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[ASAP] Chiral Vanadyl(V) Complexes Enable Efficient Asymmetric Reduction of ß-Ketoamides: Application toward (<italic toggle="yes">S</italic>)-Duloxetine

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00221




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[ASAP] A Condensed, Scalable Synthesis of Racemic Koningic Acid

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00344




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[ASAP] Correction to Specific <italic toggle="yes">Z</italic>-Selectivity in the Oxidative Isomerization of Allyl Ethers to Generate Geometrically Defined <italic toggle="yes">Z</italic>-Enol Ethers Using a Coba

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00990




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[ASAP] Deactivation of Secondary Amine Catalysts via Aldol Reaction–Amine Catalysis under Solvent-Free Conditions

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00665




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[ASAP] Quantitative Kinetic Modeling in Photoresponsive Supramolecular Chemistry: The Case of Water-Soluble Azobenzene/Cyclodextrin Complexes

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00461




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[ASAP] The Synthesis of Functionalized 3-Aryl- and 3-Heteroaryloxazolidin-2-ones and Tetrahydro-3-aryl-1,3-oxazin-2-ones via the Iodocyclocarbamation Reaction: Access to Privileged Chemical Structures and Scope and Limitations of the Method

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.9b03400




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[ASAP] Chemoselective Hydrosilylation of the a,ß-Site Double Bond in a,ß- and a,ß,?,d-Unsaturated Ketones Catalyzed by Macrosteric Borane Promoted by Hexafluoro-2-propanol

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00568




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[ASAP] One-Pot Multicomponent Reaction of Catechols, Ammonium Acetate, and Aldehydes for the Synthesis of Benzoxazole Derivatives Using the Fe(III)–Salen Complex

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00560




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[ASAP] Acylphloroglucinol Derivatives with a Tricyclo-[4.4.1.1<sup>1,4</sup>] Dodecane Skeleton from <italic toggle="yes">Garcinia bracteata</italic> Fruits

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00637




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[ASAP] Zn-Catalyzed Cyanation of Aryl Iodides

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00269




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[ASAP] Accessing Dihydro-1,2-oxazine via Cloke–Wilson-Type Annulation of Cyclopropyl Carbonyls: Application toward the Diastereoselective Synthesis of Pyrrolo[1,2-<italic toggle="yes">b</italic>][1,2]oxazine

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00531




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[ASAP] Application of Pyridinium 1,4-Zwitterionic Thiolates: Synthesis of Benzopyridothiazepines and Benzothiophenes

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00374




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[ASAP] a-Imino Iridium Carbenes from Imidoyl Sulfoxonium Ylides: Application in the One-Step Synthesis of Indoles

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00833




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[ASAP] Palladium-Catalyzed Cascade Cyclization/Dearomatization/Arylation of Alkyne-Containing Phenol-Based Biaryls with Aryl Halides: An Entry to Diversely Functionalized Spirocyclohexadienones

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00710




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[ASAP] Palladium-Catalyzed Synthesis of <italic toggle="yes">N</italic>,<italic toggle="yes">N-</italic>Dimethylanilines via Buchwald–Hartwig Amination of (Hetero)aryl Triflates

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00491




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[ASAP] Earth-Abundant Bimetallic Nanoparticle Catalysts for Aerobic Ammoxidation of Alcohols to Nitriles

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.0c00670




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IL@CQD catalyzed active ester rearrangement for the detection and removal of cyanide ions

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00361A, Paper
Monika Chaudhary, Meenakshi Verma, Pushap Raj, Kailash C. Jena, Narinder Singh
Recognition of cyanide ion with IL@CQDs catalyzed rearranged product.
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Direct Identification of Fish Species by Surface Molecular Transferring

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00510J, Paper
Mingke Shao, Hongyan Bi
With the expanding of the aquatic market and the large quantity of seafood consumption, the issues on safety, traceability and authenticity of seafood are becoming more and more important. Herein,...
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Electrochemical biosensing platforms on the basis of reduced graphene oxide and its composites with Au nanodots

Analyst, 2020, Advance Article
DOI: 10.1039/C9AN02592H, Paper
Liang Mei, Qingyong Zhang, Min Du, Zhiyuan Zeng
rGO and AuNDs-rGO, synthesized by a simple photochemical reduction method, are used for electrochemical biosensors and show good glucose detection.
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Real-time quantification of fusion transcripts with ligase chain reaction by direct ligation of adjacent DNA probes at fusion junction

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00163E, Paper
Fengxia Su, Jianing Ji, Pengbo Zhang, Fangfang Wang, Zhengping Li
A fusion transcript assay is developed based on direct ligation and ligase chain reaction.
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Application of DNA nanodevices for biosensing

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00159G, Minireview
Sinuo Yu, Tianshu Chen, Qianqian Zhang, Mengru Zhou, Xiaoli Zhu
Deoxyribonucleic acid (DNA), the carrier of genetic information in living life, is an essential biomacromolecule in almost all living systems.
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Logic-signal-based Multiplex Detection of MiRNAs with High Tension Hybridization and Multiple Signal Amplification

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00550A, Paper
Yaqin Tang, Xiao He, Rui Yan, Xingming Liu, Yi Zhao, Tingting Wang, Hui Chen, Xuli Feng
MicroRNAs (miRNAs) are crucial regulators of gene expression. The abnormal expression of miRNA is often closely related to many diseases. However, the accurate clinical profiling of miRNA expression remains a...
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Multifunctional red carbon dots: a theranostic platform for magnetic resonance imaging and fluorescence imaging-guided chemodynamic therapy

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00267D, Paper
Wentao Wang, Qicheng Zhang, Ming Zhang, Yihan Liu, Jian Shen, Ninglin Zhou, Xiaoyuan Lu, Changhong Zhao
In recent years, carbon dots (CDs) with red-emitting wavelengths have received increasing attention in cancer therapy and imaging.
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Quantification of protein glycation using vibrational spectroscopy

Analyst, 2020, Advance Article
DOI: 10.1039/C9AN02318F, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Bethan S. McAvan, Aidan P. France, Bruno Bellina, Perdita E. Barran, Royston Goodacre, Andrew J. Doig
FTIR-ATR and Raman spectroscopy can distinguish between glycated and non-glycated proteins.
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Combined Raman and AFM detection of changes in HeLa cervical cancer cells induced by CeO2 nanoparticles – molecular and morphological perspectives

Analyst, 2020, Advance Article
DOI: 10.1039/C9AN02518A, Paper
Mirjana Miletić, Sonja Aškrabić, Jan Rüger, Borislav Vasić, Lela Korićanac, Abdullah Saif Mondol, Jan Dellith, Jürgen Popp, Iwan W. Schie, Zorana Dohčević-Mitrović
Raman and AFM analyses represent a tool for the evaluation of cytotoxic and anti-proliferative effects in cells induced by CeO2 nanoparticles.
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A high-throughput targeted metabolomics method for the quantification of 104 non-polar metabolites in cholesterol, eicosanoid, and phospholipid metabolism: application in the study of a CCl4-induced liver injury mouse model

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00385A, Paper
Mengqi Jia, Zhangxiao Peng, Kaige Yang, Changqing Su, Yan Wang, Chao Yan
Experimental workflow of 104 non-polar metabolites in cholesterol, eicosanoid, and phospholipid metabolisms analysis using UPLC-QqQ-MS.
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Target triggered ultrasensitive electrochemical polychlorinated biphenyl aptasensor based on DNA microcapsules and nonlinear hybridization chain reaction

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00065E, Paper
Ting Han, Shaozhen Wang, Feifan Sheng, Sicheng Wang, Tianyue Dai, Xiaojun Zhang, Guangfeng Wang
In this work, we demonstrated an ultrasensitive detection platform for polychlorinated biphenyls (PCBs) based on DNA microcapsules and a nonlinear hybridization chain reaction (NHCR).
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Rapid and sensitive detection of NGAL for the prediction of acute kidney injury via a polydopamine nanosphere/aptamer nanocomplex coupled with DNase I-assisted recycling amplification

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00474J, Paper
Yiting Hu, Xie-an Yu, Ying Zhang, Ran Zhang, Xuefei Bai, Mi Lu, Jiwei Li, Lifei Gu, Ji-Hua Liu, Bo-Yang Yu, Jiangwei Tian
A rapid and sensitive method for NGAL detection has been developed to predict acute kidney injury and evaluate the protective effect of drug on renal disease.
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Profiling of immune-cancer interactions at the single cell level using microfluidic well array

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00110D, Paper
Honglei Tu, Zhuhao Wu, Yu Xia, Hui Chen, Hang Hu, Zhao Ding, Fuling Zhou, Shishang Guo
Cancer immunotherapy has achieved great success in hematological cancers. However, immune cells are highly heterogeneous population and can vary highly on clonal expansion, migration and function status, making it difficult...
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Isothermal cross-boosting extension–nicking reaction mediated exponential signal amplification for ultrasensitive detection of polynucleotide kinase

Analyst, 2020, Advance Article
DOI: 10.1039/C9AN02569C, Paper
Xiao-Yu Li, Yun-Xi Cui, Yi-Chen Du, An-Na Tang, De-Ming Kong
A novel nucleic acid-based isothermal signal amplification strategy, named cross-boosting extension–nicking reaction (CBENR) is developed and successfully used for rapid and ultrasensitive detection of polynucleotide kinase (PNK) activity.
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Near infrared spectroscopic assessment of loosely and tightly bound cortical bone water

Analyst, 2020, Advance Article
DOI: 10.1039/C9AN02491C, Paper
Ramyasri Ailavajhala, William Querido, Chamith S. Rajapakse, Nancy Pleshko
NIR spectroscopy can differentiate water loosely bound to bone tissue, and tightly bound to either collagen or mineral.
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A portable electrochemiluminescence bipolar electrode array for the visualized sensing of Cas9 activity

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00678E, Paper
Rui Guo, Shanwen Hu, Zonghua Wang
A new type of closed BPE-ECL system based on an Au electric circuit at a portable substrate is designed for the visualized sensing of Cas9 Activity in the CRISPR/Cas9 system.
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Analytical science in neurochemistry

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN90043E, Editorial
Jean-Francois Masson, Parastoo Hashemi, Martyn G. Boutelle
Jean-François Masson, Parastoo Hashemi and Martyn Boutelle introduce the Analyst themed collection on Analytical Science in Neurochemistry.
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Portable surface-enhanced Raman scattering analysis performed with microelectrode-templated silver nanodendrites

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00484G, Paper
Joshua Raveendran, Aristides Docoslis
Using a handheld Raman spectrometer, we demonstrate how silver nanodendritic substrates formed on microelectrode platforms can be used for ultrasensitive detection of target analytes, such as cocaine and melamine. The...
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A polypyrrole-coated eightfold-helical Wells–Dawson POM-based Cu-FKZ framework for enhanced colorimetric sensing

Analyst, 2020, Advance Article
DOI: 10.1039/D0AN00402B, Paper
Qian Li, Mingqi Xu, Xiao Li, Shuxian Li, Liran Hou, Yuhao Chen, Jingquan Sha
A new Wells–Dawson-type CuFKZP2W18-based hybrid compound containing eightfold helical chains is reported, and its CuFKZP2W18/PPy(15%) composite exhibits excellent peroxidase-like catalytic activity.
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A signal cascade amplification strategy based on RT-PCR triggering of G-quadruplex DNAzyme for a novel electrochemical detection of viable Cronobacter sakazakii

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00270D, Paper
Yuanyuan Yuan, Xianyong Wu, Zhanmin Liu, QIqi Ning, Liqiang Fu, Sujuan Wu
Cronobacter sakazakii is an important opportunistic food-borne pathogen, and it can cause severe diseases with main symptoms including neonatal meningitis, necrotizing enterocolitis, and sepsis. For the achievement of practical and...
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iso-μmGene: Isothermal amplification-based portable microfluidic system for simple, reliable and flexibly multiplexed Genetic identification and quantification

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00560F, Paper
Runtao Zhong, Shilin Liu, Guohao Zhang, Mengyu Wang, Yeqing Sun
Simple, reliable and flexibly multiplexed genetic identification and quantification of microbial pathogens is in urgent need for early disease diagnosis and timely treatment. This study presented an isothermal amplification-based portable...
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A traceless clean-up method coupled with gas chromatography and mass spectrometry for analyzing polycyclic aromatic hydrocarbons in complex plant leaf matrices

Analyst, 2020, 145,3266-3273
DOI: 10.1039/D0AN00128G, Paper
Xiangzi Jin, Han Yeong Kaw, Huijie Li, Zhao Wang, Jinhua Zhao, Xiangfan Piao, Donghao Li, Dongri Jin, Miao He
This study developed a traceless clean-up method by combining solid phase extraction (SPE) with gas purge–microsyringe extraction (GP–MSE) to purify sample extracts for the determination of polycyclic aromatic hydrocarbons (PAHs) in plant leaves.
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Accelerated non-crosslinking assembly of DNA-functionalized nanoparticles in alcoholic solvents: for application in the identification of clear liquors

Analyst, 2020, 145,3229-3235
DOI: 10.1039/D0AN00029A, Paper
Luyang Wang, Guoqing Wang, Yali Shi, Lan Zhang, Ran An, Tohru Takarada, Mizuo Maeda, Xingguo Liang
Accelerated aggregation of DNA-functionalized gold nanoparticles is discovered in alcoholic solvents upon adding full-match DNA and is potentially useful for the identification of Baijiu.
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Rapid and accurate identification of marine microbes with single-cell Raman spectroscopy

Analyst, 2020, 145,3297-3305
DOI: 10.1039/C9AN02069A, Paper
Yaoyao Liu, Jingjing Xu, Yi Tao, Teng Fang, Wenbin Du, Anpei Ye
Rapid and accurate identification of individual microorganisms using single-cell Raman spectra combining with one-dimensional convolutional neural networks.
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Label-free analytical performances of a peptide-based QCM biosensor for trypsin

Analyst, 2020, 145,3329-3338
DOI: 10.1039/D0AN00308E, Paper
Zong-Mu Dong, Lu Cheng, Ping Zhang, Guang-Chao Zhao
Peptide chains that can be specifically hydrolyzed by trypsin were synthesized and fabricated with Au NPs-MCA on a QCM electrode for the sensitive quantification of trypsin in a complex matrix.
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A disposable molecularly imprinted electrochemical sensor for the ultra-trace detection of the organophosphorus insecticide phosalone employing monodisperse Pt-doped UiO-66 for signal amplification

Analyst, 2020, 145,3245-3256
DOI: 10.1039/D0AN00278J, Paper
Liping Xu, Jiebin Li, Jiajia Zhang, Junyong Sun, Tian Gan, Yanming Liu
A disposable electrochemical sensor was fabricated based on monodisperse Pt-doped UiO-66 and a mesoporous molecularly imprinted polymer to specifically detect phosalone.
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An SDS-PAGE based method for the quantification of carbon black in biological samples

Analyst, 2020, 145,3370-3375
DOI: 10.1039/D0AN00046A, Paper
Keyang Liu, Bin Wan
Quantification of Carbon Black (CB) in bio-samples was made available through SDS-PAGE gel electrophoresis.
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An ultrasensitive electrochemiluminescence aptasensor for the detection of diethylstilbestrol based on the enhancing mechanism of the metal–organic framework NH2-MIL-125(Ti) in a 3,4,9,10-perylenetetracarboxylic acid/K2S2O8 system

Analyst, 2020, 145,3306-3312
DOI: 10.1039/D0AN00212G, Paper
Jingxian Li, Xueling Shan, Ding Jiang, Zhidong Chen
A novel electrochemiluminescence (ECL) aptasensor based on PTCA/NH2-MIL-125 for the determination of diethylstilbestrol.
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An electrochemical sensor based on enzyme-free recycling amplification for sensitive and specific detection of miRNAs from cancer cells

Analyst, 2020, 145,3353-3358
DOI: 10.1039/D0AN00275E, Paper
Lili Jiang, Yuling Yang, Yuhong Lin, Ziyi Chen, Chao Xing, Chunhua Lu, Huanghao Yang, Shusheng Zhang
A catalyzed hairpin assembly and binding-induced formation of the DNA three-way junction for ultrasensitive electrochemical detection of diverse miRNAs is reported.
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Trace manganese detection via differential pulse cathodic stripping voltammetry using disposable electrodes: additively manufactured nanographite electrochemical sensing platforms

Analyst, 2020, 145,3424-3430
DOI: 10.1039/D0AN00018C, Paper
Open Access
Diego P. Rocha, Christopher W. Foster, Rodrigo A. A. Munoz, Gary A. Buller, Edmund M. Keefe, Craig E. Banks
Additive manufacturing is a promising technology for the rapid and economical fabrication of portable electroanalytical devices.
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An ionic-based carbon dot for enantioselective discrimination of nonaromatic amino alcohols

Analyst, 2020, 145,3395-3400
DOI: 10.1039/D0AN00399A, Paper
Datong Wu, Fei Pan, Li Gao, Yongxin Tao, Yong Kong
An ionic chiral carbon dot was designed and synthesized for the chiral recognition of nonaromatic amino alcohols.
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Time-resolved in situ monitoring of photocatalytic reactions by probe electrospray ionization mass spectrometry

Analyst, 2020, 145,3313-3319
DOI: 10.1039/D0AN00305K, Paper
Zhongbao Han, Xiaoyu Gu, Shirong Wang, Liyan Liu, Ying Wang, Zhen Zhao, Zhan Yu
We report the application of PESI-MS to in situ monitoring of photocatalytic reactions of cationic dyes in suspensions in real-time.
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In situ multiplex detection of serum exosomal microRNAs using an all-in-one biosensor for breast cancer diagnosis

Analyst, 2020, 145,3289-3296
DOI: 10.1039/D0AN00393J, Paper
Huizhen Wang, Dinggeng He, Kejing Wan, Xiaowu Sheng, Hong Cheng, Jin Huang, Xiao Zhou, Xiaoxiao He, Kemin Wang
Herein, a simple all-in-one biosensor based on a DNA three-way junction has been constructed for in situ simultaneous detection of multiple miRNAs by competitive strand displacement.
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Novel ratiometric electrochemical sensor for no-wash detection of fluorene-9-bisphenol based on combining CoN nanoarrays with molecularly imprinted polymers

Analyst, 2020, 145,3320-3328
DOI: 10.1039/D0AN00345J, Paper
Zhaoyi Liu, Yong Zhang, Bing Li, Xiang Ren, Hongmin Ma, Qin Wei
A ratiometric molecularly imprinted polymers electrochemical sensor was fabricated based on the direct electrochemical oxidation of BHPF on CoN nanoarray electrode.
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