nc

Efficacy of Melatonin in Children With Postconcussive Symptoms: A Randomized Clinical Trial

BACKGROUND:

Approximately 25% of children with concussion have persistent postconcussive symptoms (PPCS) with resultant significant impacts on quality of life. Melatonin has significant neuroprotective properties, and promising preclinical data suggest its potential to improve outcomes after traumatic brain injury. We hypothesized that treatment with melatonin would result in a greater decrease in PPCS symptoms when compared with a placebo.

METHODS:

We conducted a randomized, double-blind trial of 3 or 10 mg of melatonin compared with a placebo (NCT01874847). We included youth (ages 8–18 years) with PPCS at 4 to 6 weeks after mild traumatic brain injury. Those with significant medical or psychiatric histories or a previous concussion within the last 3 months were excluded. The primary outcome was change in the total youth self-reported Post-Concussion Symptom Inventory score measured after 28 days of treatment. Secondary outcomes included change in health-related quality of life, cognition, and sleep.

RESULTS:

Ninety-nine children (mean age: 13.8 years; SD = 2.6 years; 58% girls) were randomly assigned. Symptoms improved over time with a median Post-Concussion Symptom Inventory change score of –21 (95% confidence interval [CI]: –16 to –27). There was no significant effect of melatonin when compared with a placebo in the intention-to-treat analysis (3 mg melatonin, –2 [95% CI: –13 to 6]; 10 mg melatonin, 4 [95% CI: –7 to 14]). No significant group differences in secondary outcomes were observed. Side effects were mild and similar to the placebo.

CONCLUSIONS:

Children with PPCS had significant impairment in their quality of life. Seventy-eight percent demonstrated significant recovery between 1 and 3 months postinjury. This clinical trial does not support the use of melatonin for the treatment of pediatric PPCS.




nc

Transgender Youth Experiences and Perspectives Related to HIV Preventive Services

BACKGROUND:

In the United States, transgender youth are at especially high risk for HIV infection. Literature regarding HIV prevention strategies for this vulnerable, often-hidden population is scant. Before effective, population-based HIV prevention strategies may be adequately developed, it is necessary to first enhance the contextual understanding of transgender youth HIV risk and experiences with HIV preventive services.

METHODS:

Two 3-day, online, asynchronous focus groups were conducted with transgender youth from across the United States to better understand participant HIV risk and experiences with HIV preventive services. Participants were recruited by using online advertisements posted via youth organizations. Qualitative data were analyzed by using content analysis.

RESULTS:

A total of 30 transgender youth participated. The average age was 18.6 years, and youth reported a wide range of gender identities (eg, 27% were transgender male, 17% were transgender female, and 27% used ≥1 term) and sexual orientations. Four themes emerged: (1) barriers to self-efficacy in sexual decision-making; (2) safety concerns, fear, and other challenges in forming romantic and/or sexual relationships; (3) need for support and education; and (4) desire for affirmative and culturally competent experiences and interactions (eg, home, school, and health care).

CONCLUSIONS:

Youth discussed experiences and perspectives related to their gender identities, sexual health education, and HIV preventive services. Findings should inform intervention development to improve support and/or services, including the following: (1) increasing provider knowledge and skills to provide gender-affirming care, (2) addressing barriers to services (eg, accessibility and affordability as well as stigma and discrimination), and (3) expanding sexual health education to be inclusive of all gender identities, sexual orientations, and definitions of sex and sexual activity.




nc

Valencia v Atalanta facts

Valencia will need to must a remarkable home recovery to turn round their tie against Atalanta after a 4-1 first-leg defeat.




nc

Manchester City v Real Madrid facts

A first-leg comeback has put Manchester City in the driving seat as Real Madrid travel to north-west England facing a 2-1 deficit.




nc

Could Artificial Intelligence Automate Student Note-Taking?

An AI-powered digital assistant to take notes for you? It’s already happening in the workplace, but classroom note taking could prove harder to automate.




nc

Hintzes commit $100,000 for emergency aid to students

Two of Penn State’s most generous supporters and prominent alumni leaders have made a new commitment to support students impacted by the COVID-19 crisis. Helen S. Hintz, 1960, and Edward “Ed” R. Hintz, 1959, have directed $100,000 to the Student Care and Advocacy Emergency Fund.




nc

Penn State cancer research center joins pandemic fight

The Penn State Center for Structural Oncology is shifting some of its focus from fighting cancer to fighting COVID-19, with three projects.




nc

Lehigh Valley LaunchBox grant recipients help COVID-19 relief efforts

Using their unique skills and experiences, three LaunchBox grant recipients are providing a variety of COVID-19 relief efforts.




nc

Penn State Lehigh Valley announces 2020 student life and athletics award winners

Students celebrated for athletic and student life achievements during the Finally Finished Fest




nc

E-cigarette Product Characteristics and Subsequent Frequency of Cigarette Smoking

Jessica L. Barrington-Trimis
May 1, 2020; 145:e20191652-e20191652
ARTICLES




nc

Antibiotic Use and Outcomes in Children in the Emergency Department With Suspected Pneumonia

Matthew J. Lipshaw
Apr 1, 2020; 145:e20193138-e20193138
ARTICLES




nc

Benign Neonatal Shudders, Shivers, Jitteriness, or Tremors: Early Signs of Vitamin D Deficiency

Millicent Collins
Aug 1, 2017; 140:e20160719-e20160719
CASE REPORTS




nc

Spain win #WU17EURO: at a glance

Spain ended Germany's two-year reign as champions to claim their fourth title.




nc

Germany win #WU17EURO: at a glance

Germany pipped the Netherlands on penalties to make it seven titles in the 12 #WU17EURO seasons.




nc

Fin24.com | Don't get a nasty surprise! How to understand insurance jargon

Are you sure you know what the "insurance speak" in your policy means?




nc

Fin24.com | Organisation with an interest in financial literacy, invited to take part in Money Smart Week

Money Smart Week SA, a financial literacy campaign aimed at motivating and empowering South Africans to become more educated about their finances, is taking place from March 23 to 28, 2020.




nc

Fin24.com | Here's what SA financial experts would do with R10 000 in 2020

Fin24 asked financial experts how they would grow R10 000 in the new year. Here's what they said.




nc

Fin24.com | Experts say the Section 12J incentive is misunderstood - we asked them to explain

Many investors do not fully understand the tax incentive and structure of a Section 12J venture capital investment, according to a managing director involved in this sector.




nc

Fin24.com | Free online financial literacy short course

Metropolitan is sponsoring a financial literacy short course hosted on FunDza, an online literacy portal dedicated to helping South Africans better their skills.




nc

How Gun Violence Is Changing Friday Night Football

As shootings break out at high school athletic events, districts must grapple with major questions about their role in keeping venues safe.




nc

Groups seek injunction to stop Idaho transgender sports ban




nc

North Dakota spring high school sports, activities cancelled




nc

Digital Fluency Project goes remote at Penn State Greater Allegheny

A signature program at Penn State Greater Allegheny, implemented to give students, faculty and staff the digital skills to communicate, solve problems and create new knowledge, is front and center in the University’s remote learning period.




nc

Slade recognized with Jackson Lethbridge Tolerance Award

Ebonie Slade, a senior majoring in biobehavioral health at Penn State Greater Allegheny, is the recipient of the 2020 Jackson Lethbridge Tolerance Award.




nc

2020 Penn State student award recipients announced

Each year, Penn State honors several students for the highest levels of academic excellence, outstanding leadership and meritorious service. The 2020 student award recipients exemplify best practices and achievements among Penn State students, reflecting the University's mission of teaching, research and service.




nc

Student Engagement Network announces newest members of Faculty Academy

The Student Engagement Network's Faculty Academy funds projects developed by Penn State faculty that result in transformative experiences that complement student engagement.




nc

France, Poland, Romania, Serbia come through play-offs

France beat Croatia to earn a final tournament debut, as they joined Serbia, Romania and Poland in qualifying for UEFA Futsal EURO 2018 via the play-offs.




nc

Portugal win Futsal EURO, Ricardinho top scorer: at a glance

Portugal are UEFA Futsal EURO winners for the first time while Ricardinho dominated the individual honours in a record-breaking personal tournament: the full story.




nc

Penn State Hazleton fall 2019 dean's list announced

More than 200 students from Penn State Hazleton were recently named to the dean’s list for the fall 2019 semester.




nc

Legal clinic at Happy Valley LaunchBox expands scope in response to pandemic

Effective immediately and for the foreseeable future, the Entrepreneurship and Assistance Clinic is expanding its scope and service offerings to small Pennsylvania businesses, in response to the COVID-19 pandemic.




nc

Fish, wine, and social media: Hazleton virtual research fair winners announced

Wine, fish, and excessive use of social media were a few of the topics that earned students top honors in Penn State Hazleton's first-ever virtual Undergraduate Research Fair.




nc

Students on School Boards: Balancing Representation and Fairness

Having student board members with voting clout on school boards poses a number of logistical challenges, readers say in response to a recent Education Week feature.




nc

Video-Based Teacher Collaboration Helps Teachers Find the 'Story of Science'

After a successful pilot, a professional development program is looking to expand its lesson-study approach to rural teachers.




nc

Nontraditional Pets Policy--Reaffirmed With Reference & Data Updates




nc

Polio Policy: Reaffirmed With Reference and Data Updates




nc

Deals: Acer Computers, Blink XT2, 65-Inch Vizio P-Series Quantum X

Amazon is offering up to 30 percent off Acer laptops, desktops, and monitors. Plus, you can save $930 on the 65-inch Vizio P-Series Quantum X 4K TV.




nc

The Best Android Launchers for Home Screen Customization

Don't settle for the default settings on your Android device. With the right launcher, you can customize the screens and layouts of your phone.




nc

Microsoft Enhances OneDrive With a Personal Vault

Alongside a new protected area of storage, OneDrive and Office 365 storage options are changing for the better.




nc

Weekend Deals: Logitech Webcam, 65-Inch Vizio, Dell Inspiron 15 5000

The Logitech C920 1080p webcam is back down to its Prime Day price, the 65-inch Vizio P-Series Quantum 4K TV is on sale for less than $1,000, and you can grab the new Dell Inspiron 15 5000 plus a $100 Visa prepaid card for just $600.




nc

Deals: Amazon Echo Dot, 55-Inch Vizio 4K Smart TV, More

Right now you can grab an Amazon Echo Dot two-speaker bundle for just $50. Plus, the 55-inch Vizio M-Series Quantum 4K Smart TV and Anker charging accessories are on sale.




nc

Western Digital Launches 5 WD Black External Gaming Drives

Capacities range from 2TB right up to 12TB, with the P50 Game Drive boasting a 'first-to-industry' USB 3.2 gen 2x2 connection and 2,000MB/s read speeds.




nc

Deals: Samsung 1TB SSD, 10.2-Inch Apple iPad, 13-Inch MacBook Pro

The 1TB Samsung 860 EVO m.2 SSD is just $119 today, the 10.2-inch iPad is back in stock with a 15 percent discount, and you can save $250 on the 13-inch MacBook Pro.




nc

Snag a 50-Inch Sceptre 4K Ultra HD TV for Just $200

Normally $399.99, the Sceptre U515CV-U is available at Walmart right now for just $199.99. Don't miss this chance to snag it for half off.




nc

Roku Announces 'Roku TV Ready' and 15 Roku TV Brands

Own a Roku TV? Audio equipment can now be certified to be 'Roku TV Ready' meaning setup is simplified and control only requires one remote.




nc

Sony's CES TV Lineup Includes 8K, a Smaller 4K OLED, Audio Tricks

The Z8H 8K LED vibrates the frame of the television to emit audio and give the impression that the sound is coming directly from the screen itself.




nc

Get a 50-Inch Samsung 4K Smart TV for $295

This is a 2018 model, but it's got tons of bells and whistles such as 4K ultra high-definition (2160p) picture, built-in Wi-Fi and smart functionality, and High Dynamic Range support.




nc

Save $800 on a 65-Inch LG 4K OLED TV in Time for Super Bowl Sunday

Don't watch the Super Bowl on your old, grainy TV. Head over to the PCMag Shop to score a big discount on the 65-Inch LG OLED B9 Series 4K smart OLED TV.




nc

Help for Principals Who Want to Support Special Education Teachers and Students

A new guide from the National Center for Learning Disabilities and Understood.org offers advice on how school leaders can best serve students with disabilities and support special education teachers.




nc

Principals Say They Need Help to Support Students With Disabilities

The need for materials, training, guidance from district administrators, and access to staff with expertise in serving students with disabilities is especially acute in schools that serve primarily black and Latino students, a new survey finds.




nc

Education Groups Seek Over $200 Billion in New Coronavirus Emergency Aid

The two national teachers' unions and other prominent groups are seeking $175 billion for state K-12 budgets, $13 billion in dedicated aid for special education, and more to help schools deal with the coronavirus.