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Retrospective analysis of laboratory testing in 54 patients with severe- or critical-type 2019 novel coronavirus pneumonia




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The transient receptor potential vanilloid 4 (TRPV4) ion channel mediates protease activated receptor 1 (PAR1)-induced vascular hyperpermeability




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Molecular signatures of tumor progression in myxoid liposarcoma identified by <i>N</i>-glycan mass spectrometry imaging




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Vasoinhibin reduces joint inflammation, bone loss, and the angiogenesis and vasopermeability of the pannus in murine antigen-induced arthritis




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Blocking thrombospondin-1 signaling via CD47 mitigates renal interstitial fibrosis




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Immune dysfunction leads to mortality and organ injury in patients with COVID-19 in China: insights from ERS-COVID-19 study




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MCU-induced mitochondrial calcium uptake promotes mitochondrial biogenesis and colorectal cancer growth




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Erianin, a novel dibenzyl compound in Dendrobium extract, inhibits lung cancer cell growth and migration via calcium/calmodulin-dependent ferroptosis




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Designing of improved drugs for COVID-19: Crystal structure of SARS-CoV-2 main protease M<sup>pro</sup>




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Signal Transduction and Targeted Therapy




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The chromosome-scale genome reveals the evolution and diversification after the recent tetraploidization event in tea plant




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Cadmium isotope fractionation reveals genetic variation in Cd uptake and translocation by <i>Theobroma cacao</i> and role of natural resistance-associated macrophage protein 5 and heavy metal ATPase-family transporters




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MdMYB6 regulates anthocyanin formation in apple both through direct inhibition of the biosynthesis pathway and through substrate removal




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Correction to: A universal pipeline for mobile mRNA detection and insights into heterografting advantages under chilling stress




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MACROD2 deficiency promotes hepatocellular carcinoma growth and metastasis by activating GSK-3β/β-catenin signaling




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19p loss is significantly enriched in older age neuroblastoma patients and correlates with poor prognosis




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Erlotinib sensitivity of <i>MAPK1</i>p.D321N mutation in head and neck squamous cell carcinoma




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Genes and genomes and unnecessary complexity in precision medicine




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Controlling angular dispersions in optical metasurfaces




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Digital synthesis of histological stains using micro-structured and multiplexed virtual staining of label-free tissue




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Author Correction: Particle physics at accelerators in the United States and Asia




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The role of single-cell mechanical behaviour and polarity in driving collective cell migration




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Author Correction: Enhanced energy coupling for indirect-drive fast-ignition fusion targets




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Nature Physics




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Genetic structure in hybrids and progenitors provides insight into processes underlying an invasive cattail (<i>Typha</i> × <i>glauca</i>) hybrid zone




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Considering mutational meltdown as a potential SARS-CoV-2 treatment strategy




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Estimating narrow-sense heritability using family data from admixed populations




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Endostatin and ST2 are predictors of pulmonary hypertension disease course in infants




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Cardiovascular response and sequelae after minimally invasive surfactant therapy in growth-restricted preterm infants




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Implementation of a statewide, multisite fetal tele-echocardiography program: evaluation of more than 1100 fetuses over 9 years




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Hydrocortisone and bronchopulmonary dysplasia: variables associated with response in premature infants




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Communication between neonatologists and parents when prognosis is uncertain




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Epidemiology of thrombosis in Canadian neonatal intensive care units




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AAV-mediated cardiac gene transfer of wild-type desmin in mouse models for recessive desminopathies




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Gene conversion following CRISPR/Cas9 DNA cleavage: an overlooked effect




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Development of a laboratory scalable process for enhancing lentivirus production by transient transfection of HEK293 adherent cultures




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Gene therapy for cardiovascular diseases in China: basic research




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Natural polyphenol assisted delivery of single-strand oligonucleotides by cationic polymers




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CD24Fc protects against viral pneumonia in simian immunodeficiency virus-infected Chinese rhesus monkeys




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Homeostasis and regulation of autoreactive B cells




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Albumin fusion with granulocyte-macrophage colony-stimulating factor acts as an immunotherapy against chronic tuberculosis




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Microwave ablation of primary breast cancer inhibits metastatic progression in model mice via activation of natural killer cells




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The lysine methyltransferase SMYD2 is required for normal lymphocyte development and survival of hematopoietic leukemias




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Evolution and function of interleukin-4 receptor signaling in adaptive immunity and neutrophils




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Extra-adrenal glucocorticoid biosynthesis: implications for autoimmune and inflammatory disorders




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Natural genetic variation in Stim1 creates stroke in the spontaneously hypertensive rat




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Active transcytosis and new opportunities for cancer nanomedicine




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Biomimetic niches reveal the minimal cues to trigger apical lumen formation in single hepatocytes




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Universal chemomechanical design rules for solid-ion conductors to prevent dendrite formation in lithium metal batteries




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Engineering high-energy-density sodium battery anodes for improved cycling with superconcentrated ionic-liquid electrolytes