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Business with a heart

Dharti Jute Emporium rides on the twin causes of women empowerment and spreading eco-awareness




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Moulded with clay, perfected by art

A group of artisans from West Bengal have been making Ganesh idols for the past 10 months at Indira Park for the SAVE group. Here’s a look at the art of making clay idols




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Woven with care




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Alluring golu dolls beckon visitors

Price ranges from Rs.50 to Rs.16,000; 10% discount up for grabs




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Exhibition of traditional items




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Truck it!

Make your very own special super storage truck to keep your toys, pencils, colours and anything else that might be lying around your room.




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Experimenting with beads

IT professional Anitha Sanju makes customised jewellery under the brand Glitter n’ Hues




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Delhi International Kite Festival 2012

Delhi Tourism hosted the second edition of its International Kite Festival.




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Catch up with the latest trends




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Do it with design

National Institute of Design’s annual Design Summit held in Delhi this week threw up a host of designer products




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Thinking stitches

Designer Isha Kapoor feels good casual wear, specially in cotton, is hard to find




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A new look at the deity

Jayaprakash sculpts the female form with an African inspiration




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Pitching on the Patola

Narshi Bhai’s Patola saris and dupattas are works of fine craftsmanship. They are on display at Basava Ambara.




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Creativity in every fold

Their passion for folding paper to create exciting shapes led to their forming the Origami Society of Madras. T. Subash and V. R. Karthik talk about their unusual hobby




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Visitors throng crafts festival

The 10-day carnival has a wide range of products on display




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Mamallapuram to host Tamil Nadu International Kite Festival for the first time

The maiden edition of Tamil Nadu Kite Festival is set to see custom kites, brought in by professionals from USA, Thailand, Malaysia and India, take flight



  • Life & Style

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Traditional Indian art is witnessing a contemporary makeover. And the art market is loving it

Tribal and traditional artists explore novel ways of storytelling, experimenting with colour, techniques and contemporary themes, to connect with younger, mainstream audiences




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Label Erode’s debut collection blends the GI-tagged jamakkalam with Jimi Hendrix’s music

How a Mumbai-based fashion label is reviving the GI-tagged Bhavani jamakkalam through its debut collection




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Photocatalytic hydrotrichloromethylation of unactivated alkenes with chloroform

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01496K, Research Article
Dawei Gong, Caiyu Gao, Qixuan Li, Yufei Li, Lina Zhao, Degong Kong
Trichloromethyl compounds are essential constituents in synthetic and medicinal chemistry.
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State-of-the-art strategies for Lewis acid-catalyzed strain-release cycloadditions of bicyclo[1.1.0]butanes (BCBs)

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01741B, Review Article
Xiang Liu, Jiawei He, Keyu Lin, Xingyue Wang, Hua Cao
This review primarily focuses on the latest developments in Lewis acid-catalyzed strain-release cycloaddition reactions of BCBs.
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Multi-step chirality transfer and racemization kinetics of pillar [5]arenes by tuning the halogen substituents on the rims

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01799D, Research Article
Lizhi Fang, Xiaowen Guan, Yanling Shen, Dayang Zhou, Long Chen, Xiaochuan Chen, Wanhua Wu, Leyong Wang, Cheng Yang
Halogen-substituted pillar[5]arenes exhibited hindered hydroquinone subunit flipping, enabling enantioseparation.
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Shaping cycles with light: a regiodivergent approach to tetracyclic aza-aromatic compounds

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01606H, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Clara Mañas, Belén Ibarra, Estíbaliz Merino
We present a novel visible light-promoted regiodivergent cyclization, enabling the selective synthesis of distinct azapolyaromatic regioisomers from 2-alkynlazobenzenes.
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Visible-light heterogeneous photocatalysis with an ionic porous organic polymer (IPOP): synthesis of β-keto sulfoxides and benzothiophene diesters by tandem radical addition–oxidation reactions

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01382D, Research Article
Ajay Kumar Sahoo, Parag Tamuly, Jarugu Narasimha Moorthy
An IPOP, constructed constructed from cyanuric chloride and the readily accessible 2,5-di(pyridin-4-yl)thiazolo[5,4-d]thiazole (BpyTzTz), is shown to exhibit excellent visible light absorption and serve as a metal-free heterogeneous photocatalyst.
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Iron-catalyzed thiolation of C(sp3)–H with sulfonyl chlorides via photoinduced ligand-to-metal charge transfer

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01488J, Research Article
Sheng-Ping Liu, Lan Yang, Yan-Hong He, Zhi Guan
A photoinduced FeCl3/HCl synergistic catalytic method enables C(sp3)–S bond formation via reductive cross-coupling of activated/inert C(sp3)–H and aryl/alkyl sulfonyl chlorides through ligand-to-metal charge transfer (LMCT).
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Palladium-catalyzed hydrocarbonylative cross-coupling with two different alkenes

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01312C, Research Article
Yi Chen, Jianing Wu, Yongzheng Ding, Hanmin Huang
Transition metal-catalyzed hydrocarbonylation of alkenes has been widely studied; however, the hydrocarbonylation reaction that took place between two alkenes has been largely unexplored.
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HSAB theory guiding electrophilic substitution reactions of o-carborane

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01546K, Research Article
Yan Wang, Yi-Ge Li, Feijing Chen, Yan-Na Ma, Xuenian Chen
Herein, we systematically compared the reactivity of o-carborane and benzene toward different electrophiles and explained the results with the HSAB principle.
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Mechanistic insight into the dehydrogenation reaction catalyzed by an MLC catalyst with dual ancillary ligand sites

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01767F, Research Article
Gui-Xiang Zhou, Cheng Hou
This study reveals a mechanism in which a ruthenium complex catalyst improves catalytic efficiency and lowers the energy barrier in the dehydrogenation of benzyl alcohol by dynamically switching ligand sites.
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Synthesis of bambusurils with perfluoroalkylthiobenzyl groups as highly potent halide receptors

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01746C, Research Article
Open Access
Matúš Chvojka, Hennie Valkenier, Vladimír Šindelář
Four new fluorinated bambusuril macrocycles were prepared to show exceptional high binding affinity towards halide anions in acetonitrile.
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Stereoselective access to furan-fused [5.5.0] bicyclic heterocycles enabled by gold-catalyzed asymmetric [8 + 4] cycloaddition

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01841A, Research Article
Xunhua Wang, Jianhua Wang, Xiaoxun Li
A gold-catalyzed asymmetric [8 + 4] cycloaddition was developed to afford highly functionalized furan/pyrrole-fused [5.5.0] polycyclic heterocycles with good diastereo- and enantioselectivity.
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Photoinduced cobaloxime catalysis for allylic mono- and diphosphinylation of alkenes with hydrogen evolution

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01638F, Research Article
Aijun Zhang, Miao-Miao Li, Lei Guo, Huaixiang Yang, Jiefei Guo, Da Xu, Wei Ding
A highly efficient allylic radical mono- and diphosphinylation of alkenes with secondary phosphine oxides is developed, via visible-light-induced cobaloxime catalysis.
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The reactivity of alkenyl boron reagents in catalytic reactions: recent advances and perspectives

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01703J, Review Article
Ya-Li Feng, Bo-Wen Zhang, Youzhi Xu, Shengnan Jin, Daniele Mazzarella, Zhong-Yan Cao
Recent advances focusing on novel reactivity of alkenyl boron reagents in polar or radical pathways within catalytic reactions by employing transition metal catalysis, organocatalysis have been summarized and discussed.
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Visible-light excited copper activating unactivated alkyl iodides for radical addition/cyclization to access oxindole derivatives

Org. Chem. Front., 2024, 11,6380-6384
DOI: 10.1039/D4QO01329H, Research Article
Hang Luo, Fangnian Yu, Luqing Lin
The photocopper catalyst facilitates halogen atom transfer to give unactivated alkyl radicals, which is critical for achieving radical cyclization in the absence of an exogenous photocatalyst.
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Transition-metal-catalyzed regiodivergent sulfonylation of aziridrines for the synthesis of β-amino sulfones

Org. Chem. Front., 2024, 11,6340-6346
DOI: 10.1039/D4QO01376J, Research Article
Qinqiong Zeng, Yujia Gong, Xiaochun He, Xuemei Zhang, Zhong Lian
We developed the first transition-metal-catalyzed, regiodivergent sulfonylation of aziridines, enabling the efficient synthesis of diverse β-amino sulfones under mild conditions with broad substrate compatibility and high regioselectivity.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Phosphine-controlled divergent reactions of MBH-carbonates with azaheptafulvenes: access to o-anilinyl diene and benzazepine derivatives

Org. Chem. Front., 2024, 11,6418-6425
DOI: 10.1039/D4QO01298D, Research Article
Wei Hao, Yiwen Zhang, Xiao Han, Zhen Wang, Weijun Yao
A phosphine controlled divergent cascade reaction of MBH-carbonates with azaheptafulvenes was disclosed. PPh3 provided o-aminophenyl diene while PCy3 offered benzazepine derivative through formal [8 + 3] annulation/ring contraction cascade.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A cucurbit[8]uril-mediated host–guest complex for red-light photocatalysis

Org. Chem. Front., 2024, 11,6327-6332
DOI: 10.1039/D4QO01492H, Research Article
Weiquan Xu, Yinghao Du, He Ma, Xingchen Tang, Jiang-Fei Xu, Xi Zhang
Two-step host–guest complexation can occur between an elongated dye and CB[8], leading to the formation of CB[8]@2TPP and 3CB[8]@2TPP sequentially. Of these species, 3CB[8]@2TPP in particular can act as an efficient red-light photocatalyst.
The content of this RSS Feed (c) The Royal Society of Chemistry




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18F-labelling of nitrogen-containing aryl boronates – anti-cancer drug melflufen as a case study

Org. Chem. Front., 2024, 11,6411-6417
DOI: 10.1039/D4QO01594K, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Kevin Bajerke, Fredrik Lehmann, Gunnar Antoni, Kálmán J. Szabó
This study addresses the 18F-labelling of nitrogen-containing arenes via copper-mediated radiofluorination (CMRF). In this case study, derivatives/fragments of the anti-cancer drug melflufen were targeted.
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Theoretical insights into Pd-catalyzed dual γ-1,1-C(sp3)–H activation of aliphatic carboxylic acids: mechanistic pathways, substituent influence on product selectivity, diastereoselectivity, and additive effects

Org. Chem. Front., 2024, 11,6393-6410
DOI: 10.1039/D4QO01451K, Research Article
Jiaoyang Liu, Li-juan Huang, Zeang Sun, Juan Li
DFT calculations were employed to explore the detailed reaction mechanism and the origins of the experimentally observed product, regio-, and diastereoselectivities in the Pd-catalyzed dual-γ-1,1-C(sp3)–H activation of aliphatic carboxylic acids.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A general method for E-selective olefination of acylsilanes with isocyanides via silver catalysis

Org. Chem. Front., 2024, 11,6450-6458
DOI: 10.1039/D4QO01528B, Research Article
Xiu-Xia Liang, Dan-Ni Yang, Xiao-Hui Yan, Peng Wang, Man-Yi Han
A silver-catalyzed olefination reaction between acylsilanes and isocyanides is developed, resulting in E-vinylsilanes with good yields and high stereoselectivities.
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Visible-light-promoted catalytic epoxidation of alkenes under metal-free conditions

Org. Chem. Front., 2024, 11,6437-6443
DOI: 10.1039/D4QO01265H, Research Article
Dabao Tan, Xiaoyan Cai, Lele Zhang, Boyu Liu, Jianbin Zeng, Feiming Li, Zhixiong Cai, Mingqiang Huang, Xiaoping Chen, Shunyou Cai
In this work, we report a method for the synthesis of functionalized epoxy analogues using the synergistic interaction of 4CzIPN and oxygen under visible light stimulation.
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Nickel-catalysed enantioselective cross-electrophile coupling reaction with the retention of the β-fluorine atom

Org. Chem. Front., 2024, 11,6459-6469
DOI: 10.1039/D4QO01555J, Research Article
Xin-Yi Shi, Xueyuan Yan, Xiaodong Tang, Shi-Jing Zhai, Genping Huang, Jun-An Ma, Fa-Guang Zhang
A nickel-catalysed enantioselective reductive cross-coupling reaction of a new monofluoromethyl building block with acid chlorides is developed to give chiral α-monofluoromethyl acyloin derivatives.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Activation of donor–acceptor cyclopropanes under basic conditions: ring opening of 2-(p-siloxyaryl)cyclopropane 1,1-dicarboxylates with nitro compounds and other C-nucleophiles

Org. Chem. Front., 2024, 11,6483-6494
DOI: 10.1039/D4QO01472C, Research Article
Yulia A. Antonova, Andrey A. Tabolin
A new activation mode for donor–acceptor cyclopropanes was proposed and implemented in their reaction with nitro compounds and other common C-nucleophiles.
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Anomalous magnetic behaviour induced by a structural phase transition with anisotropic thermal expansion in a spirodiradical

Org. Chem. Front., 2024, 11,6495-6502
DOI: 10.1039/D4QO01098A, Research Article
Open Access
Takuya Kanetomo, Daigo Matsunaga, Shinichi Ogawa, Masaya Enomoto
A Ge-centred spirodiradical exhibited anomalous magnetic behaviour, influenced by two key structural factors: negative thermal expansion and a structural phase transition.
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Cobalt-catalyzed enantioselective reductive addition of ketimine with cyclopropyl chloride to construct chiral amino esters bearing cyclopropyl fragments

Org. Chem. Front., 2024, 11,6311-6318
DOI: 10.1039/D4QO01474J, Research Article
Jiangtao Hu, Tingting Xia, Xianqing Wu, Hongrui Feng, Jingping Qu, Yifeng Chen
Co-catalyzed asymmetric reductive addition of ketimine with cyclopropyl chloride has been realized to access diverse chiral amino esters bearing cyclopropyl fragments with broad functional group tolerance and excellent enantioselectivities.
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Transition-metal-catalyzed C–Ge coupling reactions

Org. Chem. Front., 2024, 11,6558-6572
DOI: 10.1039/D4QO01637H, Review Article
Jie Ke, Cadmus Du Chen, Li-Qing Ren, Bing Zu, Bin Li, Chuan He
This review covers the development and recent progress in transition-metal-catalyzed C–Ge coupling reactions. The goal is to provide a clear overview of the field, identify current challenges, and inspire further applications in this growing area.
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LiTMP-LiBr complex-induced lateral lithiation and cross ester condensation: direct access to isocoumarins from 2-methoxy o-toluate esters

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01678E, Research Article
Open Access
Mintu Rehman, Sajib Daimary, Rasajna Madhusudhana, Rajendar Goreti
LiTMP-LiBr complex promotes cross-ester coupling of 2-methoxy o-toluate esters to directly yield isocoumarin is demonstrated. Method applied to many natural product precursors including synthesis of (+)- and (−)-lunatinins.
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Enantioselective Addition of 3-hydroxyquinolin-2(1H)-one to Isatin and Pyrazole-4,5-dione Derived Ketimines

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01895H, Research Article
Yue Wei, Guishun Bai, Jiamin Wu, Yi Hua, Tao Zhang, Congyong Yue, Hong Wang, Xiaoze Bao
The enantioselective reactivity of 3-hydroxyquinolin-2(1H)-ones was developed through their addition to isatin and pyrazole-4,5-dione derived ketimines, affording novel architectures featuring multiple natural products scaffolds in high yield with excellent enantioselectivities....
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Folding of a dynamic macrocyclic system to stabilize its cation radical state

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01566E, Research Article
Arnab Dutta, Krzysztof Dzieszkowski, Marco Farinone, Łukasz Orzeł, Krzysztof Kruczała, Monika Kijewska, Miłosz Pawlicki
A precisely designed π-extended system responds to different stimuli by folding the structure, which prevents overoxidation and stabilizes the cation radical.
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Facile single-step synthesis of pentaaryl-substituted pyrano[3,2-b]pyrrol-5(1H)-ones showing aggregation-induced emission

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01600A, Research Article
Yongfeng Wang, Ruijun Chu, Yanxiao Wang, Mengyuan Zhou, Yuan Chen, Cheng Xu, Jingyu Sun, Guodong Yin
A novel class of heterocyclic AIEgens has been synthesized via a multicomponent reaction of isatins, 2,3-diaryl cyclopropenones, and alkyl bromides.
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Recent advances in carbon atom addition for ring-expanding single-atom skeletal editing

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01806K, Review Article
Ting Yuan, Lei Shi
This review focuses on recent advances in carbon atom addition for ring-expanding single-atom skeletal editing.
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Integrating electrocatalysis with biocatalysis for asymmetric synthesis

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01899K, Highlight
Yuqi Lin, Jiage Yu, Ke-Yin Ye
This highlight presents recent advances in asymmetric synthesis that integrate electrocatalysis with biocatalysis and discusses future development directions in this field.
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