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Mendelian neurodegenerative disease genes involved in autophagy




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Expert opinion—management of chronic myeloid leukemia after resistance to second-generation tyrosine kinase inhibitors




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Pomalidomide, dexamethasone, and daratumumab in relapsed refractory multiple myeloma after lenalidomide treatment




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An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders




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Parkinson disease and the immune system — associations, mechanisms and therapeutics




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Monogenic small vessel diseases — rare but still important




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Does the presenting phenotype predict survival in ALS–FTD?




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Mining bacteria for biosensors




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History Against Sectarianism, The Telegraph

In December 1947, the annual Indian History Congress was held in Bombay. The President-elect that year was Professor Mohammad Habib of the Aligarh Muslim University, a historian of early medieval India, known especially for his studies of the Delhi Sultanate. From the late 1930s, many students and faculty at AMU had been active supporters of [...]




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Why Authoritarianism is Bad for Science, But Bigotry is Even Worse

There have been many protests against the Citizenship Amendment Bill (now Act), and there will be many more. This piece of legislation strikes at the heart of the Constitution, seeking to make India another country altogether. It is thus that so many people from so many different walks of life have raised their voices against [...]




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Why There is No Team Modi – Because There Can Only Be a Brand Modi, The Telegraph

In December 2018, I was having lunch with an entrepreneur-friend who works closely with the Central Government. The BJP had just lost state elections in Madhya Pradesh, Rajasthan and Chattisgarh, putting three Chief Ministers out of office and out of work. I suggested to the entrepreneur that when the Prime Minister won re-election the following [...]




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Impact of the COVID-19 lockdown on basic science research in ophthalmology: the experience of a highly specialized research facility in France




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Expression of SARS-CoV-2 receptor ACE2 and TMPRSS2 in human primary conjunctival and pterygium cell lines and in mouse cornea




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Design, implementation, and evaluation of a nurse-led intravitreal injection programme for retinal diseases in Singapore




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Generational trends in US opioid-overdose deaths




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Age and generational patterns of overdose death risk from opioids and other drugs




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Possible consequences of the COVID-19 pandemic on the use of biospecimens from cancer biobanks for research in academia and bioindustry




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COVID-19 Research in Brief: 2 May to 8 May, 2020




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Defense Playbook for Campaigns

The 2018 National Defense Strategy (NDS) is predicated on a single organizing principle: America’s military pre-eminence is rapidly eroding. This is not a new concept. For years, experts have warned that the economic and technological advancements of U.S. adversaries, coupled with the 2008 financial crisis and America’s focus on peripheral conflicts, have caused a decline in America’s military dominance. 

In this context, the advances of near-peer competitors such as China and Russia have created plausible “theories of victory” in potential conflicts across Eastern Europe and East Asia. Competitors’ unaddressed improvements in strategic innovation, economic investment, and dual-use technology increases the risk of conflict and strains the U.S. alliance system. It is urgent that the United States reestablish and maintain credible deterrents against these near-peer competitors. After decades of focusing on post-Cold War ‘shaping’ operations, the American military needs to reinvigorate for full spectrum great power competition.

This report is intended as a blueprint on how to begin that process from graduate students at the Belfer Center for Science and International Affairs at Harvard University. Contained inside are 12 memorandums. Each provides a high-level overview and specific recommendations on a key issue of American defense policy. 




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Joseph S. Nye: U.S. and China Need a More Cooperative Security Stance

Joseph S. Nye: U.S. and China Need a More Cooperative Security Stance




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An Interview with Bruce Schneier, Renowned Security Technologist

Bruce Schneier discusses current security technology concerns with The Politic's Eric Wallach.




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Oil's Collapse Is a Geopolitical Reset In Disguise

The world is on the cusp of a geopolitical reset. The global pandemic could well undermine international institutions, reinforce nationalism and spur de-globalization. But far-sighted leadership could also rekindle cooperation, glimmers of which appeared in the G-20’s offer of debt relief for some of the world’s poorest countries, a joint plea from more than 200 former national leaders for a more coordinated pandemic response and an unprecedented multinational pact to arrest the crash in oil markets.  




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Breaking the Ice: How France and the UK Could Reshape a Credible European Defense and Renew the Transatlantic Partnership

History is replete with irony, but rarely more poignantly than in the summer of 2016 when, on 23 June, the UK voted to leave the European Union and the next day, 24 June, the EU published its Global Strategy document asserting its ambition of “strategic autonomy.” Whither Franco-British defense cooperation in such chaotic circumstances? This paper attempts to provide the outline of an answer to that question.




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Cutoff point estimation for serum vitamin D concentrations to predict cardiometabolic risk in Brazilian children




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Promoting healthy lifestyle in Chinese college students: evaluation of a social media-based intervention applying the RE-AIM framework




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Placental expression of leptin: fetal sex-independent relation with human placental growth




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Project on Managing the Atom Seeking Full-Time Research Associate

The Managing the Atom (MTA) project at the Harvard Kennedy School is seeking a full-time Research Associate to support research projects directed by Professor Matthew Bunn on a range of nuclear policy topics including strategic stability and the future of nuclear arms control, reducing the risks of nuclear theft and terrorism worldwide, stemming the spread of nuclear weapons, and addressing key constraints on and risks of nuclear energy. Reporting to the MTA co-principal investigator Prof. Matthew Bunn, the Research Associate will play a major role in researching and writing papers and reports in these areas. 




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Organizational Responses to COVID-19 and Climate Change: A Conversation with Rebecca Henderson

Rebecca Henderson, the John and Natty McArthur University Professor at Harvard University, shared her perspectives on how large organizations are changing in response to the coronavirus pandemic and climate change in the newest episode of “Environmental Insights: Discussions on Policy and Practice from the Harvard Environmental Economics Program.”




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Bruce Schneier on Cybersecurity in the Age of Coronavirus

Is Zoom secure? What about your home computer? Cyber expert Bruce Schneier says that we all need to be aware of the things cyber criminals thrive on during the confusion caused by coronavirus.




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Trump Turned the Death Count Into a Story About Himself

Official figures exclude thousands who have died during the pandemic. To draw the right lessons, the United States needs an accurate tally of the victims.




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HPCA Hosts COP25 Side Event Focused on Reducing GHG Emissions through Carbon Pricing

As negotiators from around the world arrived in Madrid for the second week of the 25th UN Climate Change Conference (COP-25), the Harvard Project on Climate Agreements hosted an official COP side event on Dec. 9 focusing on the potential for reducing greenhouse-gas (GHG) emissions through the use of carbon pricing.




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Comparative Grand Strategy: A Framework and Cases—Book Review

William James reviews Comparative Grand Strategy: A Framework and Cases edited by Thierry Balzacq,  Peter Dombrowski, and Simon Reich (Oxford University Press, 2019).




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COVID-19 Pandemic Accelerates the Rise of Digital Payments

Could using the cash in your pocket have the potential to spread covid-19? That question has rarely appeared in the news, but many governments and leaders in the digital payments industry are wondering how the virus might impact the use of cash. Several countries have already taken drastic measures to limit circulation of bank notes. Could such interventions lead to the end of cash payments?




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U.S. Intervention in Russia-Saudi Impasse Isn't Tenable (Radio)

Meghan L. O’Sullivan, Professor of International Affairs at Harvard’s Kennedy School, former National Security Council advisor, and a Bloomberg Opinion columnist, discusses the oil market plunge, and the Russia-Saudi relationship. Hosted by Lisa Abramowicz and Paul Sweeney.




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How Digital Service Teams are Responding to Covid-19

David Eaves writes that the most significant lesson coming out of the COVID-19 crisis  is the importance of having a digital strategy and a technological infrastructure in place at both the national and local levels.




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Oil Markets Provide a Glimpse of the Post-Pandemic Future

Henry Kissinger warns that many existing domestic and international institutions that have helped govern the past decades will not survive the Covid-19 crisis. He is surely correct.




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Oil's Collapse Is a Geopolitical Reset In Disguise

The world is on the cusp of a geopolitical reset. The global pandemic could well undermine international institutions, reinforce nationalism and spur de-globalization. But far-sighted leadership could also rekindle cooperation, glimmers of which appeared in the G-20’s offer of debt relief for some of the world’s poorest countries, a joint plea from more than 200 former national leaders for a more coordinated pandemic response and an unprecedented multinational pact to arrest the crash in oil markets.  




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What Caused the COVID-19 Testing Deficit?

As the divergent experiences of the US and South Korea show, testing can be the difference between disease containment and catastrophe. Rather than relying on national governments to ensure the rapid development, production, and deployment of diagnostics during outbreaks, the world needs a global coordinating platform.




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Restructuring Argentina’s Private Debt is Essential

Argentina's creditors are being asked to accept a proposal that would reduce their revenue stream but make it sustainable. A responsible resolution will set a positive precedent, not only for Argentina, but for the international financial system as a whole.




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Organizational Responses to COVID-19 and Climate Change: A Conversation with Rebecca Henderson

Rebecca Henderson, the John and Natty McArthur University Professor at Harvard University, shared her perspectives on how large organizations are changing in response to the coronavirus pandemic and climate change in the newest episode of “Environmental Insights: Discussions on Policy and Practice from the Harvard Environmental Economics Program.”




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Bruce Schneier on Cybersecurity in the Age of Coronavirus

Is Zoom secure? What about your home computer? Cyber expert Bruce Schneier says that we all need to be aware of the things cyber criminals thrive on during the confusion caused by coronavirus.




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Trump Turned the Death Count Into a Story About Himself

Official figures exclude thousands who have died during the pandemic. To draw the right lessons, the United States needs an accurate tally of the victims.




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Genome-wide selection and genetic improvement during modern maize breeding




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Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease




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Biallelic mutations in <i>SORD</i> cause a common and potentially treatable hereditary neuropathy with implications for diabetes




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ZBP1 (DAI/DLM-1) promotes osteogenic differentiation while inhibiting adipogenic differentiation in mesenchymal stem cells through a positive feedback loop of Wnt/β-catenin signaling




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Dystrophic calcification and heterotopic ossification in fibrocartilaginous tissues of the spine in diffuse idiopathic skeletal hyperostosis (DISH)




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Ionomycin ameliorates hypophosphatasia via rescuing alkaline phosphatase deficiency-mediated L-type Ca<sup>2+</sup> channel internalization in mesenchymal stem cells




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Bone Research




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Accesibilidad informacional y diversidad funcional en el contexto universitario: el caso de la Universidad Complutense de Madrid

Cuevas-Cerveró, Aurora and Razquín-Zazpe, Pedro and Parra-Valero, Pablo and Barrios-Martínez, Cristina and Gómez-Hernández, José-Antonio . Accesibilidad informacional y diversidad funcional en el contexto universitario: el caso de la Universidad Complutense de Madrid., 2020 In: Competencia en Información y Políticas para Educación Superior: Estudos Hispano-Brasileiros. Universidad Complutense de Madrid, pp. 132-146. [Book chapter]