledge acquired from these data will contribute to an improved understanding of the overall population health of this species and aid in ongoing and future conservation efforts. Sherpa Romeo green journal. Open access article. Creative Commons Attribution 2.0 (CC BY 2.0) applies




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India struggles to revive credit growth

Central bank tries to boost lending but analysts unconvinced plan will work




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India’s twin economic and political crises

The growth slowdown has been dramatic, while politics takes an aggressively illiberal turn




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India’s exporters face crunch as coronavirus pummels economy

Abrupt national lockdown puts 50m jobs at risk in textiles, shoemaking, jewellery and other consumer goods sectors 




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India’s coronavirus crisis hits country’s farmers and food supplies

Lockdown and restrictions on migrant workforce leave crops unpicked as demand collapses




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Real-Time Search in JavaScript

What I meant was scanning the DOM of a page for text equivalents and showing the actual parts of the page, as well as hiding the irrelevant ones. I came up with the technique when I was designing Readerrr’s FAQ page. Take a look at the example:

I have also implemented the solution here on my blog.

How it works

All simple. Let’s take the FAQ page as an example. Here’s a typical markup:

<h1>FAQ</h1>
<div class="faq">
	<input type="search" value="" placeholder="Type some keywords (e.g. giza, babylon, colossus)" />
	<ul>
		<li id="faq-1">
			<h2><a href="#faq-1">Great Pyramid of Giza</a></h2>
			<div>
				<p>The Great Pyramid of Giza <!-- ... --></p>
				<!-- ... -->
			</div>
		</li>
		<li id="faq-2">
			<h2><a href="#faq-2">Hanging Gardens of Babylon</a></h2>
			<div>
				<p>The Hanging Gardens of Babylon <!-- ... --></p>
				<!-- ... -->
			</div>
		</li>
		<!-- ... -->
	</ul>
	<div class="faq__notfound"><p>No matches were found.</p></div>
</div>

I wrote a tiny piece of JavaScript code to handle the interaction and this is how it works:

  1. When the page loads, the script indexes the content of all li’s into browser’s memory.
  2. When a user types text into the search field, the script searches for equivalents among the indexed data and hides the corresponding li’s where no equivalents were found. If nothing found, a message is shown.
  3. The script highlights the text equivalents by replacing phases, for example, babylon becomes <span class="highlight">babylon</span>.

Now, try it yourself:

Demo

Taking it further

Since I chose FAQ page as an example, there are some issues to deal with.

Toggling the answers

It is a good practice to hide the answers by default and show them only when user needs them, that is to say when they press the question:

.faq > ul > li:not( .is-active ) > div
{
	display: none;
}
$( document ).on( 'click', '.faq h2 a', function( e )
{
	e.preventDefault();
	$( this ).parents( 'li' ).toggleClass( 'is-active' );
});

In the CSS part I use child combinator selector > because I don’t want to select and, therefore, to hide the elements of an answer, which may contain lists and div’s.

What if JavaScript is disabled

The user won’t be able to see the answers. Unless you show them by default or develop a JavaScript-less solution. To do this, take a closer look at these fragments of the markup:

  • <li id="faq-1">
  • <a href="#faq-1">

The usage of fragment identifiers enables us to take the advantage of CSS’s pseudo selector :target:

.faq > ul > li:not( :target ) > div
{
	display: none;
}

Furthermore, the real-time search is not possible as well. But you can either provide a sever-side search possibility or hide the search field and so as not to confuse the user:

<html class="no-js">
	<head>
		<!-- remove this if you use Modernizr -->
		<script>(function(e,t,n){var r=e.querySelectorAll("html")[0];r.className=r.className.replace(/(^|s)no-js(s|$)/,"$1$2")})(document,window,0);</script>
	</head>
</html>

I added a class name no-js to <html> element. The <script> part removes that class name. If JavaScript support is disabled in a browser, the class name won’t be removed; therefore:

.no-js .faq input
{
	display: none;
}

The no-js is a very handy technique, you can use it site-wide.

Improving UX

If there is only one list item that matches user’s query, it is a good practice to automatically show the content of that item, without requiring to press the title. To see what I mean, head over the GIF at the beginning of the post.

Hidden keywords

Here on my blog I have a filterable list of blog post titles only. Each post has some related keywords assigned. So, during the search, how do I make an item discoverable even if the title does not consist of a particular keyword? For example, how can I make the entry “Real-Time Search in JavaScript” visible if a user entered “jquery”? Yes, exactly, that is adding keywords and hiding them with CSS:

<li>
	<h2><a href="/real-time-search-in-javascript">Real-Time Search in JavaScript</a></h2>
	<p class="hidden-keywords" aria-hidden="true">jquery filter input html css</p>
</li>
.hidden-keywords
{
	display: none;
}

A simple trick but not always that obvious.


You will find two versions of the code in the source of the demo: without dependencies and jQuery-dependent. These versions are also divided into three groups of code so you can adapt only what your project needs.

Demo




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Learning bio-micro-nanotechnology / Mel I. Mendelson

Hayden Library - TP248.25.N35 M46 2013




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Instrumental community: probe microscopy and the path to nanotechnology / Cyrus C. M. Mody

Barker Library - T174.7.M63 2011




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Advanced in nanoscience and technology: selected, peer reviewed papers from the 10th China International Nanoscience and Technology Symposium, Hangzhou (2011) and the Nano-Products Exposition, sponsored by Chinese Society of Micro-NanoTechnology and IEEE

Hayden Library - T174.7.C459 2011




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Hydrogel micro and nanoparticles / edited by L. Andrew Lyon and Michael Joseph Serpe

Barker Library - TP248.25.N35 H93 2012




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The business of nanotechnology IV: November 25-30, 2012, Boston, Massachusetts, USA / editors, L. Merhari, D. Cruikshank, J. Wang, K. Derbyshire

Hayden Library - T174.7.B88 2012




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Advanced fabrication technologies for micro/nano optics and photonics VII: 3-5 February 2014, San Francisco, California, United States / Georg von Freymann, Winston V. Schoenfeld, Raymond C. Rumpf, editors ; sponsored by SPIE ; cosponsored by Samsung Adva

Online Resource




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Frontiers in micro-nano science and technology: selected, peer reviewed papers from the 12th China International Nanoscience and Technology Symposium, Chengdu (2013) and the Nano-Products Exposition, sponsored by Chinese Society of Micro-Nano Technology,

Hayden Library - T174.7.C456 2013




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Micro-nano technology XV: selected, peer reviewed papers from the 15th Annual Conference and 4th International Conference of the Chinese Society of Micro-Nano Technology (CSMNT 2013), November 3-6, 2013, Tianjin, China / edited by Fei Tang ; [Zheng You, c

Hayden Library - T174.7.C46 2013




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Smart systems integration for micro- and nanotechnologies: honorary volume on the occasion of Thomas Gessner's 60th birthday / Bernd Michel (ed.)

Barker Library - T174.7.S64 2014




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Proceedings of the 14th International Conference of the European Society for Precision Engineering and Nanotechnology: June 2nd-6th, 2014, Dubrovnik, Croatia / editors, R. Leach ; proceedings compilation, N. Charlton, D. Nyman, D. Phillips

Barker Library - T174.7.I59 2014




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Leading edge of micro-nano science and technology: selected peer reviewed papers from the 11th China International Nanoscience and Technology Symposium (CINST 2012), October 21-25, 2012, Kunming, China / edited by Hailin Cong, Bing Yu and Xing Lu

Hayden Library - T174.7.C459 2012




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Micro-and nanotechnologies for sustainable development: selected, peer reviewed papers from the International Conference on Safe and Sustainable Nanotechnology, October 15-17, 2014, Phitsanulok, Thailand / edited by Puangrat Kajitvichyanukul, Suwit Kirvit

Hayden Library - T174.7.M523 2015




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Magnetic nano- and microwires: design, synthesis, properties and applications / edited by Manuel Vázquez

Barker Library - TK7874.85




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CRC concise encyclopedia of nanotechnology / edited by Boris Ildusovich Kharisov, Oxana Vasilievna Kharissova, and Ubaldo Ortiz-Mendez

Online Resource




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Advanced manufacturing, electronics and microsystems / edited by Matthew Laudon, Bart Romanowicz

Barker Library - T174.7.A38 2015




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Democratic experiments: problematizing nanotechnology and democracy in Europe and the United States / Brice Laurent

Dewey Library - T174.7.L379 2017




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Nano meets macro: social perspectives on nanoscale sciences and technologies / editors, Kamilla Lein Kjølberg, Fern Wickson

Online Resource




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Diversity oriented multi-component reaction (DOS–MCR) approach to access natural product analogues: regio- and chemo-selective synthesis of polyheterocyclic scaffolds via one-pot cascade reactions

Org. Biomol. Chem., 2020, 18,3082-3092
DOI: 10.1039/D0OB00368A, Paper
Lakshmanan Palanivel, Vasuki Gnanasambandam
Skeletally diverse and complex polyheterocyclic hybrid scaffolds have been accessed via one-pot three-component reaction by exploiting the build/couple/pair strategy of diversity oriented synthesis.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Progress in recent development of stereoselective synthesis of β2-amino acid derivatives from β-nitroacrylate derivatives

Org. Biomol. Chem., 2020, 18,2991-3006
DOI: 10.1039/D0OB00448K, Review Article
Hao-Wei Zeng, Ping-Yu Wu, Hsyueh-Liang Wu
β2-Amino acids: recent advances in the synthesis of β2-amino acids and their derivatives from various stereoselective transformations of β-nitroacrylates are summarized.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Pseudo-enantiomeric carbohydrate-based N-heterocyclic carbenes as promising chiral ligands for enantiotopic discrimination

Org. Biomol. Chem., 2020, 18,3012-3016
DOI: 10.1039/D0OB00155D, Communication
Alexander S. Henderson, John F. Bower, M. Carmen Galan
The practical synthesis of pseudo-enantiomeric carbohydrate-based NHC–Rh complexes bearing C1 or C3 sterically differentiated positions is reported. We show that steric bulk at either C1 or C3 leads to enantiotopic discrimination in the hydrosilylation of acetophenone.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Ni(II)-Catalyzed vinylic C–H functionalization of 2-acetamido-3-arylacrylates to access isotetronic acids

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00557F, Paper
Biswajit Roy, Eshani Das, Avijit Roy, Dipakranjan Mal
A ligand-free Ni(II)-catalyzed cascade annulation reaction for the synthesis of 4-aryl-substituted isotetronic acids from 2-acetamido-3-arylacrylates via vinylic C–H functionalization is reported.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Discrimination of cellular developmental states focusing on glycan transformation and membrane dynamics by using BODIPY-tagged lactosyl ceramides

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00547A, Paper
Kenta Arai, Atsuko Ohtake, Shusaku Daikoku, Katsuhiko Suzuki, Yukishige Ito, Kazuya Kabayama, Koichi Fukase, Yoshimi Kanie, Osamu Kanie
Different cellular states were discriminated by analysing either the glycan transformation of exogenously introduced fluorescently tagged probe molecules or fluorescence recovery after photobleaching before conversion.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Rhodium-Catalyzed ortho-Acrylation of Aryl Ketone O-Methyl Oximes with Cyclopropenones

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00064G, Communication
Yafeng Liu, Yuan Tian, Kexin Su, Xin Guo, Baohua Chen
An efficient Rh-catalyzed ortho-acrylation reaction for the synthesis of chalcones from O-methyl ketoximes and cyclopropenones via C–H bond activation has been described. This cross-coupling reaction exhibits high functional group tolerance...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Blue emissive dimethylmethylene-bridged triphenylamine derivatives appending cross-linkable groups

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00622J, Paper
Kangyu Zhou, Hongfei Pan, Yongjie Zhang, Houchen Wang, Xiaofei Dong, Xiangkui Ren, Xianggao Li, Shirong Wang, Zhijian Chen
Blue-emissive and cross-linkable dimethylmethylene-bridged triphenylamine derivatives were synthesized and their optical and electrochemical properties were investigated.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Direct recognition and sensitive detection of circular RNA with ligation-based PCR

Org. Biomol. Chem., 2020, 18,3269-3273
DOI: 10.1039/D0OB00625D, Communication
Pengbo Zhang, Na Guo, Kejian Gao, Fengxia Su, Fangfang Wang, Zhengping Li
A sensitive and specific method for circRNA detection is developed through the direct ligation of two ingeniously designed DNA probes.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Correction: Synthetic-biology-based discovery of a fungal macrolide from Macrophomina phaseolina

Org. Biomol. Chem., 2020, 18,3392-3392
DOI: 10.1039/D0OB90051F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Yohei Morishita, Terutaka Sonohara, Tohru Taniguchi, Kiyohiro Adachi, Makoto Fujita, Teigo Asai
The content of this RSS Feed (c) The Royal Society of Chemistry




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Synthesis of gem-difluoroalkenes via nickel-catalyzed allylic defluorinative reductive cross-coupling of trifluoromethyl alkenes with epoxides

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00535E, Communication
Xiao-Yu Lu, Run-Chuang Jiang, Jia-Mei Li, Chuang-Chuang Liu, Qing-Qing Wang, Hai-Pin Zhou
A nickel-catalyzed defluorinative reductive cross-coupling of trifluoromethyl alkenes with epoxides has been developed.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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TN woman seeks Rs 1 cr compensation from AIDS society

A housewife has moved the Madras High Court seeking Rs 1 crore as compensation and a public apology from the Tamil Nadu AIDS Control Society.




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Five-year-old survives 40-feet fall with minor scratches

A five-year old boy here survived a 40-feet fall from a multi-storeyed building with minor scratches.




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Australia-India cricket rivalry has even bettered Ashes: John Harnden

CEO of the ICC World Cup 2015 John Harnden spoke with Amin Ali about ensuring excitement in cricket's mega-tournament, clamping down on racism, managing 'minnows' matches — and how Australia is sizing up India as a rival for the trophy.




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Hate crime: Two Sikhs attacked in US, one dead

Two elderly Sikhs were shot at by unidentified assailants in Sacramento in US, leaving one dead and the other in critical condition, triggering panic in the neighbourhood having a sizeable Sikh population.




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Delhi: Liquor hunt shifts online, site crashes

The Delhi government's initiative to reduce crowding outside liquor stores by issuing e-tokens - one could book a time slot to buy the tipple without getting into long queues - failed to work as the excise department website crashed due to heavy rush late Thursday.




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Why Ayushmann is not interested in Rs 200 crores

'I can do slice-of-life kind of films anytime; But playing a cop is different. It's difficult to maintain that intensity on screen. That's where the real acting comes in place.'




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'I know how crazy Kangana is with her acting'

'If you listen to the title track of Judgementall Hai Kya, you will find some crazy things happening in it -- from crazy laughter to as if someone is inside your mind.'






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'Akshay Kumar made me cry!'

'Akshay Kumar takes care of each and every person on the sets. He does not waste a second of a producer's time and money. It's no wonder that he is doing films back-to-back because people love him so much.'







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'I can't wait for this crisis to end'

'I was almost forgotten after Filmistaan as nothing substantial, or should I say, successful in terms of box office, came my way.'




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'People want to see me on screen'

'It is very difficult for anybody to say no to the fame and fancies that come along.''But I was courageous and had the strength to say no.'




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'I want to run out and scream'

'I meet him recently.''He was his usual cheerful, boisterous, self.''You didn't even get an iota of feeling about what he had gone through or may be going through internally.'