se Safety and efficacy of chimeric antigen receptor T-cell therapy in relapsed/refractory multiple myeloma with renal impairment By feeds.nature.com Published On :: 2020-05-09 Full Article
se Irradiation induces cancer lung metastasis through activation of the cGAS–STING–CCL5 pathway in mesenchymal stromal cells By feeds.nature.com Published On :: 2020-05-07 Full Article
se Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells By feeds.nature.com Published On :: 2020-05-07 Full Article
se WTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2 By feeds.nature.com Published On :: 2020-05-07 Full Article
se LncRNA <i>SNORD3A</i> specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression By feeds.nature.com Published On :: 2020-05-07 Full Article
se NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas By feeds.nature.com Published On :: 2020-05-07 Full Article
se Tumor-selective delivery of antisense oligomers (antimiRs) against oncogenic microRNAs By feeds.nature.com Published On :: 2014-12-18 miRNA-targeted antimiRs conjugated to a peptide with a low pH–induced transmembrane structure (pHLIP) could help treat solid tumors. Full Article
se Dermatophagoides pteronyssinus peptidase 1 (DERP1) By feeds.nature.com Published On :: 2014-12-18 In vitro and rat studies suggest inhibiting the enzymatic activity of house dust mite (HDM) allergens could help treat allergic asthma. Full Article
se HIV reverse transcriptase By feeds.nature.com Published On :: 2014-12-18 In vitro studies have identified indolylarylsulfone derivatives that could help treat HIV infection. Full Article
se Glutathione peroxidase 4 (GPX4) By feeds.nature.com Published On :: 2014-12-18 Mouse studies suggest inhibiting ferroptosis could help treat ischemia/reperfusion injury in the liver and kidney. Full Article
se Angiopoietin 2 (ANG2; ANGPT2); placental growth factor (PGF; PlGF); tissue inhibitor of metalloproteinases 3 (TIMP3) By feeds.nature.com Published On :: 2014-12-18 Mouse studies suggest inhibiting PGF could help treat hypertension. Full Article
se c-jun N-terminal kinase (JNK); MAP kinase 1 (MAPK1; ERK-2); MAPK3 (ERK-1) By feeds.nature.com Published On :: 2014-12-18 In vitro and rodent studies suggest ophiopogonin D could help prevent doxorubicin-induced cardiotoxicity. Full Article
se Topoisomerase II binding protein 1 (TOPBP1) By feeds.nature.com Published On :: 2014-12-18 Mouse and cell culture studies suggest inhibiting TOPBP1 could help treat cancer. Full Article
se Globohexaosylceramide (globo-H); stage-specific embryonic antigen-3 (SSEA-3); SSEA-4 By feeds.nature.com Published On :: 2014-12-18 Mouse studies suggest chemically modified carbohydrate conjugates could be useful as antigens for the development of cancer vaccines. Full Article
se Cyclin dependent kinase 7 (CDK7); v-myc myelocytomatosis viral related oncogene neuroblastoma derived (MYCN; NMYC) By feeds.nature.com Published On :: 2014-12-18 In vitro and mouse studies suggest THZ1, a covalent CDK7 inhibitor, could help treat neuroblastoma and other cancers driven by MYCN and other c-MYC (MYC)-family oncoproteins. Full Article
se Estrogen receptor; LYN kinase (LYN); phosphoinositide 3-kinase (PI3K) By feeds.nature.com Published On :: 2014-12-18 Studies in mice and human samples suggest inhibiting LYN could help treat estrogen receptor–positive breast cancers resistant to anti-estrogen therapy. Full Article
se In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states By feeds.nature.com Published On :: 2020-05-04 Full Article
se FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome By feeds.nature.com Published On :: 2020-05-04 Full Article
se In vivo antitumor activity by dual stromal and tumor-targeted oncolytic measles viruses By feeds.nature.com Published On :: 2020-03-31 Full Article
se Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice By feeds.nature.com Published On :: 2020-04-20 Full Article
se TMB: a promising immune-response biomarker, and potential spearhead in advancing targeted therapy trials By feeds.nature.com Published On :: 2020-04-28 Full Article
se UNC5B mediates G2/M phase arrest of bladder cancer cells by binding to CDC14A and P53 By feeds.nature.com Published On :: 2020-05-06 Full Article
se High-purity orbital angular momentum states from a visible metasurface laser By feeds.nature.com Published On :: 2020-04-27 Full Article
se The rise of integrated quantum photonics By feeds.nature.com Published On :: 2020-04-28 Full Article
se Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization By feeds.nature.com Published On :: 2020-04-23 Full Article
se An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9 By feeds.nature.com Published On :: 2020-04-27 Full Article
se Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy By feeds.nature.com Published On :: 2020-04-27 Full Article
se Nanomedicines based on nanoscale metal-organic frameworks for cancer immunotherapy By feeds.nature.com Published On :: 2020-04-30 Full Article
se Ex vivo pulsed dendritic cell vaccination against cancer By feeds.nature.com Published On :: 2020-05-04 Full Article
se Head-to-head trials in inflammatory bowel disease: past, present and future By feeds.nature.com Published On :: 2020-04-17 Full Article
se Colons or semi-colons: punctuating the regional variation of intestinal microbial–immune interactions By feeds.nature.com Published On :: 2020-04-22 Full Article
se Inducing senescence sensitizes pancreatic tumours to therapies By feeds.nature.com Published On :: 2020-04-28 Full Article
se Author Correction: Management of IBD during the COVID-19 outbreak: resetting clinical priorities By feeds.nature.com Published On :: 2020-05-06 Full Article
se Effects of acute and repeated treatment with methocinnamox, a mu opioid receptor antagonist, on fentanyl self-administration in rhesus monkeys By feeds.nature.com Published On :: 2020-05-06 Full Article
se A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies By feeds.nature.com Published On :: 2020-05-06 Full Article
se Cannabinoid CB<sub>2</sub> receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear By feeds.nature.com Published On :: 2020-05-06 Full Article
se Correction: Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression By feeds.nature.com Published On :: 2020-05-06 Full Article
se Nesfatin-1 puts the brakes on reward-based feeding By feeds.nature.com Published On :: 2020-05-06 Full Article
se Author Correction: Insights into parathyroid hormone secretion By feeds.nature.com Published On :: 2020-04-20 Full Article
se Author Correction: Vitamin lipid nanoparticles enable adoptive macrophage transfer for the treatment of multidrug-resistant bacterial sepsis By feeds.nature.com Published On :: 2020-04-28 Full Article
se SIN List criticism based on misunderstandings By feeds.nature.com Published On :: 2020-05-04 Full Article
se Development of a skin temperature map for dermatomes in individuals with spinal cord injury: a cross-sectional study By feeds.nature.com Published On :: 2020-05-05 Full Article
se Supporting sexual adjustment from the perspective of men living with spinal cord injury By feeds.nature.com Published On :: 2020-05-07 Full Article
se Associations of interruptions to leisure-time sedentary behaviour with symptoms of depression and anxiety By feeds.nature.com Published On :: 2020-05-04 Full Article
se Rodent models of post-traumatic stress disorder: behavioral assessment By feeds.nature.com Published On :: 2020-05-06 Full Article
se Single-cell RNA sequencing reveals the heterogeneity of liver-resident immune cells in human By feeds.nature.com Published On :: 2020-04-28 Full Article
se Efficient generation of mouse models with the prime editing system By feeds.nature.com Published On :: 2020-04-28 Full Article
se Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis By feeds.nature.com Published On :: 2020-04-28 Full Article
se Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing By feeds.nature.com Published On :: 2020-05-04 Full Article
