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Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ε4, and the Risk of Late-Onset Alzheimer Disease in African Americans

Interview with Richard Mayeux, MD, MSc, author of Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ε4, and the Risk of Late-Onset Alzheimer Disease in African Americans




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Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay

Interview with Atul A. Gawande, MD, MPH, author of Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay




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Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay

Interview with Atul A. Gawande, MD, MPH, author of Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay




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Prevalence of a Healthy Lifestyle Among Individuals With Cardiovascular Disease in High-, Middle- and Low-Income Countries: The Prospective Urban Rural Epidemiology (PURE) Studyterview

Interview with Koon Teo, MB, PhD, author of Prevalence of a Healthy Lifestyle Among Individuals With Cardiovascular Disease in High-, Middle- and Low-Income Countries: The Prospective Urban Rural Epidemiology (PURE) Study




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Immunogenicity of 2 Doses of Human Papillomavirus Vaccine in Younger Adolescents Versus 3 Doses in Young Women: A Randomized Clinical Trial

Interview with Simon R. M. Dobson, MD, author of Immunogenicity of 2 Doses of Human Papillomavirus Vaccine in Younger Adolescents Versus 3 Doses in Young Women: A Randomized Clinical Trial




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Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration: The Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial

Interview with Emily Y. Chew, MD, author of Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration: The Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial




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Effect of Escitalopram on Mental Stress-Induced Myocardial Ischemia: Results of the REMIT Trial

Interview with Christopher O'Connor, MD, author of Effect of Escitalopram on Mental Stress-Induced Myocardial Ischemia: Results of the REMIT Trial




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Roux-en-Y Gastric Bypass vs Intensive Medical Management for the Control of Type 2 Diabetes, Hypertension, and Hyperlipidemia: The Diabetes Surgery Study Randomized Clinical Trial

Interview with Sayeed Ikramuddin, MD, author of Roux-en-Y Gastric Bypass vs Intensive Medical Management for the Control of Type 2 Diabetes, Hypertension, and Hyperlipidemia: The Diabetes Surgery Study Randomized Clinical Trial




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Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease: The REDUCE Randomized Clinical Trial

Interview with Jonas Rutishauser, MD, author of Short-term vs Conventional Glucocorticoid Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease: The REDUCE Randomized Clinical Trial




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Effect of an Outpatient Antimicrobial Stewardship Intervention on Broad-Spectrum Antibiotic Prescribing by Primary Care Pediatricians: A Randomized Trial

Interview with Jeffrey S. Gerber, MD, PhD, author of Effect of an Outpatient Antimicrobial Stewardship Intervention on Broad-Spectrum Antibiotic Prescribing by Primary Care Pediatricians: A Randomized Trial




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Use of Advanced Treatment Technologies Among Men at Low Risk of Dying From Prostate Cancer

Interview with Brent K. Hollenbeck, MD, MS, author of Use of Advanced Treatment Technologies Among Men at Low Risk of Dying From Prostate Cancer




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Effect of Home Blood Pressure Telemonitoring and Pharmacist Management on Blood Pressure Control: A Cluster Randomized Clinical Trial

Interview with Karen L. Margolis, MD, MPH, author of Effect of Home Blood Pressure Telemonitoring and Pharmacist Management on Blood Pressure Control: A Cluster Randomized Clinical Trial




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Geographic Variation in Cardiovascular Procedure Use Among Medicare Fee-for-Service vs Medicare Advantage Beneficiaries

Interview with Daniel D. Matlock, MD, MPH, author of Geographic Variation in Cardiovascular Procedure Use Among Medicare Fee-for-Service vs Medicare Advantage Beneficiaries




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Association Between Duration of Overall and Abdominal Obesity Beginning in Young Adulthood and Coronary Artery Calcification in Middle Age

Interview with Jared P. Reis, PhD, author of Association Between Duration of Overall and Abdominal Obesity Beginning in Young Adulthood and Coronary Artery Calcification in Middle Age




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Views of US Physicians About Controlling Health Care Costs

Interview with Jon C. Tilburt, MD, MPH, author of Views of US Physicians About Controlling Health Care Costs




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Concurrent Naltrexone and Prolonged Exposure Therapy for Patients With Comorbid Alcohol Dependence and PTSD: A Randomized Clinical Trial

Interview with Edna B. Foa, PhD, author of Concurrent Naltrexone and Prolonged Exposure Therapy for Patients With Comorbid Alcohol Dependence and PTSD: A Randomized Clinical Trial




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Improved Blood Pressure Control Associated With a Large-Scale Hypertension Program

Interview with Marc G. Jaffe, MD, author of Improved Blood Pressure Control Associated With a Large-Scale Hypertension Program




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Sofosbuvir and Ribavirin for Hepatitis C Genotype 1 in Patients With Unfavorable Treatment Characteristics: A Randomized Clinical Trial

Interview with Anthony S. Fauci, MD, author of Sofosbuvir and Ribavirin for Hepatitis C Genotype 1 in Patients With Unfavorable Treatment Characteristics: A Randomized Clinical Trial




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Effects of a Fixed-Dose Combination Strategy on Adherence and Risk Factors in Patients With or at High Risk of CVD: The UMPIRE Randomized Clinical Trial

Interview with Simon Thom, MB,BS, MD, author of Effects of a Fixed-Dose Combination Strategy on Adherence and Risk Factors in Patients With or at High Risk of CVD: The UMPIRE Randomized Clinical Trial




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Industry-Sponsored Clinical Trials in Emerging Markets: Time to Review the Terms of Engagement

Interview with Stephen MacMahon, DSc, FMedSci, author of Industry-Sponsored Clinical Trials in Emerging Markets: Time to Review the Terms of Engagement




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Effects of Individual Physician-Level and Practice-Level Financial Incentives on Hypertension Care

Interview with Laura A. Petersen, MD, MPH, author of Effects of Individual Physician-Level and Practice-Level Financial Incentives on Hypertension Care




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Chronic Care Management for Dependence on Alcohol and Other Drugs

Interview with Richard Saitz, MD, MPH, author of Chronic Care Management for Dependence on Alcohol and Other Drugs




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Mobility Limitation in the Older Patient: A Clinical Review

Interview with Cynthia J. Brown, MD, author of Mobility Limitation in the Older Patient: A Clinical Review




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Association of National Initiatives to Improve Cardiac Arrest Management With Rates of Bystander Intervention and Patient Survival After Out-of-Hospital Cardiac Arrest

Interview with Christian Torp-Pedersen, MD, DSc, author of Association of National Initiatives to Improve Cardiac Arrest Management With Rates of Bystander Intervention and Patient Survival After Out-of-Hospital Cardiac Arrest




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World Medical Association's Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects

Howard Bauchner, MD interviews Ramin W. Parsa-Parsi, MD, MPH and Heikki Pälve, MD, PhD about the World Medical Association's Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects




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Association Between Influenza Vaccination and Cardiovascular Outcomes in High-Risk Patients: A Meta-analysis

Interview with Jacob A. Udell, MD, MPH, FRCPC, author of Association Between Influenza Vaccination and Cardiovascular Outcomes in High-Risk Patients: A Meta-analysis




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Association of Testosterone Therapy With Mortality, Myocardial Infarction, and Stroke in Men With Low Testosterone Levels

Interview with Michael Ho, MD, PhD, author of Association of Testosterone Therapy With Mortality, Myocardial Infarction, and Stroke in Men With Low Testosterone Levels




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Complications of Daytime Elective Laparoscopic Cholecystectomies Performed by Surgeons Who Operated the Night Before

Interview with Christopher Vinden, MD, author of Complications of Daytime Elective Laparoscopic Cholecystectomies Performed by Surgeons Who Operated the Night Before




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The Anatomy of Health Care in the United States

Interview with Hamilton Moses III, MD, author of The Anatomy of Health Care in the United States




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Outcomes Following Transcatheter Aortic Valve Replacement in the United States

Interview with Michael J. Mack, MD, author of Outcomes Following Transcatheter Aortic Valve Replacement in the United States




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JEffect of Weight Reduction and Cardiometabolic Risk Factor Management on Symptom Burden and Severity in Patients With Atrial Fibrillation: A Randomized Clinical Trial

Interview with Prashanthan Sanders, MBBS, PhD, author of Effect of Weight Reduction and Cardiometabolic Risk Factor Management on Symptom Burden and Severity in Patients With Atrial Fibrillation: A Randomized Clinical Trial




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Rates of Medical Errors and Preventable Adverse Events Among Hospitalized Children Following Implementation of a Resident Handoff Bundle

Interview with Amy J. Starmer, MD, MPH, author of Rates of Medical Errors and Preventable Adverse Events Among Hospitalized Children Following Implementation of a Resident Handoff Bundle




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Effect of Communication Skills Training for Residents and Nurse Practitioners on Quality of Communication With Patients With Serious Illness: A Randomized Trial

Interview with J. Randall Curtis, MD, MPH, author of Effect of Communication Skills Training for Residents and Nurse Practitioners on Quality of Communication With Patients With Serious Illness: A Randomized Trial




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Calcium-Channel Blocker-Clarithromycin Drug Interactions and Acute Kidney Injury

Interview with Amit X. Garg, MD, PhD, author of Calcium-Channel Blocker-Clarithromycin Drug Interactions and Acute Kidney Injury




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Long-term Drug Treatment for Obesity: A Systematic and Clinical Review

Interview with Susan Z. Yanovski, MD, author of Long-term Drug Treatment for Obesity: A Systematic and Clinical Review




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Calcium Density of Coronary Artery Plaque and Risk of Incident Cardiovascular Events

Interview with Michael H. Criqui, MD, MPH, author of Calcium Density of Coronary Artery Plaque and Risk of Incident Cardiovascular Events




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Effect of 3 to 5 Years of Scheduled CEA and CT Follow-up to Detect Recurrence of Colorectal Cancer: The FACS Randomized Clinical Trial

Interview with John N. Primrose, MD, FRCS, author of Effect of 3 to 5 Years of Scheduled CEA and CT Follow-up to Detect Recurrence of Colorectal Cancer: The FACS Randomized Clinical Trial




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Clinical Trial Evidence Supporting FDA Approval of Novel Therapeutic Agents, 2005-2012

Interview with Joseph S. Ross, MD, MHS, author of Clinical Trial Evidence Supporting FDA Approval of Novel Therapeutic Agents, 2005-2012




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Blood Pressure Trajectories in Early Adulthood and Subclinical Atherosclerosis in Middle Age

Interview with Norrina B. Allen, PhD, MPH, author of Blood Pressure Trajectories in Early Adulthood and Subclinical Atherosclerosis in Middle Age




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Surgical Site Infections Following Ambulatory Surgery Procedures

Interview with Claudia A. Steiner, MD, MPH, author of Surgical Site Infections Following Ambulatory Surgery Procedures




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Association Between Participation in a Multipayer Medical Home Intervention and Changes in Quality, Utilization, and Costs of Care

Interview with Mark W. Friedberg, MD, MPP, author of Association Between Participation in a Multipayer Medical Home Intervention and Changes in Quality, Utilization, and Costs of Care




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Warfarin, Kidney Dysfunction, and Outcomes Following Acute Myocardial Infarction in Patients With Atrial Fibrillation

Interview with Juan Jesús Carrero, PhD(Pharm and Med), author of Warfarin, Kidney Dysfunction, and Outcomes Following Acute Myocardial Infarction in Patients With Atrial Fibrillation




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Comparison of 2 Transvaginal Surgical Approaches and Perioperative Behavioral Therapy for Apical Vaginal Prolapse

Interview with Matthew D. Barber, MD, MHS, author of Comparison of 2 Transvaginal Surgical Approaches and Perioperative Behavioral Therapy for Apical Vaginal Prolapse




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Psychiatric Diagnoses and Psychoactive Medication Use Among Nonsurgical Critically Ill Patients Receiving Mechanical Ventilation

Interview with Derek C. Angus, MD, MPH, author of Psychiatric Diagnoses and Psychoactive Medication Use Among Nonsurgical Critically Ill Patients Receiving Mechanical Ventilation




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Screening for Prostate Cancer With the Prostate-Specific Antigen Test: A Review of Current Evidence

Interview with Michael J. Barry, MD, author of Screening for Prostate Cancer With the Prostate-Specific Antigen Test: A Review of Current Evidence




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Interview with Henry Waxman (D, Calif), retiring from Congress after 20 terms.

Interview with Henry Waxman (D, Calif) who is retiring from Congress after 20 terms.




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A Systematic Assessment of Benefits and Risks to Guide Breast Cancer Screening Decisions

Interview with Nancy L. Keating, MD, MPH, author of A Systematic Assessment of Benefits and Risks to Guide Breast Cancer Screening Decisions




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Fibromyalgia: A Clinical Review

Interview with Daniel J. Clauw, MD, author of Fibromyalgia: A Clinical Review




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Comparison of Balloon-Expandable vs Self-expandable Valves in Patients Undergoing Transcatheter Aortic Valve Replacement: The CHOICE Randomized Clinical Trial

Interview with Mohamed Abdel-Wahab, MD, author of Comparison of Balloon-Expandable vs Self-expandable Valves in Patients Undergoing Transcatheter Aortic Valve Replacement: The CHOICE Randomized Clinical Trial




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Door-to-Needle Times for Tissue Plasminogen Activator Administration and Clinical Outcomes in Acute Ischemic Stroke Before and After a Quality Improvement Initiative

Interview with Gregg C. Fonarow, MD, author of Door-to-Needle Times for Tissue Plasminogen Activator Administration and Clinical Outcomes in Acute Ischemic Stroke Before and After a Quality Improvement Initiative