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Opioid and Hedgehog signalling pathways converge to modulate OA




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Physical therapy better than steroids for knee OA




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Finding a unifying SLE expression signature in a sea of heterogeneity




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Targeting adenosine in SSc




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Evaluation of glucocorticoid-induced TNF receptor (GITR) expression in breast cancer and across multiple tumor types




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Genetic and clinical correlates of entosis in pancreatic ductal adenocarcinoma




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The impact of 2018 ASCO-CAP HER2 testing guidelines on breast cancer HER2 results. An audit of 2132 consecutive cases evaluated by immunohistochemistry and in situ hybridization




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Undifferentiated round cell sarcoma with <i>BCOR</i> internal tandem duplications (ITD) or <i>YWHAE</i> fusions: a clinicopathologic and molecular study




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<i>KRAS</i> amplification in metastatic colon cancer is associated with a history of inflammatory bowel disease and may confer resistance to anti-EGFR therapy




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An analysis of the effect of mu-opioid receptor gene (<i>OPRM1</i>) promoter region DNA methylation on the response of naltrexone treatment of alcohol dependence




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Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment




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10 years of biosimilars: lessons and trends




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Tumours use NETs as physical shields




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Gasdermin D inhibitor protects against sepsis




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Dissecting reprogramming, differentiation and conversion with network biology




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Adult marrow hematopoiesis: a continuum of change




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Reconsidering marrow stem cell cycle status: insights into an actively cycling hematopoietic stem cell population




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Deconvoluting MLL1-dependent pathways in hematopoiesis and leukemogenesis




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Abstracts from the 2nd International Norges Teknisk-Naturvitenskapelige Universitet (NTNU) Symposium: Day 1—Immunotherapy and Hematology




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Coronavirus in context: Scite.ai tracks positive and negative citations for COVID-19 literature




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Coronapod: What use are contact tracing apps? And new hopes for coronavirus drug remdesivir




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Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform




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Use your lab website to make a compelling first impression




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This physicist-turned-economist is modelling the pandemic’s financial fallout




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Editorial Expression of Concern: Exploring the quantum speed limit with computer games




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Picking away at fossilized skeletons




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Composition-dependent thermodynamics of intracellular phase separation




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Publisher Correction: Enhanced ferroelectricity in ultrathin films grown directly on silicon




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RIC-seq for global in situ profiling of RNA–RNA spatial interactions




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Determination of RNA structural diversity and its role in HIV-1 RNA splicing




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Daily briefing: Closest black hole ever discovered was ‘hiding in plain sight’




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Formation of liquid-like cellular organelles depends on their composition




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Podcast: Galileo and the science deniers, and physicists probe the mysterious pion




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Multilayered mechanisms ensure that short chromosomes recombine in meiosis




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Unmasking the Tully Monster: fossils help to tackle a decades-old mystery




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Statin therapy is associated with lower prevalence of gut microbiota dysbiosis




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Basement membrane remodelling regulates mouse embryogenesis




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Molecular design of hypothalamus development




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Identification of type 2 diabetes loci in 433,540 East Asian individuals




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Ancient Andean cities boasted cosmopolitan residents




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Coronavirus blood-clot mystery intensifies




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Publisher Correction: Intensive farming drives long-term shifts in avian community composition




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YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation




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Breaking through the glioblastoma micro-environment via extracellular vesicles




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HSP47 promotes metastasis of breast cancer by interacting with myosin IIA via the unfolded protein response transducer IRE1α




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Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide




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The β-catenin/TCF-4-LINC01278-miR-1258-Smad2/3 axis promotes hepatocellular carcinoma metastasis




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Connectivity map-based drug repositioning of bortezomib to reverse the metastatic effect of GALNT14 in lung cancer




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Blood pressure control and complex health conditions in older adults: impact of recent hypertension management guidelines




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Gamma-glutamyltransferase, arterial remodeling and prehypertension in a healthy population at low cardiometabolic risk