Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02653E, Review Article

Li Li, Jian-Ge Zeng, Ning-Ning Zhang, Yu Yang-Tao, Shu-Hao Li, Yang Hua
The multifunctional stimuli-responsive photochromic materials significantly expand their application fields, including molecular switching, information storage and encryption, detection and sensing, etc. 1,4,5,8-naphthalenediimides (NDIs) have been widely used for the construction...
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Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02016B, Research Article

Xiaoyu Jiang, Boran Tao, Hongda Li
A multistage construction of the Gd-doped g-C₃N₄/Mo₁₅S₁₉ catalyst, with Gd³⁺ as redox centers and Mo₁₅S₁₉ as N₂ activation sites, synergistically enhances its photocatalytic NRR performance.
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Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02260B, Research Article

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Xiaowei Zhang, Dashuai Sun, Pengcheng Luo, Luhui Zhou, Zheng Lu, Jia Liu, Congcong Fan, Xinyu Ye, Hongpeng You
Novel high-efficiency near-infrared phosphors with tunable luminescence via Cr³⁺–Yb³⁺/Nd³⁺ energy transfer for non-destructive analysis.
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Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02350A, Research Article

Zongyi Wang, Jiuli Chang, Zhiyong Gao
Nitrate–methanol co-electrolysis by the pairwise cathodic NO₃RR and anodic MOR is a viable way to coproduce ammonia (NH₃) and formate via gentle, sustainable and energy-saving “E-refining” and “E-reforming” means.
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Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02280G, Research Article

Qixian Ren, Wangfei Che, Mengmeng Chen, Chen Cui, Yabo Wu, Zhi Su
Thioantimonates containing high oxidation state Sb5+ have proven to exhibit excellent performance in the design of new materials such as infrared optics crystals and lithium-ion batteries. However, as described by...
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Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI02340D, Research Article

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Ruyi Bi, Jilu Zhao, Mei Yang, Jiangyan Wang, Ranbo Yu, Dan Wang
A multifunctional separator modified with a multi-shelled CoS₂ structure is developed to simultaneously inhibit the shuttle effect and effectively catalyze the redox reactions.
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Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI02296C, Research Article

Katarzyna Zakret-Drozdowska, Bożena Szermer-Olearnik, Waldemar Goldeman, Michalina Gos, Dawid Drozdowski, Anna Gągor, Tomasz M. Goszczyński
Over the past decade, considerable scientific attention has been given to adapting cobalt bis(dicarbollides) as innovative agents with various biomedical applications. Although the studied compounds show great potential in this...
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Lab Chip, 2024, 24,1965-1976
DOI: 10.1039/D3LC01007D, Paper

Wei-Jen Soong, Chih-Hung Wang, Chihchen Chen, Gwo-Bin Lee
We devised an innovative method for automated sorting of extracellular vesicles (EVs) employing optically-induced dielectrophoresis on an integrated microfluidic chip. EVs of three distinct size categories could be isolated in 1 h at a purity of 86%.
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Lab Chip, 2024, 24,1987-1995
DOI: 10.1039/D4LC00096J, Paper

Bin Guo, Chong Hu, Zeping Yang, Chu Tang, Chuanxian Zhang, Fu Wang
In this study, we employed Cas12a protein and enzyme-assisted cycle amplification technology with a test strip to establish a precise platform for the detection of UDG enzyme.
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Lab Chip, 2024, 24,1996-2004
DOI: 10.1039/D3LC01094E, Paper

Zhaoxian Chen, Wei Wang, Hao Tian, Wenrou Yu, Yu Niu, Xueli Zheng, Shihong Liu, Li Wang, Yingzhou Huang
A wearable intelligent SERS platform enables the sensitive detection of UA (0.1 μM) in sweat for AI diagnosis of gout.
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Lab Chip, 2024, 24,2058-2068
DOI: 10.1039/D3LC00942D, Paper

Xiaoming Chen, Mo Shen, Shun Liu, Chungang Wu, Liangliang Sun, Zhipeng Song, Jishun Shi, Yulong Yuan, Yong Zhao
We develop a novel microfluidic impedance cytometer for analysis of marine microalgae by inserting ground flat-end cylindrical electrodes into microchannels.
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Lab Chip, 2024, 24,1887-1902
DOI: 10.1039/D3LC00507K, Paper

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Chu-Chun Liang, Po-Yen Chen, Nien-Che Liu, I-Chi Lee
A 3D neural spheroid-based system with an interstitial level of flow for simulating the brain microenvironment toward a dynamic amyloid-β induced neuronal toxic model was established. A real-time impedance recording was used to monitor the neural network formation and disconnection.
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Lab Chip, 2024, 24,2080-2093
DOI: 10.1039/D3LC00838J, Paper

Open Access

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Katharina Schlünder, Madalena Cipriano, Aline Zbinden, Stefanie Fuchs, Torsten Mayr, Katja Schenke-Layland, Peter Loskill
Pancreatic in vitro models are crucial for research on diseases such as diabetes mellitus. A novel thermoplastic organ-on-chip with integrated real-time read-outs models the complex microphysiological structure and function of the endocrine pancreas.
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Lab Chip, 2024, 24,2025-2038
DOI: 10.1039/D3LC01044A, Paper

Qiyue Luan, Ines Pulido, Angelique Isagirre, Julian Carretero, Jian Zhou, Takeshi Shimamura, Ian Papautsky
Agarose microwell platform for modeling lung carcinoma using patient-derived tissues to decipher cancer associated fibroblast-induced drug resistance.
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Lab Chip, 2024, 24,1867-1874
DOI: 10.1039/D3LC00796K, Perspective

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Umut A. Gurkan, David K. Wood, Dorn Carranza, Luke H. Herbertson, Scott L. Diamond, E. Du, Suvajyoti Guha, Jorge Di Paola, Patrick C. Hines, Ian Papautsky, Sergey S. Shevkoplyas, Nathan J. Sniadecki, Vamsee K. Pamula, Prithu Sundd, Asif Rizwan, Pankaj Qasba, Wilbur A. Lam
In this perspective article, we present the state of the microfluidic field regarding current limitations and propose future directions and new approaches for the field to advance lab-on-a-chip technologies closer to translation and clinical use.
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D3LC00891F, Paper

Yu-Hsiang Hsu, Wen-Chih Yang, Yi-Ting Chen, Che-Yu Lin, Chiou-Fong Yang, Wei-Wen Liu, Subhashree Shivani, Pai-Chi Li
The DC-MPS device uses a velocity V-clamp to create a partition with a steep concentration gradient for simultaneously developing vasculogenic vessels and a tumor. It enables vessel–tumor interaction to develop a tumor model with angiogenic vessels.
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Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D4LC00118D, Paper

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Jiaheng Li, Lok Ting CHU, Hogi Hartanto, Guihuan Guo, Lu LIU, Jianpeng WU, Minghui Wu, Chenyu Cui, Gaobo Wang, Wengang LIU, Hoi Kwan Kwong, Siying WU, Ting-Hsuan Chen
Mucosal antibodies at the upper respiratory tract are the earliest and most critical responders to prevent respiratory infections, providing an indication to rapidly evaluate immune protection. Here, we report a...
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00131A, Paper

Fahima Akther, Hedieh Fallahi, Jun Zhang, Nam-Trung Nguyen, Hang Thu Ta
An atherothrombosis-on-chip model to evaluate thrombosis risk and patient-specific treatment strategy.
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D3LC01061A, Paper

Open Access

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Felix Reichel, Ruchi Goswami, Salvatore Girardo, Jochen Guck
We use hyperbolic microchannels to create a flow field with linearly increasing velocity, leading to a constant tensile stress to probe the viscoelastic properties of cells. We verify our approach on oil droplets and polyacrylamide beads.
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Lab Chip, 2024, 24,2176-2192
DOI: 10.1039/D3LC00912B, Paper

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Priscilla Delgado, C. Alessandra Luna, Anjana Dissanayaka, Oluwamayokun Oshinowo, Jesse J. Waggoner, Sara Schley, Todd Fernandez, David R. Myers
This activity enables students to construct geometrically complex microfluidics at their desk with no specialized equipment. It can be easily transported, and helped students significantly improve their understanding of miniaturization science.
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Lab Chip, 2024, 24,2253-2261
DOI: 10.1039/D3LC01053H, Paper

Ziran Ye, Ping Lu, Yiben Chen, Zhixian Xu, Haixia Huang, Mingjia Zhi, Zi Ang Chen, Bo Yan
We present an efficient approach for the consecutive synthesis of Au–TiO₂ nanocomposites with controlled morphologies in a microfluidic chip.
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Lab Chip, 2024, 24,2262-2271
DOI: 10.1039/D4LC00055B, Paper

Kawin Khachornsakkul, Ruben Del-Rio-Ruiz, Lita Chheang, Wenxin Zeng, Sameer Sonkusale
A carbon dots and dopamine-imprinted polymer was immobilized onto a distance-based paper channel for simultaneous detection of three cytokine biomarkers without requiring expensive reagents and instruments.
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Lab Chip, 2024, 24,2202-2207
DOI: 10.1039/D4LC00014E, Paper

Matthew S. Viglione, Aubrianna Saxton, Dawson Downs, Adam T. Woolley, Kenneth A. Christensen, Pam M. Van Ry, Gregory P. Nordin
A new 3D printing method allows for fabrication of porous membranes with 7 μm pores. A device mimicking an organ-on-a-chip design is fabricated and seeded with living cells, demonstrating potential for diverse biological and mechanical applications.
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Lab Chip, 2024, 24,2208-2223
DOI: 10.1039/D3LC01055D, Paper

Open Access

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Jungseub Lee, Sangmin Jung, Hye Kyoung Hong, Hyeonsu Jo, Stephen Rhee, Ye-Lin Jeong, Jihoon Ko, Yong Beom Cho, Noo Li Jeon
VT-MAP, a novel in vitro platform, offers better physiological reflection through the vascularized organoid. This advancement supports drug assessment with deeper insights into cancer biology through correlation between morphology and drug effects.
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00087K, Paper

Mohammad Mahdi Mardanpour, Ayyappasamy Sudalaiyadum Perumal, Zahra Mahmoodi, Karine Baassiri, Gala Montiel-Rubies, Kenneth M. LeDez, Dan V. Nicolau
This study conducted in vitro experimentation using microvascular tissue-like structures to examine the dynamics of interfacial forces leading to gas bubble cessation, with the objective of providing a medical guideline for preventing gas embolism.
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00012A, Paper

Anna L. Butterworth, Matin Golozar, Zachary Estlack, Jeremy McCauley, Richard A. Mathies, Jungkyu Kim
This work presents the design, fabrication, and automation of our space flight-format microfabricated sample processing and capillary electrophoresis analysis instrument.
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D3LC01052J, Paper

Wenxin Wang, Yiyuan Liu, Zhikai Yao, Dengbo Chen, Yue Tang, Jingwei Cui, Jiangjiang Zhang, Hong Liu, Zikai Hao
A depression-on-gut-chip (DoGC) is prepared and enables extended co-culture of aerobic human intestinal epithelial cells and anaerobic gut microbiota, and allows direct study of interactions between human gut microbiota and depression.
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Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D4LC00105B, Critical Review

Shanqing Huang, Weixiong Shi, Shiyu Li, Qian Fan, Chaoyong Yang, Jiao Cao, Lingling Wu
Cells are the fundamental building blocks of living systems, exhibiting significant heterogeneity. The transcriptome connects the cellular genotype and phenotype, and profiling single-cell transcriptome is critical for uncovering distinct cell...
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00163J, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Yujia Li, Yingqi Kong, Yubing Hu, Yixuan Li, Rica Asrosa, Wenyu Zhang, Buddha Deka Boruah, Ali K. Yetisen, Andrew Davenport, Tung-Chun Lee, Bing Li
A safe, accurate, and reliable sensing platform for urinary biomarkers analysis of urinary biomarkers is clinically important for the early detection and monitoring of the progression of chronic kidney disease (CKD), as it has become one of the world's most prevalent non-communicable diseases.
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00016A, Paper

Ethan J. Lockhart, Lisa F. Horowitz, Adán Rodríguez, Songli Zhu, Tran Nguyen, Mehdi Mehrabi, Taranjit S. Gujral, Albert Folch
A microfluidic platform was developed that hydrodynamically traps microdissected cuboids for selective drug treatments and isolates conditions with thermoplastic valves.
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React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00419A, Communication

Kareesa J. Kron, Shaama Mallikarjun Sharada
In the photoredox catalytic cycle of CO₂ reduction with organic chromophores, this work observes a linear relationship between the energies of (desirable) electron transfer to CO₂ and (undesirable) carboxylation of the chromophore radical anion.
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React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00237G, Communication

Linjiang Zhu, Yuxin Wang, Linyan Pan, Enyong Lin, Jiayan Wang, Xiaolong Chen
A simple and cost-effective one-pot three-enzyme cascade reaction for high-yield production of L-5-methyltetrahydrofolate, including dihydrofolate reductase, tetrahydrofolate-dependent methyltransferase and alcohol dehydrogenase.
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React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00346B, Paper

Qifeng Yang, Liping Liang, Ning Xu, Yang Li, Zhihui Wang, Dadong Shen, Yiming Mo
A cerium-mediated electrooxidation method was developed for synthesizing vitamin K₃ in a green and efficient manner. A systematic technoeconomic analysis was provided to understand its potential for practical implementation.
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React. Chem. Eng., 2024, 9,2882-2891
DOI: 10.1039/D4RE00175C, Paper

Aravind Senthil Vel, Daniel Cortés-Borda, François-Xavier Felpin
This paper presents a chemist's guide for selecting multi-objective optimization algorithms for reaction optimization.
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React. Chem. Eng., 2024, 9,2868-2881
DOI: 10.1039/D4RE00168K, Paper

Open Access

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Tim Delrieux, Shweta Sharma, Florian Maurer, Paolo Dolcet, Maximilian Lausch, Anna Zimina, Camilo Cárdenas, Patrick Lott, Maria Casapu, Thomas Lennon Sheppard, Jan-Dierk Grunwaldt
This work presents a fast and non-invasive photo-based channel analysis approach, which helps to screen and understand the effects of different coating parameters on the activity of noble metal-based oxidation catalyst coated on a ceramic cordierite.
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React. Chem. Eng., 2024, 9,2925-2937
DOI: 10.1039/D4RE00271G, Paper

Nicolás Salas, Justin López, Carlos A. Arango
Effect of permutations σ_12,0 and σ₂₁ on graph G₂.
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React. Chem. Eng., 2024, 9,2975-2983
DOI: 10.1039/D4RE00301B, Paper

Yoshihiro Takebayashi, Kiwamu Sue, Sho Kataoka
An automated flow reactor with a rapid inline monitoring using a compact near-infrared spectrometer and a flow rate ramp control enabled high-density kinetic data acquisition.
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React. Chem. Eng., 2024, 9,2915-2924
DOI: 10.1039/D3RE00417A, Paper

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Pinaki Ranadive, Faiz Khan, Jessica O. Winter, Nicholas Brunelli
Sequential jet mixing reactors enable core@shell nanomaterial synthesis.
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React. Chem. Eng., 2024, 9,2963-2974
DOI: 10.1039/D4RE00241E, Paper

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Esai Daniel Lopez, Patricia Zhang Musacchio, Andrew R. Teixeira
Wirelessly powering μLEDs within packed bed reactors enables scalable, continuous, green chemical manufacturing by overcoming classical light penetration limits.
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React. Chem. Eng., 2024, 9,2994-3002
DOI: 10.1039/D4RE00265B, Paper

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Adrian Ioan Dudu, Csaba Paizs, Monica Ioana Toşa
In this study, the synthesis of aroma esters by the direct esterfication of carboxylic acids with aromatic alcohols mediated by lipase B from Candida antarctica encapsulated in a sol–gel matrix in a solvent-free system is presented.
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React. Chem. Eng., 2024, 9,3003-3015
DOI: 10.1039/D4RE00202D, Paper

Riska Rachmantyo, Afif Akmal Afkauni, Ricky Reinaldo, Lei Zhang, Arramel Arramel, Muhammad Danang Birowosuto, Arie Wibowo, Hermawan Judawisastra
This study shows that a narrower band gap TiO₂, namely black TiO₂, can be prepared using NaBH₄ as a reducing material and microwave heating, which is a faster, greener, and simpler method than the existing method using furnace heating.
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React. Chem. Eng., 2024, 9,3038-3046
DOI: 10.1039/D4RE00235K, Paper

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Maria Schlüter, Ryota Enomoto, Shin Makino, Lisa Weihs, Cyra Lina Stamm, Kerstin Wohlgemuth, Christoph Held
Glycolysis is the most promising chemical recycling method to depolymerize poly(ethylene terephthalate) (PET) with ethylene glycol (EG) into the monomer bis(2-hydroxyethyl) terephthalate (BHET).
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React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00401A, Paper

Lucas Ramos, Giovani Maltempi-Mendes, Adriano Francisco Siqueira, Diovana Aparecida dos Santos Napoleão, Anuj Kumar Chandel
Lignin conversion through an advanced oxidative process.
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React. Chem. Eng., 2024, Accepted Manuscript
DOI: 10.1039/D4RE00384E, Minireview

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Hongqi Wang, Raveendran N. Shiju
The catalytic aromatization of n-alkanes is an important process in the chemical industry, especially for the production of valued-added aromatics from the abundant and unreactive small alkanes. This mini review...
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React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00300D, Paper

Q. Shen, A. Pikalev, F. J. J. Peeters, J. Gans, M. C. M. van de Sanden
A two-temperature model with a vibrational temperature different from the gas temperature is presented for the decomposition of CO₂.
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React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00406J, Paper

Judith Cabello-Romero, Román Torres-Lubián, Javier Francisco Enríquez-Medrano, Adrián Ochoa-Terán, Jesús Jara-Cortés, Iván Zapata-González
Transesterification of 2-(diethylamino)ethyl methacrylate (DEAEMA) with methanol leads to the formation of methyl methacrylate (MMA) and amino alcohol. This reaction significantly affects DEAEMA polymerization giving rise to poly(DEAEMA-co-MMA).
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React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00379A, Paper

Ning Ma, Liu Yang, Zhenchang Fang, Kaijia Jiang, Xinling Li, Zhen Huang
This study synthesized a novel homogeneous non-aqueous absorbent and analyzed hydrogen bonds and viscosities, which were rarely studied before.
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React. Chem. Eng., 2024, Advance Article
DOI: 10.1039/D4RE00397G, Paper

Xin Liu, Yuxin Yan, Zhenyu Liu, Qingya Liu
A novel synthesis of xanthenes and ethylphenols by the reaction of phenol with CaC₂ without catalysts and solvents.
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Soft Matter, 2024, 20,2969-2977
DOI: 10.1039/D4SM00204K, Paper

Rounak Bhattacharyya, Bhaskar Sen Gupta
Phase separation of segregating fluid mixtures in the presence of quenched disorder.
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Soft Matter, 2024, 20,2900-2914
DOI: 10.1039/D3SM01616A, Paper

Lucas Myers, Carter Swift, Jonas Rønning, Luiza Angheluta, Jorge Viñals
The structure of isolated disclinations and disclination dipoles in anisotropically elastic nematic liquid crystals is explored via a singular potential computational model.
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