for Methods for converting motor oil into fuel By www.freepatentsonline.com Published On :: Tue, 14 Apr 2015 08:00:00 EDT Methods for converting petroleum based oil into fuel generally include forming a conversion mixture of an alcohol and a base, and adding the conversion mixture to petroleum based oil, such as used motor oil, to form a reaction mixture. The methods can also include adding a high nitrate compound and an amino acid to the reaction mixture and ozonizing the reaction mixture. The result of the methods can include a three phase system in which the bottom phase is asphalt oil, the middle phase is diesel fuel or jet fuel, and the top phase is sulfuric acid. The three phases can be separated to obtain the final diesel fuel or jet fuel product. Full Article
for System for drying a gasification feed By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT Present embodiments include systems for reducing moisture in a solid feed provided to a gasifier. For example, in an embodiment, a feedstock preparation system includes an aspirator having a first inlet for receiving a flow of steam, a second inlet for receiving a flow of a moist gaseous phase from a grinding mechanism configured to grind a solid fuel in the presence of a conveyance gas. The moist gaseous phase includes the conveyance gas and moisture removed from the ground solid fuel. The aspirator also includes an outlet configured to output a reduced pressure flow having the steam and the moist gaseous phase. The aspirator is configured to enhance moisture removal from the ground solid fuel to produce a dry feed of the ground solid fuel. The aspirator discharge is recycled within the process to heat the incoming dry conveyance gas and improve system efficiency. Full Article
for Two-stage reactor and process for conversion of solid biomass material By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT A two-stage reactor is disclosed for the conversion of solid particulate biomass material. The reactor is designed to maximize conversion of the solid biomass material, while limiting excess cracking of primary reaction products. The two-stage reactor comprises a first stage reactor, in which solid biomass material is thermally pyrolyzed to primary reaction products. The primary reaction products are catalytically converted in a second stage reactor. Full Article
for Gasoline fuel composition for improved performance in fuel injected engines By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT A method for improving performance of fuel injectors, and a method for cleaning fuel injectors for an internal combustion engine. The methods include operating the engine on a fuel composition comprising a major amount of fuel and from about 1 to about 200 ppm by weight based on a total weight of the fuel of a reaction product of (i) a hydrocarbyl substituted compound containing at least one tertiary amino group and (ii) a halogen substituted C2-C8 carboxylic acid, ester, amide, or salt thereof, wherein the reaction product as made is substantially devoid of free anion species. Full Article
for Process for demineralising coal By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT A process for demineralizing coal includes the steps of forming a slurry of coal particles in an alkali solution, the slurry containing 10-30% by weight coal, maintaining the slurry at a temperature of 150-250° C. under a pressure sufficient to prevent boiling, separating the slurry into an alkalized coal and a spent alkali leachant, forming an acidified slurry of the alkalized coal, the acidified slurry having a pH of 0.5-1.5, separating the acidified slurry into a coal- containing fraction and a substantially liquid fraction, subjecting the coal-containing fraction to a washing step, particularly a hydrothermal washing step, in which the coal-containing fraction is mixed with water and a polar organic solvent or water and an organic acid to form a mixture and separating the coal from the mixture. The demineralized coal has an ash content of from 0.01-0.2% by weight and can be used a feed to a gas turbine. Full Article
for Method and apparatus for producing synthetic fuels By www.freepatentsonline.com Published On :: Tue, 12 May 2015 08:00:00 EDT For producing synthetic fuels, an educt mixture containing steam and oxygenates, such as methanol and/or dimethyl ether, is converted to olefins on a catalyst in a first process stage, and this olefin mixture then is divided in a separating means into a stream rich in C1-C4 hydrocarbons and a stream rich in C5+ hydrocarbons. The stream rich in C5+ hydrocarbons is divided into a stream rich in C5 and C6 hydrocarbons and a stream rich in C7+ hydrocarbons, wherein the stream rich in C5 and C6 hydrocarbons is at least partly subjected to an etherification with methanol. The ethers thus obtained are admixed to the gasoline product stream. Full Article
for Methods and apparatus for controlling moisture in plant oils and liquid biofuels By www.freepatentsonline.com Published On :: Tue, 12 May 2015 08:00:00 EDT The moisture absorption capacity of biofuels can be more or less 10 times that of fossil diesel oil, causing biofuels to form acids that induce metal corrosion and form deposits in the fuel tank and pipe lines. Methods for removing moisture from stored biofuels and plant oils are described wherein glycerol is used as a solvent to extract the moisture from the bioliquid or oil, comprising the steps of placing the biofuel or oil in fluid contact with glycerol, incubating for a time, and then removing the glycerol. A cellulous ester dialysis or other semi-permeable membrane may be used to prevent the glycerol from contaminating the biofuel while allowing moisture to pass. Crude glycerol produced as a byproduct of biodiesel production may be used in the method of the disclosed invention with good result. Preferred embodiments of apparatus that employ the method of the subject invention are described. Full Article
for Additives for diesel engines By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT The present invention relates to the use of at least 120 ppm of a nitrogen-containing detergent as a diesel fuel additive to improve the performance of a diesel engine having a high pressure fuel system. Full Article
for Use of a reaction product of carboxylic acids with aliphatic polyamines for improving or boosting the separation of water from fuel oils By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Use of a reaction product of saturated or unsaturated aliphatic mono- or polycarboxylic acids with aliphatic polyamines for improving or boosting the separation of water from fuel oils which comprise additives with detergent action. A Fuel additive concentrate comprising the said reaction product, certain additives with detergent action and optionally dehazers, cetane number improvers and solvents or diluents. Full Article
for Methods for producing and using densified biomass products containing pretreated biomass fibers By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A process is provided comprising subjecting a quantity of plant biomass fibers to a pretreatment to cause at least a portion of lignin contained within each fiber to move to an outer surface of said fiber, wherein a quantity of pretreated tacky plant biomass fibers is produced; and densifying the quantity of pretreated tacky plant biomass fibers to produce one or more densified biomass particulates, wherein said biomass fibers are densified without using added binder. Full Article
for COPPER NANOPARTICLES FOR DEGRADATION OF POLLUTANTS By www.freepatentsonline.com Published On :: Thu, 22 Jun 2017 08:00:00 EDT The present invention is directed to a degradation composition, methods and kits for degrading organic pollutants comprising reduced copper based nanoparticles-polymer complex (Cu-NPs) and an oxidant. Full Article
for METHOD FOR REMOVING GLYPHOSATE FROM A SOLUTION By www.freepatentsonline.com Published On :: Thu, 22 Jun 2017 08:00:00 EDT A method includes removing glyphosate from a solution by contacting the solution with a mesoporous inorganic particle having an average pore size of greater than zero and less than about 50 nm, wherein the mesoporous inorganic particle is functionalized with a positively charged moiety selected from ammonium, amine and combinations thereof. Full Article
for METHOD FOR REMOVING GLYPHOSATE FROM A SOLUTION USING FUNCTIONALIZED POLYMERIC NANOPARTICLES By www.freepatentsonline.com Published On :: Thu, 22 Jun 2017 08:00:00 EDT A method for removing glyphosate from a solution by contacting the solution with a polymeric particle including a moiety selected from the group consisting of ammonium, amine and combinations thereof, wherein the moiety is positively charged in the solution. Full Article
for METHOD FOR REDUCING COD OF WASTEWATER WITH IMPROVED UTILIZATION EFFICIENCY OF OZONE By www.freepatentsonline.com Published On :: Thu, 22 Jun 2017 08:00:00 EDT Provided is a method for reducing COD of wastewater with improved utilization efficiency of ozone. The method achieves an objective by adding agents for removing hydroxyl radical scavengers produced by base-catalyzed ozone advanced oxidation to wastewater. The addition of calcium ion, barium ion, etc. to a base-catalyzed ozonation system makes the hydroxyl radical scavengers form precipitates, separated from water and lose the capability of scavenging hydroxyl radicals, thereby enhancing ozone utilization efficiency. Furthermore, calcium ion, barium ion, etc. form precipitates with partial organic acids yielded in the wastewater ozonation and are separated from water, hence diminishing ozone consumption and indirectly improving the ozone utilization efficiency in the wastewater treatment. The present invention can not only significantly enhance the reaction rate and utilization efficiency of ozone, saving reaction time and costs, but also enable complete mineralization of the organic compounds, significantly reducing COD and total phosphorus of wastewater. Full Article
for Biological composite material loaded with magnetic nanoparticles with core-shell structure, the preparation therefore and the application By www.freepatentsonline.com Published On :: Thu, 22 Jun 2017 08:00:00 EDT A preparation method of Bacillus subtilis biological composite material loaded with Fe3O4 magnetic nanoparticles with core-shell structure includes the following steps: 1) preparation of Fe3O4 nanoparticles, 2) preparation of Fe3O4@mSiO2 nanoparticles, 3) preparation of Fe3O4@mSiO2@MANHE nanoparticles; and 4) preparation of Bacillus subtilis@Fe3O4@mSiO2@MANHE composite. Full Article
for Ion Sequestration for Scale Prevention By www.freepatentsonline.com Published On :: Thu, 22 Jun 2017 08:00:00 EDT Cations that can precipitate from an aqueous composition to produce scaling are sequestered by adding a multi-dentate ligand to the aqueous composition. The multi-dentate ligand bonds with the cation to form a non-scaling ionic complex; and the aqueous solution with the ionic complex is used in a process that produces substantially pure water from the aqueous composition, where the cation, absent formation of the ionic complex, is subject to scaling. The pH of the aqueous composition (or a brine including components of the aqueous composition) is then reduced to release the cation from the multi-dentate ligand; and the multi-dentate ligand, after the cation is released, is then reused in a predominantly closed loop. Full Article
for Methods and Apparatus for Creating Particle Derivatives of HDL with Reduced Lipid Content By www.freepatentsonline.com Published On :: Thu, 22 Jun 2017 08:00:00 EDT The present invention is directed to systems, apparatus and methods for creating derivatives of at least one form of HDL without substantially affecting LDL. These derivatives of HDL are particles with reduced lipid content, particularly reduced cholesterol content. These particles have the capacity to bind cholesterol and are administered to a patient to enhance cellular cholesterol efflux and reduce cholesterol levels in cells, tissues, organs, and blood vessels. The present method is useful for treating atherogenic vascular disease and may be combined with other therapies such as statins, inhibitors of cholesterol absorption, niacin, anti-inflammatories, exercise and dietary restriction. Full Article
for DEVICES AND METHODS FOR SAMPLE CHARACTERIZATION By www.freepatentsonline.com Published On :: Thu, 22 Jun 2017 08:00:00 EDT Devices and methods for characterization of analyte mixtures are provided. Some methods described herein include performing enrichment steps on a device before expelling enriched analyte fractions from the device for subsequent analysis. Also included are devices for performing these enrichment steps. Full Article
for ELECTRICAL SENSOR FOR FLUIDS By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT An electrical sensor for sensing electromagnetic properties of process fluids in a dialysis machine or a similar medical device can include a probe for interfacing with the fluids that is made from electronic fabric materials. The electronic fabric probe can include one or more conductors embedded in a non-conductive fabric layer. The electronic fabric probe is accommodated an enclosure which establishes a flow path with respect to the probe to establish fluid contact between the process fluids and the conductors. The conductors can apply or sense current and/or voltage with respect to the fluid. A portion of the electronic fabric probe can be disposed externally of the enclosure to provide electronic communication externally of the enclosure. Full Article
for SYSTEMS AND METHODS FOR MULTIFUNCTIONAL VOLUMETRIC FLUID CONTROL By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Systems and methods for controlling fluid movement and volumes of fluid between a subject and a controlled compliant flow path. The controlled compliant flow path has a means for selectively metering in and metering out fluid from the controlled compliant flow path. An extracorporeal flow path is in fluid communication with the controlled compliant flow path across a semi-permeable membrane where the extracorporeal flow path has a first terminal end and a second terminal end. Full Article
for PACKING SYSTEM AND METHOD FOR CHROMATOGRAPHY COLUMNS By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The invention relates to a method for providing an aseptic chromatography column, said method comprising the steps of: pre-sterilize an empty chromatography column;pre-sterilize a chromatography medium;introducing the pre-sterilized chromatography medium into the pre-sterilized chromatography column using aseptic equipment, thereby providing an aseptic chromatography column comprising chromatography medium. Full Article
for FLUID REMOVAL APPARATUS FOR USE WITH A WEIR TANK By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A separation apparatus that includes a weir tank having a plurality of cells and fluid removal apparatus for each cell to remove the fluid from each cell. The fluid removal apparatus includes an actuator and an extension arm whose movement is caused by the actuator. In addition to the actuator and the extension arm, the fluid removal apparatus includes a plunger attached to the extension arm for selectively engaging a first opening in each cell. Furthermore, a method of removing fluid from the separation apparatus via the fluid removal apparatus. Full Article
for FILTER METHOD FOR FILTERING A FLUID AND FILTERING DEVICE FOR FILTERING A FLUID By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT a filtering method, with which a fluid to be filtered is led through a filter (4), the filter (4) is back-flushed at regular time intervals and a pre-treatment agent is added to the fluid at the entry side of the filter. A process variable which describes the efficiency of the filtration is continuously computed during the filtration, and a metering quantity of the pre-treatment agent is reset on the basis of the values for the process variable or a characteristic values derived from this. Full Article
for PROCESS FOR INHIBITING SCALE FORMATION WITH UV LIGHT By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A process for inhibiting formation of calcium scale in a reverse osmosis desalination membrane during desalination involving desalinating an aqueous salt solution comprising water, sodium chloride, calcium chloride, and sodium bicarbonate with the reverse osmosis desalination membrane, while concurrently irradiating the aqueous salt solution with a UV light source that emits UV light with a wavelength of 250-400 nm. Scale formation is inhibited by treating a salt solution with the UV light in a continuous or a non-continuous process. Full Article
for Systems and arrangements for mitigating environmental damage caused by storm water carried pollution By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A pollution mitigation system is disclosed. The system can include a valve forming a passage the valve installable to form an orifice in a storm drain retention chamber that passes storm water into a conduit of a storm water management system. The valve having a stem connected to a closure member that can plug the orifice. The valve can have a spring loaded actuator that can move the closure member into a closed position. The system can also include a node such as a wireless sensor node or a mote that has sensors, a transceiver, an antenna, a microcontroller, memory, an energy source and at least one output to control movement of the closure member via the preloaded actuator. The node can have an output that provides the stimulus to the preloaded actuator to cause the preloaded actuator to move the closure member to a position that obstructs the passage in response to either the sensor or a transmission from a mobile telephone such as a cell phone or a smartphone. Full Article
for DEVICE AND METHOD FOR TREATING LIQUIDS BY MEANS OF OZONE By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A method for treating contaminated liquids in a flow by ozone, wherein the ozone is fed in gas form into the flow at one point and then is mixed into the flow in stages by mixers following one another in the flow direction, so that an absolute quantity of introduced ozone increases after each mixer until a feed efficiency of more than 95 percent is reached. Full Article
for METHOD TO DISPERSE BYPRODUCTS FORMED IN DILUTION STEAM SYSTEMS By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Disclosed herein are methods for reducing fouling caused by process water present within a water recycling loop of a pyrolysis plant. The process water includes water, a pygas, and in some cases pygas byproducts. Fouling is caused by phase separation and accumulation of materials from the process water on equipment surfaces. The method includes applying a total of about 5 ppm to 500 ppm of one or more antifouling polymers to the process water to form a treated process water. The one or more antifouling polymers are selected from the group consisting of copolymers of unsaturated fatty acids, primary diamines, and acrylic acid; copolymers of methacrylamidopropyl trimethylammonium chloride with acrylic acid and/or acrylamide; copolymers of ethylene glycol and propylene glycol; and blends of two or more thereof. Full Article
for PLANT AND METHOD FOR MELTING AND CLEANING OF SNOW AND ICE By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Plant for melting and cleaning of snow and ice, distinguished in that the plant comprises a means for melting using enthalpy of a water source in order to melt snow and ice, and a means for cleaning for cleaning out the pollution from the water phase that contains the melted snow and ice. Method for melting and cleaning of snow and ice, using the plant according to the invention. Full Article
for Bay Area Activists Protest Peter Thiel's Partnership With Immigration and Customs Enforcement By www.eastbayexpress.com Published On :: Tue, 14 Mar 2017 16:52:00 -0700 'Don’t build technology for Mordor.' On Saturday at Peter Thiel’s San Francisco home overlooking the Bay, protesters demonstrated against a collaboration between Immigration and Customs Enforcement and Palantir Technologies, a data-mining firm that Thiel co-founded. As reported in The Intercept, ICE will be using a new Palantir product called Investigative Case Management to to aid in its expanded deportation mission.… Full Article News & Opinion/News
for Photos from the ANSWER and Indivisible Counter-Protests Against ACT for America's 'March Against Sharia' By www.eastbayexpress.com Published On :: Mon, 12 Jun 2017 08:52:00 -0700 ACT for America, which the Southern Poverty Law Center has designated as an anti-muslim hate group, showed up on Saturday morning in cities nationwide, dubbing its protest a "March Against Sharia." Berkeley was spared, but the group appeared in nearby Santa Clara, and in Roseville, a suburb of Sacramento.… Full Article Blogs/News
for Careful What You Wish For By www.eastbayexpress.com Published On :: Wed, 19 Feb 2020 01:00:00 -0800 Fantasy Island is back. Who wished for that? The people who tell you "there are more tears shed over answered prayers" are people who weren't going to answer your prayers anyway. I was a non-TV watching snob during Fantasy Island's six-year reign on TV, as it impressed upon its viewers the importance of not asking for trouble by wishing for anything.… Full Article Movie Review
for Which Restaurants Are Open For Deliveries and Take-Out? By www.eastbayexpress.com Published On :: Wed, 25 Mar 2020 01:00:00 -0700 The chamber of commerce is maintaining a list of local eateries still open for business. The Oakland Chamber of Commerce has compiled a list of more than 175 Oakland restaurants offering takeout or home delivery. The City of Alameda had a similar idea, and has created a website listing about 85 restaurants.… Full Article Restaurant Review
for SYSTEMS FOR HANDLING MICROFLUIDIC DROPLETS By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The invention generally relates to assemblies for displacing droplets from a vessel that facilitate the collection and transfer of the droplets while minimizing sample loss. In certain aspects, the assembly includes at least one droplet formation module, in which the module is configured to form droplets surrounded by an immiscible fluid. The assembly also includes at least one chamber including an outlet, in which the chamber is configured to receive droplets and an immiscible fluid, and in which the outlet is configured to receive substantially only droplets. The assembly further includes a channel, configured such that the droplet formation module and the chamber are in fluid communication with each other via the channel. In other aspects, the assembly includes a plurality of hollow members, in which the hollow members are channels and in which the members are configured to interact with a vessel. The plurality of hollow members includes a first member configured to expel a fluid immiscible with droplets in the vessel and a second member configured to substantially only droplets from the vessel. The assembly also includes a main channel, in which the second member is in fluid communication with the main channel. The assembly also includes at least one analysis module connected to the main channel. Full Article
for METHODS AND COMPOSITIONS FOR PREDICTING TOBACCO USE By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Provided herein are methods of reliably determining whether or not an individual is a user of tobacco. Full Article
for Process, Apparatus or System and Kit for Classification of Tumor Samples of Unknown and/or Uncertain Origin and Use of Genes of the Group of Biomarkers By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The present invention refers to a process for classifying tumor samples of unknown and/or uncertain primary origin, specifically including the steps of obtaining patterns of biological activity modulation of tumor of unknown and/or uncertain primary origin and comparing them to an specific and unique group of biomarkers which determine the profiles of biological activity modulation of known origin tumors. The present invention belongs to the molecular biology and genetics field. Full Article
for METHODS FOR PREDICTING THE SURVIVAL TIME OF PATIENTS SUFFERING FROM CANCER By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The present invention relates to methods for predicting the survival time of patients suffering from cancer. Said methods are based on the quantification and analysis of the cell free nucleic acids that are present in a sample from the patient and typically include the determination of the level of the mutant nucleic acid which contains a mutation of interest, the calculation of the mutation load for said mutation of interest, the calculation of the DNA integrity index or a combination thereof. Full Article
for METHODS AND COMPOSITIONS RELATING TO FUSIONS OF ALK FOR DIAGNOSING AND TREATING CANCER By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Disclosed are methods and compositions for detecting the presence of a cancer in a subject and assessing the efficacy of treatments for the same. The disclosed method use reverse transcription polymerase chain reaction (RT-PCR) and multiplex polymerase chain reaction techniques as well as Template Exchange Extension Reaction (TEER) to detect the presence of point mutations, truncations, or fusions of anaplastic lymphoma kinase. Full Article
for COMPOSITIONS, METHODS, AND SYSTEMS FOR TISSUE FIXATION By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The present disclosure relates to use of high-concentration aldehyde-based fixatives to fix tissue samples. Aldehyde concentrations are selected that significantly increase rate of diffusion of the fixative solution into the tissue. When combined in the cold-temperature step of a two-temperature fixation, a substantial improvement in the preservation of post-translationally modified proteins is achieved. Full Article
for Enhancing Flow Cytometry Discrimination with Geometric Transformation By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT In flow cytometry, particles (2) can be distinguished between populations (8) by combining n-dimensional parameter data, which may be derived from signal data from a particle, to mathematically achieve numerical results representative of an alteration (48). An alteration may include a rotational alteration, a scaled alteration, or perhaps even a translational alteration. Alterations may enhance separation of data points which may provide real-time classification (49) of signal data corresponding to individual particles into one of at least two populations. Full Article
for Screening Assay for Choice of Prebiotic to Prevent/Treat Gastrointestinal and Systemic Diseases By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT An assay and a method for identifying a prebiotic to treat a subject in need thereof to promote intestinal barrier integrity or to blunt an inflammatory response are provided. Full Article
for NOVEL METHOD FOR DETECTING DETECTION OBJECT IN SAMPLE, AND DETECTION KIT USING SAME By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The present invention relates to a novel method for detecting a detection object in a sample, and a detection device using the same. The detecting method of the present invention uses a “bridge composite” in which gold nanoparticles and an antibody specific to a detection object are coupled in order to induce a sufficient coupling reaction between the antibody and the detection object, thereby improving reactivity. Accordingly, since excellent resolution is provided, the method of the present invention has advantages of enabling accurate concentration measurement of a detection object in a sample, and amplifying a measurement signal. In addition, the method of the present invention can effectively detect small molecules such as hormones, vitamins, etc. having a small molecular weight. Full Article
for MOLECULAR METHODS FOR ASSESSING POST KIDNEY TRANSPLANT COMPLICATIONS By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Methods of screening for expression of an RNA associated with a post-kidney transplant complication include collecting vesicles from urine, isolating vesicle-associated RNA, and analyzing expression patterns. In particular, AIF1, BTN3A3, CCL5, CD48, HAVCR1, or SLC6A6 mRNA expression patterns are analyzed. Full Article
for COMPOSITIONS AND METHODS FOR AUTOIMMUNE DISEASE By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Methods and compositions are described for categorizing and treating autoimmune disease, using single cell network profiling (SCNP), where activation levels of one or more activatable elements are determined in single cells, with or without modulation, to categorize or determine treatment for the autoimmune disease. Full Article
for Assays for the Detection of Anti-TNF Drugs and Autoantibodies By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The present invention provides assays for detecting and measuring the presence or level of anti-TNFα drug therapeutics and autoantibodies in a sample. The present invention is useful for optimizing therapy and monitoring patients receiving anti-TNFα drug therapeutics to detect the presence or level of autoantibodies (e.g., HACA and/or HAHA) against the drug. Full Article
for METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. Several exemplary diseases that can be analyzed using the invention include AML, MDS, and MPN. Full Article
for MATERIALS AND METHODS FOR DIAGNOSIS, PROGNOSIS AND ASSESSMENT OF THERAPEUTIC/PROPHYLACTIC TREATMENT OF PROSTATE CANCER By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A method to detect prostate cancer comprising contacting a sample of prostate cells from the patient with a set of detectably labeled probes under hybridization conditions and determining the presence of chromosomal abnormalities in prostate tumor tissue, PIN (intra-epithelial neoplasia), histologically benign tissue and benign prostatic hyperplasia (BPH); a method to combine immunofluorescence and FISH (IF-FISH) to facilitate the assessment of chromosomal abnormalities; a set of probes; and a kit comprising the set of probes and instructions for diagnosing prostate cancer in a patient. Full Article
for METHODS FOR DIAGNOSIS AND PROGNOSIS OF CANCER By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT We have discovered a protein in humans, herein referred to as collagen like gene (CLG) product (SEQ ID NOS: 12 and 13), that is expressed in human prostate cancer and breast cancer cell lines but not in normal adult, placenta, lung, liver, skeletal muscle, kidney or pancreas tissues. We have also discovered that the level of CLG mRNA expression correlates positively with the metastatic potential of the cancer cell lines tested. Full Article
for METHOD TO IDENTIFY AN APPROACH FOR ACHIEVING MAMMALIAN FERTILIZATION AND TIME PERIOD FOR INSEMINATION By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The diagnosis of male infertility is based predominantly on the results of standard semen analysis for concentration, total motility, progressive motility, volume, pH, viscosity and/or morphology. When sperm enter the female reproductive tract, they must undergo a series of physiological changes, known as capacitation, in order to fertilize an egg. This process involves plasma membrane changes that occur in response to stimuli within the female tract. These changes include removal of sterols and redistribution of the ganglioside GM1. Semen analysis identifies only half the cases of male infertility due to standard semen analysis providing little information on sperm functional competence. Previous data demonstrated that localization of the ganglioside, GM1, identifies sub-populations of sperm capable of undergoing the functional maturation process known as capacitation and tracks strongly with fertility. Full Article
for METHODS FOR MULTIPLEXED DRUG EVALUATION By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Methods for multiplexed delivery of agents to a solid tissue in vivo followed by assessment of efficacy with mass spectrometry are described. Full Article
for EXOSOME AND LIPID BIOMARKERS FOR MEMORY LOSS By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The present invention relates to methods of determining if a subject has an increased risk of suffering from memory impairment. The methods comprise analyzing at least one sample from the subject to determine a value of the subject's exosomal profile or combined biomarker profile (lipids plus exosomal cargo) and comparing the value of the subject's exosomal or combined biomarker profile with the value of a normal exosomal or biomarker profile, respectively. A change in the value of the subject's exosomal or combined biomarker profile, including a change in the subject's exosomal or combined biomarker profile, over normal values is indicative that the subject has an increased risk of suffering from memory impairment compared to a normal individual. Full Article