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Microfluidic antisolvent crystallization for chiral symmetry breaking

Lab Chip, 2024, 24,5055-5064
DOI: 10.1039/D4LC00658E, Paper
Jiye Jang, Gerard Coquerel, Tae Seok Seo, Woo-Sik Kim, Bum Jun Park
Microfluidic antisolvent crystallization was used to study the effect of solution volume on chiral symmetry breaking (CSB) in NaClO3 crystals. 100% CSB occurs below a critical emulsion volume due to rapid molecule depletion and suppressed nucleation.
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Exploring cancer-associated fibroblast-induced resistance to tyrosine kinase inhibitors in hepatoma cells using a liver-on-a-chip model

Lab Chip, 2024, 24,5043-5054
DOI: 10.1039/D4LC00624K, Paper
Madhu Shree Poddar, Yu-De Chu, Gaurav Pendharkar, Cheng-Hsien Liu, Chau-Ting Yeh
3D liver-on-a-chip reveals AHSG and CLEC3B to mediate cancer-associated fibroblast-induced resistance to TKIs in hepatoma cells.
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Compact lens-free imager using a thin-film transistor for long-term quantitative monitoring of stem cell culture and cardiomyocyte production

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00528G, Paper
Open Access
Taishi Kakizuka, Tohru Natsume, Takeharu Nagai
A novel compact lens-free imager achieved high-throughput long-term monitoring within an incubator, demonstrating the quantification of the confluency of human iPS cells, epithelial-to-mesenchymal transition, and cardiomyocyte beating dynamics.
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Correction: Deciphering hepatoma cell resistance to tyrosine kinase inhibitors: insights from a Liver-on-a-Chip model unveiling tumor endothelial cell mechanisms

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC90093F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Madhu Shree Poddar, Yu-De Chu, Chau-Ting Yeh, Cheng-Hsien Liu
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A gravity-driven tissue chip to study the efficacy and toxicity of cancer therapeutics

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00404C, Paper
Open Access
Pouria Rafsanjani Nejad, Astha Lamichhane, Prasiddha Guragain, Gary Luker, Hossein Tavana
A 96-well plate format, fully-automated multi-organ tissue chip array with gravity-driven flow for cancer research.
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5-axis CNC micro-milling machine for three-dimensional microfluidics

Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D4LC00496E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Mitchell Modarelli, Devin Kot-Thompson, Kazunori Hoshino
The gold standard of microfluidic fabrication techniques, SU-8 patterning, requires photolithography equipment and facilities and is not suitable for 3D microfluidics. A 3D printer is more convenient and may achieve...
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3D-printed microfluidic–microwave device for droplet network formation and characterisation

Lab Chip, 2024, 24,5101-5112
DOI: 10.1039/D4LC00387J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Kai Silver, Jin Li, Adrian Porch, William David Jamieson, Oliver Castell, Pantelitsa Dimitriou, Colin Kallnik, David Barrow
A 3D-printed microwave–microfluidic device using a liquid metal resonator for droplet network formation and characterisation.
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Optical tweezer-assisted cell pairing and fusion for somatic cell nuclear transfer within an open microchannel

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00561A, Paper
Yidi Zhang, Han Zhao, Zhenlin Chen, Zhen Liu, Hanjin Huang, Yun Qu, Yaowei Liu, Mingzhu Sun, Dong Sun, Xin Zhao
We developed a somatic cell nuclear transfer-electrofusion system for pairing and fusing oocytes and somatic cells with a thousand-fold volume difference. The system showed a 90.56% pairing efficiency, potentially boosting batch cloning efficiency.
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Discretised microfluidics for noninvasive health monitoring using sweat sensing

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00763H, Paper
Open Access
Emma J. M. Moonen, Walther Verberne, Eduard Pelssers, Jason Heikenfeld, Jaap M. J. den Toonder
We present the first wearable device with integrated electrowetting, which collects and transports sweat from single glands and measures sweat rate for extremely low sweat rate. This enables non-invasive biomarker monitoring of hospitalized patients.
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Microstring-engineered tension tissues: a novel platform for replicating tissue mechanics and advancing mechanobiology

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00753K, Paper
Zixing Zhou, Tingting Li, Wei Cai, Xiaobin Zhu, Zuoqi Zhang, Guoyou Huang
A simple, cost-effective approach for fabricating soft microstring chips that enables precise engineering of tension tissues (METTs), advancing research in mechanobiology and biomedical applications.
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SERS-based pump-free microfluidic chip sensor for highly sensitive competitive immunoassay of cortisol in human sweat

Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D4LC00858H, Paper
Siyue Xiong, Chushu Zhu, Chengxuan Wang, Peitao Dong, Xuezhong Wu
Cortisol, known as the "stress hormone," is secreted by the adrenal cortex. Measuring cortisol levels in body fluids is essential for evaluating stress levels, adrenal function, hormone imbalances, and psychological...
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Man accused in 25 cases arrested for attempted theft at magistrate’s house in Ernakulam




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Multiple factors remain a hurdle in setting up centralised sewer networks, Kerala govt. informs NGT

Faecal sludge treatment plants proposed in a radius of 15 km on cluster basis in urban and rural local bodies




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Two youngsters from Kochi determined to smash their disabilities on the badminton court

Atul Krishna and Jyothish Kumar defy physical limitations to excel in badminton, inspiring with their determination and talent.




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P.J. Joseph demands govt. intervention in Munambam issue




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HC holds that civil courts have jurisdiction to order execution of decree on Waqf disputes

Petitioners challenge a civil court’s dismissal of a petition filed by them seeking to execute the decree that was passed before the commencement of the Waqf Act. HC asks munsiff court to proceed with the execution petition and pass an order in three months




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Kerala HC adjourns hearing on plea against land acquisition for Wayanad township




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Union Minister Suresh Gopi inaugurates ‘Confluence-24’ in Kochi




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Laugh in life: Kochi-based comedians Abhishek and Akshay on their latest show, their inspirations and more

The duo has been performing stand-up comedy for around three years now.




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Softball teams raise the roof as they whip up excitement at Parade Ground




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Hurdles abound for SilverLine as Railways seek revised DPR for project




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Boxing competition disrupted by man claiming to be YouTuber in Kerala




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Drones to emerge as game changer in fisheries sector, says Union Minister

George Kurian says Centre will develop 100 climate-resilient coastal villages to protect fishers’ livelihood




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Thrissur and Kochi take early lead as curtain goes up on CBSE State Kalotsav




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Coastal States must register all fishing vessels, says Union Minister George Kurian

George Kurian emphasises the need for a framed regulation and policy to improve the livelihood of the fishing community and increase the number of vessels to optimally exploit the country’s marine fisheries resources




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Man accused of raping a tribal Odisha woman engaged as domestic help surrenders before police

Former managing director surrenders after raping tribal woman, sparking protests; accused hospitalised; case under investigation




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State affected due to lack of support from Centre during disasters: Kerala CM

Union government’s attitude reflects a desire for Kerala to suffer, says Pinarayi Vijayan




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Seaplanes have potential to woo high-budget tourists to Kerala: Biju Prabhakar

Aviation Secretary says these amphibious aircraft can link tourism locales in the State. A seaplane will operate a trial service from Kochi International Marina to the Mattupetty dam in Munnar on Monday




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Centre, State must intervene in Munambam Waqf property issue, says Thattil




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Union Minister inaugurates Milma’s fully solar-powered dairy

Milma Federation Chairman K.S. Mani handed over the keys of the Central Quality Control Lab to National Dairy Development Board Chairman Meenesh Shah.




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1,000 consumer clubs to be formed on campuses, says Kerala Minister




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Decision on extending Warehousing Corporation MD’s tenure soon, govt. tells HC




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Kerala School Sports & Games: Dispute over best school winners takes sheen off State school meet

Students and teachers from two schools stage a protest over the result in the best school (athletics) category leading to police intervention during the valedictory function of Kerala School Sports & Games.




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No separate categories of schools in adjudging winners, clarifies Minister




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Grizzly should repeat in the Chief Minister’s Trophy




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Geographique and Regina Memorabilis show out




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Vyasa, Lockheed, Ravishing Form, Nyx and Eastern Gold please




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Chief Minister’s Trophy declared null and void due to false start




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King’s Battalion, Still I Rise, Charukala and Admiral Shaw please




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Isnt She Beautiful for the Mysore Dasara Sprint Championship




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Tom Cruiser wins Mysore Dasara Sprint Championship-2024




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Pissarro for the Suresh Mahindra Trophy




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Santissimo is in great heart




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Redefined upstages Santissimo to claim the HPSL Pune Derby




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Seeking The Stars, Pink Jasmine, Still I Rise and Multiflora catch the eye




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It’s Ravishing Form vs. Segera in the feature event




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Madison, Trigger and Little Minister impress




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Field Of Dreams and Irish Gold excel




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Dyf, Geographique and Regina Memorabilis show out




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Thalassa and Misty catch the eye