no Item 01: Notebooks (2) containing hand written copies of 123 letters from Major William Alan Audsley to his parents, ca. 1916-ca. 1919, transcribed by his father. Also includes original letters (2) written by Major Audsley. By feedproxy.google.com Published On :: 28/05/2015 11:00:09 AM Full Article
no Pence aimed to project normalcy during his trip to Iowa, but coronavirus got in the way By news.yahoo.com Published On :: Fri, 08 May 2020 21:35:24 -0400 Vice President Pence’s trip to Iowa shows how the Trump administration’s aims to move past coronavirus are sometimes complicated by the virus itself. Full Article
no 'We Cannot Police Our Way Out of a Pandemic.' Experts, Police Union Say NYPD Should Not Be Enforcing Social Distance Rules Amid COVID-19 By news.yahoo.com Published On :: Thu, 07 May 2020 17:03:38 -0400 The New York City police department (NYPD) is conducting an internal investigation into a May 2 incident involving the violent arrests of multiple people, allegedly members of a group who were not social distancing Full Article
no Bayesian Quantile Regression with Mixed Discrete and Nonignorable Missing Covariates By projecteuclid.org Published On :: Thu, 19 Mar 2020 22:02 EDT Zhi-Qiang Wang, Nian-Sheng Tang. Source: Bayesian Analysis, Volume 15, Number 2, 579--604.Abstract: Bayesian inference on quantile regression (QR) model with mixed discrete and non-ignorable missing covariates is conducted by reformulating QR model as a hierarchical structure model. A probit regression model is adopted to specify missing covariate mechanism. A hybrid algorithm combining the Gibbs sampler and the Metropolis-Hastings algorithm is developed to simultaneously produce Bayesian estimates of unknown parameters and latent variables as well as their corresponding standard errors. Bayesian variable selection method is proposed to recognize significant covariates. A Bayesian local influence procedure is presented to assess the effect of minor perturbations to the data, priors and sampling distributions on posterior quantities of interest. Several simulation studies and an example are presented to illustrate the proposed methodologies. Full Article
no Bayesian Sparse Multivariate Regression with Asymmetric Nonlocal Priors for Microbiome Data Analysis By projecteuclid.org Published On :: Thu, 19 Mar 2020 22:02 EDT Kurtis Shuler, Marilou Sison-Mangus, Juhee Lee. Source: Bayesian Analysis, Volume 15, Number 2, 559--578.Abstract: We propose a Bayesian sparse multivariate regression method to model the relationship between microbe abundance and environmental factors for microbiome data. We model abundance counts of operational taxonomic units (OTUs) with a negative binomial distribution and relate covariates to the counts through regression. Extending conventional nonlocal priors, we construct asymmetric nonlocal priors for regression coefficients to efficiently identify relevant covariates and their effect directions. We build a hierarchical model to facilitate pooling of information across OTUs that produces parsimonious results with improved accuracy. We present simulation studies that compare variable selection performance under the proposed model to those under Bayesian sparse regression models with asymmetric and symmetric local priors and two frequentist models. The simulations show the proposed model identifies important covariates and yields coefficient estimates with favorable accuracy compared with the alternatives. The proposed model is applied to analyze an ocean microbiome dataset collected over time to study the association of harmful algal bloom conditions with microbial communities. Full Article
no Joint Modeling of Longitudinal Relational Data and Exogenous Variables By projecteuclid.org Published On :: Thu, 19 Mar 2020 22:02 EDT Rajarshi Guhaniyogi, Abel Rodriguez. Source: Bayesian Analysis, Volume 15, Number 2, 477--503.Abstract: This article proposes a framework based on shared, time varying stochastic latent factor models for modeling relational data in which network and node-attributes co-evolve over time. Our proposed framework is flexible enough to handle both categorical and continuous attributes, allows us to estimate the dimension of the latent social space, and automatically yields Bayesian hypothesis tests for the association between network structure and nodal attributes. Additionally, the model is easy to compute and readily yields inference and prediction for missing link between nodes. We employ our model framework to study co-evolution of international relations between 22 countries and the country specific indicators over a period of 11 years. Full Article
no Bayesian Inference in Nonparanormal Graphical Models By projecteuclid.org Published On :: Thu, 19 Mar 2020 22:02 EDT Jami J. Mulgrave, Subhashis Ghosal. Source: Bayesian Analysis, Volume 15, Number 2, 449--475.Abstract: Gaussian graphical models have been used to study intrinsic dependence among several variables, but the Gaussianity assumption may be restrictive in many applications. A nonparanormal graphical model is a semiparametric generalization for continuous variables where it is assumed that the variables follow a Gaussian graphical model only after some unknown smooth monotone transformations on each of them. We consider a Bayesian approach in the nonparanormal graphical model by putting priors on the unknown transformations through a random series based on B-splines where the coefficients are ordered to induce monotonicity. A truncated normal prior leads to partial conjugacy in the model and is useful for posterior simulation using Gibbs sampling. On the underlying precision matrix of the transformed variables, we consider a spike-and-slab prior and use an efficient posterior Gibbs sampling scheme. We use the Bayesian Information Criterion to choose the hyperparameters for the spike-and-slab prior. We present a posterior consistency result on the underlying transformation and the precision matrix. We study the numerical performance of the proposed method through an extensive simulation study and finally apply the proposed method on a real data set. Full Article
no A Novel Algorithmic Approach to Bayesian Logic Regression (with Discussion) By projecteuclid.org Published On :: Tue, 17 Mar 2020 04:00 EDT Aliaksandr Hubin, Geir Storvik, Florian Frommlet. Source: Bayesian Analysis, Volume 15, Number 1, 263--333.Abstract: Logic regression was developed more than a decade ago as a tool to construct predictors from Boolean combinations of binary covariates. It has been mainly used to model epistatic effects in genetic association studies, which is very appealing due to the intuitive interpretation of logic expressions to describe the interaction between genetic variations. Nevertheless logic regression has (partly due to computational challenges) remained less well known than other approaches to epistatic association mapping. Here we will adapt an advanced evolutionary algorithm called GMJMCMC (Genetically modified Mode Jumping Markov Chain Monte Carlo) to perform Bayesian model selection in the space of logic regression models. After describing the algorithmic details of GMJMCMC we perform a comprehensive simulation study that illustrates its performance given logic regression terms of various complexity. Specifically GMJMCMC is shown to be able to identify three-way and even four-way interactions with relatively large power, a level of complexity which has not been achieved by previous implementations of logic regression. We apply GMJMCMC to reanalyze QTL (quantitative trait locus) mapping data for Recombinant Inbred Lines in Arabidopsis thaliana and from a backcross population in Drosophila where we identify several interesting epistatic effects. The method is implemented in an R package which is available on github. Full Article
no High-Dimensional Posterior Consistency for Hierarchical Non-Local Priors in Regression By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Xuan Cao, Kshitij Khare, Malay Ghosh. Source: Bayesian Analysis, Volume 15, Number 1, 241--262.Abstract: The choice of tuning parameters in Bayesian variable selection is a critical problem in modern statistics. In particular, for Bayesian linear regression with non-local priors, the scale parameter in the non-local prior density is an important tuning parameter which reflects the dispersion of the non-local prior density around zero, and implicitly determines the size of the regression coefficients that will be shrunk to zero. Current approaches treat the scale parameter as given, and suggest choices based on prior coverage/asymptotic considerations. In this paper, we consider the fully Bayesian approach introduced in (Wu, 2016) with the pMOM non-local prior and an appropriate Inverse-Gamma prior on the tuning parameter to analyze the underlying theoretical property. Under standard regularity assumptions, we establish strong model selection consistency in a high-dimensional setting, where $p$ is allowed to increase at a polynomial rate with $n$ or even at a sub-exponential rate with $n$ . Through simulation studies, we demonstrate that our model selection procedure can outperform other Bayesian methods which treat the scale parameter as given, and commonly used penalized likelihood methods, in a range of simulation settings. Full Article
no Adaptive Bayesian Nonparametric Regression Using a Kernel Mixture of Polynomials with Application to Partial Linear Models By projecteuclid.org Published On :: Mon, 13 Jan 2020 04:00 EST Fangzheng Xie, Yanxun Xu. Source: Bayesian Analysis, Volume 15, Number 1, 159--186.Abstract: We propose a kernel mixture of polynomials prior for Bayesian nonparametric regression. The regression function is modeled by local averages of polynomials with kernel mixture weights. We obtain the minimax-optimal contraction rate of the full posterior distribution up to a logarithmic factor by estimating metric entropies of certain function classes. Under the assumption that the degree of the polynomials is larger than the unknown smoothness level of the true function, the posterior contraction behavior can adapt to this smoothness level provided an upper bound is known. We also provide a frequentist sieve maximum likelihood estimator with a near-optimal convergence rate. We further investigate the application of the kernel mixture of polynomials to partial linear models and obtain both the near-optimal rate of contraction for the nonparametric component and the Bernstein-von Mises limit (i.e., asymptotic normality) of the parametric component. The proposed method is illustrated with numerical examples and shows superior performance in terms of computational efficiency, accuracy, and uncertainty quantification compared to the local polynomial regression, DiceKriging, and the robust Gaussian stochastic process. Full Article
no Latent Nested Nonparametric Priors (with Discussion) By projecteuclid.org Published On :: Thu, 19 Dec 2019 22:10 EST Federico Camerlenghi, David B. Dunson, Antonio Lijoi, Igor Prünster, Abel Rodríguez. Source: Bayesian Analysis, Volume 14, Number 4, 1303--1356.Abstract: Discrete random structures are important tools in Bayesian nonparametrics and the resulting models have proven effective in density estimation, clustering, topic modeling and prediction, among others. In this paper, we consider nested processes and study the dependence structures they induce. Dependence ranges between homogeneity, corresponding to full exchangeability, and maximum heterogeneity, corresponding to (unconditional) independence across samples. The popular nested Dirichlet process is shown to degenerate to the fully exchangeable case when there are ties across samples at the observed or latent level. To overcome this drawback, inherent to nesting general discrete random measures, we introduce a novel class of latent nested processes. These are obtained by adding common and group-specific completely random measures and, then, normalizing to yield dependent random probability measures. We provide results on the partition distributions induced by latent nested processes, and develop a Markov Chain Monte Carlo sampler for Bayesian inferences. A test for distributional homogeneity across groups is obtained as a by-product. The results and their inferential implications are showcased on synthetic and real data. Full Article
no Hierarchical Normalized Completely Random Measures for Robust Graphical Modeling By projecteuclid.org Published On :: Thu, 19 Dec 2019 22:10 EST Andrea Cremaschi, Raffaele Argiento, Katherine Shoemaker, Christine Peterson, Marina Vannucci. Source: Bayesian Analysis, Volume 14, Number 4, 1271--1301.Abstract: Gaussian graphical models are useful tools for exploring network structures in multivariate normal data. In this paper we are interested in situations where data show departures from Gaussianity, therefore requiring alternative modeling distributions. The multivariate $t$ -distribution, obtained by dividing each component of the data vector by a gamma random variable, is a straightforward generalization to accommodate deviations from normality such as heavy tails. Since different groups of variables may be contaminated to a different extent, Finegold and Drton (2014) introduced the Dirichlet $t$ -distribution, where the divisors are clustered using a Dirichlet process. In this work, we consider a more general class of nonparametric distributions as the prior on the divisor terms, namely the class of normalized completely random measures (NormCRMs). To improve the effectiveness of the clustering, we propose modeling the dependence among the divisors through a nonparametric hierarchical structure, which allows for the sharing of parameters across the samples in the data set. This desirable feature enables us to cluster together different components of multivariate data in a parsimonious way. We demonstrate through simulations that this approach provides accurate graphical model inference, and apply it to a case study examining the dependence structure in radiomics data derived from The Cancer Imaging Atlas. Full Article
no Beyond Whittle: Nonparametric Correction of a Parametric Likelihood with a Focus on Bayesian Time Series Analysis By projecteuclid.org Published On :: Thu, 19 Dec 2019 22:10 EST Claudia Kirch, Matthew C. Edwards, Alexander Meier, Renate Meyer. Source: Bayesian Analysis, Volume 14, Number 4, 1037--1073.Abstract: Nonparametric Bayesian inference has seen a rapid growth over the last decade but only few nonparametric Bayesian approaches to time series analysis have been developed. Most existing approaches use Whittle’s likelihood for Bayesian modelling of the spectral density as the main nonparametric characteristic of stationary time series. It is known that the loss of efficiency using Whittle’s likelihood can be substantial. On the other hand, parametric methods are more powerful than nonparametric methods if the observed time series is close to the considered model class but fail if the model is misspecified. Therefore, we suggest a nonparametric correction of a parametric likelihood that takes advantage of the efficiency of parametric models while mitigating sensitivities through a nonparametric amendment. We use a nonparametric Bernstein polynomial prior on the spectral density with weights induced by a Dirichlet process and prove posterior consistency for Gaussian stationary time series. Bayesian posterior computations are implemented via an MH-within-Gibbs sampler and the performance of the nonparametrically corrected likelihood for Gaussian time series is illustrated in a simulation study and in three astronomy applications, including estimating the spectral density of gravitational wave data from the Advanced Laser Interferometer Gravitational-wave Observatory (LIGO). Full Article
no Bayesian Zero-Inflated Negative Binomial Regression Based on Pólya-Gamma Mixtures By projecteuclid.org Published On :: Tue, 11 Jun 2019 04:00 EDT Brian Neelon. Source: Bayesian Analysis, Volume 14, Number 3, 849--875.Abstract: Motivated by a study examining spatiotemporal patterns in inpatient hospitalizations, we propose an efficient Bayesian approach for fitting zero-inflated negative binomial models. To facilitate posterior sampling, we introduce a set of latent variables that are represented as scale mixtures of normals, where the precision terms follow independent Pólya-Gamma distributions. Conditional on the latent variables, inference proceeds via straightforward Gibbs sampling. For fixed-effects models, our approach is comparable to existing methods. However, our model can accommodate more complex data structures, including multivariate and spatiotemporal data, settings in which current approaches often fail due to computational challenges. Using simulation studies, we highlight key features of the method and compare its performance to other estimation procedures. We apply the approach to a spatiotemporal analysis examining the number of annual inpatient admissions among United States veterans with type 2 diabetes. Full Article
no A Bayesian Nonparametric Multiple Testing Procedure for Comparing Several Treatments Against a Control By projecteuclid.org Published On :: Fri, 31 May 2019 22:05 EDT Luis Gutiérrez, Andrés F. Barrientos, Jorge González, Daniel Taylor-Rodríguez. Source: Bayesian Analysis, Volume 14, Number 2, 649--675.Abstract: We propose a Bayesian nonparametric strategy to test for differences between a control group and several treatment regimes. Most of the existing tests for this type of comparison are based on the differences between location parameters. In contrast, our approach identifies differences across the entire distribution, avoids strong modeling assumptions over the distributions for each treatment, and accounts for multiple testing through the prior distribution on the space of hypotheses. The proposal is compared to other commonly used hypothesis testing procedures under simulated scenarios. Two real applications are also analyzed with the proposed methodology. Full Article
no A Bayesian Nonparametric Spiked Process Prior for Dynamic Model Selection By projecteuclid.org Published On :: Wed, 13 Mar 2019 22:00 EDT Alberto Cassese, Weixuan Zhu, Michele Guindani, Marina Vannucci. Source: Bayesian Analysis, Volume 14, Number 2, 553--572.Abstract: In many applications, investigators monitor processes that vary in space and time, with the goal of identifying temporally persistent and spatially localized departures from a baseline or “normal” behavior. In this manuscript, we consider the monitoring of pneumonia and influenza (P&I) mortality, to detect influenza outbreaks in the continental United States, and propose a Bayesian nonparametric model selection approach to take into account the spatio-temporal dependence of outbreaks. More specifically, we introduce a zero-inflated conditionally identically distributed species sampling prior which allows borrowing information across time and to assign data to clusters associated to either a null or an alternate process. Spatial dependences are accounted for by means of a Markov random field prior, which allows to inform the selection based on inferences conducted at nearby locations. We show how the proposed modeling framework performs in an application to the P&I mortality data and in a simulation study, and compare with common threshold methods for detecting outbreaks over time, with more recent Markov switching based models, and with spike-and-slab Bayesian nonparametric priors that do not take into account spatio-temporal dependence. Full Article
no Constrained Bayesian Optimization with Noisy Experiments By projecteuclid.org Published On :: Wed, 13 Mar 2019 22:00 EDT Benjamin Letham, Brian Karrer, Guilherme Ottoni, Eytan Bakshy. Source: Bayesian Analysis, Volume 14, Number 2, 495--519.Abstract: Randomized experiments are the gold standard for evaluating the effects of changes to real-world systems. Data in these tests may be difficult to collect and outcomes may have high variance, resulting in potentially large measurement error. Bayesian optimization is a promising technique for efficiently optimizing multiple continuous parameters, but existing approaches degrade in performance when the noise level is high, limiting its applicability to many randomized experiments. We derive an expression for expected improvement under greedy batch optimization with noisy observations and noisy constraints, and develop a quasi-Monte Carlo approximation that allows it to be efficiently optimized. Simulations with synthetic functions show that optimization performance on noisy, constrained problems outperforms existing methods. We further demonstrate the effectiveness of the method with two real-world experiments conducted at Facebook: optimizing a ranking system, and optimizing server compiler flags. Full Article
no A Bayesian Approach to Statistical Shape Analysis via the Projected Normal Distribution By projecteuclid.org Published On :: Wed, 13 Mar 2019 22:00 EDT Luis Gutiérrez, Eduardo Gutiérrez-Peña, Ramsés H. Mena. Source: Bayesian Analysis, Volume 14, Number 2, 427--447.Abstract: This work presents a Bayesian predictive approach to statistical shape analysis. A modeling strategy that starts with a Gaussian distribution on the configuration space, and then removes the effects of location, rotation and scale, is studied. This boils down to an application of the projected normal distribution to model the configurations in the shape space, which together with certain identifiability constraints, facilitates parameter interpretation. Having better control over the parameters allows us to generalize the model to a regression setting where the effect of predictors on shapes can be considered. The methodology is illustrated and tested using both simulated scenarios and a real data set concerning eight anatomical landmarks on a sagittal plane of the corpus callosum in patients with autism and in a group of controls. Full Article
no Statistical Inference for the Evolutionary History of Cancer Genomes By projecteuclid.org Published On :: Tue, 03 Mar 2020 04:00 EST Khanh N. Dinh, Roman Jaksik, Marek Kimmel, Amaury Lambert, Simon Tavaré. Source: Statistical Science, Volume 35, Number 1, 129--144.Abstract: Recent years have seen considerable work on inference about cancer evolution from mutations identified in cancer samples. Much of the modeling work has been based on classical models of population genetics, generalized to accommodate time-varying cell population size. Reverse-time, genealogical views of such models, commonly known as coalescents, have been used to infer aspects of the past of growing populations. Another approach is to use branching processes, the simplest scenario being the classical linear birth-death process. Inference from evolutionary models of DNA often exploits summary statistics of the sequence data, a common one being the so-called Site Frequency Spectrum (SFS). In a bulk tumor sequencing experiment, we can estimate for each site at which a novel somatic point mutation has arisen, the proportion of cells that carry that mutation. These numbers are then grouped into collections of sites which have similar mutant fractions. We examine how the SFS based on birth-death processes differs from those based on the coalescent model. This may stem from the different sampling mechanisms in the two approaches. However, we also show that despite this, they are quantitatively comparable for the range of parameters typical for tumor cell populations. We also present a model of tumor evolution with selective sweeps, and demonstrate how it may help in understanding the history of a tumor as well as the influence of data pre-processing. We illustrate the theory with applications to several examples from The Cancer Genome Atlas tumors. Full Article
no Data Denoising and Post-Denoising Corrections in Single Cell RNA Sequencing By projecteuclid.org Published On :: Tue, 03 Mar 2020 04:00 EST Divyansh Agarwal, Jingshu Wang, Nancy R. Zhang. Source: Statistical Science, Volume 35, Number 1, 112--128.Abstract: Single cell sequencing technologies are transforming biomedical research. However, due to the inherent nature of the data, single cell RNA sequencing analysis poses new computational and statistical challenges. We begin with a survey of a selection of topics in this field, with a gentle introduction to the biology and a more detailed exploration of the technical noise. We consider in detail the problem of single cell data denoising, sometimes referred to as “imputation” in the relevant literature. We discuss why this is not a typical statistical imputation problem, and review current approaches to this problem. We then explore why the use of denoised values in downstream analyses invites novel statistical insights, and how denoising uncertainty should be accounted for to yield valid statistical inference. The utilization of denoised or imputed matrices in statistical inference is not unique to single cell genomics, and arises in many other fields. We describe the challenges in this type of analysis, discuss some preliminary solutions, and highlight unresolved issues. Full Article
no Statistical Molecule Counting in Super-Resolution Fluorescence Microscopy: Towards Quantitative Nanoscopy By projecteuclid.org Published On :: Tue, 03 Mar 2020 04:00 EST Thomas Staudt, Timo Aspelmeier, Oskar Laitenberger, Claudia Geisler, Alexander Egner, Axel Munk. Source: Statistical Science, Volume 35, Number 1, 92--111.Abstract: Super-resolution microscopy is rapidly gaining importance as an analytical tool in the life sciences. A compelling feature is the ability to label biological units of interest with fluorescent markers in (living) cells and to observe them with considerably higher resolution than conventional microscopy permits. The images obtained this way, however, lack an absolute intensity scale in terms of numbers of fluorophores observed. In this article, we discuss state of the art methods to count such fluorophores and statistical challenges that come along with it. In particular, we suggest a modeling scheme for time series generated by single-marker-switching (SMS) microscopy that makes it possible to quantify the number of markers in a statistically meaningful manner from the raw data. To this end, we model the entire process of photon generation in the fluorophore, their passage through the microscope, detection and photoelectron amplification in the camera, and extraction of time series from the microscopic images. At the heart of these modeling steps is a careful description of the fluorophore dynamics by a novel hidden Markov model that operates on two timescales (HTMM). Besides the fluorophore number, information about the kinetic transition rates of the fluorophore’s internal states is also inferred during estimation. We comment on computational issues that arise when applying our model to simulated or measured fluorescence traces and illustrate our methodology on simulated data. Full Article
no Quantum Science and Quantum Technology By projecteuclid.org Published On :: Tue, 03 Mar 2020 04:00 EST Yazhen Wang, Xinyu Song. Source: Statistical Science, Volume 35, Number 1, 51--74.Abstract: Quantum science and quantum technology are of great current interest in multiple frontiers of many scientific fields ranging from computer science to physics and chemistry, and from engineering to mathematics and statistics. Their developments will likely lead to a new wave of scientific revolutions and technological innovations in a wide range of scientific studies and applications. This paper provides a brief review on quantum communication, quantum information, quantum computation, quantum simulation, and quantum metrology. We present essential quantum properties, illustrate relevant concepts of quantum science and quantum technology, and discuss their scientific developments. We point out the need for statistical analysis in their developments, as well as their potential applications to and impacts on statistics and data science. Full Article
no Gaussianization Machines for Non-Gaussian Function Estimation Models By projecteuclid.org Published On :: Wed, 08 Jan 2020 04:00 EST T. Tony Cai. Source: Statistical Science, Volume 34, Number 4, 635--656.Abstract: A wide range of nonparametric function estimation models have been studied individually in the literature. Among them the homoscedastic nonparametric Gaussian regression is arguably the best known and understood. Inspired by the asymptotic equivalence theory, Brown, Cai and Zhou ( Ann. Statist. 36 (2008) 2055–2084; Ann. Statist. 38 (2010) 2005–2046) and Brown et al. ( Probab. Theory Related Fields 146 (2010) 401–433) developed a unified approach to turn a collection of non-Gaussian function estimation models into a standard Gaussian regression and any good Gaussian nonparametric regression method can then be used. These Gaussianization Machines have two key components, binning and transformation. When combined with BlockJS, a wavelet thresholding procedure for Gaussian regression, the procedures are computationally efficient with strong theoretical guarantees. Technical analysis given in Brown, Cai and Zhou ( Ann. Statist. 36 (2008) 2055–2084; Ann. Statist. 38 (2010) 2005–2046) and Brown et al. ( Probab. Theory Related Fields 146 (2010) 401–433) shows that the estimators attain the optimal rate of convergence adaptively over a large set of Besov spaces and across a collection of non-Gaussian function estimation models, including robust nonparametric regression, density estimation, and nonparametric regression in exponential families. The estimators are also spatially adaptive. The Gaussianization Machines significantly extend the flexibility and scope of the theories and methodologies originally developed for the conventional nonparametric Gaussian regression. This article aims to provide a concise account of the Gaussianization Machines developed in Brown, Cai and Zhou ( Ann. Statist. 36 (2008) 2055–2084; Ann. Statist. 38 (2010) 2005–2046), Brown et al. ( Probab. Theory Related Fields 146 (2010) 401–433). Full Article
no A Conversation with Noel Cressie By projecteuclid.org Published On :: Thu, 18 Jul 2019 22:01 EDT Christopher K. Wikle, Jay M. Ver Hoef. Source: Statistical Science, Volume 34, Number 2, 349--359.Abstract: Noel Cressie, FAA is Director of the Centre for Environmental Informatics in the National Institute for Applied Statistics Research Australia (NIASRA) and Distinguished Professor in the School of Mathematics and Applied Statistics at the University of Wollongong, Australia. He is also Adjunct Professor at the University of Missouri (USA), Affiliate of Org 398, Science Data Understanding, at NASA’s Jet Propulsion Laboratory (USA), and a member of the Science Team for NASA’s Orbiting Carbon Observatory-2 (OCO-2) satellite. Cressie was awarded a B.Sc. with First Class Honours in Mathematics in 1972 from the University of Western Australia, and an M.A. and Ph.D. in Statistics in 1973 and 1975, respectively, from Princeton University (USA). Two brief postdoctoral periods followed, at the Centre de Morphologie Mathématique, ENSMP, in Fontainebleau (France) from April 1975–September 1975, and at Imperial College, London (UK) from September 1975–January 1976. His past appointments have been at The Flinders University of South Australia from 1976–1983, at Iowa State University (USA) from 1983–1998, and at The Ohio State University (USA) from 1998–2012. He has authored or co-authored four books and more than 280 papers in peer-reviewed outlets, covering areas that include spatial and spatio-temporal statistics, environmental statistics, empirical-Bayesian and Bayesian methods including sequential design, goodness-of-fit, and remote sensing of the environment. Many of his papers also address important questions in the sciences. Cressie is a Fellow of the Australian Academy of Science, the American Statistical Association, the Institute of Mathematical Statistics, and the Spatial Econometrics Association, and he is an Elected Member of the International Statistical Institute. Noel Cressie’s refereed, unrefereed, and other publications are available at: https://niasra.uow.edu.au/cei/people/UOW232444.html. Full Article
no Statistical Analysis of Zero-Inflated Nonnegative Continuous Data: A Review By projecteuclid.org Published On :: Thu, 18 Jul 2019 22:01 EDT Lei Liu, Ya-Chen Tina Shih, Robert L. Strawderman, Daowen Zhang, Bankole A. Johnson, Haitao Chai. Source: Statistical Science, Volume 34, Number 2, 253--279.Abstract: Zero-inflated nonnegative continuous (or semicontinuous) data arise frequently in biomedical, economical, and ecological studies. Examples include substance abuse, medical costs, medical care utilization, biomarkers (e.g., CD4 cell counts, coronary artery calcium scores), single cell gene expression rates, and (relative) abundance of microbiome. Such data are often characterized by the presence of a large portion of zero values and positive continuous values that are skewed to the right and heteroscedastic. Both of these features suggest that no simple parametric distribution may be suitable for modeling such type of outcomes. In this paper, we review statistical methods for analyzing zero-inflated nonnegative outcome data. We will start with the cross-sectional setting, discussing ways to separate zero and positive values and introducing flexible models to characterize right skewness and heteroscedasticity in the positive values. We will then present models of correlated zero-inflated nonnegative continuous data, using random effects to tackle the correlation on repeated measures from the same subject and that across different parts of the model. We will also discuss expansion to related topics, for example, zero-inflated count and survival data, nonlinear covariate effects, and joint models of longitudinal zero-inflated nonnegative continuous data and survival. Finally, we will present applications to three real datasets (i.e., microbiome, medical costs, and alcohol drinking) to illustrate these methods. Example code will be provided to facilitate applications of these methods. Full Article
no We thank you for not smoking / design : Biman Mullick. By search.wellcomelibrary.org Published On :: London (33 Stillness Rd, London, SE23 1NG) : Cleanair, Campaign for a Smoke-free Environment, [198-?] Full Article
no Cleanair not smoke / design : Biman Mullick. By search.wellcomelibrary.org Published On :: London : Cleanair, Smoke-free Environment (33 Stillness Rd, London, SE23 1NG), [198-?] Full Article
no No smoking no hate / Biman Mullick. By search.wellcomelibrary.org Published On :: London : Cleanair, Smoke-free Environment (33 Stillness Rd, London, SE23 1NG), [198-?] Full Article
no No smoking zone / design : Biman Mullick. By search.wellcomelibrary.org Published On :: London : Cleanair, Smoke-free Environment (33 Stillness Rd, London, SE23 1NG), [198-?] Full Article
no No smoking is the norm / design : Biman Mullick. By search.wellcomelibrary.org Published On :: London : Cleanair, Smoke-free Environment (33 Stillness Rd, London, SE23 1NG), [198-?] Full Article
no We thank you for not smoking / design : Biman Mullick. By search.wellcomelibrary.org Published On :: London (33 Stillness Rd, London, SE23 1NG) : Cleanair, Campaign for a Smoke-free Environment, [198-?] Full Article
no No smoking zone / design : Biman Mullick. By search.wellcomelibrary.org Published On :: London : Cleanair, Smoke-free Environment (33 Stillness Rd, London, SE23 1NG), [198-?] Full Article
no We thank you for not smoking / Biman Mullick. By search.wellcomelibrary.org Published On :: London : Cleanair, [1988?] Full Article
no Muchas gracias por no fumar / Biman Mullick. By search.wellcomelibrary.org Published On :: London : Cleanair, [1988?] Full Article
no We thank you for not smoking / design : Biman Mullick. By search.wellcomelibrary.org Published On :: London (33 Stillness Rd, London, SE23 1NG) : Cleanair, Campaign for a Smoke-free Environment, [198-?] Full Article
no No smoking is the norm / design : Biman Mullick. By search.wellcomelibrary.org Published On :: London : Cleanair, Smoke-free Environment (33 Stillness Rd, London, SE23 1NG), [198-?] Full Article
no Gracias por no fumar / deseño : Biman Mullick. By search.wellcomelibrary.org Published On :: [London] : Cleanair, Campaña para un Medio Ambiente Libre de Humo, [198-?] Full Article
no No fumar es la moda / deseño : Biman Mullick. By search.wellcomelibrary.org Published On :: [London] : Cleanair, Campaña para un Medio Ambiente Libre de Humo, [198-?] Full Article
no Muchas gracias por no fumar / Biman Mullick. By search.wellcomelibrary.org Published On :: [London] : Cleanair, [1989?] Full Article
no Zona de no fumar / deseño : Biman Mullick. By search.wellcomelibrary.org Published On :: London : Cleanair Campaña para un Medio Ambiente Libre de Humo, [198-?] Full Article
no How can the smoker and the nonsmoker be equally free in the same place? George Bernard Shaw / Biman Mullick. By search.wellcomelibrary.org Published On :: [London?], [199-?] Full Article
no Danny Smith from No Human Being Is Illegal (in all our glory). Collaged photograph by Deborah Kelly and collaborators, 2014-2018. By search.wellcomelibrary.org Published On :: [London], 2019. Full Article
no Blake Lively's Favorite Affordable Jeans Brand Is Having a Major Sale Right Now By www.health.com Published On :: Mon, 25 Nov 2019 16:40:00 -0500 Here's everything you need to know about Old Navy's Black Friday and Cyber Monday plans. Full Article
no These Nordstrom Cyber Monday Deals Are Giving Black Friday a Run for Its Money By www.health.com Published On :: Wed, 21 Nov 2018 10:40:05 -0500 This is not a drill: You can get up to 50% off at Nordstrom right now. Full Article
no These Clark Booties Are Actually Comfortable Enough to Wear All Day—and They’re on Sale By www.health.com Published On :: Sun, 08 Dec 2019 09:36:02 -0500 You can save 50% right now. Full Article
no Multisensory Integration and the Society for Neuroscience: Then and Now By www.jneurosci.org Published On :: 2020-01-02 Barry E. SteinJan 2, 2020; 40:3-11Viewpoints Full Article
no Genomic Analysis of Reactive Astrogliosis By www.jneurosci.org Published On :: 2012-05-02 Jennifer L. ZamanianMay 2, 2012; 32:6391-6410Neurobiology of Disease Full Article
no Sleep Deprivation Biases the Neural Mechanisms Underlying Economic Preferences By www.jneurosci.org Published On :: 2011-03-09 Vinod VenkatramanMar 9, 2011; 31:3712-3718BehavioralSystemsCognitive Full Article
no {Delta}9-Tetrahydrocannabinol and Cannabinol Activate Capsaicin-Sensitive Sensory Nerves via a CB1 and CB2 Cannabinoid Receptor-Independent Mechanism By www.jneurosci.org Published On :: 2002-06-01 Peter M. ZygmuntJun 1, 2002; 22:4720-4727Behavioral Full Article
no Daily Marijuana Use Is Not Associated with Brain Morphometric Measures in Adolescents or Adults By www.jneurosci.org Published On :: 2015-01-28 Barbara J. WeilandJan 28, 2015; 35:1505-1512Neurobiology of Disease Full Article