Analyst, 2024, 149,5287-5297
DOI: 10.1039/D4AN00916A, Paper

Jian Song, Wenlong Liang, Hongtao Huang, Hongyan Jia, Shouning Yang, Chunlei Wang, Huayan Yang
A novel feature-extractor-based fusion-assisted machine learning strategy was developed for high accuracy and rapid strain differentiation using MALDI-TOF MS and Raman spectra.
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Analyst, 2024, 149,5232-5242
DOI: 10.1039/D4AN00958D, Paper

Xuyang Ma, Liqiang Liu, Shanshan Song, Hua Kuang, Chuanlai Xu, Xinxin Xu
The determination of glyphosate in soybean (a) and corn (b) samples using a lateral strip assay.
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Analyst, 2024, 149,5277-5286
DOI: 10.1039/D4AN00649F, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Naghmeh Aboualigaledari, Anitha Jayapalan, Panesun Tukur, Mengxin Liu, Frank Tukur, Yanling Zhang, Gerald Ducatte, Madan Verma, Janet Tarus, Simona E. Hunyadi Murph, Jianjun Wei
Hybrid nanoparticles composed of gold nanoparticles and carbon nanodots provide great signal amplification in SERS detection of herbicide molecules.
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Analyst, 2024, 149,5298-5305
DOI: 10.1039/D4AN00995A, Paper

Keqi Ye, Jiacheng Ye, Yinghua Yan, Chuan-Fan Ding
This work introduces rapid quantification of disaccharide isomers by derivatization in combination with ion mobility spectrometry in beer and milk.
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Analyst, 2024, 149,5265-5276
DOI: 10.1039/D4AN01102C, Paper

Longmei Yao, Xue Mei, Jiajia Zhi, Wenchang Wang, Qingyi Li, Ding Jiang, Xiaohui Chen, Zhidong Chen
In this study, a novel electrochemiluminescent (ECL) sensor for highly sensitive detection of trilobatin (Tri) was developed based on silver metal–organic frameworks (AgMOFs) and nitrogen-doped carbon quantum dots (N-CDs).
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Analyst, 2024, 149,5306-5312
DOI: 10.1039/D4AN00747F, Paper

Qun Wu, Chengbin Liu, Yifan Liu, Tao Li
A fluorescent probe for live-cell imaging of nitric oxide (NO) allows for sensitive detection of NO in cancer cells, thereby enabling real-time monitoring of doxorubicin-induced apoptosis and lipopolysaccharide-triggered inflammatory responses.
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Analyst, 2024, 149,5206-5212
DOI: 10.1039/D4AN01165A, Paper

Xueying Zhu, Tikai Liang, Dianping Tang
A highly efficient photoelectrochemical (PEC) strategy was proposed for the determination of ascorbic acid (AA).
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Analyst, 2024, 149,5191-5205
DOI: 10.1039/D4AN01061B, Paper

Ahmad Hasan As'ari, Rizky Aflaha, Laila Katriani, Ahmad Kusumaatmaja, Iman Santoso, Rike Yudianti, Kuwat Triyana
Utilizing the specific interaction between carboxylic groups and ammonia gas has led to the development of an ultra-sensitive ammonia sensor based on a quartz crystal microbalance using nanofibers overlaid with carboxylic group-functionalized MWCNTs.
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Analyst, 2024, 149,5320-5328
DOI: 10.1039/D4AN00961D, Paper

Yusuke Hibi
Nonlinear reference-free analysis in pyrolysis-MS enables accurate compositional analysis even in reactive and interactive systems.
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Analyst, 2024, 149,5174-5183
DOI: 10.1039/D4AN00996G, Paper

Takafumi Hirata, Kyoko Kobayashi, Hui Hsin Khoo, Osamu Shikino, Hisashi Asanuma
A new analytical technique for detection of organic compounds using inductively coupled plasma-tandem mass spectrometry (ICP-MS/MS) is described.
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Analyst, 2024, 149,5313-5319
DOI: 10.1039/D4AN00946K, Paper

Wei Xu, Lichun Zou, Haiyan Wang, Changhui Xu, Qinyang Fan, Jingjie Sha
The efficient identification and validation of drug targets are paramount in drug discovery and development.
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Analyst, 2024, 149,5156-5164
DOI: 10.1039/D4AN01109K, Minireview

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Derya Yaman, Melanie Jimenez, Sofia Ferreira Gonzalez, Damion Corrigan
Electrochemical detection of liver biomarkers, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), bilirubin, gamma-glutamyl transferase (GGT), alkaline phosphatase (ALP), and albumin, all with vital physiological functions.
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Analyst, 2024, 149,5213-5224
DOI: 10.1039/D4AN01028K, Paper

Kaihao Mao, Ye Tao, Wenshang Guo, Qisheng Yang, Meiying Zhao, Xiangyu Meng, Yinghao Zhang, Yukun Ren
An automated microscope image detection device (A-MMD) is designed to detect fluorescent droplets in droplet digital PCR images captured by multiple microscopes.
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Analyst, 2024, 149,5336-5343
DOI: 10.1039/D4AN00828F, Paper

Timothy T. Salomons, David Simon, Richard Oleschuk
A micro-fractionation device to archive liquid chromatographic separations on an array of surface energy traps.
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Analyst, 2024, 149,5344-5352
DOI: 10.1039/D4AN01050G, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Auraya Manaprasertsak, Julhash U. Kazi, Catharina Hagerling, Kenneth J. Pienta, Per Malmberg, Emma U. Hammarlund
This study uses Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) to analyze cholesterol alterations in cancer tissue, revealing changes in fragmentation and isotopes that suggest potential diagnostic vulnerabilities.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00957F, Tutorial Review

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Kan-Zhi Liu, Ganghong Tian, Alex C.-T. Ko, Matthias Geissler, Lidija Malic, Byeong-Ui Moon, Liviu Clime, Teodor Veres
We review emerging methods for the detection of acute respiratory tract infections using microfluidic technologies.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00983E, Paper

Kwanhwi Ko, Hajun Yoo, Sangheon Han, Won Seok Chang, Donghyun Kim
The combination of dielectrophoresis and surface-enhanced Raman spectroscopy provides an effective method for analyzing the Raman characteristics and the dielectrophoretic behavior of polystyrene beads and U-87MG cells in a microfluidic environment.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01160K, Paper

Maria Nikitina, Pavel Khramtsov, Stepan Devyatov, Rishat Valeev, Marina Eryomina, Andrey Chukavin, Mikhail Rayev
LaNiO₃ nanosphere-based NLISA has been demonstrated for the first time. The assay enables the CRP effective detection with high sensitivity.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00964A, Paper

Feng-yan Kuang, De-jun Hu, Lu Wang, Fei Chen, Guang-ping Lv
The selection of the matrix is crucial for matrix assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI).
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Analyst, 2024, Accepted Manuscript
DOI: 10.1039/D4AN01082E, Critical Review

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Jagpreet Singh Sidhu, Gurjot Kaur, Atharva Rajesh Chavan, Mandeep Chahal, Rajeev Taliyan
The use of chemiluminophores for tracing enzymatic activities in live-cell imaging has gained significant attention, making them valuable tools for diagnostic applications. Among various chemiluminophores, the phenoxy-1,2-dioxetane scaffold exhibits significant...
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Analyst, 2024, 149,5372-5380
DOI: 10.1039/D4AN00861H, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Felix Frank, Daniela Tomasetig, Peter Nahringbauer, Wolfgang Ipsmiller, Gerd Mauschitz, Karin Wieland, Bernhard Lendl
Coupling Raman and VIS spectroscopy enables the study of AgNP aggregations induced by surfactants.
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Analyst, 2024, 149,5455-5462
DOI: 10.1039/D4AN00965G, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Hao Zhou, Weixiong Zhao, Weihua Cui, Bingxuan Lv, Bo Fang, Nana Yang, Guangfeng Xiang, Weijun Zhang, Lunhua Deng, Weidong Chen
A simple five-parameters spectrogram model for the VIPA spectrometer frequency calibration is developed, which has the advantages of high accuracy, simple setup and easy-to-solve.
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Analyst, 2024, 149,5443-5454
DOI: 10.1039/D4AN00956H, Paper

Patrycja Leszczenko, Anna M. Nowakowska, Patrycja Dawiec, Karolina Czuja, Justyna Jakubowska, Marta Zabczynska, Agata Pastorczak, Kinga Ostrowska, Szymon Tott, Wojciech Mlynarski, Malgorzata Baranska, Katarzyna Majzner
Acute lymphoblastic leukaemia (ALL) is a complex disease in pediatric oncology, necessitating accurate diagnostic strategies for effective treatment planning.
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Analyst, 2024, 149,5381-5393
DOI: 10.1039/D4AN00868E, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Edoardo Farnesi, Matteo Calvarese, Chen Liu, Carl Messerschmidt, MohammadSadegh Vafaeinezhad, Tobias Meyer-Zedler, Dana Cialla-May, Christoph Krafft, Jonas Ballmaier, Orlando Guntinas-Lichius, Michael Schmitt, Jürgen Popp
The study demonstrates the potential of advanced vibrational spectroscopy to reveal the complex molecular composition of cerumen, suggesting its promising application as a non-invasive diagnostic tool for identifying disease-related biomarkers.
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Analyst, 2024, 149,5401-5410
DOI: 10.1039/D4AN00990H, Paper

Nor Dyana Zakaria, Ibrahim Luqman Salih, Hairul Hisham Hamzah, Turgut Sönmez, Muhamad Huzaifah Omar, Noorhashimah Mohamad Nor, Khairunisak Abdul Razak, Venugopal Balakrishnan
The graphic abstract displays the integration of the SPGE measurement system with an electrochemical cell-based 3D printing to evaluate the electrochemical behaviors and 3D images of both unactivated and activated SPGEs.
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Analyst, 2024, 149,5504-5517
DOI: 10.1039/D4AN01142B, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Enoch Amoah, Taghi Sahraeian, Ayesha Seth, Abraham K. Badu-Tawiah
Halide adduction enables the generation of diagnostic fragments ions for oligosaccharide isomers enabling multi-dimensional mass spectrometry analysis without prior separation.
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Analyst, 2024, 149,5482-5490
DOI: 10.1039/D4AN01186D, Paper

Jin Wang, Xiangmei Li, Hongtao Lei, Juewen Liu
Using capture-SELEX, short aptamers for metronidazole and ibuprofen were isolated and they can be used for the detection of these drugs illicitly added to soft drinks.
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Analyst, 2024, 149,5394-5400
DOI: 10.1039/D4AN01060D, Paper

Xiaoqing Zhang, Shanglin Li, Mei Liu
A fluorescence biosensing strategy was developed based on CuS-BSA for sensitive and rapid detection of Escherichia coli.
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Analyst, 2024, 149,5527-5534
DOI: 10.1039/D4AN01107D, Paper

Hongliang Ma, Shiqi Wang, Gaoxuan Wang, Qilei Zhang, Shenlong Zha, Xueyuan Cai, Lingli Li, Pan Pan, Qiang Liu, Shengbao Zhan
A novel method combining dual-channel concentration signal averaging with detector gain optimization is proposed to improve the measurement precision and response speed of the sensor within the 1–10 second integration time.
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Analyst, 2024, 149,5555-5562
DOI: 10.1039/D4AN01075B, Paper

Nikita Thomas, Mengzhen Lyu, Jadon Khouv, Dhésmon Lima, Sabine Kuss
The cellular electrochemical current response is impacted by media composition and light exposure during scanning electrochemical microscopy (SECM).
The content of this RSS Feed (c) The Royal Society of Chemistry

Analyst, 2024, 149,5463-5475
DOI: 10.1039/D4AN01044B, Paper

Zuriel Erikson Joven, Piyush Raj, Ishan Barman
Monte Carlo simulations of spatially offset Raman spectroscopy (SORS) produce widely-applicable, quantitative frameworks for optimizing and interpreting SORS experiments.
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Analyst, 2024, 149,5433-5442
DOI: 10.1039/D4AN00787E, Paper

Qi Wang, Pei Liu, Ke Xiao, Wenying Zhou, Jinfeng Li, Yun Xi
Group A streptococcus (GAS) is a pathogen typically transmitted through respiratory droplets and skin contact, causing an estimated 700 million mild non-invasive infections worldwide each year.
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Analyst, 2024, 149,5491-5503
DOI: 10.1039/D4AN00866A, Paper

Vandana Kuttappan Nair, Chandrika Sharma, Shrawan Kumar, Mrittika Sengupta, Souradyuti Ghosh
Comprehensive quantitative analysis of various ligation and digestion conditions to identify and minimize non-specific amplification in RCA bioanalytical methods.
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Analyst, 2024, 149,5563-5571
DOI: 10.1039/D4AN01127A, Paper

Zhentao Sun, Youquan Zhao, Yameng Liu, Chen Chen, Hao Chen
A paper-based microfluidic disc is used for the rapid determination of various nutrients in water.
The content of this RSS Feed (c) The Royal Society of Chemistry

Analyst, 2024, 149,5518-5526
DOI: 10.1039/D4AN01139B, Paper

Tapparath Leelasattarathkul, Thithawat Trakoolwilaiwan, Kawin Khachornsakkul
A simple and low-cost distance-based paper analytical device (dPAD) was combined with gold nanomaterials for uric acid quantification.
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Analyst, 2024, 149,5546-5554
DOI: 10.1039/D4AN01096E, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Ruchi Gupta, Nicholas J. Goddard
In this work, acoustically levitated droplets serve as wells of microtitre plates and are acoustically manipulated to perform chemical and biological reactions in a non-contact fashion.
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Analyst, 2024, 149,5535-5545
DOI: 10.1039/D4AN00729H, Paper

Open Access

  This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Katherine J. I. Ember, Nassim Ksantini, Frédérick Dallaire, Guillaume Sheehy, Trang Tran, Mathieu Dehaes, Madeleine Durand, Dominique Trudel, Frédéric Leblond
Raman spectroscopy and machine learning is used in combination to detect COVID-19 positive saliva in liquid form.
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Analyst, 2024, Accepted Manuscript
DOI: 10.1039/D4AN01297F, Paper

Adrian Ebenazer Paul, Gaurav Gaur, Abdullah Alswieleh, Jerry J. Wu, Sambandam Anandan
The concentration of sodium ions can cause severe imbalances (high pressure on blood vessels, swelling of the muscular tissues, and misfunctioning of the whole nervous system) to the system in...
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00784K, Paper

Liang Ma, Wenqing Gao, Xiangyang Hu, Dongdong Zhou, Chenlu Wang, Jiancheng Yu, Keqi Tang
An improved cancer diagnosis algorithm for protein mass spectrometry based on PCA and 1D neural network combining ResNet and SENet is proposed and successfully applied to the diagnosis of ovarian cancer with high accuracy and strong fitting ability.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01112K, Paper

Johan Yi, Suyeon Kim, Chungmin Han, Jaesung Park
A TIRF microscopy-based method for single vesicle aggregation analysis enables precise assessment of EV aggregation under various conditions, enhancing EV characterization and functional analysis.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01103A, Critical Review

Wenteng Tang, Junlei Han, Wenhong Zhang, Huimin Li, Jun Chen, Wei Song, Li Wang
Molecularly imprinted polymer sensors, combined with electrochemical, optical, thermal, and acoustic detection technologies, detect biomarkers for key cardiovascular diseases: coronary artery disease, acute myocardial infarction, and heart failure.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01260G, Paper

Sunil S. Adav, Yan Wen Crystal Tan, Choon Teck Low, Song Wei Loo, Ridhwan Yusoff, Archana Gautam, Yuk Lin Yong, Chiew Yung Yang, Chin Chin Lim, Kee Woei Ng
In firearm forensic investigations, detecting gunshot residue (GSR) is crucial for linking firearms to suspects and determining firing distance for forensic reconstruction.
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Analyst, 2024, Accepted Manuscript
DOI: 10.1039/D4AN01095G, Paper

Jiafan Ji, Qianqian Yan, Yi Chen, Gaosheng Zhao, Bin Jia, Li Xu, Ping Cheng
Ground-level ozone pollution poses significant risks to both ecosystems and human health, necessitating the implementation of effective control strategies. This investigtion concentrated on a monolithic ozone degradation catalyst composed of...
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01175A, Minireview

Chenyang Xu, Huanhuan Shi, Zhongjian Tan, Yun Zheng, Weizheng Xu, Zhengxian Dan, Jiacong Liao, Zhiying Dai, Yali Zhao
This review discusses the formation and manipulation of magnetic droplets on microfluidic chips and classifies related detection techniques. Applications in biomedicine were reviewed. Future development of this emerging field is provided.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00872C, Paper

Chia Yen Liew, Wun-Long Li, Chi-Kung Ni
Logical procedures for structural determination of fructooligosaccharides and raffinose family oligosaccharides.
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Analyst, 2024, Accepted Manuscript
DOI: 10.1039/D4AN01305K, Paper

Yi-Xuan Li, Yu-Xuan Dai, Ju-Zheng Wang, Jérôme Chauvin, Xueji Zhang, Serge Cosnier, Robert Marks, Dan Shan
The concentration of zinc ions in semen is significantly correlated to the sperm viability and male fertility. In this work, a reliable ratiometric fluorescence probe (ZIF-9-TCPP) based on the efficient...
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Analyst, 2024, Accepted Manuscript
DOI: 10.1039/D4AN01269K, Paper

Hong Zeng, Xiao Ma, Shufen Pan, Yuting Han, Yanyan Tang, Yulan Fan, Yongquan Wu
Inflammation is a complex physiological response involving various cellular and molecular events. Sulfur dioxide (SO2), which is usually in the form of HSO3- and SO32- under physiological conditions, plays a...
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01164C, Paper

Anil Sharma, Thomas Hulse, Aymen H. Qatamin, Monica Moreno, Klester S. Souza, Marcelo B. Pereira, Fabricio S. Campos, Leandro B. Carneiro, Antonio M. H. de Andrade, Paulo M. Roehe, Flavio Horowitz, Sergio B. Mendes
This article focuses on the application of electrochemically modulated surface plasmon waves for structural characterization and for assessing signal transduction performance of redox-labeled DNA-based sensing platforms.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01029A, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Md Raduanul H. Chowdhury, Clementinah Oladun, Nuwandi M. Ariyasingha, Anna Samoilenko, Tarek Bawardi, Dudari B. Burueva, Oleg G. Salnikov, Larisa M. Kovtunova, Valerii I. Bukhtiyarov, Zhongjie Shi, Kehuan Luo, Sidhartha Tan, Juri G. Gelovani, Igor V. Koptyug, Boyd M. Goodson, Eduard Y. Chekmenev
The feasibility of ultrafast (1.7 s) ventilation MRI with a 1 × 1 × 50 mm³ voxel size is demonstrated using hyperpolarized propane gas contrast agent in excised rabbit lungs on a 0.35 T clinical MRI scanner without any scanner modification.
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Analyst, 2024, Advance Article
DOI: 10.1039/D4AN01054J, Paper

Open Access

  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Eirini Malegiannaki, Pascal Bohleber, Daniele Zannoni, Ciprian Stremtan, Agnese Petteni, Barbara Stenni, Carlo Barbante, Bo M. Vinther, Vasileios Gkinis
A new micro-destructive technique for high-resolution water isotope analysis of ice samples using a Laser Ablation (LA) system coupled with a Cavity Ring Down Spectrometer (CRDS) is presented.
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