This Viewpoint summarizes current shortcomings in direct-to-consumer genetic tests, which often lack clinical utility for consumers, and explains how tests that encompass entire genes and include only genes with well-established risk estimates and medical management guidelines could provide more valuable insight into their disease risk.

In this narrative medicine essay, the sister of a young man with Gardner syndrome reflects on the care her brother received over his nearly three decades of life and offers her observations on several things physicians and other members of health care teams can do to achieve true patient-centered care.