de Driving Force to Detect Alzheimer's Disease Biomarkers: The Application Of A Thioflavine T@Er-MOF Ratiometric Fluorescent Sensor for Smart Detection of Presenilin 1, amyloid β-protein and Acetyl Choline By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00440E, PaperXing Ze Wang, jing du, Nannan Xiao, Yan Zhang, Ling Fei, Jed D. LaCoste, Zhuo Huang, Qian wang, Xin Rui Wang, Bin DingCurrently, the highly sensitive detection of Alzheimer's Disease (AD) biomarkers, namely presenilin 1, amyloid β-protein (Aβ), and acetylcholine (ACh), are vital to helping us prevent and diagnose AD. In this...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de Naked-Eye Sensing of Phytic Acid at Sub-Nanomolar Level in 100% Water Medium by Charge Transfer Complex Derived from off-the-shelf Ingredients By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00671H, PaperNilanjan DeyNaked-eye sensing of phytic acid, one of the most abundant antinutrients, was achieved in 100% water medium using charge transfer complex, comprised of pyranine and methyl viologen. Since both the...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de A homogeneous photoelectrochemical hydrogen sulfide sensor based on the electronic transfer mediated by tetrasulfophthalocyanine By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00302F, PaperXinyang Wang, Huanan Zhao, Zhonghui Chen, Fang Luo, Longhua Guo, Bin Qiu, Zhenyu Lin, Jian WangA homogeneous photoelectrochemical sensor for H2S detection based on the electronic transfer mediated by [Fe(III)PcS4]+ was developed with an un-modified photoelectrode.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de Portable and field-deployed surface plasmon resonance and plasmonic sensors By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00316F, Critical ReviewJean-Francois MassonPlasmonic sensors are portable devices that can be employed in situ for the detection of analytes in environmental sciences, clinical diagnostics, infectious diseases, food, and industrial applications.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de Tetrahedral DNA Nanostructure-decorated Electrochemical Platform for Simple and Ultrasensitive EGFR Genotyping of Plasma ctDNA By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00591F, PaperXuyao Wang, Jianping Wu, Weilin Mao, Xia He, Liming Ruan, Junlan Zhu, Peng Shu, Zhenqi Zhang, Bitao Jiang, Xingguo ZhangGenotyping of the epidermal growth factor receptor (EGFR) mutation status is of great importance in the screening of appropriate advanced non-small cell lung carcinoma (NSCLC) patients to receive superior tyrosine...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de A novel turn-on fluorescent sensor for sensitive detection of glutathione via gold nanoclusters preparation based on controllable ligand-induced etching By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00807A, PaperYun Chen, Xiawei Dong, Youkun Zheng, Yi-Han Wang, Zengchao Guo, Hui Jiang, Xuemei WangIn this study, we report a facile one-pot chemical etching approach to simply and rapidly prepare gold nanoclusters capped with luminol (Lum-AuNCs) in alkaline aqueous solution at room temperature. A...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de Biocompatible Alkyne arms containing Schiff base Fluorescence Indicator for Duel detection of CdII and PbII at Physiological pH and its Application to Live Cell Imaging By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00862A, PaperJebastin Andrews S.G, Benita Jeba Silviya S, Jeyanthi Dharmaraj, Winfred Jebaraj J, Sathya Devi E, C. BalakrishnanAn alkyne arms containing salen-type Schiff base ligand, 6,6'-((1E,1'E)-(1,2-phenylenebis(azanylylidene))bis(ethan-1-yl-1-ylidene))bis(3-(prop-2-yn-1-yloxy)phenol) (H2L), is reported here as a dual chemosensor for CdII and PbII ions. The ligand, H2L was characterized by various spectral...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de Magnetic molecularly imprinted conducting polymer for determination of praziquantel enantiomers in milk By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00703J, PaperTienne Nascimento, Camilla Fonseca Silva, Hanna L Oliveira, Ricky Cássio Santos da Silva, Clébio Soares Nascimento, Keyller Bastos BorgesA new selective adsorbent based on magnetic molecularly imprinted conducting polymer was firstly synthetized and applied to the magnetic solid phase extraction (MSPE) for the determination of PZQ enantiomers in...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de A paper-supported sandwich immunosensor based on upconversion luminescence resonance energy transfer for the visual and quantitative determination of a cancer biomarker in human serum By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/C9AN02307K, PaperMengyuan He, Ning Shang, Lin Shen, Zhi-hong LiuIn this paper, a paper-supported analytical device based on a sandwich immunoreaction and luminescence resonance energy transfer (LRET) was reported for the visual and quantitative determination of a cancer biomarker,...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de An Integrated Microfluidic Platform for Selective and Real-Time Detection of Thrombin Biomarkers using a Graphene FET By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00251H, PaperNiazul Islam Khan, Mohammad Mousazadehkasin, Sujoy Ghosh, John G. Tsavalas, Edward SongLab-on-a-chip technology offers an ideal platform for low-cost, reliable, and easy-to-use diagnostics of key biomarkers needed for early screening of diseases and other health concerns. In this work, a graphene...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de Rapid on-site and naked-eye detection of common nitro pesticides with ionic liquids By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00452A, Paper Kovida, Vikas Sharma, Apurba Lal KonerRapid ‘in-field’ detection of environmentally hazardous organophosphorus and nitro-containing pesticides is highly essential due to the lethal effects caused by the inhibition of the activity of acetylcholinesterase (AChE).To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de Core–shell magnetic microporous covalent organic framework with functionalized Ti(IV) for selective enrichment of phosphopeptides By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00038H, PaperFengjuan Ding, Yameng Zhao, Haiyan Liu, Weibing ZhangWe fabricated a core-shell magnetic Ti4+-functionalized covalent organic framework composite to selectively capture phosphopeptides in biosamples. This method is applicable to achieve rapid, selective and efficient phosphopeptide analysis.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de Acid–base titration using a microfluidic thread-based analytical device (μTAD) By feeds.rsc.org Published On :: Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00522C, PaperPurim Jarujamrus, Akarapong Prakobkij, Sodsai Puchum, Sawida Chaisamdaeng, Rattapol Meelapsom, Wipark Anutrasakda, Maliwan Amatatongchai, Sanoe Chairam, Daniel CitterioThis work presents a novel analytical approach for precise and quick (within 2 minutes) determination of acid and base concentrations (of very small amount) by titration using a microfluidic thread-based analytical device (μTAD).To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de A Simple and Ubiquitous Device for Picric Acid Detection in Latent Fingerprints using Carbon Dots By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00750A, PaperArunkumar Kathiravan, Annasamy Gowri, Srinivasan Venkatesan, Trevor Smith, Muthpandian Ashokkumar, Asha Jhonsi MariadossThis work addresses the synthetic optimization of carbon dots (CDs) and their application in sensing picric acid from latent fingerprint by exploiting a smartphone-based RGB tool. The optimization in the...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de Surface Polymer Imprinted Optical Fibre Sensor for Dose Detection of Dabrafenib By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00434K, PaperChenyang He , Ulises Hernandez Ledezma , Pratik Gurnani, Thais Fedatto Abelha, Kristofer James Thurecht, Ricardo Goncalves Correia , Steve Morgan, Poulam Patel, Cameron Alexander, Sergiy KorposhDabrafenib is one of the most widely used of the new generation of targeted anti-cancer drugs. However, its therapeutic window varies for different patients and so there is an unmet...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de An efficient assay for identification and quantitative evaluation of potential polysialyltransferase inhibitors By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00721H, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Xiaoxiao Guo, Jodie R Malcolm, Marrwa M Ali, Goreti Ribeiro Morais, Steve Shnyder, Paul Loadman, L H Patterson, Robert Andrew FalconerThe polysialyltransferases (polySTs) catalyse the polymerisation of polysialic acid, which plays an important role in tumour metastasis. While assays are available to assess polyST enzyme activity, there is no methodology...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de Phenyl doped graphitic carbon nitride nanosheets for sensing of copper ions in living cells By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00795A, PaperZhiping Song, Yuanteng Xu, Liangqia GuoCopper (Cu) is a vital mental element for human and animals. Monitoring and evaluating the concentration level of Cu2+ in biological body is an effective way to prevent a variety...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de Influence of Hair Treatments on Detection of Antiretrovirals by Mass Spectrometry Imaging By feeds.rsc.org Published On :: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00478B, PaperMac Gilliland, Nicole R White, Bryan Yam, Joseph N Mwangi, Heather MA Prince, Ann Marie K Weideman, Angela DM Kashuba, Elias RosenAnalysis of drugs in hair by mass spectrometry imaging (MSI) has great potential as an objective, long-term measure of medication adherence. However, the fidelity of the chemical record in hair...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
de [ASAP] Nucleic Acid Detection Using CRISPR/Cas Biosensing Technologies By feedproxy.google.com Published On :: Tue, 17 Mar 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00507 Full Article
de [ASAP] Genome-Wide CRISPRi-Based Identification of Targets for Decoupling Growth from Production By feedproxy.google.com Published On :: Tue, 21 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00143 Full Article
de [ASAP] Introduction of the Menaquinone Biosynthetic Pathway into <italic toggle="yes">Rhodobacter sphaeroides</italic> and <italic toggle="yes">de Novo</italic> Synthesis of Menaquinone for Incorporation into He By feedproxy.google.com Published On :: Tue, 21 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.0c00066 Full Article
de [ASAP] Update to Our Reader, Reviewer, and Author Communities—April 2020 By feedproxy.google.com Published On :: Wed, 22 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.0c00216 Full Article
de [ASAP] Determinants for Efficient Editing with Cas9-Mediated Recombineering in <italic toggle="yes">Escherichia coli</italic> By feedproxy.google.com Published On :: Tue, 28 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00440 Full Article
de [ASAP] A Synthetic Genetic Circuit Enables Precise Quantification of Direct Repeat Deletion in Bacteria By feedproxy.google.com Published On :: Tue, 28 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.9b00256 Full Article
de [ASAP] Truncating the Structure of Lipopolysaccharide in <italic toggle="yes">Escherichia coli</italic> Can Effectively Improve Poly-3-hydroxybutyrate Production By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.0c00071 Full Article
de [ASAP] Bacteriophage Inspired Growth-Decoupled Recombinant Protein Production in <italic toggle="yes">Escherichia coli</italic> By feedproxy.google.com Published On :: Thu, 07 May 2020 04:00:00 GMT ACS Synthetic BiologyDOI: 10.1021/acssynbio.0c00028 Full Article
de Franz Freiherr von Eckgher, Fürstbischofs von Freising, alphabetische Sammlung zur Genealogie des bayrischen Adels, Band 4 - BSB Cgm 2268(4 By daten.digitale-sammlungen.de Published On :: Wed, 01 Apr 2020 13:12:02 +0100 Autor: Johann Franz [Freising, Bischof] Erschienen 1695 BSB-Signatur Cgm 2268(4 URN: urn:nbn:de:bvb:12-bsb00003723-2 URL: http://daten.digitale-sammlungen.de/~db/0000/bsb00003723/images/ Full Article
de Genealogia Mändliana (der Freiherr Mändl von und zu Duntenhofen Ursprung und Aufnahme von 1613 - 1719) - BSB Cgm 2128 By daten.digitale-sammlungen.de Published On :: Thu, 16 Apr 2020 13:12:02 +0100 Autor: Erschienen 1701 BSB-Signatur Cgm 2128 URN: urn:nbn:de:bvb:12-bsb00132384-3 URL: http://daten.digitale-sammlungen.de/~db/0013/bsb00132384/images/ Full Article
de Nikolaus von Jeroschin: Deutschordenchronik - BSB Cgm 5249(61 m By daten.digitale-sammlungen.de Published On :: Thu, 16 Apr 2020 13:12:02 +0100 Autor: Nikolaus [von Jeroschin] Erschienen 1351 BSB-Signatur Cgm 5249(61 m URN: urn:nbn:de:bvb:12-bsb00132381-7 URL: http://daten.digitale-sammlungen.de/~db/0013/bsb00132381/images/ Full Article
de Nikolaus von Jeroschin: Deutschordenchronik, Fragment M 2 - BSB Cgm 5249(24 b By daten.digitale-sammlungen.de Published On :: Thu, 16 Apr 2020 13:12:02 +0100 Autor: Nikolaus [von Jeroschin] Erschienen 1351 BSB-Signatur Cgm 5249(24 b URN: urn:nbn:de:bvb:12-bsb00132380-1 URL: http://daten.digitale-sammlungen.de/~db/0013/bsb00132380/images/ Full Article
de A Model Mother By feeds.christianitytoday.com Published On :: 4 characteristics we can learn from Eunice. Full Article
de [ASAP] A Selective Modulator of Peroxisome Proliferator-Activated Receptor ? with an Unprecedented Binding Mode By feedproxy.google.com Published On :: Mon, 20 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01786 Full Article
de [ASAP] Imidazo[1,2-<italic toggle="yes">a</italic>]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells By feedproxy.google.com Published On :: Mon, 20 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01910 Full Article
de [ASAP] Synthesis and Structure–Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy By feedproxy.google.com Published On :: Tue, 21 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01961 Full Article
de [ASAP] Pyridine-Embedded Phenothiazinium Dyes as Lysosome-Targeted Photosensitizers for Highly Efficient Photodynamic Antitumor Therapy By feedproxy.google.com Published On :: Tue, 21 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00280 Full Article
de [ASAP] Discovery of Orally Bioavailable Chromone Derivatives as Potent and Selective BRD4 Inhibitors: Scaffold Hopping, Optimization, and Pharmacological Evaluation By feedproxy.google.com Published On :: Wed, 22 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00035 Full Article
de [ASAP] Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands By feedproxy.google.com Published On :: Thu, 23 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01835 Full Article
de [ASAP] Update to Our Reader, Reviewer, and Author Communities—April 2020 By feedproxy.google.com Published On :: Thu, 23 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00641 Full Article
de [ASAP] Discovery of Peptide Boronate Derivatives as Histone Deacetylase and Proteasome Dual Inhibitors for Overcoming Bortezomib Resistance of Multiple Myeloma By feedproxy.google.com Published On :: Thu, 23 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b02161 Full Article
de [ASAP] Correction to Toggling Preassembly with Single-Site Mutation Switches the Cytotoxic Mechanism of Cationic Amphipathic Peptides By feedproxy.google.com Published On :: Fri, 24 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00608 Full Article
de [ASAP] Positional Analogue Scanning: An Effective Strategy for Multiparameter Optimization in Drug Design By feedproxy.google.com Published On :: Fri, 24 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b02092 Full Article
de [ASAP] Discovery and Development of S6821 and S7958 as Potent TAS2R8 Antagonists By feedproxy.google.com Published On :: Fri, 24 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00388 Full Article
de [ASAP] Discovery and Structure–Activity Relationship Study of (<italic toggle="yes">Z</italic>)-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors By feedproxy.google.com Published On :: Mon, 27 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00227 Full Article
de [ASAP] Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies By feedproxy.google.com Published On :: Wed, 29 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00202 Full Article
de [ASAP] Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities By feedproxy.google.com Published On :: Wed, 29 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00015 Full Article
de [ASAP] Design and Characterization of the First Selective and Potent Mechanism-Based Inhibitor of Cytochrome P450 4Z1 By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00101 Full Article
de [ASAP] Design of Radiolabeled Analogs of Minigastrin by Multiple Amide-to-Triazole Substitutions By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01937 Full Article
de [ASAP] Degradation versus Inhibition: Development of Proteolysis-Targeting Chimeras for Overcoming Statin-Induced Compensatory Upregulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase By feedproxy.google.com Published On :: Mon, 04 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00339 Full Article
de [ASAP] Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00395 Full Article
de [ASAP] Structural Fingerprints of an Intact Monoclonal Antibody Acquired under Formulated Storage Conditions via <sup>15</sup>N Direct Detection Nuclear Magnetic Resonance By feedproxy.google.com Published On :: Wed, 06 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00231 Full Article
