Interview with Diana W. Bianchi, MD, author of Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies

Interview with Thomas A. Gaziano, MD, MSc, author of Cost-effectiveness of 10-Year Risk Thresholds for Initiation of Statin Therapy for Primary Prevention of Cardiovascular Disease

Interview with Carolina Malta Hansen, MD, author of Association of Bystander and First-Responder Intervention With Survival After Out-of-Hospital Cardiac Arrest in North Carolina, 2010-2013

Interview with Harlan M. Krumholz, MD, SM, author of Mortality, Hospitalizations, and Expenditures for the Medicare Population Aged 65 Years or Older, 1999-2013

Medicare at 50: Reflections From Former CMS Administrator Donald M. Berwick, MD

Interview with Drew Altman, PhD and William Frist, MD, authors of Medicare and Medicaid at 50 Years: Perspectives of Beneficiaries, Health Care Professionals and Institutions, and Policy Makers

Interview with Melissa A. Polusny, PhD, author of Mindfulness-Based Stress Reduction for Posttraumatic Stress Disorder Among Veterans: A Randomized Clinical Trial

Edward H. Livingston, MD, interviews a war veteran and discusses PTSD with Maria Steenkamp, PhD, author of Psychotherapy for Military-Related PTSD, and Michele Spoont, PhD, author of Rational Clinical Exam: Does This Patient Have Posttraumatic Stress Disorder? The article by Dr Steenkamp reports that many military personnel and veterans with posttraumatic stress disorder achieve clinically meaningful improvement with use of the first-line trauma-focused interventions cognitive processing therapy and prolonged exposure.
 The Rational Clinical Examination Systematic Review by Dr Spoont examines the utility of self-report screening instruments for posttraumatic stress disorder among primary care and high-risk populations.

Interview with Shalender Bhasin, MBBS, author of Effects of Testosterone Administration for 3 Years on Subclinical Atherosclerosis Progression in Older Men With Low or Low-Normal Testosterone Levels: A Randomized Clinical Trial

Interview with Rachel E. Patzer, PhD, MPH, author of Variation in Dialysis Facility Referral for Kidney Transplantation Among Patients With End-Stage Renal Disease in Georgia. This population epidemiology study uses United States Renal Data System data to characterize dialysis facility–level referral for kidney transplant evaluation in Georgia, the US state with the lowest transplantation rates, and patient and facility factors associated with referral and waitlisting.

Interview with Adam M. Leventhal, PhD, author of Association of Electronic Cigarette Use With Initiation of Combustible Tobacco Product Smoking in Early Adolescence

Interview with Nancy A. Rigotti, MD, author of e-Cigarette Use and Subsequent Tobacco Use by Adolescents: New Evidence About a Potential Risk of e-Cigarettes

Interview with Kaycee M. Sink, MD, MAS, author of Effect of a 24-Month Physical Activity Intervention vs Health Education on Cognitive Outcomes in Sedentary Older Adults: The LIFE Randomized Trial

Interview with Timothy Ley, MD, author of Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia

Interview with Bridget A. Fernandez, MD, author of Molecular Diagnostic Yield of Chromosomal Microarray Analysis and Whole-Exome Sequencing in Children With Autism Spectrum Disorder

Interview with Luke Rudmik, MD, MSc, author of Medical Therapies for Adult Chronic Sinusitis: A Systematic Review. This systematic review summarizes the evidence-based medical treatment of adult chronic sinusitis and proposes a treatment algorithm.

Interview with Andy Menke, PhD, author of Prevalence of and Trends in Diabetes Among Adults in the United States, 1988-2012

Interview with Anupam Jena, MD, PhD, author of Sex Differences in Academic Rank in US Medical Schools in 2014

Adi Nadimpalli, MD, the Doctors Without Borders/Médecins Sans Frontières (MSF) Head of Mission in Nepal, and the former vice president of the US board of directors, talks about MSF’s mission and the challenges he has faced serving in countries where access to health care is insufficient or strained due to natural or manmade disasters, violent conflicts, epidemics, and population displacement.

Interview with Timothy Fendler, MD, MS, author of Alignment of Do-Not-Resuscitate Status With Patients’ Likelihood of Favorable Neurological Survival After In-Hospital Cardiac Arrest

Interview with Carlos G. Grijalva, MD, MPH, author of Association Between Hospitalization With Community-Acquired Laboratory-Confirmed Influenza Pneumonia and Prior Receipt of Influenza Vaccination

Interview with James Fleshman, MD, author of Effect of Laparoscopic-Assisted Resection vs Open Resection of Stage II or III Rectal Cancer on Pathologic Outcomes: The ACOSOG Z6051 Randomized Clinical Trial

Interview with Kevin C. Oeffinger, MD, author of Breast Cancer Screening for Women at Average Risk: 2015 Guideline Update From the American Cancer Society

Interview with Elizabeth T. H. Fontham, MPH, DrPH, author of Breast Cancer Screening for Women at Average Risk: 2015 Guideline Update From the American Cancer Society, Nancy L. Keating, MD, MPH, author of New Guidelines for Breast Cancer Screening in US Women, and Evan R. Myers, MD, MPH, author of Benefits and Harms of Breast Cancer Screening: A Systematic Review

Interview with Elizabeth D. Kantor, PhD, MPH, author of Trends in Prescription Drug Use Among Adults in the United States From 1999-2012

Interview with David A. Asch, MD and Kevin G. Volpp, MD, PhD, authors of Effect of Financial Incentives to Physicians, Patients, or Both on Lipid Levels: A Randomized Clinical Trial

Interview with David Simel, MD, author of Does This Patient With Chest Pain Have Acute Coronary Syndrome? The Rational Clinical Examination Systematic Review

ACS is a common and potentially lethal problem. However, only about 10% of patients who present to an emergency department with chest pain actually have ACS. In this JAMA Clinical Reviews podcast, we discuss which signs, symptoms and tests used to make the diagnosis of ACS are reliable.

Edward H. Livingston MD, speaks with Alexander Fanaroff, MD, author of Does This Patient With Chest Pain Have Acute Coronary Syndrome? The Rational Clinical Examination Systematic Review as well as a patient who was diagnosed with myocardial infarction.

Interview with Lee M. Jampol, MD, author of Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy: A Randomized Clinical Trial

Interview with Leonard B. Bacharier, MD, author of Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial

Edward H. Livingston, MD, Deputy Editor of Clinical Reviews and Education and Jon Tilburt, MD, from the Mayo Clinic explain prostate cancer screening. For more information, read the JAMA Patient Page on this topic.

Edward H. Livingston, MD, Deputy Editor of Clinical Reviews and Education discusses prostate cancer screening with Otis Brawley, MD, author of Prostate Cancer Incidence and PSA Testing Patterns in Relation to USPSTF Screening Recommendations and David F. Penson, MD, MPH, author of a related editorial entitled The Pendulum of Prostate Cancer Screening.

Edward H. Livingston MD, explores the topic of prostate cancer screening in author interviews with:

• Dan Merenstein about losing a malpractice case despite following evidence-based medicine guidelines (PSA Screening — I Finally Won!).
• Otis Brawley about Prostate Cancer Incidence and PSA Testing Patterns in Relation to USPSTF Screening Recommendations.
• David F. Penson about The Pendulum of Prostate Cancer Screening.
• Victor M. Montori about The Connection Between Evidence-Based Medicine and Shared Decision Making.

Interview with Alex B. Haynes, MD, MPH, author of Relationship Between Cesarean Delivery Rate and Maternal and Neonatal Mortality

Interview with Ingrid M. Libman, MD, PhD, author of Effect of Metformin Added to Insulin on Glycemic Control Among Overweight/Obese Adolescents With Type 1 Diabetes

Interview with Thomas L. Schwenk, MD, author of Resident Depression: The Tip of a Graduate Medical Education Iceberg

Interview with Roger Stupp, MD, author of Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial

Interview with John H. Sampson, MD, PhD, MHSc, MBA, author of Alternating Electric Fields for the Treatment of Glioblastoma

Interview with Dalane W. Kitzman, MD, author of Effect of Caloric Restriction or Aerobic Exercise Training on Peak Oxygen Consumption and Quality of Life in Obese Older Patients With Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial

Interview with Gaëtan Deslée, MD, PhD, author of Lung Volume Reduction Coil Treatment vs Usual Care in Patients With Severe Emphysema: The REVOLENS Randomized Clinical Trial

Constipation is one of the most frequent problems clinicians are asked to deal with. Despite how common it is, constipation is frequently not treated adequately. In this podcast, Arnold Wald, MD, explains a stepwise approach to the management of constipation ranging from very simple measures to the most novel and complicated new medical therapies.

Interview with Justin E. Bekelman, MD, author of Comparison of Site of Death, Health Care Utilization, and Hospital Expenditures for Patients Dying With Cancer in 7 Developed Countries

Interview with Michael P. Pignone, MD, MPH, author of Screening for Depression in Adults: US Preventive Services Task Force Recommendation Statement

Interview with Martha Clare Morris, ScD, author of Association of Seafood Consumption, Brain Mercury Level, and APOE ε4 Status With Brain Neuropathology in Older Adults

Community acquired pneumonia accounts for 600,000 hospital admissions a year. Many patients with this disease are quite ill and have a very high mortality. To save lives, the appropriate antibiotics should be given in a timely basis, but it is not clear what the best antibiotics are and how long they should be given. In this podcast we interview the author of a JAMA review on community acquired pneumonia, Dr Jonathan Lee, author of Antibiotic Therapy for Adults Hospitalized With Community-Acquired Pneumonia, who performed a systematic review of the literature to determine the best way to treat community acquired pneumonia.

Interview with David C. Grossman, MD, MPH, author of Screening for Autism Spectrum Disorder in Young Children: US Preventive Services Task Force Recommendation Statement

Interview with John G. Laffey, MD, MA, author of Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries

Interview with Clifford Deutschman, MD, MS, Mervyn Singer, MD and Derek Angus, MD, MPH, authors of The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

Interview with Michael P. Pignone, MD, MPH, author of Screening for Impaired Visual Acuity in Older Adults: US Preventive Services Task Force Recommendation Statement

Interview with Lynn Babcock, MD, MS, author of Identifying Children and Adolescents at Risk for Persistent Postconcussion Symptoms