Interview with Mohamed Abdel-Wahab, MD, author of Comparison of Balloon-Expandable vs Self-expandable Valves in Patients Undergoing Transcatheter Aortic Valve Replacement: The CHOICE Randomized Clinical Trial

Interview with Dana Dabelea, MD, PhD, author of Prevalence of Type 1 and Type 2 Diabetes Among Children and Adolescents From 2001 to 2009

Interview with Sven Sandin, MSc, author of The Familial Risk of Autism

Interview with Robert N. Weinreb, MD, author of The Pathophysiology and Treatment of Glaucoma

Interview with Mario Castro, MD, author of Effect of Vitamin D₃ on Asthma Treatment Failures in Adults With Symptomatic Asthma and Lower Vitamin D Levels

Interview with Mark G. Kris, MD, author of Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs

Interview with Kim L. Bennell, PhD, author of Effect of Physical Therapy on Pain and Function in Patients With Hip Osteoarthritis: A Randomized Clinical Trial

Interview with Marco Pahor, MD, author of Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial

Interview with Eric M. Mortensen, MD, MSc, author of Association of Azithromycin With Mortality and Cardiovascular Events Among Older Patients Hospitalized With Pneumonia

Interview with Rupert M. Pearse, MD, author of Effect of a Perioperative, Cardiac Output-Guided Hemodynamic Therapy Algorithm on Outcomes Following Major Gastrointestinal Surgery: A Randomized Clinical Trial and Systematic Review

Interview with Christianne L. Roumie, MD, MPH, author of Association Between Intensification of Metformin Treatment With Insulin vs Sulfonylureas and Cardiovascular Events and All-Cause Mortality Among Patients With Diabetes

Interview with Nynne Nyboe Andersen, MD, author of Association Between Tumor Necrosis Factor-α Antagonists and Risk of Cancer in Patients With Inflammatory Bowel Disease

Interview with Claudia S. Robertson, MD, author of Effect of Erythropoietin and Transfusion Threshold on Neurological Recovery After Traumatic Brain Injury: A Randomized Clinical Trial

Interview with Kurt Kroenke, MD, author of Telecare Collaborative Management of Chronic Pain in Primary Care

Interview with Mads E. Jørgensen, MB, author of Time Elapsed After Ischemic Stroke and Risk of Adverse Cardiovascular Events and Mortality Following Elective Noncardiac Surgery

Interview with Mark S. Sulkowski, MD, author of Sofosbuvir and Ribavirin for Hepatitis C in Patients With HIV Coinfection

Interview with Hooman Kamel, MD, author of Perioperative Atrial Fibrillation and the Long-term Risk of Ischemic Stroke

Interview with Harsha Thirumurthy, PhD, author of Effect of Providing Conditional Economic Compensation on Uptake of Voluntary Medical Male Circumcision in Kenya: A Randomized Clinical Trial

Interview with Allison W. Kurian, MD, MSc, author of Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011

Interview with Bradley C. Johnston, PhD, author of Comparison of Weight Loss Among Named Diet Programs in Overweight and Obese Adults: A Meta-analysis

Interview with George R. Buchanan, MD, author of Management of Sickle Cell Disease

Interview with Marc Carrier, MD, MSc, author of Clinical and Safety Outcomes Associated With Treatment of Acute Venous Thromboembolism: A Systematic Review and Meta-analysis

Interview with Miriam Kuppermann, PhD, MPH, author of Effect of Enhanced Information, Values Clarification, and Removal of Financial Barriers on Use of Prenatal Genetic Testing

Interview with Irfan A. Dhalla, MD, MSc, author of Effect of a Postdischarge Virtual Ward on Readmission or Death for High-Risk Patients

Interview with Shelley S. Magill, MD, PhD, author of Prevalence of Antimicrobial Use in US Acute Care Hospitals, May-September 2011

Interview with Ashish K. Jha, MD, MPH, author of Association Between Hospital Conversions to For-Profit Status and Clinical and Economic Outcomes

Interview with Bradley M. Gray, PhD, author of Association Between Imposition of a Maintenance of Certification Requirement and Ambulatory Care-Sensitive Hospitalizations and Health Care Costs

Interview with Seetha Shankaran, MD, author of Effect of Depth and Duration of Cooling on Deaths in the NICU Among Neonates With Hypoxic Ischemic Encephalopathy: A Randomized Clinical Trial

Interview with David M. Nathan, MD, author of Association Between 7 Years of Intensive Treatment of Type 1 Diabetes and Long-term Mortality

Interview with Sheree L. Boulet, DrPH, MPH, author of Trends in Use of and Reproductive Outcomes Associated With Intracytoplasmic Sperm Injection

Interview with Sebastiano Filetti, MD, author of The Natural History of Benign Thyroid Nodules

Interview with Justin B. Dimick, MD, MPH, author of Hospital Credentialing and Privileging of Surgeons: A Potential Safety Blind Spot

Interview with Anny H. Xiang, PhD, author of Association of Maternal Diabetes With Autism in Offspring

Interview with Dale N. Gerding, MD, author of Administration of Spores of Nontoxigenic Clostridium difficile Strain M3 for Prevention of Recurrent C difficile Infection: A Randomized Clinical Trial

Interview with Levi J. Hargrove, PhD, author of Intuitive Control of a Powered Prosthetic Leg During Ambulation: A Randomized Clinical Trial

Interview with Chyke A. Doubeni, MD, MPH, author of Variation in Adenoma Detection Rate and the Lifetime Benefits and Cost of Colorectal Cancer Screening: A Microsimulation Model

Interview with Kevin P. Hill, MD, MHS, author of Medical Marijuana for Treatment of Chronic Pain and Other Medical and Psychiatric Problems: A Clinical Review, and Deepak Cyril D'Souza, MBBS, MD, author of Medical Marijuana: Is the Cart Before the Horse?

Interview with Deborah A. Levine, MD, MPH, author of Trajectory of Cognitive Decline After Incident Stroke

Interview with Francis Couturaud, MD, PhD, author of Six Months vs Extended Oral Anticoagulation After a First Episode of Pulmonary Embolism: The PADIS-PE Randomized Clinical Trial

Interview with Thomas A. Gaziano, MD, MSc, author of Cost-effectiveness of 10-Year Risk Thresholds for Initiation of Statin Therapy for Primary Prevention of Cardiovascular Disease

Interview with Andy Menke, PhD, author of Prevalence of and Trends in Diabetes Among Adults in the United States, 1988-2012

Interview with Ahmedin Jemal, DVM, PhD, author of Temporal Trends in Mortality in the United States, 1969-2013, and J. Michael McGinnis, MD, MPP, author of Mortality Trends and Signs of Health Progress. Also in this episode is a conversation with Christopher J.L. Murray, MD, DPhil, a Professor of Global Health at the University of Washington and Institute Director of the Institute for Health Metrics and Evaluation.

Interview with David A. Asch, MD and Kevin G. Volpp, MD, PhD, authors of Effect of Financial Incentives to Physicians, Patients, or Both on Lipid Levels: A Randomized Clinical Trial

Interview with John H. Sampson, MD, PhD, MHSc, MBA, author of Alternating Electric Fields for the Treatment of Glioblastoma

Constipation is one of the most frequent problems clinicians are asked to deal with. Despite how common it is, constipation is frequently not treated adequately. In this podcast, Arnold Wald, MD, explains a stepwise approach to the management of constipation ranging from very simple measures to the most novel and complicated new medical therapies.

Interview with Saad B. Omer, MBBS, MPH, PhD, author of Association Between Vaccine Refusal and Vaccine-Preventable Diseases in the United States A Review of Measles and Pertussis

Interview with Céline Vetter, PhD, author of Association Between Rotating Night Shift Work and Risk of Coronary Heart Disease Among Women

Interview with Douglas B. White, MD, MAS, author of Prevalence of and Factors Related to Discordance About Prognosis Between Physicians and Surrogate Decision Makers of Critically Ill Patients

Interview with Ezekiel J. Emanuel, MD, PhD, author of Attitudes and Practices of Euthanasia and Physician-Assisted Suicide in the United States, Canada, and Europe

Lyme disease is very common in certain regions of the country and is caused by the spirochete Borrelia bergdorferi. Lyme disease is transmitted by tick bites and in this podcast we review the discovery of Lyme disease, its major clinical features, and how to diagnose and treat it, as told by Dr Alan Steere, Dr Lyndon Hu, and Dr Paul Auerwerter.

Related article: Review of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis