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Daily blue-light exposure shortens lifespan and causes brain neurodegeneration in <i>Drosophila</i>




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Phase I trial of maintenance selinexor after allogeneic hematopoietic stem cell transplantation for patients with acute myeloid leukemia and myelodysplastic syndrome




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Donor-derived DNA variability in fingernails of acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation detected by direct PCR




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Safety and efficacy of chimeric antigen receptor T-cell therapy in relapsed/refractory multiple myeloma with renal impairment




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Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE)

Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE.




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Tumor-selective delivery of antisense oligomers (antimiRs) against oncogenic microRNAs

miRNA-targeted antimiRs conjugated to a peptide with a low pH–induced transmembrane structure (pHLIP) could help treat solid tumors.




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RNAi against therapeutic targets with short interfering ribonucleic neutrals (siRNNs)

siRNNs could enable RNAi knockdown of therapeutic targets in a broader range of cells and tissue types than siRNA.




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Tripartite motif containing 37 (TRIM37)

In vitro and mouse studies suggest inhibiting TRIM37 could help treat breast cancer.




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Neutralizing the negatives of RNAi

The siRNN technology that Solstice licensed from UCSD could take RNAi-based therapies to tissues outside the liver and expand their use to a host of new diseases.




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In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states




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Strain creates a trion factory




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Cardamonin protects against lipopolysaccharide-induced myocardial contractile dysfunction in mice through Nrf2-regulated mechanism




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Ex vivo pulsed dendritic cell vaccination against cancer




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Δ<sup>9</sup>-Tetrahydrocannabinol (THC) impairs visual working memory performance: a randomized crossover trial




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Obesity and impaired metabolic health in patients with COVID-19




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Sweet signals — gut–brain circuit for sugar identified




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Wheelchair propulsion fatigue thresholds in electromyographic and ventilatory testing




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Age influences structural brain restoration during weight gain therapy in anorexia nervosa




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Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis




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Predicting brain-disorder risk genes




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Paired TCR discovery in high throughput




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A comparative atlas of the brain




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History Against Sectarianism, The Telegraph

In December 1947, the annual Indian History Congress was held in Bombay. The President-elect that year was Professor Mohammad Habib of the Aligarh Muslim University, a historian of early medieval India, known especially for his studies of the Delhi Sultanate. From the late 1930s, many students and faculty at AMU had been active supporters of [...]




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From Indo-Pak to Chindia and Back Again to Indo-Pak, Hindustan Times

On 26th January 2006, the New York Times ran a story headlined ‘India Everywhere in the Alps’. The story began: ‘Delhi swept into Davos on Wednesday, with an extravagant public relations campaign by India intended to promote the country as the world's next economic superstar, and as a democratic alternative to China for the affections [...]




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Evaluation of an AI system for the detection of diabetic retinopathy from images captured with a handheld portable fundus camera: the MAILOR AI study




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AI papers in ophthalmology made simple




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Protect against market exclusivity in the fight against COVID-19




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Defense Playbook for Campaigns

The 2018 National Defense Strategy (NDS) is predicated on a single organizing principle: America’s military pre-eminence is rapidly eroding. This is not a new concept. For years, experts have warned that the economic and technological advancements of U.S. adversaries, coupled with the 2008 financial crisis and America’s focus on peripheral conflicts, have caused a decline in America’s military dominance. 

In this context, the advances of near-peer competitors such as China and Russia have created plausible “theories of victory” in potential conflicts across Eastern Europe and East Asia. Competitors’ unaddressed improvements in strategic innovation, economic investment, and dual-use technology increases the risk of conflict and strains the U.S. alliance system. It is urgent that the United States reestablish and maintain credible deterrents against these near-peer competitors. After decades of focusing on post-Cold War ‘shaping’ operations, the American military needs to reinvigorate for full spectrum great power competition.

This report is intended as a blueprint on how to begin that process from graduate students at the Belfer Center for Science and International Affairs at Harvard University. Contained inside are 12 memorandums. Each provides a high-level overview and specific recommendations on a key issue of American defense policy. 




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COVID-19's Painful Lesson About Strategy and Power

Joseph Nye writes that while trade wars have set back economic globalization,  the environmental globalization represented by pandemics and climate change is unstoppable. Borders are becoming more porous to everything from drugs to infectious diseases to cyber terrorism, and the United States must use its soft power of attraction to develop networks and institutions that address these new threats.




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Spies Are Fighting a Shadow War Against the Coronavirus

Calder Walton describes four ways how intelligence services are certain to contribute to defeating COVID-19 and why pandemic intelligence will become a central part of future U.S. national security.




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Promoting healthy lifestyle in Chinese college students: evaluation of a social media-based intervention applying the RE-AIM framework




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Comments on “The role of appetite-related hormones, adaptive thermogenesis, perceived hunger and stress in long-term weight-loss maintenance: a mixed-methods study”




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After Social Distancing, a Strange Purgatory Awaits

Life right now feels very odd. And it will feel odd for months—and even years—to come.




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What I Wish I Had Said on CNN About Trump's 'Lysol and Sunshine' Speech

Joel Clement appeared on CNN's Erin Burnett OutFront on April 23, 2020.  In this blog post for the Union of Concerned Scientists, he elaborates on what he wishes he had said during that interview.




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An Abysmal Failure of Leadership

During times of crisis, the most effective leaders are those who can build solidarity by educating the public about its own interests. Sadly, in the case of COVID-19, the leaders of the world's two largest economies have gone in the opposite direction, all but ensuring that the crisis will deepen.




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After Social Distancing, a Strange Purgatory Awaits

Life right now feels very odd. And it will feel odd for months—and even years—to come.




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What I Wish I Had Said on CNN About Trump's 'Lysol and Sunshine' Speech

Joel Clement appeared on CNN's Erin Burnett OutFront on April 23, 2020.  In this blog post for the Union of Concerned Scientists, he elaborates on what he wishes he had said during that interview.




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An Abysmal Failure of Leadership

During times of crisis, the most effective leaders are those who can build solidarity by educating the public about its own interests. Sadly, in the case of COVID-19, the leaders of the world's two largest economies have gone in the opposite direction, all but ensuring that the crisis will deepen.




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Genome-wide selection and genetic improvement during modern maize breeding




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Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease




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ZBP1 (DAI/DLM-1) promotes osteogenic differentiation while inhibiting adipogenic differentiation in mesenchymal stem cells through a positive feedback loop of Wnt/β-catenin signaling




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The COVID-19 Distance Learning: Insight from Ukrainian students

Nenko, Yuliia and Кybalna, Nelia and Snisarenko, Yana The COVID-19 Distance Learning: Insight from Ukrainian students. Revista Brasileira de Educação do Campo, 2020, vol. 5, pp. 1-19. [Journal article (Paginated)]




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Comunicación y crisis del coronavirus en España. Primeras lecciones // Communication and coronavirus crisis in Spain. First lessons

Costa-Sánchez, Carmen and López-García, Xosé Comunicación y crisis del coronavirus en España. Primeras lecciones // Communication and coronavirus crisis in Spain. First lessons. El profesional de la información, 2020, vol. 29, n. 3. [Journal article (Unpaginated)]




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Living with Uncertainty: Modeling China's Nuclear Survivability

A simplified nuclear exchange model demonstrates that China’s ability to launch a successful nuclear retaliatory strike in response to an adversary’s nuclear first strike has been and remains far from assured. This study suggests that China’s criterion for effective nuclear deterrence is very low.




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Spying: Hiding in Plain Sight

Spycraft has always excited people, with stories of daring agents using high-tech wizardry to bust terrorists in the act. But the reality is much less glamorous—and much more dangerous. As spying entered the 1960s, technology started to play a serious role in getting intel. 




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Washington Should Take Action on AI or Stay Out of the Way

Federal and local regulations are part of the solution to tough issues related to Artificial Intelligence, writes K. Gretchen Greene, but no regulatory approach on its own can fully answer these questions today. "Finding answers will require significant investments in research and development, collaboration, negotiation, and experimentation, deep and careful thought across many fields and leadership at all levels, across and between governments. The U.S. federal government is well positioned to lead, but if it won't, it should at least stay out of the way."




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COVID-19's Painful Lesson About Strategy and Power

Joseph Nye writes that while trade wars have set back economic globalization,  the environmental globalization represented by pandemics and climate change is unstoppable. Borders are becoming more porous to everything from drugs to infectious diseases to cyber terrorism, and the United States must use its soft power of attraction to develop networks and institutions that address these new threats.




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China and America Are Failing the Pandemic Test

All national leaders must put their countr's interests first, but the important question is how broadly or narrowly they define those interests. Both China and the US are responding to COVID-19 with an inclination toward short-term, zero-sum approaches, and too little attention to international institutions and cooperation.




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New Committee to Advise Bacow on Sustainability Goals

Harvard University has created a Presidential Committee on Sustainability (PCS) to advise President Larry Bacow and the University's leadership on sustainability vision, goals, strategy, and partnerships. The Harvard Gazette spoke with committee chairs Rebecca Henderson, the John and Natty McArthur University Professor; John Holdren, the Teresa and John Heinz Professor of Environmental Policy at Harvard Kennedy School; and Katie Lapp, executive vice president, about why it is so important to act now; the role of the PCS in developing collaborative and innovative projects; and how the campus community can get involved.




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What I Wish I Had Said on CNN About Trump's 'Lysol and Sunshine' Speech

Joel Clement appeared on CNN's Erin Burnett OutFront on April 23, 2020.  In this blog post for the Union of Concerned Scientists, he elaborates on what he wishes he had said during that interview.