be Patient's rights in research - moving beyond participation By feeds.bmj.com Published On :: Thu, 25 Jul 2019 14:54:57 +0000 At EBM live recently, we ran a workshop with researchers, patients and clinicians to talk about patient rights in research - should patients be setting the full research agenda? Should they be full participants and authors? Helen Macdonald, BMJ’s UK research editor and co-host of our talk evidence podcast sat down to Paul Wicks, researcher and... Full Article
be A new way to look at behaviour change in UK GPs By feeds.bmj.com Published On :: Tue, 08 Oct 2019 14:52:42 +0000 In quality improvement, measurement is seen as a key driver of change - how well do you know you’re doing, if you can’t actually measure it. So, when something changes in the NHS (say a new guideline) how can you tell how quickly that’s filtering down to the front line. Ben goldacre, from the Nuffield Department of Primary Care Health Sciences... Full Article
be Talk Evidence - aggravating acronyms, a time to prescribe, and screening (again) By feeds.bmj.com Published On :: Mon, 11 Nov 2019 11:51:44 +0000 Talk Evidence is back, with your monthly take on the world of EBM with Duncan Jarvies and GPs Carl Heneghan (also director for the Centre of Evidence Based Medicine at the University of Oxford) and Helen Macdonald (also The BMJ's UK research Editor). This month Helen talks about the messy business of colon cancer screening - which modality is... Full Article
be Behind the campaign promises - GP numbers, and appointment slots By feeds.bmj.com Published On :: Fri, 15 Nov 2019 16:59:59 +0000 A UK general election has been called - polling day is on the 12th of December, and from now until then we’re going to be bringing you a weekly election-themed podcast. We want to help you make sense of the promises and pledges, claims and counter-claims, that are being made around healthcare and the NHS out on the campaign trail. This week has... Full Article
be Behind the campaign promises - Health and social care spending By feeds.bmj.com Published On :: Fri, 22 Nov 2019 16:21:30 +0000 A UK general election has been called - polling day is on the 12th of December, and from now until then we’re going to be bringing you a weekly election-themed podcast. We want to help you make sense of the promises and pledges, claims and counter-claims, that are being made around healthcare and the NHS out on the campaign trail. This week... Full Article
be Behind the campaign promises - Health beyond the NHS By feeds.bmj.com Published On :: Sat, 30 Nov 2019 09:10:48 +0000 A UK general election has been called - polling day is on the 12th of December, and from now until then we’re going to be bringing you a weekly election-themed podcast. We want to help you make sense of the promises and pledges, claims and counter-claims, that are being made around healthcare and the NHS out on the campaign trail. This week... Full Article
be Behind the campaign promises - what the NHS means for the election By feeds.bmj.com Published On :: Thu, 05 Dec 2019 19:09:30 +0000 UK general election has been called - polling day is on the 12th of December, and from now until then we’re going to be bringing you a weekly election-themed podcast. We want to help you make sense of the promises and pledges, claims and counter-claims, that are being made around healthcare and the NHS out on the campaign trail. This week we're... Full Article
be Behind the campaign promises - Doctors in parliament By feeds.bmj.com Published On :: Mon, 09 Dec 2019 18:52:26 +0000 The UK general election is happening this week, and you’ve probably made your mind up which MP you’re voting for already - and maybe the NHS has influenced that decision. This year has seen an increase in the number of doctors running for parliament, and in this podcast we find out what motivates doctors to step away from clinical practice, and... Full Article
be Michael West - GMC Report On Wellbeing By feeds.bmj.com Published On :: Fri, 10 Jan 2020 15:02:33 +0000 Michael West is professor of organisational psychology, at Lancaster University, and co-author of a new GMC report into the wellbeing of NHS staff. The review he led together with the clinical psychiatrist Denise Coia, focused on primary interventions related to workplace factors and the systems that doctors work in, rather than secondary... Full Article
be Prevalence and treatment of precocious puberty By feeds.bmj.com Published On :: Tue, 28 Jan 2020 17:19:40 +0000 Precocious puberty, that is puberty that starts before age 8 in girls and 9 in boys seems to be on the rise, but whether that’s because of an increase in incidence, or greater attention is unknown - what we do know that precocious puberty in girls is commonly idiopathic, while in boys is a red flag for pathology. But either way ther first point of... Full Article
be Big Tan - Is the sunbed industry targeting research? By feeds.bmj.com Published On :: Mon, 10 Feb 2020 17:42:30 +0000 In 2012, Eleni Linos, professor of dermatology at Stanford university, published a systematic review and meta-analysis of the link between non-melanoma cancer and sun-beds. That bit of pretty standard research, and a particular rapid response to it, has kicked of years of work - and in this podcast I talk to Eleni and her colleagues Stanton... Full Article
be Cycling - Does the health benefit outweigh the accident risk (in the UK) By feeds.bmj.com Published On :: Thu, 12 Mar 2020 16:22:11 +0000 We all know we should be doing more exercise, and one way to do that is by active commuting - journeying to work on foot or by bike. One thing preventing people from taking up cycling is the fear of being involved in road traffic accidents, and that the risk isn't worth the benefit of the extra exercise. It’s even more confusing when air... Full Article
be Wellbeing - Some advice on working in PPE By feeds.bmj.com Published On :: Wed, 08 Apr 2020 17:38:56 +0000 Wellbeing might not seem the obvious place to talk about PPE - but lack of appropriate PPE is causing healthcare staff a great deal of stress now. Mary Brindle is a pediatric surgeon and the director of The EQuIS (Efficiency Quality Innovation and Safety) Research platform at Alberta Children’s hospital. In this podcast she reflects on the use... Full Article
be Wellbeing - some advice for telehealth in secondary care By feeds.bmj.com Published On :: Thu, 16 Apr 2020 18:30:00 +0000 We’ve published info on Telehealth in primary care - and have been overwhelmed by the response from GPs who are finding it useful. But it’s not only primary care that is dramatically shifting to remote care - routine hospital care is moving online too, so we’ve asked Rowena McCash - GP and out of hours triage trainer joins us to give some tips... Full Article
be Wellbeing – advice from a military medic to frontline clinicians By feeds.bmj.com Published On :: Wed, 22 Apr 2020 11:53:26 +0000 There is no doubt that anxiety levels that clinicians are feeling during this pandemic are high. One military medic believes the current situation is comparable to his experience when posted during British campaigns in Afghanistan and Iraq. Cormac Doyle offers advice on how to deal with high-stress conditions, both in a work and at home, as... Full Article
be Wellbeing – how one junior doctor found a way to support frontline staff By feeds.bmj.com Published On :: Wed, 29 Apr 2020 17:17:18 +0000 How can we help frontline clinicians? Sometimes medics may feel uneasy or even guilty and that they could be doing more. That was what a junior doctor in Abergavenny in Wales felt and she did something about it. In this podcast, we speak to Josie Cheetham about how she started her initiative to provide support boxes in hospitals for her... Full Article
be Wellbeing – coping with Covid fatigue By feeds.bmj.com Published On :: Fri, 08 May 2020 10:00:46 +0000 We are more than six weeks into the lockdown and if you were to gauge the mood of the nation, it would be one of fatigue. It started as an all-hands-on-deck emergency situation, but it now transpires that the current work situation for healthcare professionals is not going to change any time soon. This is a marathon rather than a sprint. So how... Full Article
be Glucose-Induced Reactive Oxygen Species Cause Apoptosis of Podocytes and Podocyte Depletion at the Onset of Diabetic Nephropathy By diabetes.diabetesjournals.org Published On :: 2006-01-01 Katalin SusztakJan 1, 2006; 55:225-233Complications Full Article
be C-Reactive Protein Is an Independent Predictor of Risk for the Development of Diabetes in the West of Scotland Coronary Prevention Study By diabetes.diabetesjournals.org Published On :: 2002-05-01 Dilys J. FreemanMay 1, 2002; 51:1596-1600Complications Full Article
be The Effect of Thiazolidinediones on Plasma Adiponectin Levels in Normal, Obese, and Type 2 Diabetic Subjects By diabetes.diabetesjournals.org Published On :: 2002-10-01 Joseph G. YuOct 1, 2002; 51:2968-2974Obesity Studies Full Article
be Diabetes and Cardiovascular Disease: The "Common Soil" Hypothesis By diabetes.diabetesjournals.org Published On :: 1995-04-01 Michael P SternApr 1, 1995; 44:369-374Perspectives in Diabetes Full Article
be Morbidity and Mortality in Diabetics In the Framingham Population: Sixteen Year Follow-up Study By diabetes.diabetesjournals.org Published On :: 1974-02-01 Mariano J GarciaFeb 1, 1974; 23:105-111Original Contribution Full Article
be Endothelial Progenitor Cell Dysfunction: A Novel Concept in the Pathogenesis of Vascular Complications of Type 1 Diabetes By diabetes.diabetesjournals.org Published On :: 2004-01-01 Cindy J.M. LoomansJan 1, 2004; 53:195-199Complications Full Article
be Thiazolidinediones in the Treatment of Insulin Resistance and Type II Diabetes By diabetes.diabetesjournals.org Published On :: 1996-12-01 Alan R SaltielDec 1, 1996; 45:1661-1669Perspectives in Diabetes Full Article
be Relation Between Antioxidant Enzyme Gene Expression and Antioxidative Defense Status of Insulin-Producing Cells By diabetes.diabetesjournals.org Published On :: 1997-11-01 Markus TiedgeNov 1, 1997; 46:1733-1742Original Article Full Article
be Are the {beta}-Cell Signaling Molecules Malonyl-CoA and Cystolic Long-Chain Acyl-CoA Implicated in Multiple Tissue Defects of Obesity and NIDDM? By diabetes.diabetesjournals.org Published On :: 1996-03-01 Marc PrentkiMar 1, 1996; 45:273-283Original Article Full Article
be Cell-Permeable Peptide Inhibitors of JNK: Novel Blockers of {beta}-Cell Death By diabetes.diabetesjournals.org Published On :: 2001-01-01 Christophe BonnyJan 1, 2001; 50:77-82Islet Studies Full Article
be Inflammatory Cytokines and the Risk to Develop Type 2 Diabetes: Results of the Prospective Population-Based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study By diabetes.diabetesjournals.org Published On :: 2003-03-01 Joachim SprangerMar 1, 2003; 52:812-817Pathophysiology Full Article
be Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents By diabetes.diabetesjournals.org Published On :: 1999-08-01 G PerseghinAug 1, 1999; 48:1600-1606Articles Full Article
be NCEP-Defined Metabolic Syndrome, Diabetes, and Prevalence of Coronary Heart Disease Among NHANES III Participants Age 50 Years and Older By diabetes.diabetesjournals.org Published On :: 2003-05-01 Charles M. AlexanderMay 1, 2003; 52:1210-1214Complications Full Article
be Mechanisms of Pancreatic {beta}-Cell Death in Type 1 and Type 2 Diabetes: Many Differences, Few Similarities By diabetes.diabetesjournals.org Published On :: 2005-12-01 Miriam CnopDec 1, 2005; 54:S97-S107Section III: Inflammation and beta-Cell Death Full Article
be Tumor Necrosis Factor {alpha}: A Key Component of the Obesity-Diabetes Link By diabetes.diabetesjournals.org Published On :: 1994-11-01 Gökhan S HotamisligilNov 1, 1994; 43:1271-1278Perspectives in Diabetes Full Article
be Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships By diabetes.diabetesjournals.org Published On :: 2000-12-01 D DabeleaDec 1, 2000; 49:2208-2211Articles Full Article
be Insulin Action, Diabetogenes, and the Cause of Type II Diabetes By diabetes.diabetesjournals.org Published On :: 1994-08-01 C. Ronald KahnAug 1, 1994; 43:1066-1085Banting Lecture Full Article
be From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus By diabetes.diabetesjournals.org Published On :: 2009-04-01 Ralph A. DeFronzoApr 1, 2009; 58:773-795Banting Lecture Full Article
be Protein kinase C activation and the development of diabetic complications By diabetes.diabetesjournals.org Published On :: 1998-06-01 D KoyaJun 1, 1998; 47:859-866Articles Full Article
be Lipotoxicity in the Pathogenesis of Obesity-Dependent NIDDM: Genetic and Clinical Implications By diabetes.diabetesjournals.org Published On :: 1995-08-01 Roger H UngerAug 1, 1995; 44:863-870Perspectives in Diabetes Full Article
be Diet-Induced Type II Diabetes in C57BL/6J Mice By diabetes.diabetesjournals.org Published On :: 1988-09-01 Richard S SurwitSep 1, 1988; 37:1163-1167Original Article Full Article
be Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats By diabetes.diabetesjournals.org Published On :: 1999-12-01 G XuDec 1, 1999; 48:2270-2276Articles Full Article
be Banting Lecture 2001: Dysregulation of Fatty Acid Metabolism in the Etiology of Type 2 Diabetes By diabetes.diabetesjournals.org Published On :: 2002-01-01 J. Denis McGarryJan 1, 2002; 51:7-18Banting Lecture 2001 Full Article
be Elevated Levels of Acute-Phase Proteins and Plasminogen Activator Inhibitor-1 Predict the Development of Type 2 Diabetes: The Insulin Resistance Atherosclerosis Study By diabetes.diabetesjournals.org Published On :: 2002-04-01 Andreas FestaApr 1, 2002; 51:1131-1137Complications Full Article
be Hypoglycemia in the Diabetes Control and Complications Trial By diabetes.diabetesjournals.org Published On :: 1997-02-01 The Diabetes Control and Complications Trial Research GroupFeb 1, 1997; 46:271-286Original Article Full Article
be The Relationship of Glycemic Exposure (HbA1c) to the Risk of Development and Progression of Retinopathy in the Diabetes Control and Complications Trial By diabetes.diabetesjournals.org Published On :: 1995-08-01 The Diabetes Control and Complications Trial Research GroupAug 1, 1995; 44:968-983Original Article Full Article
be Role of oxidative stress in diabetic complications: a new perspective on an old paradigm By diabetes.diabetesjournals.org Published On :: 1999-01-01 JW BaynesJan 1, 1999; 48:1-9Articles Full Article
be Preservation of Pancreatic {beta}-Cell Function and Prevention of Type 2 Diabetes by Pharmacological Treatment of Insulin Resistance in High-Risk Hispanic Women By diabetes.diabetesjournals.org Published On :: 2002-09-01 Thomas A. BuchananSep 1, 2002; 51:2796-2803Pathophysiology Full Article
be U.K. Prospective Diabetes Study 16: Overview of 6 Years' Therapy of Type II Diabetes: A Progressive Disease By diabetes.diabetesjournals.org Published On :: 1995-11-01 U.K. Prospective Diabetes Study GroupNov 1, 1995; 44:1249-1258Perspectives in Diabetes Full Article
be Role of Oxidative Stress in Development of Complications in Diabetes By diabetes.diabetesjournals.org Published On :: 1991-04-01 John W BaynesApr 1, 1991; 40:405-412Perspectives in Diabetes Full Article
be The Triumvirate: {beta}-Cell, Muscle, Liver: A Collusion Responsible for NIDDM By diabetes.diabetesjournals.org Published On :: 1988-06-01 Ralph A DeFronzoJun 1, 1988; 37:667-687Lilly Lecture 1987 Full Article
be Quantification of the Relationship Between Insulin Sensitivity and {beta}-Cell Function in Human Subjects: Evidence for a Hyperbolic Function By diabetes.diabetesjournals.org Published On :: 1993-11-01 Steven E KahnNov 1, 1993; 42:1663-1672Original Article Full Article
be Dysfunction of Mitochondria in Human Skeletal Muscle in Type 2 Diabetes By diabetes.diabetesjournals.org Published On :: 2002-10-01 David E. KelleyOct 1, 2002; 51:2944-2950Metabolism and Signal Transduction Full Article