un £1.2 million awarded to improve our understanding of the Sun By www.eurekalert.org Published On :: Fri, 01 May 2020 00:00:00 EDT (Northumbria University ) Researchers from Northumbria University have been awarded £1.2m to help advance our understanding of the Sun and its impact on the planets within our solar system. Full Article
un Free use of Kudos Pro to help researchers keep communicating during pandemic disruption By www.eurekalert.org Published On :: Fri, 01 May 2020 00:00:00 EDT (Kudos Innovations Ltd) Kudos helps researchers maximize reach and visibility of research by opening up Kudos Pro. The platform helps showcase work to a range of target audiences, supporting researchers in fields where conferences have been cancelled -- and those with COVID-19-relevant work that needs rapid communication. Over 2,000 researchers have already signed up. Full Article
un Recipients of 2020 Gruber Cosmology Prize announced By www.eurekalert.org Published On :: Wed, 06 May 2020 00:00:00 EDT (International Astronomical Union) The Gruber Cosmology Prize, which is co-sponsored by the IAU, recognises scientists whose discoveries have driven fundamental advances in our understanding of the Universe. The 2020 prize has been awarded to Lars Hernquist and Volker Springel for their pioneering work on cosmological simulations, which have not only led to their own discoveries, but also become an invaluable resource used widely by other researchers. Full Article
un Hayabusa2's touchdown on Ryugu reveals its surface in stunning detail By www.eurekalert.org Published On :: Thu, 07 May 2020 00:00:00 EDT (American Association for the Advancement of Science) High-resolution images and video were taken by the Japanese space agency's Hayabusa2 spacecraft as it briefly landed to collect samples from Ryugu -- a nearby asteroid that orbits mostly between Earth and Mars -- allowing researchers to get an up-close look at its rocky surface, according to a new report. Full Article
un Highly efficient hydrogen gas production using sunlight, water and hematite By www.eurekalert.org Published On :: Thu, 07 May 2020 00:00:00 EDT (Kobe University) Hydrogen is a possible next generation energy solution, and it can be produced from sunlight and water using photocatalysts. A research group from Kobe University has developed a strategy that greatly increases the amount of hydrogen produced using hematite photocatalysts. In addition to boosting the high efficiency of what is thought to be the world's highest performing photoanode, this strategy will be applied to artificial photosynthesis and solar water-splitting technologies via university-industry collaborations. Full Article
un DDT, other banned pesticides found in Detroit-area black women: BU study By www.eurekalert.org Published On :: Wed, 06 May 2020 00:00:00 EDT (Boston University School of Medicine) A new Boston University School of Public Health (BUSPH) study published in the journal Environmental Research finds detectable levels of DDE (what DDT becomes when metabolized in the body) and other banned organochlorine pesticides (OCPs) in the blood of over 60 percent of a cohort of black women of reproductive age in the Detroit area, with higher levels in women who smoked cigarettes daily, drank more alcohol, and drank more water. Full Article
un Archaeologists verify Florida's Mound Key as location of elusive Spanish fort By www.eurekalert.org Published On :: Thu, 23 Apr 2020 00:00:00 EDT (Florida Museum of Natural History) Florida and Georgia archaeologists have discovered the location of Fort San Antón de Carlos, home of one of the first Jesuit missions in North America. The Spanish fort was built in 1566 in the capital of the Calusa, the most powerful Native American tribe in the region, on present-day Mound Key in the center of Estero Bay on Florida's Gulf Coast. Full Article
un Is planet Earth young or old? By www.eurekalert.org Published On :: Mon, 27 Apr 2020 00:00:00 EDT (World Scientific) New book explores human's endeavours to measure the age of the Earth -- the biblical story, geology's response, Darwin's contribution, Kelvin's cooling Earth model, and modern science. Full Article
un Deformed skulls in an ancient cemetery reveal a multicultural community in transition By www.eurekalert.org Published On :: Wed, 29 Apr 2020 00:00:00 EDT (PLOS) The ancient cemetery of Mözs-Icsei d?l? in present-day Hungary holds clues to a unique community formation during the beginnings of Europe's Migration Period, according to a study published April 29, 2020 in the open-access journal PLOS ONE by Corina Knipper from the Curt-Engelhorn-Center for Archaeometry, Germany, István Koncz, Tivadar Vida from the Eötvös Loránd University, Budapest, Hungary and colleagues. Full Article
un There is no special announcement (19:45 HKT on 03.05.2020) By www.weather.gov.hk Published On :: Sun, 03 May 2020 19:45:05 +0800 There is no special announcement (19:45 HKT on 03.05.2020) Full Article
un Light sensors detect larval pests munching on date palms By www.eurekalert.org Published On :: Wed, 06 May 2020 00:00:00 EDT (King Abdullah University of Science & Technology (KAUST)) Optical fibers wrapped around date palm trunks could help detect this tree's most destructive pest early enough to save it. Full Article
un Minimum energy requirements for microbial communities to live predicted By www.eurekalert.org Published On :: Wed, 06 May 2020 00:00:00 EDT (University of Warwick) A microbial community is a complex, dynamic system composed of hundreds of species and their interactions, they are found in oceans, soil, animal guts and plant roots. Each system feeds the Earth's ecosystem and their own growth, as they each have their own metabolism that underpin biogeochemical cycles. Researchers from the School of Life Sciences at the University of Warwick have produced an extendable thermodynamic model for simulating the dynamics of microbial communities. Full Article
un Arizona State University scientists rewire photosynthesis to fuel our future By www.eurekalert.org Published On :: Wed, 06 May 2020 00:00:00 EDT (Arizona State University) Hydrogen is an essential commodity with over 60 million tons produced globally every year. However over 95 percent of it is made by steam reformation of fossil fuels, a process that is energy intensive and produces carbon dioxide. If we could replace even a part of that with algal biohydrogen that is made via light and water, it would have a substantial impact. Full Article
un University of Tennessee extension forester named 2020 Forester of the Year By www.eurekalert.org Published On :: Thu, 07 May 2020 00:00:00 EDT (University of Tennessee Institute of Agriculture) David Mercker, an Extension forestry specialist with the University of Tennessee Department of Forestry, Wildlife and Fisheries, has been named 2020 Extension Forester of the Year by the Forest Landowners Association (FLA). FLA is a national organization that promotes and protects the interests of private forest landowners and bestows this award annually as determined by its board of directors. Full Article
un Bone proteomics could reveal how long a corpse has been underwater By www.eurekalert.org Published On :: Wed, 29 Apr 2020 00:00:00 EDT (American Chemical Society) When a dead body is found, one of the first things a forensic pathologist tries to do is estimate the time of death. There are several ways to do this, including measuring body temperature or observing insect activity, but these methods don't always work for corpses found in water. Now, researchers are reporting a mouse study in ACS' Journal of Proteome Research showing that certain proteins in bones could be used for this determination. Full Article
un Palestinians say Israel targeting prisoners' bank accounts By news.yahoo.com Published On :: Fri, 08 May 2020 08:26:54 -0400 Palestinian officials said Friday that Israel is forcing banks in the occupied West Bank to close accounts held by the families of prisoners in Israeli jails to prevent the Palestinian Authority from providing stipends to them. Israel has long objected to the Palestinian Authority's payments to the families of prisoners and those killed in the conflict, including militants, saying it rewards terrorism. The Palestinians view the payments as a social safety net for those living under decades of military occupation. Full Article
un A Wisconsin chief justice faced backlash for blaming a county's coronavirus outbreak on meatpacking employees, not 'regular folks' By news.yahoo.com Published On :: Fri, 08 May 2020 00:35:43 -0400 Chief Justice Patience Roggensack faced backlash for her comment, with some people calling it "elitist" to separate meatpackers from "regular folks." Full Article
un Frontier Airlines becomes first U.S. airline to announce passenger temperature checks By news.yahoo.com Published On :: Thu, 07 May 2020 18:36:43 -0400 The budget carrier will begin conducting temperature checks via touchless thermometers on June 1. Passengers have to start wearing masks Friday. Full Article
un Damon Runyon Cancer Research Foundation awards new quantitative biology fellowships By www.eurekalert.org Published On :: Fri, 08 May 2020 00:00:00 EDT (Damon Runyon Cancer Research Foundation) The first class of Damon Runyon Quantitative Biology Fellowship Awardees launched their research in novel directions that may lead to the next breakthroughs in cancer research. Nine brilliant young scientists will apply their quantitative skills to design innovative experiments and interpret massive data sets that may help solve important biological and clinical problems. Full Article
un Life Sciences undergraduates track bird song and coral reef diversity from home By www.imperial.ac.uk Published On :: Wed, 06 May 2020 09:00:00 +0100 As part of the College's move to remote learning, 143 first-year students are taking a series of virtual field courses to investigate biodiversity. Full Article
un Rapid coronavirus test receives major funding By www.imperial.ac.uk Published On :: Wed, 06 May 2020 15:00:00 +0100 A coronavirus test – which aims to deliver rapid results – has received major funding. Full Article
un J-IDEA launches coronavirus pandemic hospital planning tool By www.imperial.ac.uk Published On :: Thu, 07 May 2020 01:00:00 +0100 Imperial's disease outbreak centre J-IDEA has launched a pandemic hospital planning tool to help cope with extreme surges in demand from coronavirus. Full Article
un Sleeter receives funding for historical simulations on diplomacy By www.eurekalert.org Published On :: Fri, 08 May 2020 00:00:00 EDT (George Mason University) Nathan Sleeter, Research Assistant Professor, Roy Rosenzweig Center for History and New Media (RRCHNM), is directing a project in which RRCHNM will create three classroom simulations based on events from the history of diplomacy for secondary education instructors. Full Article
un UCSF expert to offer 'confessions of unfocused researcher' on road to better care By www.eurekalert.org Published On :: Fri, 08 May 2020 00:00:00 EDT (American Geriatrics Society) The American Geriatrics Society (AGS) and AGS Health in Aging Foundation today announced that Alexander K. Smith, MD, MPH, an associate professor of medicine at UCSF and one of geriatrics' most influential rising researchers and advocates, will be honored with the 2020/2021 Thomas and Catherine Yoshikawa Award for Outstanding Scientific Achievement in Clinical Investigation. Full Article
un New Home Office funded report urges greater action for cybercrime victims By www.eurekalert.org Published On :: Wed, 06 May 2020 00:00:00 EDT (University of Portsmouth) The first major UK study into victims of computer misuse crime has exposed the serious harm some victim's experience, as well as barriers to reporting such offences, receiving support, achieving justice and the precarious resources dedicated by the police to cybercrime. Full Article
un Light, sound, action: Extending the life of acoustic waves on microchips By www.eurekalert.org Published On :: Wed, 06 May 2020 00:00:00 EDT (University of Sydney) Data centres and digital information processors are reaching their capacity limits and producing heat. Foundational work here on optical-acoustic microchips opens door to low-heat, low-energy, fast internet. Full Article
un Insights From the National Diabetes Education Program National Diabetes Survey: Opportunities for Diabetes Self-Management Education and Support By spectrum.diabetesjournals.org Published On :: 2017-05-01 Linda J. PiccininoMay 1, 2017; 30:95-100From Research to Practice Full Article
un Fine-Tuning Control: Pattern Management Versus Supplementation: View 1: Pattern Management: an Essential Component of Effective Insulin Management By spectrum.diabetesjournals.org Published On :: 2001-04-01 Jan PearsonApr 1, 2001; 14:Articles Full Article
un A Model of Community-Based Behavioral Intervention for Depression in Diabetes: Program ACTIVE By spectrum.diabetesjournals.org Published On :: 2010-01-01 Mary de GrootJan 1, 2010; 23:18-25From Research to Practice Full Article
un Integrating Depression Care With Diabetes Care in Real-World Settings: Lessons From the Robert Wood Johnson Foundation Diabetes Initiative By spectrum.diabetesjournals.org Published On :: 2007-01-01 Daren AndersonJan 1, 2007; 20:10-16Feature Articles Full Article
un A High Level of Patient Activation Is Observed But Unrelated to Glycemic Control Among Adults With Type 2 Diabetes By spectrum.diabetesjournals.org Published On :: 2010-07-01 Robert MayberryJul 1, 2010; 23:171-176Feature Articles Full Article
un Redesign of a Diabetes System of Care Using an All-or-None Diabetes Bundle to Build Teamwork and Improve Intermediate Outcomes By spectrum.diabetesjournals.org Published On :: 2010-07-01 Frederick J. BloomJul 1, 2010; 23:165-169From Research to Practice Full Article
un Self-Management Goal Setting in a Community Health Center: The Impact of Goal Attainment on Diabetes Outcomes By spectrum.diabetesjournals.org Published On :: 2010-04-01 Daren R. AndersonApr 1, 2010; 23:97-105Feature Articles Full Article
un A Review of Volunteer-Based Peer Support Interventions in Diabetes By spectrum.diabetesjournals.org Published On :: 2011-05-01 Tricia S. TangMay 1, 2011; 24:85-98From Research to Practice/Behavioral Interventions for Diabetes Self-Management Full Article
un Interview-Based Customer Insights in Developing Countries By www8.gsb.columbia.edu Published On :: Wed, 08 Jan 2020 17:00:28 +0000 What are the opportunities and challenges of collecting consumer insights in developing countries—and how can the challenges be overcome? Full Article
un Content creators being left out - Online fun and frolic but no royalties By jamaica-star.com Published On :: Tue, 05 May 2020 05:01:38 -0500 As online parties continue to rise, the question of how artistes and other musicians will get paid from these virtual sessions becomes even more pertinent. During an online forum held by the Jamaica Reggae Industry Association (JaRIA) yesterday... Full Article
un ‘Cool Runnings’ By jamaica-star.com Published On :: Fri, 08 May 2020 05:02:08 -0500 Ja wowed Winter Games in 1988 ... Page 20 Full Article
un Bad Gyal Jade gets boost from Bounty endorsement By jamaica-star.com Published On :: Fri, 08 May 2020 05:01:50 -0500 In an interview with THE STAR last August, up-and-coming artiste Bad Gyal Jade dubbed herself the 'female Kartel'. Drawing comparisons between her style and flow and that of the incarcerated deejay, Jade said the label was a fitting one. Though... Full Article
un Dancers' Paradise: Devon Unruly working hard to expand dance group By jamaica-star.com Published On :: Fri, 08 May 2020 05:01:38 -0500 He's celebrating 10 years of dancing both competitively and in the street, and the co-founder of Unruly Skankaz, Devon Brown, says he is looking to expand the brand. The once three-member male dance group has grown to five, he told THE WEEKEND... Full Article
un What about entertainment? - Industry insider feels sector under-represented in COVID recovery task force By jamaica-star.com Published On :: Fri, 08 May 2020 05:01:40 -0500 Last month, Prime Minister Andrew Holness announced the establishment of an Economic Recovery Task Force, chaired by Finance Minister Dr Nigel Clarke. The multisectoral task force, which is mandated to oversee Jamaica's economic recovery from... Full Article
un COVID-19: Economic Implications for Japan and the United States By www8.gsb.columbia.edu Published On :: Fri, 01 May 2020 00:00:00 -0400 Exploring the economic implications of COVID-19 on Japan and the US. Full Article
un An Uncertain Future: Predicting the Economy After COVID-19 By www8.gsb.columbia.edu Published On :: Wed, 06 May 2020 00:00:00 -0400 Abby Joseph Cohen and Alexis Crow share insights on the economic impact of COVID-19 in a discussion moderated by Pierre Yared. Full Article
un Migration Deals Risk Undermining Global Refugee Protection By feedproxy.google.com Published On :: Fri, 13 Apr 2018 09:53:48 +0000 13 April 2018 Amanda Gray Meral Associate Fellow, International Law Programme @AmandaLouGray While some aspects of agreements like that between the EU and Turkey reflect a genuine effort to cooperate in addressing the needs of refugees, other elements risk undermining the very essence of the global refugee protection regime. 2018-04-13-Lesbos.jpg A boat carrying migrants approaches shore after making the crossing from Turkey to the Greek island of Lesbos in November 2015. Photo: Getty Images. Last month the European Commission proposed that the EU should mobilize the next tranche of funding for Turkey (€3 billion) under the EU–Turkey deal agreed in 2016. The deal is part of a rapidly developing strategy on the part of the EU to improve cooperation on migration issues with countries of origin as well as those through which migrants and refugees transit en route to Europe. Since 2015, the EU has ramped up negotiations, with the New Partnership Framework underpinning arrangements with countries such as Niger, Mali and Ethiopia, and endorsing a memorandum of understanding between Italy and Libya in February 2017.A common thread that runs across all of these deals is their focus on containment in exchange for funding, rather than a principled approach to refugee protection. For example, the EU has committed around €6 billion to Turkey as a contribution towards the cost of humanitarian assistance for the over 3 million Syrian refugees residing there. This funding also operates as an incentive for Turkey to take back all refugees and migrants who have irregularly arrived in Greece via Turkey since the deal entered effect.Similarly, the EU is providing financial support to Libya in exchange for its cooperation in reducing the flow of migrants and refugees towards Europe, while the New Partnership Framework aims to reduce the number of migrants and refugees departing for Europe in exchange for EU aid. While financial incentives geared towards containment do not amount to new policy, with the increasing number of deals being negotiated, the use of such a strategy appears to be both accelerating and becoming more explicit.An effective investment?Implementation of these deals has been hindered by obligations under international law, raising questions not only as to their legality but also their value for money.Under the EU–Turkey deal, refugees arriving in Greece irregularly were to be returned to Turkey, with an equal number of Syrian refugees resettled to Europe in exchange. However, implementation of this aspect of the deal has been limited.Under EU asylum law, Greece is obliged to provide access to asylum procedures for those arriving on its shores. Given that most arrivals from Turkey came from refugee-producing countries (including Syria, Afghanistan and Iraq), an individualized assessment of ‘safe third country’ is required before any possible return to Turkey can take place. This requires a finding that Turkey can guarantee effective access to protection for the individual in question, including protection against refoulement (i.e. forced return to a country where he or she is at risk of serious harm or persecution). By the end March 2018, only 2,164 people had been returned to Turkey.As for Italy, with EU support, under the MOU with Libya it has been training as well as providing funding and logistical support to the Libyan coastguard – including an Italian naval presence in Libyan waters – to intercept boats in the Mediterranean. Given the mounting evidence of abuse of migrants and refugees, whether by Libyan coastguards or inside Libyan detention centres, this raises questions as to whether the support being provided by Italy and the EU amounts to a breach of international law.Despite concerns about the protection risks for refugees, advocates of such deals claim they have the potential to prevent dangerous journeys, saving lives and interrupting the business model of smugglers. Numbers crossing the Mediterranean have indeed dropped since the deals were agreed. However, in Libya it has created an ‘anti-smuggling’ market which, despite leading to a reduction of migration in the short term, may not be sustainable in the long term if it drives conflict between various non-state actors.In the case of the EU–Turkey deal, while it has led to a fall in arrivals to the Greek islands in the first six months of 2017, there is also evidence that smugglers were already adapting their routes, forcing refugees and migrants to travel on the more dangerous central Mediterranean route.For now, at least, these deals appear to have gained significant popular support within the EU. Italy’s approaches in Libya, for example, have been broadly backed by the Italian public – unsurprising given that some polls indicate 50 percent of the Italian population believe migrants to be a threat to public security. However, the drivers of public attitudes towards refugees and migration are complex and, as noted in a policy brief published under the Chatham House–ODI Forum on Refugee and Migration Policy, influenced in part by narratives driven by politicians and the media.What some of these deals have achieved is the significant flow of aid money towards job creation and economic opportunities for refugees, incentivizing policy change in some contexts and producing real benefits for the refugees concerned (while reducing pressures on them to move onwards via dangerous journeys).A prominent example is the Jordan Compact, a 2016 agreement between Jordan, the EU and international financial institutions including the World Bank to improve the livelihoods and education of Syrian refugees inside Jordan. While challenges in its implementation remain, including concerns about labour rights, the Jordan Compact has resulted in real improvements in education and access to the labour market for Syrian refugees. The Jordanian government has made policy concessions on access to work permits for Syrian refugees, removing some of the barriers that prevented refugees accessing jobs, while the EU has committed to ease trade barriers for goods produced in Jordanian factories on condition they hire a percentage of Syrian refugees.Likewise, the EU–Turkey deal’s most successful component has been its financial contribution of €3 billion of aid under the EU Facility for Refugees towards support for the 3.7 million Syrian refugees currently being hosted by Turkey. This includes €1 billion allocated to the Emergency Social Safety Net, described by the European Commission as the ‘largest single humanitarian project in the history of the EU’, directly impacting the livelihoods of some 1.1 million vulnerable refugees.Moving aheadWhile some aspects of these deals reflect a genuine effort to cooperate in addressing the needs of refugees, other elements risk undermining the very essence of the global refugee protection regime.The diplomatic squabble over a proposed refugee ‘swap’ of 1,250 refugees between the US and Australia in February 2017 highlights the danger of refugees becoming bargaining chips. Similarly, the Kenyan government’s announcement that it would close Dadaab refugee camp in late November 2016 cited the EU-Turkey deal as justification. Migration partnerships which emphasise the securing of EU borders against refugee arrivals may diminish the willingness of states in the Global South to continue to host large numbers of refugees.While the positive aspects of such deals deserve acknowledgement, understanding their impact on refugee protection must be given greater attention. This is vital not only to ensure their workability but also to ensure that those countries who spearheaded the creation of the global refugee protection regime do not end up undermining its existence. Full Article
un Forum on Refugee and Migration Policy - Roundtable 3 By feedproxy.google.com Published On :: Fri, 20 Apr 2018 16:00:00 +0000 Invitation Only Research Event 14 May 2018 - 10:00am to 5:30pm Chatham House | 10 St James's Square | London | SW1Y 4LE London This roundtable focuses on the economic dimensions of displacement and migration and brings together an international group of experts from government, international organizations, civil society, research institutes and the private sector. The event was co-hosted with the Overseas Development Institute. Event attributes Chatham House Rule Department/project International Law Programme, Rights, Accountability and Justice, Meeting the Challenge of Forced Displacement Full Article
un Geneva Launch: Protecting Civilians — When is ‘Incidental Harm’ Excessive? By feedproxy.google.com Published On :: Tue, 02 Oct 2018 13:45:01 +0000 Research Event 14 December 2018 - 10:00am to 11:30am Graduate Institute | Chemin Eugène-Rigot 2 | 1202 Geneva | Switzerland Event participants Emanuela-Chiara Gillard, Associate Fellow, International Law Programme, Chatham HouseEzequiel Heffes, Thematic Legal Adviser, Geneva CallSigrid Redse Johansen, Judge Advocate General, The Norwegian Armed ForcesChair: Elizabeth Wilmshurst, Distinguished Fellow, Chatham HouseFurther speakers to be announced. PLEASE NOTE THIS EVENT IS BEING HELD IN GENEVA.There have been large numbers of civilian deaths in the armed conflicts in Yemen and Syria. Is international humanitarian law being ignored? This meeting coincides with the launch of a Chatham House research paper on the incidental harm side of the proportionality assessment which belligerents are legally required to make. The panel at the meeting will consider the types of harm that fall within the scope of proportionality assessments, what constitutes ‘excessive’ harm and measures that belligerents can take to give effect to the rule on proportionality.This event will be followed by a reception. Department/project International Law Programme Chanu Peiris Programme Manager, International Law +44 (0)20 7314 3686 Email Full Article
un The Universal Declaration of Human Rights at 70 By feedproxy.google.com Published On :: Fri, 02 Nov 2018 14:05:01 +0000 Research Event 29 November 2018 - 6:00pm to 7:30pm Chatham House | 10 St James's Square | London | SW1Y 4LE Event participants Phil Bloomer, Executive Director, Business & Human Rights Resource CentreJulie Broome, Director, Ariadne NetworkAllison Corkery, Director of Rights Claiming and Accountability Program, Centre for Economic and Social Rights; Atlantic Fellow for Social and Economic Equity, London School of EconomicsChair: Sonya Sceats, Associate Fellow, International Law Programme The Universal Declaration of Human Rights celebrates its 70th anniversary against a backdrop of fractured global politics and the rise of nationalist forces that reject many of the values the Declaration espouses.What strategies, tools and networks are civil society and other actors developing to adapt to this complex environment for human rights work?And what role does the Declaration and the human rights treaties it has inspired play in shaping responses to current global challenges such as deepening inequality, new forms of technology and climate change? Department/project International Law Programme, Rights, Accountability and Justice Chanu Peiris Programme Manager, International Law +44 (0)20 7314 3686 Email Full Article
un London Launch: Protecting Civilians — When is ‘Incidental Harm’ Excessive? By feedproxy.google.com Published On :: Tue, 06 Nov 2018 18:25:01 +0000 Research Event 14 January 2019 - 5:30pm to 7:00pm Chatham House, London Event participants Emanuela-Chiara Gillard, Associate Fellow, International Law Programme, Chatham HouseEzequiel Heffes, Thematic Legal Adviser, Geneva CallSigrid Redse Johansen, Judge Advocate General, Norwegian Armed ForcesAndrew Murdoch, Legal Director, UK Foreign & Commonwealth OfficeChair: Elizabeth Wilmshurst, Distinguished Fellow, International Law Programme, Chatham House There have been large numbers of civilian deaths in the armed conflicts in Yemen and Syria. Is international humanitarian law being ignored?This meeting marks the London launch of a Chatham House research paper on the incidental harm side of the proportionality assessment which belligerents are legally required to make. The panel at the meeting will consider the types of harm that fall within the scope of proportionality assessments, what constitutes ‘excessive’ harm and measures that belligerents can take to give effect to the rule on proportionality.This event will be followed by a reception. Department/project International Law Programme, Rights, Accountability and Justice Chanu Peiris Programme Manager, International Law +44 (0)20 7314 3686 Email Full Article
un Protection of the Wounded and Medical Care-Givers in Armed Conflict: Is the Law Up to the Job? By feedproxy.google.com Published On :: Wed, 27 Feb 2019 10:21:55 +0000 Research Event 16 May 2019 - 5:30pm to 7:00pm Chatham House | 10 St James's Square | London | SW1Y 4LE Event participants Françoise Bouchet-Saulnier, Legal Director, Médecins Sans FrontièresEzequiel Heffes, Thematic Legal Adviser, Geneva CallRain Liivoja, Associate Professor, University of QueenslandMaciej Polkowski, Head, Health Care in Danger Initiative, International Committee of the Red CrossChair: Elizabeth Wilmshurst, Distinguished Fellow, International Law Programme, Chatham House This meeting, supported by the British Red Cross, is the first in a series of three to commemorate the 70th anniversary of the 1949 Geneva Conventions. The meeting will focus on the protection of the wounded and sick in armed conflict and will also include discussion of challenges to the protection of medical care and of health providers.Attacks on health care personnel and facilities have increased in recent years, as have the instances in which proceedings have been brought against those providing medical care to wounded fighters, including under counter-terrorism measures.The Geneva Conventions and their Protocols give protection to the wounded and sick and to healthcare providers, but is the law adequate? Is the law sufficiently widely known? How can the law be more fully implemented? What particular challenges arise in non-international armed conflicts?This event will be followed by a drinks reception. Department/project International Law Programme, The Limits on War and Preserving the Peace Full Article
un The transcriptional regulator MEIS2 sets up the ground state for palatal osteogenesis in mice [Gene Regulation] By feedproxy.google.com Published On :: 2020-04-17T00:06:05-07:00 Haploinsufficiency of Meis homeobox 2 (MEIS2), encoding a transcriptional regulator, is associated with human cleft palate, and Meis2 inactivation leads to abnormal palate development in mice, implicating MEIS2 functions in palate development. However, its functional mechanisms remain unknown. Here we observed widespread MEIS2 expression in the developing palate in mice. Wnt1Cre-mediated Meis2 inactivation in cranial neural crest cells led to a secondary palate cleft. Importantly, about half of the Wnt1Cre;Meis2f/f mice exhibited a submucous cleft, providing a model for studying palatal bone formation and patterning. Consistent with complete absence of palatal bones, the results from integrative analyses of MEIS2 by ChIP sequencing, RNA-Seq, and an assay for transposase-accessible chromatin sequencing identified key osteogenic genes regulated directly by MEIS2, indicating that it plays a fundamental role in palatal osteogenesis. De novo motif analysis uncovered that the MEIS2-bound regions are highly enriched in binding motifs for several key osteogenic transcription factors, particularly short stature homeobox 2 (SHOX2). Comparative ChIP sequencing analyses revealed genome-wide co-occupancy of MEIS2 and SHOX2 in addition to their colocalization in the developing palate and physical interaction, suggesting that SHOX2 and MEIS2 functionally interact. However, although SHOX2 was required for proper palatal bone formation and was a direct downstream target of MEIS2, Shox2 overexpression failed to rescue the palatal bone defects in a Meis2-mutant background. These results, together with the fact that Meis2 expression is associated with high osteogenic potential and required for chromatin accessibility of osteogenic genes, support a vital function of MEIS2 in setting up a ground state for palatal osteogenesis. Full Article
un The testis-specific LINC component SUN3 is essential for sperm head shaping during mouse spermiogenesis [Cell Biology] By feedproxy.google.com Published On :: 2020-05-08T03:41:14-07:00 Sperm head shaping is a key event in spermiogenesis and is tightly controlled via the acrosome–manchette network. Linker of nucleoskeleton and cytoskeleton (LINC) complexes consist of Sad1 and UNC84 domain–containing (SUN) and Klarsicht/ANC-1/Syne-1 homology (KASH) domain proteins and form conserved nuclear envelope bridges implicated in transducing mechanical forces from the manchette to sculpt sperm nuclei into a hook-like shape. However, the role of LINC complexes in sperm head shaping is still poorly understood. Here we assessed the role of SUN3, a testis-specific LINC component harboring a conserved SUN domain, in spermiogenesis. We show that CRISPR/Cas9-generated Sun3 knockout male mice are infertile, displaying drastically reduced sperm counts and a globozoospermia-like phenotype, including a missing, mislocalized, or fragmented acrosome, as well as multiple defects in sperm flagella. Further examination revealed that the sperm head abnormalities are apparent at step 9 and that the sperm nuclei fail to elongate because of the absence of manchette microtubules and perinuclear rings. These observations indicate that Sun3 deletion likely impairs the ability of the LINC complex to transduce the cytoskeletal force to the nuclear envelope, required for sperm head elongation. We also found that SUN3 interacts with SUN4 in mouse testes and that the level of SUN4 proteins is drastically reduced in Sun3-null mice. Altogether, our results indicate that SUN3 is essential for sperm head shaping and male fertility, providing molecular clues regarding the underlying pathology of the globozoospermia-like phenotype. Full Article