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Nanowires for energy applications / edited by Sudha Mokkapati, Chennupati Jagadish

Barker Library - TK7874.85.N37 2018




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Semiconductor Nanotechnology: Advances in Information and Energy Processing and Storage / edited by Stephen M. Goodnick, Anatoli Korkin, Robert Nemanich

Online Resource




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Applied nanotechnology: the conversion of research results to products / Jeremy J. Ramsden, University of Buckingham, Buckingham, UK

Online Resource




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Nanotechnology-based targeted drug delivery systems for lung cancer / edited by Prashant Kesharwani

Barker Library - T174.7.N37347 2019




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Nanotechnology applications in dairy science: packaging, processing, and preservation / edited by Lohith Kumar Dasarahally-Huligowda, Megh R. Goyal, Hafiz Ansar Rasul Suleria

Online Resource




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School closures and the online preparedness of children during the COVID-19 pandemic [electronic resource] / by Marc Frenette, Kristyn Frank, and Zechuan Deng

[Ottawa] : Statistics Canada = Statistique Canada, 2020




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COVID-19 pandemic [electronic resource]: school closures and the online preparedness of children / by Marc Frenette, Kristyn Frank and Zechuan Deng

[Ottawa] : Statistics Canada = Statistique Canada, 2020




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Asymmetric copper-catalyzed conjugate additions of organometallic reagents in syntheses of natural compounds and pharmaceuticals

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00278J, Review Article
Denisa Vargová, Ivana Nemethova, Radovan Sebesta
Stereoselective synthesis of complex molecular structures is needed in medicine as well as in crop-protection. Copper-catalyzed 1,4-additions of organometallic reagents is a robust C-C bond formation strategy applicable in a...
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Synthesis of Biaryl Ketones by Arylation of Weinreb Amides with Functionalized Grignard Reagents under Thermodynamic Control vs. Kinetic Control of N,N-Boc2-Amides

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00813C, Communication
Guangchen Li, Michal Szostak
A highly efficient method for chemoselective synthesis of biaryl ketones by arylation of Weinreb amides (N-methoxy-N- methylamides) with functionalized Grignard reagents is reported. This protocol offers rapid entry to functionalized...
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Highly Z-selective synthesis of 1,3-oxathiol-2-ylidenes and 4-methylene-oxazolidine-2-thiones via atom-specific 5-exo-dig cyclization of propargyl alcohol with isothiocyanate

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00083C, Paper
S. Antony Savarimuthu, D. G. Leo Prakash, S. Augustine Thomas, Thirumanavelan Gandhi, Mrinal K. Bera
The Z-selectivity observed in imine and alkene motifs after 5-exo-dig cyclization of propargyl alcohol and isothiocyanate is rare in the literature and this selectivity can be attributed to electronic and steric factors of the imine and alkene motif respectively.
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Selenium-promoted electrophilic cyclization of arylpropiolamides: synthesis of 3-organoselenyl spiro[4,5]trienones

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00609B, Paper
Ana Maria S. Recchi, Pedro H. P. Rosa, Davi F. Back, Gilson Zeni
A synthetic approach to regioselective synthesis of 3-organochalcogenyl spiro[4,5]trienones and 3-organochalcogenyl[4,5]triene-2,6-diones is described through the reaction of arylpropiolamides with an electrophilic chalcogen source.
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A modular approach to the bisbenzylisoquinoline alkaloids tetrandrine and isotetrandrine

Org. Biomol. Chem., 2020, 18,3047-3068
DOI: 10.1039/D0OB00078G, Paper
Ramona Schütz, Maximilian Meixner, Iris Antes, Franz Bracher
A modular short-step synthesis of the bisbenzylisoquinoline alkaloids tetrandrine and isotetrandrine was developed employing N-acyl-Pictet–Spengler reaction and Ullman diaryl ether synthesis as central steps.
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Diversity oriented multi-component reaction (DOS–MCR) approach to access natural product analogues: regio- and chemo-selective synthesis of polyheterocyclic scaffolds via one-pot cascade reactions

Org. Biomol. Chem., 2020, 18,3082-3092
DOI: 10.1039/D0OB00368A, Paper
Lakshmanan Palanivel, Vasuki Gnanasambandam
Skeletally diverse and complex polyheterocyclic hybrid scaffolds have been accessed via one-pot three-component reaction by exploiting the build/couple/pair strategy of diversity oriented synthesis.
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The silver catalyzed direct C–H functionalization of quinones with dialkyl amides

Org. Biomol. Chem., 2020, 18,3027-3031
DOI: 10.1039/D0OB00323A, Communication
Sakthivel Pandaram, Adarsh Krishna T. P., Andivelu Ilangovan
A novel and efficient strategy for the direct C–H amidoalkylation of quinones via a radical pathway has been achieved using readily available alkyl amides and an AgNO3-TBHP catalyst system. This is the first ever example of the synthesis of novel amidoquinone derivatives.
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Stereoselective preparation of P,axial-stereogenic allenyl bisphosphine oxides via chirality-transfer

Org. Biomol. Chem., 2020, 18,3017-3021
DOI: 10.1039/D0OB00390E, Communication
Mao-Ran Qiu, Hong-Xing Zheng, Jing-Jing Ye, Bing-Xia Yan, Chang-Qiu Zhao, Qiang Li
Allenyl bisphosphine oxides having variable chirality were prepared in high dr, which was controlled by chiral carbon and phorphorus.
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Regio- and stereoselective synthesis of 1,4-enynes by iron-catalysed Suzuki–Miyaura coupling of propargyl electrophiles under ligand-free conditions

Org. Biomol. Chem., 2020, 18,3022-3026
DOI: 10.1039/D0OB00357C, Communication
Ryosuke Agata, Siming Lu, Hiroshi Matsuda, Katsuhiro Isozaki, Masaharu Nakamura
The first iron-catalysed cross coupling of propargyl electrophiles with lithium alkenylborates has been developed.
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Photochemical rearrangement of diarylethenes: synthesis of functionalized phenanthrenes

Org. Biomol. Chem., 2020, 18,3098-3103
DOI: 10.1039/D0OB00296H, Paper
A. V. Zakharov, A. V. Yadykov, A. G. Lvov, E. A. Mitina, V. Z. Shirinian
The photocyclization of diarylethenes bearing naphthalene units was explored and a convenient protocol for the synthesis of functionalized phenanthrenes was proposed.
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Metal-free cascade reactions of aziridines with arylalkynes and aryldiazoniums: facile access to arylazopyrrolines

Org. Biomol. Chem., 2020, 18,3149-3157
DOI: 10.1039/D0OB00346H, Paper
Jing Rong, Hao Jiang, Sijing Wang, Zhenni Su, Huiyan Wang, Chuanzhou Tao
A novel and facile approach to synthesize arylazopyrroline scaffolds via metal-free cascade reactions of aziridines with arylalkynes and aryldiazoniums has been developed, providing access to a variety of 4-arylazo-2-pyrrolines in a highly concise fashion.
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Catalyst and solvent switched divergent C–H functionalization: oxidative annulation of N-aryl substituted quinazolin-4-amine with alkynes

Org. Biomol. Chem., 2020, 18,3032-3037
DOI: 10.1039/D0OB00318B, Communication
Siddi Ramulu Meesa, Praveen Kumar Naikawadi, Kishan Gugulothu, K. Shiva Kumar
Catalyst and solvent controlled ortho/peri site-selective oxidative annulation of C–H bonds of N-aryl substituted quinazolin-4-amines with internal alkynes.
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Biochemical characterisation of an α1,4 galactosyltransferase from Neisseria weaveri for the synthesis of α1,4-linked galactosides

Org. Biomol. Chem., 2020, 18,3142-3148
DOI: 10.1039/D0OB00407C, Paper
Kun Huang, Andrea Marchesi, Kristian Hollingsworth, Peter Both, Ashley P. Mattey, Edward Pallister, Helene Ledru, Simon J. Charnock, M. Carmen Galan, W. Bruce Turnbull, Fabio Parmeggiani, Sabine L. Flitsch
A new α1,4 galactosyltransferase has been characterised and used for the synthesis of natural and non-natural cell surface trisaccharide antigens.
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Rh(III)-Catalyzed regioselective C4 alkylation of indoles with allylic alcohols: direct access to β-indolyl ketones

Org. Biomol. Chem., 2020, 18,3038-3042
DOI: 10.1039/D0OB00396D, Communication
Changduo Pan, Gao Huang, Yujia Shan, Yiting Li, Jin-Tao Yu
A Rh(III)-catalyzed direct C4 alkylation of indoles with allylic alcohols to access β-indolyl ketones was developed.
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Synthesis, radiolabelling and initial biological characterisation of 18F-labelled xanthine derivatives for PET imaging of Eph receptors

Org. Biomol. Chem., 2020, 18,3104-3116
DOI: 10.1039/D0OB00391C, Paper
Marc Pretze, Christin Neuber, Elisa Kinski, Birgit Belter, Martin Köckerling, Amedeo Caflisch, Jörg Steinbach, Jens Pietzsch, Constantin Mamat
Two new fluorine-18-labelled xanthine derivatives with high binding affinity were synthesised as PET-radioligand candidates for Eph receptors.
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Enantioselective synthesis of chiral α-alkynylated thiazolidones by tandem S-addition/acetalization of alkynyl imines

Org. Biomol. Chem., 2020, 18,3117-3124
DOI: 10.1039/D0OB00365D, Paper
Mei-Xin Wang, Juan Liu, Zhen Liu, Yingcheng Wang, Qi-Qiong Yang, Wenyu Shan, Yu-Hua Deng, Zhihui Shao
A SPINOL-CPA catalyzed asymmetric [2 + 3]-annulation of in situ generated alkynyl imines and 1,4-dithiane-2,5-diol has been developed to afford enantiopure α-alkynylated thiazolidones.
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Pseudo-enantiomeric carbohydrate-based N-heterocyclic carbenes as promising chiral ligands for enantiotopic discrimination

Org. Biomol. Chem., 2020, 18,3012-3016
DOI: 10.1039/D0OB00155D, Communication
Alexander S. Henderson, John F. Bower, M. Carmen Galan
The practical synthesis of pseudo-enantiomeric carbohydrate-based NHC–Rh complexes bearing C1 or C3 sterically differentiated positions is reported. We show that steric bulk at either C1 or C3 leads to enantiotopic discrimination in the hydrosilylation of acetophenone.
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Synthesis and aggregation behaviour of single-chain, 1,32-alkyl-branched bis(phosphocholines) – part 2: lateral chain length triggers self-assembling from sheets to fibres to vesicles

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00534G, Paper
Kai Gruhle, Max Tuchtenhagen, Sindy Müller, Gerd Hause, Annette Meister, Simon Drescher
The synthesis of six single-chain, alkyl-branched bolalipids and first investigations of the lyotropic behaviour of these lipids are reported.
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Half-sandwich (η5-Cp*)Rh(III) complexes of pyrazolated organo-sulfur/selenium/tellurium ligands: efficient catalysts for base/solvent free C–N coupling of chloroarenes under aerobic conditions

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00538J, Paper
Charu Sharma, Avinash Kumar Srivastava, Kamal Nayan Sharma, Raj Kumar Joshi
Three new Rh(III) complexes of organochalcogen (S/Se/Te) ligands were synthesized and along with a co-catalyst Cu(OAc)2, used for the base/solvent free catalysis of Buchwald type C–N coupling of amines and aryl chlorides under aerobic conditions.
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Photocatalytic xanthate-based radical addition/cyclization reaction sequence toward 2-biphenyl isocyanides: synthesis of 6-alkylated phenanthridines

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00136H, Communication
Pedro López-Mendoza, Luis D. Miranda
A photocatalytic xanthate-based radical addition/cyclization reaction cascade toward 2-biphenylisocyanides is described as a practical and modular approach to 6-alkylated phenanthridines.
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Study on the ArI-catalyzed intramolecular oxy-cyclization of 2-alkenylbenzamides to benzoiminolactones

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00612B, Communication
Huixia Liu, Xiaojun Deng, Xie Huang, Nan Ji, Wei He
A metal-free synthetic method toward the preparation of benzoiminolactones through oxy-cyclization of 2-alkenylbenzamides mediated by a catalyst/oxidant (ArI/mCPBA) system was developed.
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Electrochemical synthesis of selenyl-dihydrofurans via anodic selenofunctionalization of allyl-naphthol/phenol derivatives and their anti-Alzheimer activity

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00629G, Communication
Marcos R. Scheide, Alex R. Schneider, Guilherme A. M. Jardim, Guilherme M. Martins, Daniele C. Durigon, Sumbal Saba, Jamal Rafique, Antonio L. Braga
Herein, we report an eco-friendly, electrosynthetic approach for the intramolecular oxyselenylation of allyl-naphthol/phenol derivatives.
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Visible light promoted continuous flow photocyclization of 1,2-diketones

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00532K, Paper
Francesco Secci, Stefania Porcu, Alberto Luridiana, Angelo Frongia, Pier Carlo Ricci
A continuous flow Norrish–Yang photocyclization of 1,2-diketones has been developed and applied to the synthesis of functionalized 2-hydroxycyclobutanones, under blue light irradiation.
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N-Hydroxy peptides: solid-phase synthesis and β-sheet propensity

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00664E, Paper
Matthew P. Sarnowski, Juan R. Del Valle
Backbone amide hydroxylation of peptide strands enhances β-hairpin folding.
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Ni(II)-Catalyzed vinylic C–H functionalization of 2-acetamido-3-arylacrylates to access isotetronic acids

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00557F, Paper
Biswajit Roy, Eshani Das, Avijit Roy, Dipakranjan Mal
A ligand-free Ni(II)-catalyzed cascade annulation reaction for the synthesis of 4-aryl-substituted isotetronic acids from 2-acetamido-3-arylacrylates via vinylic C–H functionalization is reported.
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Acylation of oxindoles using methyl/phenyl esters via mixed Claisen condensation – An access to 3-alkylideneoxindoles

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00789G, Communication
Ramdas Sreedharan, Purushothaman Rajeshwaran, Pradeep Kumar Reddy Panyam, Saurabh Yadav, C. M. Nagaraja, THIRUMANAVELAN GANDHI
Predominantly, aggressive acid chlorides and stoichiometric coupling reagents are employed in the acylating process for synthesizing carbonyl tethered heterocycles. Herein, we report simple acyl sources, viz. methyl and phenyl esters...
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The key entity of a DCAR agonist, phosphatidylinositol mannoside Ac1PIM1: its synthesis and immunomodulatory function

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/C9OB02724F, Communication
Yohei Arai, Shota Torigoe, Takanori Matsumaru, Sho Yamasaki, Yukari Fujimoto
We achieved the first synthesis of phosphatidylinositol mannoside Ac1PIM1, and a very potent agonist of an innate immune receptor DCAR is demonstrated.
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A laccase-catalysed tyrosine click reaction

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00650E, Communication
Shinichi Sato, Keita Nakane, Hiroyuki Nakamura
The tyrosine click reaction of peptides/proteins with the tyrosine modification reagent, N-methyl luminol, was catalysed by a laccase in the presence of molecular oxygen (O2) at 37 °C.
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Electrochemically enabled functionalization of indoles or anilines to synthesis of hexafluoroisopropoxy indole and anilinederivatives

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00157K, Communication
Zu-yu Mo, Xin-Yu Wang, Yu-zhen Zhang, Li Yang, Hai-Tao Tang, Ying-Ming Pan
An environmentally benign electrochemically enabled site-selective functionalization of indole or aniline derivatives with hexafluoroisopropanol in the presence of tetrabutyl ammonium hexafluorophosphate as redox catalyst and electrolyte was demonstrated in this...
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Copper(I)/Ganphos catalysis: enantioselective synthesis of diverse spirooxindoles using iminoesters and alkyl substituted methyleneindolinones

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00546K, Paper
Hao Cui, Ke Li, Yue Wang, Manman Song, Congcong Wang, Donghui Wei, Er-Qing Li, Zheng Duan, François Mathey
A copper/Ganphos-catalyzed asymmetric 1,3-dipolar cycloaddition of glycine iminoesters with alkyl substituted 3-methylene-2-oxindoles is described, producing the spiro[pyrrolidin-3,3'-oxindole]s in good yields with high ee.
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Blue emissive dimethylmethylene-bridged triphenylamine derivatives appending cross-linkable groups

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00622J, Paper
Kangyu Zhou, Hongfei Pan, Yongjie Zhang, Houchen Wang, Xiaofei Dong, Xiangkui Ren, Xianggao Li, Shirong Wang, Zhijian Chen
Blue-emissive and cross-linkable dimethylmethylene-bridged triphenylamine derivatives were synthesized and their optical and electrochemical properties were investigated.
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Origin of the ligand effect in the cobalt catalyzed regioselective hydroboration of 1,3-diene

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00628A, Paper
Yuhua Liu, ZhongJie Jiang, Jipei Chen
The detailed mechanism and the origin of the ligand-controlled regioselectivity in the cobalt catalyzed hydroboration of 2-substituted 1,3-diene have been investigated.
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Synthesis and photophysical properties of selenopheno[2,3-b]quinoxaline and selenopheno[2,3-b]pyrazine heteroacenes

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00718H, Paper
Amol Sonawane, Atsushi Shimozuma, Taro Udagawa, Masayuki Ninomiya, Mamoru Koketsu
In this paper, we report the novel synthesis of three different heterocycles namely 2-arylselenopheno[2,3-b]quinoxaline, 3-(aryl/alkylselanyl)-2-arylselenopheno[2,3-b]quinoxaline and 6-phenyl-7-(arylselanyl)selenopheno[2,3-b]pyrazine derivatives from the corresponding 2,3-dichloroquinoxaline and 2,3-dichloropyrazine derivatives. Further, photophysical properties were investigated...
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Protein labeling approach to improve lysosomal targeting and efficacy of antibody–drug conjugates

Org. Biomol. Chem., 2020, 18,3229-3233
DOI: 10.1039/D0OB00265H, Communication
Ying Han, Yifan Da, Mingjia Yu, Yaping Cheng, Xin Wang, Jiale Xiong, Guoying Guo, Yan Li, Xianxing Jiang, Xiaoqing Cai
An anti-EGFR nanobody was labeled at the C-terminus with a lysosome-sorting NPGY (Asn-Pro-Gly-Tyr) motif via sortase-mediated ligation to enhance the clathrin-mediated endocytosis.
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Synthesis, structures and photophysical properties of hexacoordinated organosilicon compounds with 2-(2-pyridyl)phenyl groups

Org. Biomol. Chem., 2020, 18,3239-3242
DOI: 10.1039/D0OB00484G, Communication
Shohei Furuta, Toshiaki Mori, Yusuke Yoshigoe, Kohei Sekine, Yoichiro Kuninobu
We synthesised novel air-, water-, heat-, acid-, and base-stable hexacoordinated organosilicon compounds, which contain two C,N-bidentate ligands and form two silafluorene equivalent moieties, with Lewis acid–base interactions.
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Direct recognition and sensitive detection of circular RNA with ligation-based PCR

Org. Biomol. Chem., 2020, 18,3269-3273
DOI: 10.1039/D0OB00625D, Communication
Pengbo Zhang, Na Guo, Kejian Gao, Fengxia Su, Fangfang Wang, Zhengping Li
A sensitive and specific method for circRNA detection is developed through the direct ligation of two ingeniously designed DNA probes.
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Visible light induced 3-position-selective addition of arylpropiolic acids with ethers via C(sp3)–H functionalization

Org. Biomol. Chem., 2020, 18,3258-3262
DOI: 10.1039/D0OB00480D, Communication
Zi-juan Wan, Xiao-feng Yuan, Jun Luo
Although the 2-position-selective decarboxylative coupling or addition of arylpropiolic acids with cyclic ethers has been intensively investigated, selective functionalization of arylpropiolic acids at the 3-position is still a big challenge.
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Synthesis of methylene cyclopropane-fused chromenes and dihydroquinolines by sequential [4 + 2]- and [1 + 2]-annulation

Org. Biomol. Chem., 2020, 18,3303-3311
DOI: 10.1039/D0OB00389A, Paper
Tianyu Lu, Xuange Zhang, Zhiwei Miao
A base promoted sequential [4 + 2]- and [1 + 2]-annulation of 2-hydroxychalcones or 2-tosylaminochalcones with prop-2-ynylsulfonium salts was developed.
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A visible-light-induced “on–off” one-pot synthesis of 3-arylacetylene coumarins with AIE properties

Org. Biomol. Chem., 2020, 18,3346-3353
DOI: 10.1039/D0OB00479K, Paper
Xinjie Wu, Ming Jia, Mengmeng Huang, Jung Keun Kim, Zheng Zhao, Junkai Liu, Jinhu Xi, Yabo Li, Yangjie Wu
A mild one-pot approach to 3-arylacetylene coumarins with potential AIE activities was developed via photosensitizer-free photocatalysis and thermocatalysis.
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Modular synthesis of oligoacetylacetones via site-selective silylation of acetylacetone derivatives

Org. Biomol. Chem., 2020, 18,3297-3302
DOI: 10.1039/D0OB00501K, Paper
Parantap Sarkar, Yuya Inaba, Hayato Shirakura, Tomoki Yoneda, Yasuhide Inokuma
Aliphatic oligoketones with tailored carbonyl and substituent sequences were modularly synthesized utilizing site-selective formation of enol silyl ethers. Their unique conformational preferences in solid-state were revealed by X-ray crystallography.
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Copper-catalyzed direct amination of benzylic hydrocarbons and inactive aliphatic alkanes with arylamines

Org. Biomol. Chem., 2020, 18,3263-3268
DOI: 10.1039/D0OB00491J, Communication
Hua Yao, Bo Xie, Xiaoyang Zhong, Shengzhou Jin, Sen Lin, Zhaohua Yan
A new synthetic method toward direct C–N bond formation through saturated C–H amination of benzylic hydrocarbons and inactive aliphatic alkanes with primary aromatic amines under an inexpensive catalyst/oxidant (Cu/DTBP) system has been developed.
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A base-promoted tandem approach to bicyclic 8-membered ring ketones

Org. Biomol. Chem., 2020, 18,3249-3253
DOI: 10.1039/D0OB00618A, Communication
Emerson E. F. dos Santos, Gabriela F. P. de Souza, Deborah A. Simoni, Airton G. Salles
A base-promoted tandem route toward unprecedented bicyclic furan/8-membered ring ketones is reported.
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KI/TBHP-promoted [3 + 2] cycloaddition of pyrrolo[1,2-a]quinoxalines and N-arylsulfonylhydrazones

Org. Biomol. Chem., 2020, 18,3360-3366
DOI: 10.1039/D0OB00494D, Paper
Zhen Yang, Jing He, Yueting Wei, Weiwei Li, Ping Liu
A series of diverse fused [1,2,4]triazolo[3,4-c]quinoxalines was obtained by an efficient KI/TBHP-promoted [3 + 2] cycloaddition of pyrrolo[1,2-a]quinoxalines and N-arylsulfonylhydrazones.
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