at Palmitoylation of acetylated tubulin and association with ceramide-rich platforms is critical for ciliogenesis By www.jlr.org Published On :: 2020-12-30 Priyanka TripathiDec 30, 2020; 0:jlr.RA120001190v1-jlr.RA120001190Research Articles Full Article
at Nuclear translocation ability of Lipin differentially affects gene expression and survival in fed and fasting Drosophila By www.jlr.org Published On :: 2020-12-01 Stephanie E. HoodDec 1, 2020; 61:1720-1732Research Articles Full Article
at Sterol regulatory element-binding protein Sre1 regulates carotenogenesis in the red yeast Xanthophyllomyces dendrorhous By www.jlr.org Published On :: 2020-12-01 Melissa GómezDec 1, 2020; 61:1658-1674Research Articles Full Article
at Hsa-miRNA-23a-3p promotes atherogenesis in a novel mouse model of atherosclerosis By www.jlr.org Published On :: 2020-12-01 Jiayan GuoDec 1, 2020; 61:1764-1775Research Articles Full Article
at Stimulation of ABCB4/MDR3 ATPase activity requires an intact phosphatidylcholine lipid By www.jlr.org Published On :: 2020-12-01 Martin PrescherDec 1, 2020; 61:1605-1616Research Articles Full Article
at Progression of chronic kidney disease in familial LCAT deficiency: a follow-up of the Italian cohort By www.jlr.org Published On :: 2020-12-01 Chiara PavanelloDec 1, 2020; 61:1784-1788Patient-Oriented and Epidemiological Research Full Article
at Bioavailability and spatial distribution of fatty acids in the rat retina after dietary omega-3 supplementation By www.jlr.org Published On :: 2020-12-01 Elisa VidalDec 1, 2020; 61:1733-1746Research Articles Full Article
at Gene Networks and Pathways for Plasma Lipid Traits via Multi-tissue Multi-omics Systems Analysis By www.jlr.org Published On :: 2020-12-23 Montgomery BlencoweDec 23, 2020; 0:jlr.RA120000713v1-jlr.RA120000713Research Articles Full Article
at A review of phosphatidate phosphatase assays By www.jlr.org Published On :: 2020-12-01 Prabuddha DeyDec 1, 2020; 61:1556-1564Reviews Full Article
at Human glucocerebrosidase mediates formation of xylosyl-cholesterol by {beta}-xylosidase and transxylosidase reactions. By www.jlr.org Published On :: 2020-12-23 Daphne E.C. BoerDec 23, 2020; 0:jlr.RA120001043v1-jlr.RA120001043Research Articles Full Article
at Spatial profiling of gangliosides in mouse brain by mass spectrometry imaging By www.jlr.org Published On :: 2020-12-01 Douglas A. AndresDec 1, 2020; 61:1537-1537Images in Lipid Research Full Article
at Myeloid deletion and therapeutic activation of AMPK do not alter atherosclerosis in male or female mice By www.jlr.org Published On :: 2020-12-01 Nicholas D. LeBlondDec 1, 2020; 61:1697-1706Research Articles Full Article
at LDL apheresis as an alternate method for plasma LPS purification in healthy volunteers and dyslipidemic and septic patients By www.jlr.org Published On :: 2020-12-01 Auguste DargentDec 1, 2020; 61:1776-1783Research Articles Full Article
at Lipid signature of advanced human carotid atherosclerosis assessed by mass spectrometry imaging By www.jlr.org Published On :: 2020-12-23 Astrid M. MoermanDec 23, 2020; 0:jlr.RA120000974v1-jlr.RA120000974Research Articles Full Article
at Insulin resistance dysregulates CYP7B1 leading to oxysterol accumulation: a pathway for NAFL to NASH transition By www.jlr.org Published On :: 2020-12-01 Genta KakiyamaDec 1, 2020; 61:1629-1644Research Articles Full Article
at The anti-tubercular activity of simvastatin is mediated by cholesterol-driven autophagy via the AMPK-mTORC1-TFEB axis By www.jlr.org Published On :: 2020-12-01 Natalie BruinersDec 1, 2020; 61:1617-1628Research Articles Full Article
at Identification of unusual phospholipids from bovine heart mitochondria by HPLC-MS/MS By www.jlr.org Published On :: 2020-12-01 Junhwan KimDec 1, 2020; 61:1707-1719Research Articles Full Article
at Deletion of lysophosphatidylcholine acyltransferase3 in myeloid cells worsens hepatic steatosis after a high fat diet By www.jlr.org Published On :: 2020-12-11 Thibaut BourgeoisDec 11, 2020; 0:jlr.RA120000737v1-jlr.RA120000737Research Articles Full Article
at Lipid metabolism dysregulation in diabetic retinopathy By www.jlr.org Published On :: 2020-12-23 Julia V BusikDec 23, 2020; 0:jlr.TR120000981v1-jlr.TR120000981Thematic Reviews Full Article
at Human CETP lacks lipopolysaccharide transfer activity, but worsens inflammation and sepsis outcomes in mice By www.jlr.org Published On :: 2020-12-09 Aloïs DusuelDec 9, 2020; 0:jlr.RA120000704v1-jlr.RA120000704Research Articles Full Article
at Mutation in the distal NPxY motif of LRP1 alleviates dietary cholesterol-induced dyslipidemia and tissue inflammation By www.jlr.org Published On :: 2020-12-09 Anja JaeschkeDec 9, 2020; 0:jlr.RA120001141v1-jlr.RA120001141Research Articles Full Article
at Membrane-bound sn-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice By www.jlr.org Published On :: 2020-12-01 Abudukadier AbuliziDec 1, 2020; 61:1565-1576Research Articles Full Article
at SCD1 promotes lipid mobilization in subcutaneous white adipose tissue By www.jlr.org Published On :: 2020-12-01 Ying ZouDec 1, 2020; 61:1589-1604Research Articles Full Article
at Structure dynamics of ApoA-I amyloidogenic variants in small HDL increase their ability to mediate cholesterol efflux By www.jlr.org Published On :: 2020-11-17 Oktawia NilssonNov 17, 2020; 0:jlr.RA120000920v1-jlr.RA120000920Research Articles Full Article
at rHDL modelling and the anchoring mechanism of LCAT activation By www.jlr.org Published On :: 2020-12-02 Tommaso LaurenziDec 2, 2020; 0:jlr.RA120000843v1-jlr.RA120000843Research Articles Full Article
at Apolipoprotein C3 and apolipoprotein B colocalize in proximity to macrophages in atherosclerotic lesions in diabetes By www.jlr.org Published On :: 2020-12-08 Jenny E. KanterDec 8, 2020; 0:jlr.ILR120001217v1-jlr.ILR120001217Images in Lipid Research Full Article
at Distinct patterns of apolipoprotein C-I, C-II and C-III isoforms are associated with markers of Alzheimers disease By www.jlr.org Published On :: 2020-12-11 Yueming HuDec 11, 2020; 0:jlr.RA120000919v1-jlr.RA120000919Research Articles Full Article
at Generation and validation of a conditional knockout mouse model for the study of the Smith-Lemli-Opitz Syndrome By www.jlr.org Published On :: 2020-11-17 Babunageswararao KanuriNov 17, 2020; 0:jlr.RA120001101v1-jlr.RA120001101Research Articles Full Article
at Perilipin 5 S155 phosphorylation by PKA is required for the control of hepatic lipid metabolism and glycemic control By www.jlr.org Published On :: 2020-12-17 Stacey N KeenanDec 17, 2020; 0:jlr.RA120001126v1-jlr.RA120001126Research Articles Full Article
at Adiponectin forms a complex with atherogenic LDL and inhibits its downstream effects By www.jlr.org Published On :: 2020-11-03 Akemi KakinoNov 3, 2020; 0:jlr.RA120000767v1-jlr.RA120000767Research Articles Full Article
at Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures By www.jlr.org Published On :: 2020-12-01 Gerhard LiebischDec 1, 2020; 61:1539-1555Special Report Full Article
at Mass spectrometry characterization of light chain fragmentation sites in cardiac AL amyloidosis: insights into the timing of proteolysis [Genomics and Proteomics] By www.jbc.org Published On :: 2020-12-04T00:06:05-08:00 Amyloid fibrils are polymeric structures originating from aggregation of misfolded proteins. In vivo, proteolysis may modulate amyloidogenesis and fibril stability. In light chain (AL) amyloidosis, fragmented light chains (LCs) are abundant components of amyloid deposits; however, site and timing of proteolysis are debated. Identification of the N and C termini of LC fragments is instrumental to understanding involved processes and enzymes. We investigated the N and C terminome of the LC proteoforms in fibrils extracted from the hearts of two AL cardiomyopathy patients, using a proteomic approach based on derivatization of N- and C-terminal residues, followed by mapping of fragmentation sites on the structures of native and fibrillar relevant LCs. We provide the first high-specificity map of proteolytic cleavages in natural AL amyloid. Proteolysis occurs both on the LC variable and constant domains, generating a complex fragmentation pattern. The structural analysis indicates extensive remodeling by multiple proteases, largely taking place on poorly folded regions of the fibril surfaces. This study adds novel important knowledge on amyloid LC processing: although our data do not exclude that proteolysis of native LC dimers may destabilize their structure and favor fibril formation, the data show that LC deposition largely precedes the proteolytic events documentable in mature AL fibrils. Full Article
at Problem Notes for SAS®9 - 66438: You see the message "The informat $ could not be loaded, probably due to insufficient memory" after attempting to insert data into a MySQL database By Published On :: Wed, 2 Sep 2020 10:39:14 EST For data that is being loaded from a SAS Stored Process Server, an insertion process might fail to a MySQL database with a warning, as well as an error message that says "During insert: Incorrect datetime value " Full Article BASE+Base+SAS
at Problem Notes for SAS®9 - 66537: SAS Customer Intelligence Studio becomes non-responsive when you delete a calculated variable from the Edit Value dialog box By Published On :: Tue, 1 Sep 2020 14:25:38 EST In SAS Customer Intelligence Studio, you might notice that the user interface becomes unresponsive, as shown below: imgalt="SAS Customer Intelligence Studio UI becomes unresponsive" src="{fusion_66537 Full Article CAMPAIGNSDO+SAS+Customer+Intelligence+St
at Problem Notes for SAS®9 - 66539: A new calculated variable that you create in the Edit Value dialog box is not available for selection in SAS Customer Intelligence Studio By Published On :: Tue, 1 Sep 2020 13:44:23 EST In SAS Customer Intelligence Studio, you can choose to create a new calculated variable in the Edit Value dialog box when you populate a treatment custom detail. Following creation of the new calculated Full Article CAMPAIGNSDO+SAS+Customer+Intelligence+St
at Problem Notes for SAS®9 - 66527: Updating counts in a Link node in SAS Customer Intelligence Studio produces the error "Link: MAIQService:executeFastPath:" By Published On :: Tue, 1 Sep 2020 10:53:01 EST In SAS Customer Intelligence Studio, the following error is displayed when you update a new Link node in a diagram: imgalt="Link: MAIQService:executeFastPath:" src="{fusion_665 Full Article CAMPAIGNSDO+SAS+Customer+Intelligence+St
at Problem Notes for SAS®9 - 66540: SAS Management Console and SAS Data Integration Studio might return the message "table failed to update" when you use the Update Metadata tool By Published On :: Tue, 1 Sep 2020 09:06:18 EST You encounter this issue when the table metadata matches the data source. In this scenario, no metadata update is required. Full Article MGMTCONSOLE+SAS+Management+Console
at Problem Notes for SAS®9 - 66524: SAS Visual Data Builder uses the wrong SAS Application Server for previewing and scheduling By Published On :: Mon, 31 Aug 2020 12:14:44 EST If you have configured more than one SAS Application Server, then SAS Visual Data Builder might unexpectedly use the wrong application server when you preview or schedule queries. This problem occurs even though you h Full Article VISANLYTBNDL+SAS+Visual+Analytics
at Problem Notes for SAS®9 - 66487: Authentication to the CAS server fails with the error "Access denied..." when initiated on a SAS/CONNECT server in a Microsoft Windows environment By Published On :: Mon, 31 Aug 2020 10:33:55 EST You might see the following error messages: "ERROR: Connection failed. Server returned: SAS Logon Manager authentication failed: Access denied." and "ERROR: Unable to connect to Cloud Analytic Services host-name on port 5570. Veri Full Article CONNECT+SAS/CONNECT
at Problem Notes for SAS®9 - 55516: Opening the Edit Action Columns dialog box requires that you wait up to a minute to display a window By Published On :: Fri, 28 Aug 2020 11:23:00 EST Editing and/or saving an action column can take up to a minute to display a window. There are no workarounds identified at this time. Full Article SCDOFR+SAS+Visual+Scenario+Designer
at Problem Notes for SAS®9 - 66509: Several procedures in SAS/STAT Software and SAS/QC Software generate incorrect results when an OBSMARGINS= data set is used By Published On :: Fri, 28 Aug 2020 08:58:34 EST If the response variable is in the CLASS statement variable list before the class variables that also appear in the MODEL statement, and an OM-data-set is used, least squares means results for several of the statistical procedures are incorrect. Full Article STAT+SAS/STAT
at Problem Notes for SAS®9 - 66391: Opening a database table returns a Segmentation Violation when you use the Metadata LIBNAME engine (META) By Published On :: Wed, 26 Aug 2020 16:39:25 EST You might receive a Segmentation Violation when opening a database table in SAS. The SAS Log contains the error and traceback: ERR Full Article METADATASRV+SAS+Metadata+Server
at Problem Notes for SAS®9 - 58465: SAS Life Science Analytics Framework 4.6 - Group membership removal fails with an exception for Process Flows that exist in the Recycle Bin By Published On :: Wed, 26 Aug 2020 16:27:10 EST In SAS Life Science Analytics Framework 4.6, group membership removal fails with an exception if a user is set as assignee, a candidate, or a notification recipient in a user task for a Process Flow . The Process Full Article LSAFOFR+SAS+Life+Science+Analytics+Frame
at Problem Notes for SAS®9 - 33449: An error might occur when you use SAS 9 BULKLOAD= and BULKEXTRACT= options to load data to or extract data from the HP Neoview database on the HP Itanium platform By Published On :: Wed, 26 Aug 2020 16:21:08 EST An error might occur when you use the SAS 9 BULKLOAD= and BULKEXTRACT= options load data to or extract data from HP Neoview on the HP Itanium platform. The problem occurs because Hewlett-Packard changed the name of one of Full Article NEOVIEW+SAS/ACCESS+Interface+to+HP+Neovi
at Problem Notes for SAS®9 - 48028: Custom Time Frame-based data versions do not aggregate correctly when referenced in worksheets with standard hierarchy levels By Published On :: Wed, 26 Aug 2020 16:17:42 EST In SAS Merchandise Financial Planning, custom time frame-based data versions do not aggregate correctly when referenced in worksheets with standard hierarchy levels. The data does not aggregate correctly from l Full Article MMFINANCPLN+SAS+Merchandise+Financial+Pl
at Problem Notes for SAS®9 - 46544: Store layout view has some areas displayed with black fill rather than gray in SAS® Retail Space Management By Published On :: Wed, 26 Aug 2020 16:14:45 EST In SAS Retail Space Management, it should be possible to click on any location object, then Show Properties, and change the location fill color. This can be done on the gray-filled objects. However, w Full Article RTLSPCMGT+SAS+Retail+Space+Management
at Problem Notes for SAS®9 - 65782: The PLM procedure incorrectly issues the message "ERROR: No valid observation in the OM= data set" By Published On :: Wed, 26 Aug 2020 15:11:09 EST If the OBSMARGINS= or OM= option is specified in an LSMEANS, LSMESTIMATE, or SLICE statement and a user-defined format is applied to any of the effect variables in the OM-data-set , PROC PLM incorrectly stops proce Full Article STAT+SAS/STAT
at Problem Notes for SAS®9 - 66505: The OBS= option does not generate a limit clause when you use SAS/ACCESS Interface to PostgreSQL to access a Yellowbrick database By Published On :: Wed, 26 Aug 2020 11:35:41 EST When you use SAS/ACCESS Interface to PostgreSQL to query a Yellowbrick database, the SAS OBS= option is not generating a limit clause on the query that is passed to the database. Click the Full Article POSTGRESOFR+SAS/ACCESS+Interface+to+Post
at Problem Notes for SAS®9 - 66511: A Russian translation shows the same value for two different variables in the Define Value dialog box for the Reply node in SAS Customer Intelligence Studio By Published On :: Mon, 24 Aug 2020 14:23:55 EST In SAS Customer Intelligence Studio, when you add Reply- node variable values in the Define Value dialog box, you might notice that two identically labeled data-grid variables are Full Article POLICYOFR+SAS+Real-Time+Decision+Manager
at Problem Notes for SAS®9 - 66401: Using SAS Model Manager to publish a model to SAS Metadata Repository fails and generates an error By Published On :: Fri, 21 Aug 2020 09:34:11 EST When you publish a model to SAS Metadata Repository by using SAS Model Manager, the publishing process fails and the following error is generated: "The model model-name has a function of ';Transformation';, which is not supported for Full Article MMGROFR+SAS+Model+Manager
