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Double dipping in an NIH loan repayment program, and using undersea cables as seismic sensors

The National Institutes of Health’s largest loan repayment program was conceived to help scientists pay off school debts without relying on industry funding. But a close examination of the program by investigative correspondent Charles Piller has revealed that many participants are taking money from the government to repay their loans, while at the same time taking payments from pharmaceutical companies. Piller joins Host Sarah Crespi to talk about the steps he took to uncover this double dipping and why ethicists say this a conflict of interest.   Sarah also talks with Nate Lindsey, a Ph.D. candidate at the University of California, Berkeley, about turning a 50-kilometer undersea fiber optic cable designed to move data into a sensor for activity in the ocean and the land underneath. During a 4-day test in Monterey Bay, California, the cable detected earthquakes, faults, waves, and even ocean-going storms. For this month’s books segment, Kiki Sandford talks with Dan Hooper about his book At the Edge of Time: Exploring the Mysteries of Our Universe’s First Seconds.   You can find more books segments on the Books et al. blog.   This week’s episode was edited by Podigy.   Ads on this week’s show: McDonalds; Salk’s Where Cures Begin podcast   Download the transcript (PDF) Listen to previous podcasts.   About the Science Podcast




de

Debating lab monkey retirement, and visiting a near-Earth asteroid

After their life as research subjects, what happens to lab monkeys? Some are euthanized to complete the research, others switch to new research projects, and some retire from lab life. Should they retire in place—in the same lab under the care of the same custodians—or should they be sent to retirement home–like sanctuaries? Online News Editor David Grimm joins host Sarah Crespi to discuss recently penned legislation that pushes for monkey retirements and a new collaboration between universities and sanctuaries to create a retirement pipeline for these primates. Sarah also talks with Dante Lauretta, principal investigator for NASA’s Origins, Spectral Interpretation, Resource Identification, Security, Regolith Explorer (OSIRIS-REx) and a professor at the University of Arizona in Tucson, about the latest news from the asteroid Bennu. Within 1 week of beginning its orbit of the asteroid, OSIRIS-REx was able to send back surprising images of the asteroid ejecting material. It’s extremely rocky surface also took researchers by surprise and forced a recalculation of the sample return portion of the craft’s mission. This week’s episode was edited by Podigy. Ads on this week’s show: McDonalds; Parcast’s Natural Disasters podcast; KiwiCo Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast




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Squeezing two people into an MRI machine, and deciding between what’s reasonable and what’s rational

Getting into an MRI machine can be a tight fit for just one person. Now, researchers interested in studying face-to-face interactions are attempting to squeeze a whole other person into the same tube, while taking functional MRI (fMRI) measurements. Staff Writer Kelly Servick joins host Sarah Crespi to talk about the kinds of questions simultaneous fMRIs might answer. Also this week, Sarah talks with Igor Grossman, director of the Wisdom and Culture Lab at the University of Waterloo, about his group’s Science Advances paper on public perceptions of the difference between something being rational and something being reasonable. This week’s episode was edited by Podigy. Read a transcript (PDF) Listen to previous podcasts. About the Science Podcast




de

Dog noses detect heat, the world faces coronavirus, and scientists search for extraterrestrial life

On this week’s show, Online News Editor David Grimm joins host Sarah Crespi to discuss how dogs’ cold noses may be able to sense warm bodies. Read the research. International News Editor Martin Enserink shares the latest from our reporters covering coronavirus. And finally, from a recording made at this year’s AAAS annual meeting, host Meagan Cantwell talks with Jill Tarter, chair emeritus at the SETI Institute, about the newest technologies being used to search for alien life, what a positive signal would look like, and how to inform the public if extraterrestrial life ever were detected. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF).




de

Science’s leading role in the restoration of Notre Dame, and the surprising biology behind how our body develops its tough skin

On this week’s show, freelance writer Christa Lesté-Lasserre talks with host Sarah Crespi about the scientists working on the restoration of Notre Dame, from testing the changing weight of wet limestone, to how to remove lead contamination from four-story stained glass windows. As the emergency phase of work winds down, scientists are also starting to use the lull in tourist activity to investigate the mysteries of the cathedral’s construction. Also this week, Felipe Quiroz, an assistant professor in the biomedical engineering department at the Georgia Institute of Technology and Emory University, talks with Sarah about his paper on the cellular mechanism of liquid-liquid phase separation in the formation of the tough outer layer of the skin. Liquid-liquid phase separation is when two liquids “demix,” or separate, like oil and water. In cells, this process created membraneless organelles that are just now starting to be understood. In this work, Quiroz and colleagues create a sensor for phase separation in the cell that works in living tissue, and show how phase separation is tied to the formation of the outer layers of skin in mice. Read the related Insight. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: r. nial bradshaw/Flickr; Music: Jeffrey Cook]




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Why some diseases come and go with the seasons, and how to develop smarter, safer chemicals

On this week’s show, host Joel Goldberg gets an update on the coronavirus pandemic from Senior Correspondent Jon Cohen. In addition, Cohen gives a rundown of his latest feature, which highlights the relationship between diseases and changing seasons—and how this relationship relates to a potential coronavirus vaccine. Also this week, from a recording made at this year’s AAAS annual meeting in Seattle, host Meagan Cantwell speaks with Alexandra Maertens, director of the Green Toxicology initiative at Johns Hopkins University, Baltimore, about the importance of incorporating nonanimal testing methods to study the adverse effects of chemicals. This week’s episode was produced with help from Podigy. Download a transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Let Ideas Compete/Flickr; Music: Jeffrey Cook] 




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How COVID-19 disease models shape shutdowns, and detecting emotions in mice

On this week’s show, Contributing Correspondent Kai Kupferschmidt talks with host Sarah Crespi about modeling coronavirus spread and the role of forecasts in national lockdowns and other pandemic policies. They also talk about the launch of a global trial of promising treatments. See all of our News coverage of the pandemic here. See all of our Research and Editorials here. Also this week, Nadine Gogolla, research group leader at the Max Planck Institute of Neurobiology, talks with Sarah about linking the facial expressions of mice to their emotional states using machine learning. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF)




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Vacuum in Particle Accelerators: Modelling, Design and Operation of Beam Vacuum Systems


 
A unique guide on how to model and make the best vacuum chambers

Vacuum in Particle Accelerators offers a comprehensive overview of ultra-high vacuum systems that are used in charge particle accelerators. The book?s contributors ? noted experts in the field ? also highlight the design and modeling of vacuum particle accelerators.

The book reviews vacuum requirements, identifies sources of gas in vacuum chambers and explores methods of removing them.

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Ferroic Materials for Smart Systems: From Fundamentals to Device Applications


 
Presents state-of-the-art knowledge?from basic insights to applications?on ferroic materials-based devices

This book covers the fundamental physics, fabrication methods, and applications of ferroic materials and covers bulk, thin films, and nanomaterials. It provides a thorough overview of smart materials and systems involving the interplays among the mechanical strain, electrical polarization, magnetization, as well as heat and light. Materials presented

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Crystallography and Crystal Defects, 3rd Edition


 

The classic book that presents a unified approach to crystallography and the defects found within crystals, revised and updated

This new edition of Crystallography and Crystal Defectsexplains the modern concepts of crystallography in a clear, succinct manner and shows how to apply these concepts in the analyses of point, line and planar defects in crystalline materials. 

Fully revised and updated, this book now includes:



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Mira & Misha try their hands at embroidery

Shahid Kapoor and Mira Rajput are reportedly self-quarantining in Punjab with their kids Misha and Zain. The duo has been making the most of their free time amid the lockdown and spending time with the family.




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Pic: Sonam seems to be lost in deep thoughts

Yesterday, Sonam Kapoor celebrated her second anniversary with her husband Anand Ahuja.




de

Drunken brawl results in death

TIRUVARUR Rajkumar (23) of Maavur near Tiruvarur reportedly died after he was attacked by a group of persons at Pinnavasal hamlet on Thursday night wh




de

Former Delhi Police Commissioner recalls the day terror struck Parliament

Nearly 20 years ago, when a suicide squad stormed the complex, the author was among the first to appear on the scene.




de

Understanding the Dalai Lama

The author also reveals the Dalai Lama to be a sophisticated thinker and consummate scholar, one whose feet remain firmly on the ground, a trait often obscured by his broken English




de

Capitalism reconsidered

Book review of CAPITAL AND IDEOLOGY




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How Conzerv Systems and Schneider Electric managed a tricky biz of merger

Most acquisitions fail because of a cultural clash. But Conzerv Systems and Schneider Electric managed this thorny issue successfully.




de

From democracy to tyranny

Peter Fritzsche's answer to these questions has been to go back and reassess what we think we know about Hitler's rise




de

Product :: CMO's Periodic Table, The: A Renegade's Guide to Marketing




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Product :: CMO's Periodic Table, The: A Renegade's Guide to Marketing




de

Product :: Swift for Beginners: Develop and Design, 2nd Edition




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Product :: Build watchOS Apps: Develop and Design




de

Product :: Foundations of Digital Art and Design with Adobe Creative Cloud, 2nd Edition




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Product :: Foundations of Digital Art and Design with Adobe Creative Cloud, 2nd Edition




de

On the State: Lectures at the Collège de France, 1989 - 1992


What is the nature of the modern state? How did it come into being and what are the characteristics of this distinctive field of power that has come to play such a central role in the shaping of all spheres of social, political and economic life?

In this major work the great sociologist Pierre Bourdieu addresses these fundamental questions. Modifying Max Weber’s famous definition, Bourdieu defines the state in terms of the monopoly of legitimate physical

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Can Science Resolve the Nature / Nurture Debate?


 
Following centuries of debate about "nature and nurture" the discovery of DNA established the idea that nature (genes) determines who we are, relegating nurture (environment) to icing on the cake.

Since the 1950s, the new science of epigenetics has demonstrated how cellular environments and certain experiences and behaviors influence gene expression at the molecular level, with significant implications for health and wellbeing. To the amazement of

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Companion to Women's and Gender Studies


 

A comprehensive overview of the interdisciplinary field of Women's and Gender Studies, featuring original contributions from leading experts from around the world

The Companion to Women's and Gender Studies is a comprehensive resource for students and scholars alike, exploring the central concepts, theories, themes, debates, and events in this dynamic field. Contributions from leading scholars and researchers cover a wide range of topics while providing



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REVEALED: How much India <em>really</em> spends on defence

'India is ahead only of Pakistan in the amount spent on each soldier a year.'




de

Ultra-trace determination of domoic acid in the Ebro Delta estuary by SPE-HILIC-HRMS

Anal. Methods, 2020, 12,1966-1974
DOI: 10.1039/C9AY02617G, Paper
Open Access
Cristina Bosch-Orea, Josep Sanchís, Damiá Barceló, Marinella Farré
Marine phytoplankton, such as diatoms, are responsible for a considerable part of carbon fixation and form the basis of the marine food web.
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de

A fluorescence-positioned hybridization chain reaction system for sensitive detection of Salmonella in milk

Anal. Methods, 2020, 12,1958-1965
DOI: 10.1039/D0AY00184H, Paper
Guotai Yang, Shuang Yu, Yang Liu, Jin Huang, Qianying Li, Zoraida P. Aguilar, Hengyi Xu
In this study, a fluorescence-positioned hybridization chain reaction (HCR) system for the detection of single-stranded DNA (ssDNA) specific to Salmonella was developed.
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de

A membraneless gas-trapping device for cyanide detection and quantification

Anal. Methods, 2020, 12,2009-2015
DOI: 10.1039/D0AY00245C, Paper
Chatipat Lorpaiboon, Wanutcha Lorpaiboon, Manchuta Dangkulwanich
A novel device for trapping gaseous compounds was invented and employed to create a user-friendly cyanide test kit for aqueous solutions.
The content of this RSS Feed (c) The Royal Society of Chemistry




de

A deep learning approach to identify association of disease–gene using information of disease symptoms and protein sequences

Anal. Methods, 2020, 12,2016-2026
DOI: 10.1039/C9AY02333J, Paper
Xingyu Chen, Qixing Huang, Yang Wang, Jinlong Li, Haiyan Liu, Yun Xie, Zong Dai, Xiaoyong Zou, Zhanchao Li
Prediction of disease–gene association based on a deep convolutional neural network.
The content of this RSS Feed (c) The Royal Society of Chemistry




de

The development and validation of a GC-MS method for the quantification of glycolaldehyde formed from carbohydrate fragmentation processes

Anal. Methods, 2020, 12,1975-1987
DOI: 10.1039/C9AY02639H, Paper
Samin Fathalinejad, Esben Taarning, Peter Christensen, Jan H. Christensen
Glycolaldehyde is a small sugar-like molecule that is readily formed by the thermochemical fragmentation of carbohydrates and it has similar physico-chemical properties to sugars.
The content of this RSS Feed (c) The Royal Society of Chemistry




de

Fast determination of five chiral antipsychotic drugs using dispersive liquid–liquid microextraction combined with capillary electrophoresis

Anal. Methods, 2020, 12,2002-2008
DOI: 10.1039/C9AY02776A, Paper
Ming-Mu Hsieh, Tai-Chia Chiu, Szu-Hua Chen
This study developed a new method for the extraction, clean up, chiral separation, and determination of five pairs of phenothiazine drugs using ultrasound-assisted dispersive liquid–liquid microextraction combined with capillary electrophoresis.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A bimetallic PtPd hybrid nanostructure-amplified enzyme-free conductometric immunoassay for lipocalin-2 in renal cell carcinoma on an interdigitated micro-comb electrode

Anal. Methods, 2020, 12,1988-1994
DOI: 10.1039/C9AY02525A, Paper
Chaoqun Huang, Fengling Zhang, Qingshui Wang, Yao Lin, Jiyi Huang
A new enzyme-free conductometric immunoassay based on bimetallic PtPd hybrid nanostructures was developed for the sensitive determination of lipocalin-2 in renal cell carcinoma.
The content of this RSS Feed (c) The Royal Society of Chemistry




de

3D-printed microfluidic device with in-line amperometric detection that also enables multi-modal detection

Anal. Methods, 2020, 12,2046-2051
DOI: 10.1039/D0AY00368A, Technical Note
Elizabeth A. Hayter, Andre D. Castiaux, R. Scott Martin
A 3D-printed microfluidic device with amperometric detection employs a parallel-opposed electrode configuration, with threaded electrodes being in contact with the flow stream. This makes downstream detection of ATP via chemiluminescence possible.
The content of this RSS Feed (c) The Royal Society of Chemistry




de

NMR-based plasma metabonomics in hyperlipidemia mice

Anal. Methods, 2020, 12,1995-2001
DOI: 10.1039/D0AY00487A, Paper
Yun Li, Xiu-ju Zhao
Hyperlipidemia dynamics need to be elucidated.
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de

Evaluation of segmented non-target data acquisition (SWATH/vDIA) in a QToF and QOrbitrap for pesticide residue analysis

Anal. Methods, 2020, 12,2027-2038
DOI: 10.1039/D0AY00290A, Paper
Łukasz Rajski, Iciar Beraza, María José Gómez Ramos, Carmen Ferrer, Amadeo R. Fernández-Alba
Two high-resolution instruments (a QToF and a QOrbitrap) were used to evaluate a segmented non-target MS2 (SWATH/vDIA) acquisition for pesticide residue analysis.
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de

Bio-assay of non-amidated progastrin-derived peptide (G17-Gly) using Tailor-made recombinant antibody fragment and phages display method: A biomedical analysis

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00627K, Paper
Deniz Sadighbayan, Mohammad Reza Tohid-kia, Tayebeh Mehdipour, Mohammad Hasanzadeh, Ahmad Yari Khosroushahi
In this research, four novel and sensitive immunosensor for electrochemical determination of G17-Gly were designed based on signal amplification and tailor-made recombinant antibody technology. Anti-G17-Glyantibody fragments (i.e. scFv and VL...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Determination of total and bioavailable of As and Sb in children’s paints using MSFIA system coupled to HG-AFS

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/C9AY02779C, Paper
Dayara Virginia Lino Ávila, Sidnei OLIVEIRA Souza, Victor Cerdà, Rennan Geovanny Oliveira Araujo
In this work, the application of Doehlert design for the optimisation aiming the determination of As and Sb in gouache and tempera children's paints, using multi-syringe flow injection analysis (MSFIA)...
The content of this RSS Feed (c) The Royal Society of Chemistry




de

Detection of Nutrition and Toxic Elements in Pakistani Pepper Powders Using Laser Induced Breakdown Spectroscopy

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00630K, Paper
Imran Rehan, Kamran Rehan, Muhammad Zubair Khan, Sabiha Sultana, Riaz Khan, Hamdullah Khan
In the current paper, we applied laser induced breakdown spectroscopy (LIBS) to determine the elemental distribution of nutritional and trace heavy metals in pepper powders available in Pakistan using standard...
The content of this RSS Feed (c) The Royal Society of Chemistry




de

Detection of prostate-specific antigen in semen using DNA aptamers: an application of nucleic acid aptamers in forensic body fluid identification

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00371A, Paper
Tetsuya Satoh, Seiya Kouroki, Yusuke Kitamura, Toshihiro Ihara, Kazutoshi Matsumura, Susumu Iwase
In forensics, body fluid identification plays an important role because it aids in reconstructing the crime scene. Therefore, it is essential to develop simple and reliable techniques for body fluid...
The content of this RSS Feed (c) The Royal Society of Chemistry




de

A dual-functional PDMS-assisted paper-based SERS platform for reliable detection of thiram residue both on fruit surface and in juice

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00483A, Paper
Shuang Lin, Wuliji Hasi, Siqingaowa Han, Xiang Lin, Li Wang
In this work, a dual-functional SERS platform was developed via a paper-based SERS substrate with the aid of hydrophobic Polydimethylsiloxane (PDMS) for effective and reliable measurements of thiram on fruit...
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A novel microfluidic paper-based analytical device based on chemiluminescence for the determination of β-agonists in swine hair

Anal. Methods, 2020, Advance Article
DOI: 10.1039/C9AY02754H, Paper
Wei Li, Yong Luo, Xiqing Yue, Junrui Wu, Rina Wu, Yu Qiao, Qing Peng, Bo Shi, Bingcheng Lin, Xu Chen
β-Agonists are illegal feed additives in the feed industries of many countries, especially China.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A simple and rapid method for blood plasma separation driven by capillary force with an application on protein detection

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00240B, Paper
Qingxue Gao, Yongjia Chang, Qingmei Deng, Hui You
Blood plasma separation is a vital sample pre-treatment procedure for microfluidic devices of blood diagnostic, which requires reliability and speediness. In this work, we propose a novel and simple method...
The content of this RSS Feed (c) The Royal Society of Chemistry




de

Experimental design and optimisation (5): an introduction to optimisation

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY90037K, AMC Technical Brief
Analytical Methods Committee AMCTB no. 95
This Technical Brief outlines the basic principles of optimisation, and introduces some of the most commonly used approaches.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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de

Effective methods for the determination of triphenyltin residues in surface water and soil samples by high-performance liquid chromatography with tandem mass spectrometry

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00329H, Paper
Gabriel C. dos Santos, Állisson A. da S. Avellar, Rômulo de O. Schwaickhardt, Nelson M. G. Bandeira, Filipe F. Donato, Osmar D. Prestes, Renato Zanella
Monitoring of triphenyltin (TPhT) in the environment, particularly to control its misuse in agriculture, is of great importance because of its high toxicity.
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de

Development of a magnetic dispersive micro-solid-phase extraction method based on a deep eutectic solvent as a carrier for the rapid determination of meloxicam in biological samples

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00095G, Paper
Samira Rastbood, Mohammad Reza Hadjmohammadi, Seyedeh Maedeh Majidi
An environmentally friendly magnetic dispersive micro solid phase extraction based on a deep eutectic solvent as a carrier and disperser of adsorbents.
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de

Rapid detection of quality of Japanese fermented soy sauce using near-infrared spectroscopy

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00521E, Paper
Shuo Wang, Takehiro Tamura, Nobuyuki Kyouno, Xiaofang Liu, Han Zhang, Yoshinobu Akiyama, Jie Yu Chen
The application of NIR spectroscopy has great potential as an alternative quality control method, which provides a robust model for routinely estimating the final quality of soy sauce production rapidly and economically.
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de

Dopamine-modified magnetic graphene oxide as a recoverable sorbent for the preconcentration of metal ions by an effervescence-assisted dispersive micro solid-phase extraction procedure

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00522C, Paper
Basira Karbalaie, Maryam Rajabi, Bahareh Fahimirad
Nanomagnetic graphene oxide modified with dopamine (GO–Fe3O4–DA) was synthesized via a very simple procedure.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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