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New weight loss drug target reduces appetite and burns calories without sickness

The discovery could lead to a new treatment for millions of people with obesity and type 2 diabetes who do not respond well to current treatments.













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'Massive downsizing': Vivek Ramaswamy reveals how he will ensure government efficiency under Trump - The Times of India

  1. 'Massive downsizing': Vivek Ramaswamy reveals how he will ensure government efficiency under Trump  The Times of India
  2. DOGE days are coming for the US under Trump's two Musketeers  The Times of India
  3. Trump picks Musk, Ramaswamy to run new dept of govt efficiency  Hindustan Times
  4. When Vivek Ramaswamy was 18: School speech emerges as he readies for DOGE role  India Today
  5. Explained: How Musk's US Government Efficiency Panel Might Work  NDTV










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Biden highlights 'peaceful transfer of power' as he hosts president-elect...


Biden highlights 'peaceful transfer of power' as he hosts president-elect...


(Top headline, 1st story, link)


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‘Emilia Pérez’ interview: Director Jacques Audiard on Karla Sofía Gascón and the operatic influences of writing a musical

Following its Cannes-winning run, French director Jacques Audiard talks about how ‘Emilia Pérez’ reshapes the musical genre, with its lead star’s dazzling spectacle of contradiction and rebirth




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Actor Rupali Ganguly files ₹50 crore defamation suit against stepdaughter Esha Verma

Rupali Ganguly, known for the Hindi serial ‘Anupamaa’, has filed Rs 50 crore defamation suit against stepdaughter Esha Verma for “false and damaging statements”




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Karnataka Chitrakala Parishath remembers Nicholas Roerich with exhibition on till November 18

Roerich was an artist whose life and art bridged Russian and Indian cultural traditions.




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Vroooom, an interactive virtual reality film festival in Hyderabad

Experience interactive storytelling at Vroooom, the virtual reality film festival presented by Goethe Zentrum Hyderabad and Annapurna College of Film and Media




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Unni Mukundan’s ‘Marco’ locks a release date

Directed by Haneef Adeni, ‘Marco’ is a spin-off of Unni’s character in the director’s 2019 film, ‘Mikhael’




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Sumukhi Suresh on humour, health, and her upcoming stand-up special, ‘Hoemonal’

In ‘Hoemonal,’ Sumukhi Suresh brings to the stage, candid comedy on health, singlehood, and resilience, and tackling taboos with humor that resonates beyond laughs




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‘Bandish Bandits’ Season 2 to premiere on Prime Video in December

Created by Amritpal Singh Bindra and Anand Tiwari, the romantic drama show features actors Ritwik Bhowmik and Shreya Chaudhry as Radhe and Tamanna, two musicians who come from different worlds of music




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Singapore-Tamil rapper Yung Raja on why he loves visiting India, and his single ‘Podu Mike’

Dialects, aspirations, collaborations and sounds of his motherland are keeping Singaporean-Tamil rapper Yung Raja going this year




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‘Emilia Pérez’ movie review: Karla Sofia Gascón, Zoe Saldaña’s narco-musical melange is an acquired taste

The feverish Cannes-winning spectacle dazzles with audacity but stumbles under the weight of its own ambition




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Kanguva can be released on November 14, orders Madras High Court

Justices G. Jayachandran and C.V. Karthikeyan clear the decks after the producer deposits ₹6.41 crore on Wednesday





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Alison Hammond produces ‘TV gold’ with dramatic fall on Great British Bake Off

Noel Fielding called the moment ‘the best thing I’ve ever seen’




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The Voice US contestant shares cryptic response after suddenly quitting show

Singer was one of the early favourites to win the talent show




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Outnumbered cast are all grown up in new BBC reunion photo

The kids from the BBC sitcom are all in their twenties now




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The Penguin achieves incredibly rare viewership and Rotten Tomatoes feat

The series has transcended expectations in a huge way




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Timothy West death: Star of stage and screen dies, aged 90

West was a star of the stage and the screen and died in his sleep, his children have announced




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Dancing with the Stars recap: Who went home in week 8’s elimination?

Season 33 welcomed a new cast of celebrity contestants all competing for the coveted Mirrorball trophy




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Full House star Dave Coulier reveals diagnosis with ‘very aggressive’ cancer

Actor, who played Joey Gladstone on the hit ABC sitcom, said he is currently undergoing rounds of chemotherapy




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Why agents are the next step in transforming your business with gen AI

The rise of generative AI (gen AI) and ChatGPT has brought large language models (LLMs) to the forefront of technological innovation. Unlike traditional AI, these LLMs can process and generate language in a way that mimics human reasoning. Businesses are leveraging this technology in various ways, including content generation, customer service interactions, and document summarization. Gen AI offers businesses a chance to streamline operations and improve efficiency. However, LLMs are not universally…




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Preparing your organization for AI: 6 essential data strategies

As organizations increasingly adopt AI, ensuring that data quality is optimized is paramount for success. Good data is not just an asset; it serves as the foundation for effective AI models. High-quality data influences cost-efficiency, reliable decision-making and scalability. In this article, we will explore six data strategies that can prepare your organization for AI adoption. 1. Detect anomalies in your data Anomaly detection refers to identifying data points that deviate from expected patterns.…




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Tyto Athene acquires Key Solutions to boost government contract wins

The government contractor's deal is part of a growing strategy focused on acquiring other firms.




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Wolfspeed lawsuit claims scientists took trade secrets to competitor

Durham manufacturer Wolfspeed is suing a pair of former longtime employees.




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SBR issues consensus on interchangeability of reference products and biosimilars

<p>On 25 September&nbsp;2024, the Brazilian Society of Rheumatology (SBR,&nbsp;<i>Sociedade Brasileira de Reumatologia</i>) shared its position&nbsp;and consensus&nbsp;on the interchangeability between reference products and biosimilars, a topic of great importance for clinical practice, especially in light of recent regulatory developments by&nbsp;Brazilian Health Regulatory Agency, ANVISA (<i>Agência Nacional de Vigilância Sanitária</i>)&nbsp;and other international authorities.&nbsp;</p>




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'I want to leave a beautiful memory of them': Jack Neo's parents cameo in new CNY movie I Want To Be Boss

Wedding bells rang at Trinity Methodist Church yesterday afternoon (Nov 12) as couples renewed their vows — but it was all for a scene in local director Jack Neo's upcoming movie, I Want To Be Boss. Among them, however, was an actual couple who have been married for more than six decades — Jack's very own parents. "I want to leave a beautiful memory of them in the movie," the 64-year-old actor-director told local media on the set. His mum, 86, was dressed in a white wedding gown with tulle sleeves, while Jack's father, 91, looked sharp in a black suit with a matching bowtie. Jack added: "I especially requested that my mum put on a wedding dress today for this scene, because the first time they wore their wedding outfits, I only got to see them in photos. I can see them now."




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Singapore actor Chin Han joins cast of Netflix series Avatar: The Last Airbender

Netflix has expanded the cast of live-action series Avatar: The Last Airbender in its second season, with Singapore actor Chin Han one of the latest eight additions. He will play the role of Long Feng — leader of Dai Li, the secret police force of Ba Sing Se, or the capital of the Earth Kingdom. Another new joiner is Taiwanese-American actor Justin Chien, who starred with Malaysian actress Michelle Yeoh in the Netflix series The Brothers Sun (2024) and will play King Kuei, ruler of the Earth Kingdom in Avatar: The Last Airbender. Meanwhile, Vietnamese-Australian actor Hoa Xuande, who starred with American actor Robert Downey Jr in the HBO miniseries The Sympathizer (2024), will play Professor Zei, head of the anthropology department at Ba Sing Se University.  Other actors in the cast are Amanda Zhou as Joo Dee, Crystal Yu as Lady Beifong, Kelemete Misipeka as The Boulder, Lourdes Faberes as General Sung and Rekha Sharma as Amita.




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15 arrested in multi-agency raid on Joo Chiat public entertainment outlets

12 men and three women, aged between 19 and 63, were arrested for various offences during a multi-agency enforcement operation against errant public entertainment outlets on Friday (Nov 8) night. The offences include working without a valid work permit, suspected drink driving, driving without a valid license and insurance, suspected consumption and possession of controlled drugs, and the possession of scheduled weapons.  Members of the media, including AsiaOne, were invited to observe the enforcement operations, led by Bedok Police Division, in Joo Chiat on Friday night.  The enforcement operation is part of their ongoing efforts to clamp down on illicit activities and regulatory offences in the area, said the police in a statement on Wednesday. Upon arriving at the scene just after midnight on Saturday, members of the media were led to the second floor of the first KTV outlet. 




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SAF's training area in Australia now 5 times Singapore's size, marking a 'historic milestone': Heng Chee How

SHOALWATER BAY, Australia - The expansion of the Shoalwater Bay Training Area (SWBTA) in Queensland has been completed after eight years of development. With the expanded training area now five times the size of Singapore, this means that the scale and complexity of overseas exercises involving the Singapore Armed Forces (SAF) can be increased in the future, Senior Minister of State for Defence Heng Chee How said on Wednesday (Nov 13). Heng was speaking to reporters after witnessing Singaporean and Australian soldiers being put through their paces during a simulated beach landing as part of Exercise Trident. He also flew on a CH-47F chinook to view the new facilities within the expanded SWBTA and interacted with SAF and the Australian Defence Force (ADF) soldiers who participated in the bilateral exercise. Jointly developed by Australia and Singapore since 2016, the expansion of the overall training area was set out in a treaty between the two countries in 2020. State-of-the-art facilities such as the combined arms air-land ranges and urban operations live-firing facilities have been included in the expansion.




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Woman brandishes knife in clash with couple over rental deposit for Yishun condo

After their rental agreement with a sublessor fell through, a couple asked for their deposit to be returned. They waited three weeks to no avail and decided to visit the sublessor's home for discussions. But the negotiations turned physical, with the woman brandishing a knife at the couple after she was attacked. The incident occurred at about 7pm last Sunday (Nov 10) at a condominium in Yishun, reported Shin Min Daily News. Chen, 41, said he had seen an advertisement for the four-bedroom unit on Oct 13 and contacted the poster, who said she had rented the apartment from the original tenant. The woman told Chen she could sublet the unit to him and his wife if the homeowner was agreeable to it.  After viewing pictures and videos of the apartment, the man immediately made a PayNow transfer of $1,000 to the woman as deposit. The couple viewed the unit the next day, where both parties discussed the rental agreement in detail. A week later, however, the woman told them that she had not gotten the approval of the condo owner to sublet the apartment.




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Ex-Philippine President Duterte says ICC should 'hurry up' on drug war investigation

MANILA — Former Philippine President Rodrigo Duterte said the International Criminal Court (ICC) should 'hurry up' with its probe of his war on drugs, remaining firm in his defence of the brutal campaign as he said the investigation should start immediately."I'm asking the ICC to hurry up, and if possible, they can come here and start the investigation tomorrow," Duterte said in a congressional inquiry on his war on drugs. "If I am found guilty, I will go to prison." According to police data, more than 6,200 people died in anti-drug operations under Duterte's presidency, during which police typically said they had killed suspects in self-defence. Human rights groups believe the real toll to be far greater, with thousands more users and small-time peddlers killed in mysterious circumstances by unknown assailants. "I assume full responsibility for whatever happened in the actions taken by law enforcement agencies of this country to... stop the serious problem of drugs affecting our people," Duterte said. The ICC last year cleared the way for an investigation to into the thousands of deaths and other suspected rights abuses.




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Sri Lanka's first transgender candidate hopes to break political, social barriers

COLOMBO — Chanu Nimesha is contesting Sri Lanka's parliamentary election on Thursday (Nov 14) as the first openly transgender candidate, hoping to forge a more inclusive and tolerant political culture on the South Asian island. Transgender people are estimated to make up about one per cent of Sri Lanka's 22 million people, according to Equal Ground, a local civil society group. They frequently face social rejection, lack legal protection and have almost no representation in political parties. Nimesha, who is contesting from Kegalle — about 80km east of Colombo — said she was the first transgender person to run for a seat in the 225-strong parliament and that her message of social justice had been well received. "I'm not concerned about winning or losing," she said, sitting in her one-bedroom flat. "But it is important for me to be present in this space, to be seen, to inspire others like me. I want to help everyone, not just my community."