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Real-time monitoring of a 3D blood–brain barrier model maturation and integrity with a sensorized microfluidic device

Lab Chip, 2024, 24,5085-5100
DOI: 10.1039/D4LC00633J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Maria Cristina Ceccarelli, Marie Celine Lefevre, Attilio Marino, Francesca Pignatelli, Katarzyna Krukiewicz, Matteo Battaglini, Gianni Ciofani
A new in vitro sensorized model of the blood–brain barrier has been developed and characterized.
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Acoustic enrichment of sperm for in vitro fertilization

Lab Chip, 2024, 24,5113-5123
DOI: 10.1039/D4LC00604F, Paper
Open Access
Chunqiu Zhang, Ning Rong, Ziyi Lin, Peng-Qi Li, Jingyao Shi, Wei Zhou, Lili Niu, Fei Li, Rongxin Tang, Lei Li, Long Meng
This study introduces an acoustofluidic device that leverages acoustic streaming to efficiently accumulate sperm. Importantly, ultrasound significantly improves sperm motility, increases fertilization rates and accelerates multicellular development.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Optical tweezer-assisted cell pairing and fusion for somatic cell nuclear transfer within an open microchannel

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00561A, Paper
Yidi Zhang, Han Zhao, Zhenlin Chen, Zhen Liu, Hanjin Huang, Yun Qu, Yaowei Liu, Mingzhu Sun, Dong Sun, Xin Zhao
We developed a somatic cell nuclear transfer-electrofusion system for pairing and fusing oocytes and somatic cells with a thousand-fold volume difference. The system showed a 90.56% pairing efficiency, potentially boosting batch cloning efficiency.
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Dual-drive acoustic micromixer for rapid nucleation and ultrafast growth of perovskite nanoparticles

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00721B, Paper
Zhifang Liu, Yuwen Lu, Wei Tan, Guorui Zhu
An acoustic micromixer driven by bubbles and sharp edges, controlling the nucleation and growth of perovskite nanoparticles.
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Discretised microfluidics for noninvasive health monitoring using sweat sensing

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00763H, Paper
Open Access
Emma J. M. Moonen, Walther Verberne, Eduard Pelssers, Jason Heikenfeld, Jaap M. J. den Toonder
We present the first wearable device with integrated electrowetting, which collects and transports sweat from single glands and measures sweat rate for extremely low sweat rate. This enables non-invasive biomarker monitoring of hospitalized patients.
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An imaging scheme to study the flow dynamics of co-flow regimes in microfluidics: implications for nanoprecipitation

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00652F, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Wali Inam, Anton Vladyka, Joanna W. Pylvänäinen, Junel Solis, Dado Tokic, Pasi Kankaanpää, Hongbo Zhang
Herein, by presenting a novel imaging-based scheme for analyzing fluid interactions in co-flow regimes, we identify oscillatory and chaotic flow behaviors to optimize nanoprecipitation through controlled fluid manipulation.
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SERS-based pump-free microfluidic chip sensor for highly sensitive competitive immunoassay of cortisol in human sweat

Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D4LC00858H, Paper
Siyue Xiong, Chushu Zhu, Chengxuan Wang, Peitao Dong, Xuezhong Wu
Cortisol, known as the "stress hormone," is secreted by the adrenal cortex. Measuring cortisol levels in body fluids is essential for evaluating stress levels, adrenal function, hormone imbalances, and psychological...
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Man armed with machete creates tension in Aluva




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Kerala State school sports meet off to a vibrant start with grand inaugural ceremony

The inaugural ceremony featured a march past with student athletes from 14 districts and the United Arab Emirates (UAE) parading from Durbar Hall Ground to the college ground




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KITE gives technological edge to coverage of State school sports meet




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Two youngsters from Kochi determined to smash their disabilities on the badminton court

Atul Krishna and Jyothish Kumar defy physical limitations to excel in badminton, inspiring with their determination and talent.




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Malankara Metropolitan Joseph Gregorios to lead Jacobite Syrian Church temporarily




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Demand for wayside amenities along NHs, Centre’s policy may be of help

PWD pursuing the matter with NHAI, since such amenities will help drivers and others to take a break. ‘Humsafar policy’ of the Centre, launched a month ago, aims to accelerate development of wayside amenities beside highways, if need be with private participation




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Drenched in sweat, student volunteers have a bittersweet experience at sports meet in Kochi




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Kerala HC adjourns hearing on plea against land acquisition for Wayanad township




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Thammanam-Pullepady Road development: joint site inspection planned

Landowners along the stretch seek adequate compensation for small tracts of additional land that will be acquired in keeping with the revised alignment




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Civic authorities racing against time to save Central funds for Edakochi STP

The deadline for the ₹18.6-crore project is December 31, and failure to complete it in time will lead to the Corporation losing the Central share of ₹7.75 crore




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Allow only dolly workers with police verification certificate to carry pilgrims to Sabarimala: Kerala HC




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Hema Committee report: Preliminary inquiry in cases to be completed by December-end, Kerala govt tells HC

Submission made in a progress report filed by Kerala govt in response to public interest litigation in High Court filed in connection with Hema Committee report




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Kerala State Sports & Games 2024: curiosity pulls in more people to baseball games

Though not a very popular game like cricket, more youngsters are getting drawn into the sport, says a baseball coach




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A man’s love affair with a sport that gave him a life




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Softball teams raise the roof as they whip up excitement at Parade Ground




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Syro-Malabar Church affirms solidarity with Munambam protesters

State government must urgently intervene in the issue, since hundreds of families are facing threat of displacement from the land they had purchased and had been staying in for decades, says Church spokesperson




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Boxing competition disrupted by man claiming to be YouTuber in Kerala




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Kerala man arrested with nitrazepam tablets




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Contempt case hearing against Kerala govt. adjourned in directive to take over Jacobite churches




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About 10 lakh tonnes of legacy waste awaiting scientific remediation




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Kerala, Tamil Nadu united to ensure that India belongs to everyone, says Kanimozhi

DMK MP Kanimozhi was addressing an event held at the Ernakulam Town Hall to felicitate Sr. Vinitha, director of St. Teresa’s College, for her contributions to higher education, social welfare, and culture.




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Perumbavoor Urban Cooperative Society to witness novel election as aggrieved investors set to field panel to seize control

Election for 11-member board set for November 24 after cooperative faces financial crisis due to alleged fraud in loan valuations and sanctions




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Delay in completing work on ferry jetties hits commuters in West Kochi

Irrigation department is reportedly being blamed for the delay in completing dredging at Mattancherry Jetty; delay in renovating the Customs Jetty is causing safety issues, CSML asks contractor to expedite work




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HC asks Wayanad DLSA to formulate action plan to prevent child marriages among tribal communities




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HC tells authorities to prevent anti-social activities by other methods before resorting to KAAPA




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Action initiated against units lacking sewage treatment facilities, Environment dept. tells NGT




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Detailed probe launched into fire at commercial unit near Aluva




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IBM’s new GenAI Innovation Centre to open doors to all looking to experiment with its AI platform




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Hyper colour-sensitivity

Indians in general and North Indians in particular are hypersensitive to skin colour. Fairer the skin, the higher the presumed social status and societal acceptance. Even the caste system was originally based on skin colour (varna in Sanskrit).



  • R K Nair

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Hits below the belt

"John le Carré's conduct in your pages is like ... that of a man who, having relieved himself in his own hat, makes haste to clamp the brimming chapeau on his head."



  • R K Nair

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Cashing in on calamity

Fleecing the pilgrims is big business in this country.



  • R K Nair

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Political soap opera



  • R K Nair

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Primitive blame game

The latest controversy gives rise to a nagging suspicion: Were the utterances of the Kerala Chief Minister and his Cabinet colleague aimed at deflecting attention from the raging solar scam?



  • R K Nair

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'Spirit'ual Kerala



  • R K Nair

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The politics of child marriage

India's stand at the UN Human Rights Council was viewed with apprehension by the intelligentsia in Kerala. Many see it as yet another example of appeasement politics.



  • R K Nair

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Mescalito impresses




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African Gold, Czar, Double Scotch, My Solitaire, Jersey King and Magnetic shine




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Mojito and Waikiki impress




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It’s My Time and Dyf show out




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Mojito, Rasputin and Booster Shot catch the eye




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It’s Ravishing Form vs. Segera in the feature event




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Madison, Trigger and Little Minister impress




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Trevalius, Inspire, Finley, Mescalito and Vivaldo shine