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Medical and legalized marijuana in Colorado

Interview with Larry Wolk, MD, MSPH, chief medical officer for the Colorado Department of Public Health, about medical and legalized marijuana in Colorado.




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Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs

Interview with Mark G. Kris, MD, author of Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs




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Effect of Physical Therapy on Pain and Function in Patients With Hip Osteoarthritis: A Randomized Clinical Trial

Interview with Kim L. Bennell, PhD, author of Effect of Physical Therapy on Pain and Function in Patients With Hip Osteoarthritis: A Randomized Clinical Trial




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Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial

Interview with Marco Pahor, MD, author of Effect of Structured Physical Activity on Prevention of Major Mobility Disability in Older Adults: The LIFE Study Randomized Clinical Trial




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Association of Azithromycin With Mortality and Cardiovascular Events Among Older Patients Hospitalized With Pneumoniaew

Interview with Eric M. Mortensen, MD, MSc, author of Association of Azithromycin With Mortality and Cardiovascular Events Among Older Patients Hospitalized With Pneumonia




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Effect of a Perioperative, Cardiac Output-Guided Hemodynamic Therapy Algorithm on Outcomes Following Major Gastrointestinal Surgery: A Randomized Clinical Trial and Systematic Review

Interview with Rupert M. Pearse, MD, author of Effect of a Perioperative, Cardiac Output-Guided Hemodynamic Therapy Algorithm on Outcomes Following Major Gastrointestinal Surgery: A Randomized Clinical Trial and Systematic Review




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Association Between Intensification of Metformin Treatment With Insulin vs Sulfonylureas and Cardiovascular Events and All-Cause Mortality Among Patients With Diabetes

Interview with Christianne L. Roumie, MD, MPH, author of Association Between Intensification of Metformin Treatment With Insulin vs Sulfonylureas and Cardiovascular Events and All-Cause Mortality Among Patients With Diabetes




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Association Between Tumor Necrosis Factor-α Antagonists and Risk of Cancer in Patients With Inflammatory Bowel Disease

Interview with Nynne Nyboe Andersen, MD, author of Association Between Tumor Necrosis Factor-α Antagonists and Risk of Cancer in Patients With Inflammatory Bowel Disease




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Breast Cancer Screening Using Tomosynthesis in Combination With Digital Mammography

Interview with Sarah M. Friedewald, MD, author of Breast Cancer Screening Using Tomosynthesis in Combination With Digital Mammography




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of Effect of Erythropoietin and Transfusion Threshold on Neurological Recovery After Traumatic Brain Injury: A Randomized Clinical Trial

Interview with Claudia S. Robertson, MD, author of Effect of Erythropoietin and Transfusion Threshold on Neurological Recovery After Traumatic Brain Injury: A Randomized Clinical Trial




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Transcatheter Aortic Valve Implantation in Failed Bioprosthetic Surgical Valves

Interview with Danny Dvir, MD, author of Transcatheter Aortic Valve Implantation in Failed Bioprosthetic Surgical Valves




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Telecare Collaborative Management of Chronic Pain in Primary Care

Interview with Kurt Kroenke, MD, author of Telecare Collaborative Management of Chronic Pain in Primary Care




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Time Elapsed After Ischemic Stroke and Risk of Adverse Cardiovascular Events and Mortality Following Elective Noncardiac Surgery

Interview with Mads E. Jørgensen, MB, author of Time Elapsed After Ischemic Stroke and Risk of Adverse Cardiovascular Events and Mortality Following Elective Noncardiac Surgery




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Screening and Brief Intervention for Drug Use in Primary Care

Interview with Richard Saitz, MD, MPH, author of Screening and Brief Intervention for Drug Use in Primary Care




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Does This Man With Lower Urinary Tract Symptoms Have Bladder Outlet Obstruction? The Rational Clinical Examination: A Systematic Review

Interview with Karen A. D'Silva, MD, MS, author of Does This Man With Lower Urinary Tract Symptoms Have Bladder Outlet Obstruction? The Rational Clinical Examination: A Systematic Review




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Sustained Care Intervention and Postdischarge Smoking Cessation Among Hospitalized Adults

Interview with Nancy A. Rigotti, MD, author of Sustained Care Intervention and Postdischarge Smoking Cessation Among Hospitalized Adults




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Effect of Providing Conditional Economic Compensation on Uptake of Voluntary Medical Male Circumcision in Kenya: A Randomized Clinical Trial

Interview with Harsha Thirumurthy, PhD, author of Effect of Providing Conditional Economic Compensation on Uptake of Voluntary Medical Male Circumcision in Kenya: A Randomized Clinical Trial




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Collaborative Care for Adolescents With Depression in Primary Care

Interview with Laura P. Richardson, MD, MPH, author of Collaborative Care for Adolescents With Depression in Primary Care




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Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011

Interview with Allison W. Kurian, MD, MSc, author of Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011




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Clinical and Safety Outcomes Associated With Treatment of Acute Venous Thromboembolism: A Systematic Review and Meta-analysis

Interview with Marc Carrier, MD, MSc, author of Clinical and Safety Outcomes Associated With Treatment of Acute Venous Thromboembolism: A Systematic Review and Meta-analysis




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Effect of Enhanced Information, Values Clarification, and Removal of Financial Barriers on Use of Prenatal Genetic Testing

Interview with Miriam Kuppermann, PhD, MPH, author of Effect of Enhanced Information, Values Clarification, and Removal of Financial Barriers on Use of Prenatal Genetic Testing




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Acupuncture for Chronic Knee Pain: A Randomized Clinical Trial

Interview with Kim L. Bennell, PhD, author of Acupuncture for Chronic Knee Pain: A Randomized Clinical Trial




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Prevalence of Antimicrobial Use in US Acute Care Hospitals, May-September 2011

Interview with Shelley S. Magill, MD, PhD, author of Prevalence of Antimicrobial Use in US Acute Care Hospitals, May-September 2011




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Obstetric Quality Indicators and Morbidity

Interview with Elizabeth A Howell, MD, MPP, author of Durability of Benefits of an Outpatient Antimicrobial Stewardship Intervention After Discontinuation of Audit and Feedback




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For-Profit Status and Clinical and Economic Outcomes

Interview with Ashish K. Jha, MD, MPH, author of Association Between Hospital Conversions to For-Profit Status and Clinical and Economic Outcomes




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Frozen Fecal Microbiota for C difficile Infection

Interview with Ilan Youngster, MD, MMSc, author of Oral, Capsulized, Frozen Fecal Microbiota Transplantation for Relapsing Clostridium difficile Infection




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Medicare Hospice Benefit and Poor-Prognosis Cancer

Interview with Ziad Obermeyer, MD, MPhil, author of Association Between the Medicare Hospice Benefit and Health Care Utilization and Costs for Patients With Poor-Prognosis Cancer




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Inpatient STEMI and Treatment and Clinical Outcomes

Interview with George A. Stouffer, MD, author of Association of Inpatient vs Outpatient Onset of ST-Elevation Myocardial Infarction With Treatment and Clinical Outcomes




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Medical Liability and Reform

Interview with Michelle M. Mello, JD, PhD, MPhil, author of The Medical Liability Climate and Prospects for Reform




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CAD Screening in Patients With Diabetes Mellitus

Interview with Joseph B. Muhlestein, MD, author of Effect of Screening for Coronary Artery Disease Using CT Angiography on Mortality and Cardiac Events in High-Risk Patients With Diabetes




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Imposition of a MOC Requirement and Outcomes of Care

Interview with Bradley M. Gray, PhD, author of Association Between Imposition of a Maintenance of Certification Requirement and Ambulatory Care-Sensitive Hospitalizations and Health Care Costs




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Glycemic Index, Cardiovascular Disease, and Insulin Sensitivity

Interview with Frank M. Sacks, MD, author of Effects of High vs Low Glycemic Index of Dietary Carbohydrate on Cardiovascular Disease Risk Factors and Insulin Sensitivity




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Breast Cancer Stage at Diagnosis and Survival

Interview with Steven A. Narod, MD, FRCPC, author of Differences in Breast Cancer Stage at Diagnosis and Cancer-Specific Survival by Race and Ethnicity in the United States




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MR/Ultrasound Fusion Biopsy for Prostate Cancer

Interview with Peter A. Pinto, MD, author of Comparison of MR/Ultrasound Fusion-Guided Biopsy With Ultrasound-Guided Biopsy for the Diagnosis of Prostate Cancer




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Measuring Surgical Outcomes

Interview with Donald M. Berwick, MD, MPP, author of Measuring Surgical Outcomes for Improvement: Was Codman Wrong?




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Outcomes After Transcatheter Aortic Valve Replacement

Interview with David R. Holmes Jr, MD, author of Clinical Outcomes at 1 Year Following Transcatheter Aortic Valve Replacement




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Oral Steroids for Acute Sciatica Due to Herniated Lumbar Disk

Interview with Harley Goldberg, DO, author of Oral Steroids for Acute Radiculopathy Due to a Herniated Lumbar Disk: A Randomized Clinical Trial




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Subclinical Thyroid Dysfunction and Fracture Risk

Interview with Anne R. Cappola, MD, ScM, author of Subclinical Thyroid Dysfunction and Fracture Risk: A Meta-analysis




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Outcomes for ACOs vs Traditional Medicare Fee for Service

Interview with Patrick H. Conway, MD, MSc, author of Association of Pioneer Accountable Care Organizations vs Traditional Medicare Fee for Service With Spending, Utilization, and Patient Experience




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Why the Americans With Disabilities Act Matters for Genetics

Interview with Ellen Wright Clayton, MD, JD , author of Why the Americans With Disabilities Act Matters for Genetics




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Lifetime Benefits and Costs of Colorectal Cancer Screening

Interview with Chyke A. Doubeni, MD, MPH, author of Variation in Adenoma Detection Rate and the Lifetime Benefits and Cost of Colorectal Cancer Screening: A Microsimulation Model




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Antibiotics vs Appendectomy for Uncomplicated Appendicitis Treatment

JAMA Topic Review: Edward Livingston, MD, FACS, AGAF, Deputy Editor of JAMA, explores how the study by Paulina Salminen, MD, PhD, supports treating appendicitis without surgery




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ICD Use Among Medicare Patients After Acute MI

Interview with Tracy Y. Wang, MD, MHS, MSc, author of Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Acute Myocardial Infarction




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Medical Marijuana for Treatment of Chronic Pain and Other Problems

Interview with Kevin P. Hill, MD, MHS, author of Medical Marijuana for Treatment of Chronic Pain and Other Medical and Psychiatric Problems: A Clinical Review, and Deepak Cyril D'Souza, MBBS, MD, author of Medical Marijuana: Is the Cart Before the Horse?




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Cardiac Survival After Bystander and First-Responder CPR Intervention

Interview with Carolina Malta Hansen, MD, author of Association of Bystander and First-Responder Intervention With Survival After Out-of-Hospital Cardiac Arrest in North Carolina, 2010-2013




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Mortality, Hospitalizations, and Expenditures for the Medicare Population

Interview with Harlan M. Krumholz, MD, SM, author of Mortality, Hospitalizations, and Expenditures for the Medicare Population Aged 65 Years or Older, 1999-2013




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Donald M. Berwick Reflects on Medicare at 50

Medicare at 50: Reflections From Former CMS Administrator Donald M. Berwick, MD




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Medicare and Medicaid at 50 Years

Interview with Drew Altman, PhD and William Frist, MD, authors of Medicare and Medicaid at 50 Years: Perspectives of Beneficiaries, Health Care Professionals and Institutions, and Policy Makers





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Sex Differences in Academic Rank in US Medical Schools

Interview with Anupam Jena, MD, PhD, author of Sex Differences in Academic Rank in US Medical Schools in 2014