for

Data storage device adjusting laser input power to compensate for temperature variations

A data storage device is disclosed comprising a head actuated over a disk, wherein the head comprises a laser configured to heat the disk while writing data to the disk. A temperature is measured, and a first input power is generated based on a first function of the measured temperature, wherein the first function compensates for a temperature dependent output power of the laser. A second input power is generated based on a second function of the measured temperature, wherein the second function compensates for a temperature dependent coercivity of the disk. The first input power is combined with the second input power to generate a write power applied to the laser while writing data to the disk.




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Thermally conductive features for a heat-assisted magnetic recording head

In a heat-assisted magnetic recording hard disk drive, one or more thermally conductive features are incorporated to assist with dissipation of heat from a laser module that comprises a laser and a submount. The submount may be coupled to the slider with solder covering a wider adhesive area for enhanced conduction of heat away from the laser module and to the slider, one or both of the submount and the laser may include a surface coating that increases the thermal radiation of the corresponding component, and/or one or both of the submount and the laser may include fins configured to transfer heat from the corresponding component. Further, a HAMR HGA may be configured such that the submount is coupled directly to the suspension flexure using a thermally conductive material, for conduction of heat away from the laser module and to the flexure.




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Optical information recording device and method

In an optical information recording device and optical information recording method for angularly multiplexing and recording data on pages on the same recording region on a hologram disk, data on each page is sequentially generated by sequentially dividing input data in predetermined units, the pages to be recorded on the same recording region are divided into page groups so that pages to be recorded adjacently by the angular multiplexing may not belong to the same group, each page group is individually subjected to inter-page coding processing for computing an error-correcting code and adding the computed error-correcting code, and data on the pages subjected to the inter-page coding processing is angularly multiplexed and recorded on the hologram disk.




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Optical disc with pre-recorded and recordable regions and method of forming the disc

An optical disc having a region with pre-recorded data and a recordable region, a method of fabricating the disc, a stamper for forming a disc master, and a recording device for use with the disc are disclosed. Data recorded in the recordable region may be used for activation of the disc, providing unique identification or enhancing program content on the disc.




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Method and apparatus for laser control during recording

The invention relates to recording on a medium, and in particular, to laser control during recording data on an optical medium. A laser control method for dynamically adjusting laser power during recording data onto an optical disc comprises: recording normal data onto the optical disc according to an initial laser power; stopping recording when a trigger is generated; reading back the recorded normal data and generating a first recording quality index; recording a test pattern at a test pattern starting point according to a selected laser power; reading back the test pattern and generating a second recording quality index; and determining an adaptive laser power to continually record the normal data according to the first recording quality index and the second recording quality index.




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Information storage medium, reproducing method, and recording method

A machine readable information storage medium, a reproducing method and apparatus which reproduces data from the storage medium, and a recording method and apparatus for recording data on the storage medium. The information storage medium includes a control area which stores within a data structure information usable by the recording or reproducing apparatus to record or reproduce the data on or from the storage medium. The information stored within the data structure includes a version corresponding to a specification.




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Hinge used for the treatment of anterior and posterior cruciate ligament injury and method for using the same

A device and method for using the device arranged to maintain anatomical alignment between a joint by creating a dynamic load around the joint to restore and maintain the anatomical alignment. The orthotic device uses a hinge to create a directed force on a tibia by maintaining misalignment of an instant center of rotation (ICoR) of the hinge at a position relative to an anatomical knee joint.




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Method and apparatus for monitoring surgical traction

Apparatus is described for measuring and displaying the magnitude of traction forces applied to a patient's lower limbs during surgery, and for measuring the direction and magnitude of counter-traction forces applied to the patient's body by the perineal post located at the patient's groin to oppose traction forces applied to the patient's lower limbs.




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Custom braces, casts and devices having fenestrations and methods for designing and fabricating

A custom brace and method for fabricating the custom brace includes marking a body with reference points and/or other indicators. Multiple images of the body from multiple angles are then obtained. The images are used to determine the contours of the body and the other markings are located and used to design the custom brace. Fenestrations can be added to the brace design. The custom brace can be fabricated with the fenestrations as a single piece structure or in multiple pieces that are assembled to complete the custom device.




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Force indicating attachment strap for an orthotic

An improved orthotic has a strap that secures the orthotic to a wearer, and comprises a tension indicator coupled to the strap. The tension indicator includes a first element disposed to produce a tactile signal when a tension in the strap reaches a threshold that is less than a permanent deformation threshold.




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Muscle training apparatus and belt for muscle training

To ensure easy and secure placement of a belt for KAATSU muscle training on a target compressed site near the proximal portion of a limb. A belt 100B has a longer first band-shaped member 110 and a shorter second band-shaped member 120 both of which have a band shape and are connected to a ring-shaped joint member 130 at their respective ends. In order to place the belt 100B on the target compressed site, the limb (right leg in this case) on which the belt 100B is expected to be placed is inserted into a loop of the first band-shaped member 110 formed by passing the end of the first band-shaped member 110 through an opening in the joint member 130, and the belt is moved up to the target compressed site. Then, the first band-shaped member 110 and the second band-shaped member 120 are pulled with both hands in the opposite directions. The belt 100B is placed on the target compressed site with the belt 100B being tensioned appropriately.




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Device and method for securing sutures and the like

A bandage and method for securing a tension member comprising a central body and a plurality of tabs disposed about the central body. A tension member may be disposed across or through a slit or aperture of the central body. A body adhesive on the lower surface of the central body may secure the bandage to the patient. The tension member may then be pulled across the upper surface of the central body and a first tab may be folded over and adhered to the tension member and central body. The tension member may then be pulled back across the first tab and a second tab may be folded over and adhered to the tension member and first tab. Likewise, the tension member may then be pulled back across the second tab and a third tab may be folded over and adhered to the tension member and second tab.




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Orthopedic device and method for correcting skeletal abnormalities in a new-born baby

An orthopedic device for correcting abnormalities in the wrist, hand, fingers and thumb of a newborn baby comprises a lightweight glove shaped semi rigid shell constructed and dimensioned to fit a newborn baby within a few hours of birth. A wrist or lower arm and hand engaging portion are rotatably connected and adjustable in one millimeter increments. The adjustments are made with no more than one millimeter correction per 24 hour period. The shell includes a wrist and lower forearm engaging portion, a hand engaging portion and a finger engaging portion and is adjustable for rotationally clockwise or counterclockwise about the longitudinal axis of the lower arm bone. Further adjustments may be made to rotate the fingers upwardly or downwardly, to the left or right and rotationally and/or rotational movement between the hand and lower arm. The invention also contemplates an orthopedic method for correcting skeletal abnormalities of the wrist, hand, fingers and thumb of a newborn baby.




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Extendible tourniquet cuff with stabilizer for improved utility and safety

A surgical tourniquet cuff that includes a stabilizer component that facilitates application of an overlapping cuff around the limb of a patient. The stabilizer is fixed to the cuff, and requires no tying or similar user manipulation to secure the overlapping cuff in alignment with the underlying cuff. The stabilizer improves the stability of the inflated cuff to prevent sideways shifting motion of overlapping cuff portions as the cuff is applied to the limb. The stabilizer also provides a handle mechanism to enable the user to snugly apply the overlapping cuff around the patient's limb while the overlapping portions remain properly aligned along their long axes. The stabilizer is designed to also facilitate attaching together two tourniquet cuffs end-to-end, with respective bladders overlapping and in proper alignment so that those attached cuffs can be used as a single, extended surgical cuff applied around a patient's limb.




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Bioadhesive for periodontal gingival and/or bone tissues

The invention is directed to an adhesive strip, particularly an adhesive strip or bandage for use in periodontal treatments. The biocompatible adhesive strip comprises a flexible barrier with a biocompatible adhesive for use in an oral environment, wherein the adhesive is in a non-tacky state when dry and becomes adherent upon contact with liquids.




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Bandage for facilitating transdermal respiration and healing

A bandage includes a reservoir filled with a perfluorochemical fluid, saturated with oxygen. Oxygen passes through a permeable membrane to the skin or wound to promote healing, and carbon dioxide travels from the skin or wound to the reservoir.




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Apparatus for detecting and treating ventricular arrhythmia

A system and method for long-term monitoring of cardiac conditions such as arrhythmias is disclosed. The invention includes a pulse generator including means for sensing an arrhythmia. The pulse generator is coupled to at least one subcutaneous electrode or electrode array for providing electrical stimulation such as cardioversion/defibrillation shocks and/or pacing pulses. The electrical stimulation may be provided between multiple subcutaneous electrodes, or between one or more such electrodes and the housing of the pulse generator. In one embodiment, the pulse generator includes one or more electrodes that are isolated from the can. These electrodes may be used to sense cardiac signals.




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Nasal septal splint and methods for using same

A splint for use in stabilizing the nasal septum of a subject following the completion of a septoplasty procedure has a longitudinal axis and is formed of a substantially rigid sheet having a longitudinal length, an anterior end, and a posterior end. The sheet is labeled with a plurality of guide markings that guide a user in shaping the splint prior to implantation of the splint within a nasal passage of the subject.




for

Method and apparatus for orthopedic cast removal utilizing a rotary impact driver

An orthopedic cast removal tool and method uses an unmodified, typically cordless, rotary impact driver and a embedded wire to cut through an orthopedic cast for removal. By merging it with a slotted spacer block specifically for this cast removal purpose, an ergonomic tool is provided which allays fears of orthopedic patients. When rotating and encountering high resistance of the plaster or fiberglass material of the cast, the cordless rotary impact driver does not bog down; since it seamlessly engages impact action, which offers an order of magnitude or more torque multiplication via short frequent pulses (several per second) to overcome this torque resistance. Thus a high amount of torque with very little reaction force is made available to cut through a cast while affording the technician good control. The cast is cut very rapidly with little dust creation and no jostling of the patient.




for

Knee orthosis, and method for controlling a knee orthosis

A knee orthosis and a method for controlling a knee orthosis including a thigh structure having a fastening structure to be fixed to a thigh, a lower leg structure which is pivotally coupled to the thigh rail using a joint mechanism and has a fastening structure to be fixed to a lower leg as well as a foot piece for supporting a foot, and an actuator device between the thigh structure and the lower leg structure. The fastening points of the actuator on the thigh structure and lower leg structure and the center of rotation of the joint mechanism form a triangle. The fastening points are arranged on the structures such that the connecting line between a fastening point and the center of rotation in an angular position of the knee in which the lower leg is bent at an angle ranging from 0° to 90° relative to the thigh.




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Device and method for control of hemorrhage

A junctional and truncal tourniquet and a hip-girdling pelvic sling device for maintaining a desired amount of tension surrounding a person's hips and pelvis to securely support and stabilize a pelvis that has been fractured and for securing a pressure applying device to a person so that blood vessel-occluding pressure can be applied. Areas of mating types of fastener material such as mating hook-bearing fastener material and loop pile fastener material are arranged on the device to enable a strap to be secured at various effective lengths to provide a wide range of adjustability. The device may include inflatable bladders, stays, and a chin support and may be wrapped around a patient's neck as a cervical support collar, or around the torso to occlude blood vessels proximal to an injury on a limb.




for

Fastening element, use of the element for immobilizing object, preferably parts of the body and device containing the element

The invention relates to a fixing element (33) extending as a flat, particularly lamellar element along a preferred direction (34) and comprising a corrugated sheet metal core (18) as a central component, said core providing the fixing element (33) with the characteristic of being integrally rigid and permanently deformable by hand, and said core being covered by a cover (36, 37). For such a fixing element, a large range of use is achieved in that the corrugations of the corrugated core sheet (18) are oriented substantially parallel to the preferred direction (34), and that means (38, 39) for releasably attaching the fixing element (33) are disposed on the fixing element (33).




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Method for restoring activity to a spent hydroprocessing catalyst, a spent hydroprocessing catalyst having restored catalytic activity, and a hyrdoprocessing process

A regenerated spent hydroprocessing catalyst treated with a chelating agent and having incorporated therein a polar additive.




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Catalyst for hydrogenation of oxalic ester to ethanol, method of preparing the catalyst, and method of using the same

A catalyst including: a support, the support including a mixture of SiO2 and ZrO2; an active ingredient including copper; a first additive including a metal, an oxide thereof, or a combination thereof; and a second additive including Li, Na, K, or a combination thereof. The metal is Mg, Ca, Ba, Mn, Fe, Co, Zn, Mo, La, or Ce. Based on the total weight of the catalyst, the weight percentages of the different components are as follows: SiO2=50-90 wt. %; ZrO2=0.1-10 wt. %; copper=10-50 wt. %; the first additive=0.1-10 wt. %; and the second additive=0.1-5 wt. %.




for

Component having a catalytic surface, method for the production thereof, and use of said component

A component part has a catalyst surface. This surface has metallic components and components of MnO2 (13) in contact with the former. The metallic components are preferably formed of Ag and/or Ni. These material pairs achieve a great improvement in catalyst action compared to the pure metals. Especially in the case of use of Ni, which is toxicologically safe, these surfaces, for example, may also find use in ambient air purification for reduction of the ozone content. The surface can be applied, for example, by a coating of the component part, in which case the metallic component and the component of MnO2 are applied in two layers.




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Catalyst for preparing carboxylic acids and/or carboxylic anhydrides

The present invention relates to a catalyst for preparing carboxylic acids and/or carboxylic anhydrides, which has a plurality of catalyst zones arranged in series and has been produced using a vanadium antimonate having a maximum content of crystalline valentinite of 5% by weight. The present invention further relates to a process for gas-phase oxidation in which a gas stream comprising at least one hydrocarbon and molecular oxygen is passed through a catalyst which has a plurality of catalyst zones arranged in series and has been produced using a vanadium antimonate having a maximum content of crystalline valentinite of 5% by weight.




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Composite of porous substrate and one-dimensional nanomaterial and method for preparing the same, surface-modified composite and method for preparing the same

The present invention relates to a composite of a porous substrate and one-dimensional nanomaterial, which is manufactured by a hydrothermal method. The method for manufacturing the composite of the present invention is simple and low-cost, and the one-dimensional nanomaterial is homogeneously distributed on the porous substrate with tight binding at the interface. The present invention also relates to a surface-modified composite and a method for preparing the same. The composite of the present invention which is hydrophobically modified at the surface can adsorb organic solvents such as toluene, dichlorobenzene, petroleum ether and the like, and greases such as gasoline, lubricating oil, motor oil, crude oil and the like, with a weight adsorption ratio of >10.




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Rare earth-containing attrition resistant vanadium trap for catalytic cracking catalyst

The present invention provides a metal passivator/trap comprising a rare earth oxide dispersed on a matrix containing a calcined hydrous kaolin.




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Catalyst compositions for conversion of vegetable oils to hydrocarbon products in the diesel boiling range and process of preparation thereof

The present invention relates to a catalyst composition for conversion of vegetable oils to hydrocarbon products in the diesel boiling range, comprising a porous support; Group III A or VA element in the range of 1-10 wt %; Group VI B elements in the range of 1 to 20 wt %; Group VIII B elements in range of 0.01 to 10 wt %. The present invention further provides the process for preparing the catalyst composition for conversion of vegetable oils to hydrocarbon products in the diesel boiling range. The present invention also provides the process for conversion of vegetable oils to hydrocarbon products in the diesel boiling range using the catalyst composition or discarded refinery spent hydro-treating catalyst.




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Accelerator solution and process for curing curable resins

Solution suitable for accelerating the cure of a curable resin using a peroxide, said accelerator solution comprising (i) at least one organic solvent, (ii) a manganese salt, a copper salt, or a combination thereof, and (iii) an iron complex of a tetradentate, pentadentate or hexadentate nitrogen donor ligand.




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Catalysts for producing hydrogen and synthesis gas

A catalyst which comprises nickel and/or cobalt supported on a support that includes a mixed oxide containing metals, such as aluminum, zirconium, lanthanum, magnesium, cerium, calcium, and yttrium. Such catalysts are useful for converting carbon dioxide to carbon monoxide, and for converting methane to hydrogen.




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Catalysts for making ethanol from acetic acid

Catalysts and processes for forming catalysts for use in hydrogenating acetic acid to form ethanol. In one embodiment, the catalyst comprises a first metal, a silicaceous support, and at least one metasilicate support modifier. Preferably, the first metal is selected from the group consisting of copper, iron, cobalt, nickel, ruthenium, rhodium, palladium, osmium, iridium, platinum, titanium, zinc, chromium, rhenium, molybdenum, and tungsten. In addition the catalyst may comprise a second metal preferably selected from the group consisting of copper, molybdenum, tin, chromium, iron, cobalt, vanadium, tungsten, palladium, platinum, lanthanum, cerium, manganese, ruthenium, rhenium, gold, and nickel.




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Hydroprocessing catalysts and methods for making thereof

A method for preparing an improved slurry catalyst for the upgrade of heavy oil feedstock is provided. In one embodiment, the process comprises: sulfiding at least a metal precursor solution with at least a sulfiding agent forming a sulfided Group VIB catalyst precursor, the metal precursor solution having a pH of at least 4 and a concentration of less than 10 wt. % of Primary metal in solution; and mixing the catalyst precursor with a hydrocarbon diluent to form the slurry catalyst composition. The slurry catalyst prepared therefrom has a BET total surface area of at least 100 m2/g, a total pore volume of at least 0.5 cc/g and a polymodal pore distribution with at least 80% of pore sizes in the range of 5 to 2,000 Angstroms in diameter.




for

Hydroprocessing catalysts and methods for making thereof

A process for making an improved slurry catalyst for the upgrade of heavy oil feedstock is provided. In the process, a metal precursor solution comprising at least a water-soluble molybdenum compound and a water-soluble metal zinc compound is mixed under high shear mixing conditions to generate an emulsion. The emulsion is subsequently sulfided with a sulfiding agent ex-situ, or in-situ in a heavy oil feedstock to form the slurry catalyst. The in-situ sulfidation in heavy oil is under sufficient condition for the heavy oil feedstock to generate the sulfiding source needed for the sulfidation.




for

Process for producing composite oxide catalyst

A process for producing a composite oxide catalyst which includes a step of preparing an aqueous slurry containing at least iron and antimony and composed of a liquid phase and a solid phase, a step of drying the aqueous slurry to obtain a dried material, and a step of calcining the obtained dried material, wherein of the precipitated particles having a particle size of not less than 1 μm but less than 150 μm contained within the aqueous slurry, the proportion of precipitated particles having a particle size of not less than 1 μm but less than 10 μm is within a range from 40 to 90% by volume, and the proportion of precipitated particles having a particle size of not less than 10 μm but less than 150 μm is within a range from 10 to 60% by volume.




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Process for producing Sn-comprising catalysts

The present invention relates to a process for producing a supported tin-comprising catalyst, wherein a solution (S) comprising tin nitrate and at least one complexing agent is applied to the support, where the solution (S) does not comprise any solid or has a solids content of not more than 0.5% by weight based on the total amount of dissolved components.




for

Catalysts for petrochemical catalysis

Metal oxide catalysts comprising various dopants are provided. The catalysts are useful as heterogenous catalysts in a variety of catalytic reactions, for example, the oxidative coupling of methane to C2 hydrocarbons such as ethane and ethylene. Related methods for use and manufacture of the same are also disclosed.




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Method for producing catalyst reforming tar-containing gas, method for reforming tar and method for regenerating catalyst for reforming tar-containing gas

The present invention provides a method for producing a highly active catalyst for reforming tar-containing gas used to treat crude gas for chemical energy conversion consisting of converting to a fuel composition consisting mainly of methane, hydrogen and the like, by utilizing sensible heat possessed by crude gas generated during thermal decomposition of carbonaceous raw materials, and using the high chemical reaction activity of high-temperature tar contained in and incidental to the crude gas to convert the tar to light hydrocarbons in the presence of a catalyst; a tar reforming method; and, a method for regenerating a catalyst for reforming tar-containing gas.




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Cyclodextrin-based polymers for therapeutics delivery

The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.




for

Cyclodextrin-based polymers for therapeutics delivery

The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.




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Paper coating or binding formulations and methods of making and using same

A paper coating or binding formulation comprises an aqueous polymer dispersion comprising a copolymer obtained by polymerization of an unsaturated monomer and a carbohydrate derived compound and a tetrasulfonate-based fluorescent whitening agent. The carbohydrate derived compound can be selected from the group consisting of dextrins, maltodextrins, and mixtures thereof. Methods of preparing a paper coating or binding formulation and improving the whitening properties of paper are also provided. Furthermore, paper including a copolymer obtained by polymerization of an unsaturated monomer and a carbohydrate derived compound and a tetrasulfonate-based fluorescent whitening agent is also disclosed.




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Photosensitizer based on polymer derivatives-photosensitizer conjugates for photodynamic therapy

Disclosed is a novel photosensitizer based on polymer derivatives-photosensitizer conjugates for photodynamic therapy capable of being selectively accumulated in cancerous tissues and producing singlet oxygen or free radical by laser irradiation. The polymer derivatives-photosensitizer conjugates for photodynamic therapy are prepared as nano-sized particles, and have excellent selection and accumulation ratio for cancerous tissues. The photosensitizer conjugates can produce singlet oxygen or free radical by a specific laser wavelength. Owing to the excellent selection and accumulation ratio for cancerous tissues, the conjugates minimizes photo-cytotoxicity of the conventional photosensitizer having a low molecular amount. Accordingly, the conjugates are very useful as a photosensitizes for photodynamic therapy with reduced side effects and excellent therapeutic effectiveness.




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Method for making biodegradable superabsorbent particles

A method for making particles containing carboxyalkyl cellulose, comprising blending a carboxyalkyl cellulose and a starch in water to provide an aqueous gel; treating the aqueous gel with a crosslinking agent to provide a crosslinked gel; drying the crosslinked gel to provide a solid; comminuting the solid to provide a plurality of particles.




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Formaldehyde-free protein-containing binder compositions

One-part binder compositions are described that may include a protein and a crosslinking combination. The crosslinking combination may include at least a first crosslinking compound and a second crosslinking compound. The first and second crosslinking compounds are individually crosslinkable with each other and with the protein. Examples of the protein include soy protein. Fiber products and methods of making the fiber products are also described. The fiber products may include organic fibers, inorganic fibers, or both, in a cured thermoset binder based on solutions of the one-part binder compositions.




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Four branched dendrimer-PEG for conjugation to proteins and peptides

A polymeric dendrimer-like structure with four branches of monomethoxy-polyethylene glycol that can be represented as: The carboxylic group of the previous structure can be functionalized for the production of conjugates of pharmaceutical interest. The binding of this dendrimer-like polyethylene glycol to therapeutic proteins improves their in vitro and in vivo stability.




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Stable reactive thermosetting formulations of reducing sugars and amines

The present invention provides stable aqueous thermosetting binder compositions having a total solids content of 15 wt. % or higher, preferably, 20 wt. % or higher, and having extended shelf life comprising one or more reducing sugar, one or more primary amine compound, and one or more stabilizer acid or salt having a pKa of 8.5 or less. The total amount of stabilizer used may range from 5 to 200 mole %, based on the total moles of primary amine present in the binder. The stabilizer may be an organic stabilizer chosen from a monocarboxylic acid, a dicarboxylic acid, a fatty acid, an acid functional fatty acid ester, an acid functional fatty acid ether, or an inorganic stabilizer chosen from a mineral acid, a mineral acid amine or ammonia salt, and a Lewis acid, and mixtures thereof. The compositions can be used to provide binders for substrate materials including, for example, glass fiber.




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Anti-no-reflow guide wire for vascular interventional procedures

The present invention relates to compositions and methods for improving outcomes in vascular interventional procedures. In particular, the present invention relates to compositions and methods for improving outcomes in vascular interventional procedures using an anti-no-reflow guide wire that attenuates the “no-reflow” phenomenon that is associated with negative outcomes.




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Hydrogel tissue adhesive for medical use

A hydrogel tissue adhesive formed by reacting an aldehyde-functionalized polysaccharide containing pendant aldehyde groups with a water-dispersible, multi-arm amine is described. The hydrogel may be useful as a tissue adhesive or sealant for medical applications that require a more rapid degradation time, such as the prevention of undesired tissue-to tissue adhesions resulting from trauma or surgery.




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Bi-functional co-polymer use for opthalmic and other topical and local applications

The invention contemplates a copolymer which is a graft or block copolymer useful to change wettability and surface characteristics of biological surfaces. Methods for use of these formulations and coatings to change wettability and sterically stabilize, and lubricate biological surfaces in a subject, for example, in the treatment of dry eye syndrome, and to prevent adherence of unwanted proteins, for example in the treatment of contact lens intolerance, are provided.




for

Formaldehyde-free protein-containing binder compositions

A wood-containing composite are described that may include a lignocellulosic material, and a formaldehyde-free binder in contact with at least a portion of the lignocellulose material. The binder is formed from a binder composition that includes a soy flour, a polymer, and a crosslinking agent, at least a portion of each of which are covalently crosslinked to each other in the binder. Also described are methods of making wood-containing composites by providing a pre-mixed, one-part binder composition of at least 60 wt. % soy flour, a polymer, and a crosslinking agent. The binder composition is applied to lignocellulosic material, and the combination may be heated at a temperature of about 100° C. or more to cure the binder composition into a binder. The cured binder has the soy protein, polymer, and crosslinking agent covalently bonded to each other.